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ONTOLOGY REPORT - ANNOTATIONS

Term:regulation of insulin secretion
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Accession:GO:0050796 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the regulated release of insulin.


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regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALOX5 arachidonate 5-lipoxygenase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:90,859,209...90,907,084
Ensembl chr14:90,859,016...90,907,094 		JBrowse link
G ARNTL aryl hydrocarbon receptor nuclear translocator like involved_in ISO (MGI:4819446|PMID:20562852) UniProt PMID:20562852 MGI:4819446 NCBI chr 2:45,895,637...46,025,174
Ensembl chr 2:45,895,289...45,988,570 		JBrowse link
G CARTPT CART prepropeptide ISO RGD PMID:16443761 RGD:2313632 NCBI chr16:48,043,558...48,045,592
Ensembl chr16:48,043,492...48,045,592 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr12:39,652,731...39,659,121
Ensembl chr12:39,648,598...39,659,118 		JBrowse link
G CELA2A chymotrypsin-like elastase family, member 2A involved_in ISS UniProt GO_REF:0000024 NCBI chr 6:74,691,653...74,707,598
Ensembl chr 6:74,691,653...74,707,598 		JBrowse link
G CLOCK clock circadian regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:54,793,323...54,910,192
Ensembl chr 8:54,793,342...54,877,777 		JBrowse link
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19644453 RGD:2314628 NCBI chr 1:56,466,022...56,493,275
Ensembl chr 1:56,467,835...56,492,602 		JBrowse link
G CPT1A carnitine palmitoyltransferase 1A ISO RGD PMID:11988095 RGD:1298597 NCBI chr 2:4,250,642...4,293,914
Ensembl chr 2:4,233,099...4,293,911 		JBrowse link
G EIPR1 EARP complex and GARP complex interacting protein 1 involved_in ISO PMID:3172165 UniProt PMID:3172165 RGD:25671404 NCBI chr 3:131,360,898...131,435,619
Ensembl chr 3:131,360,883...131,435,579 		JBrowse link
G ENSA endosulfine alpha acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:9653196) MGI
Ensembl		 PMID:9653196 GO_REF:0000107 NCBI chr 4:98,527,902...98,535,647
Ensembl chr 4:98,527,907...98,542,959 		JBrowse link
G G6PC2 glucose-6-phosphatase catalytic subunit 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:75,382,442...75,388,662
Ensembl chr15:75,382,313...75,390,150 		JBrowse link
G GCG glucagon involved_in
acts_upstream_of_or_within		 ISS
ISO		 (PMID:14736883) UniProt
MGI		 PMID:14736883 GO_REF:0000024 NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,560...68,810,242 		JBrowse link
G GCK glucokinase involved_in IEA Ensembl
TreeGrafter		 GO_REF:0000107 GO_REF:0000118 NCBI chr18:50,979,167...51,024,500
Ensembl chr18:50,979,167...51,029,844 		JBrowse link
G GIP gastric inhibitory polypeptide involved_in IEA InterPro GO_REF:0000002 NCBI chr12:25,160,783...25,167,952
Ensembl chr12:25,160,789...25,167,940 		JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 8:113,952,561...114,005,510
Ensembl chr 8:113,950,034...114,005,511 		JBrowse link
G HNF4A hepatocyte nuclear factor 4 alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:46,783,772...46,847,505
Ensembl chr17:46,783,777...46,847,500 		JBrowse link
G IFNG interferon gamma involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:32,477,906...32,482,670
Ensembl chr 5:32,477,906...32,482,670 		JBrowse link
G IL6 interleukin 6 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:91,506,421...91,510,830
Ensembl chr 9:91,506,421...91,511,263 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:41,756,637...41,760,340
Ensembl chr 2:41,757,356...41,765,555 		JBrowse link
G LEP leptin involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16513828) Ensembl
MGI		 PMID:16513828 GO_REF:0000107 NCBI chr18:20,106,867...20,124,071
Ensembl chr18:20,106,868...20,123,323 		JBrowse link
G LOC110258578 interleukin-1 beta-like involved_in ISO (PMID:8383325) BHF-UCL PMID:8383325
G MTNR1B melatonin receptor 1B involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:25,556,756...25,557,792
Ensembl chr 9:25,545,390...25,558,054 		JBrowse link
G MYL7 myosin light chain 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,026,436...51,028,917
Ensembl chr18:50,979,167...51,029,844 		JBrowse link
G NOS2 nitric oxide synthase 2 involved_in ISO (PMID:8383325) BHF-UCL PMID:8383325 NCBI chr12:44,174,944...44,219,875
Ensembl chr12:44,174,948...44,218,146 		JBrowse link
G PDE3B phosphodiesterase 3B acts_upstream_of_or_within ISO (PMID:14736883) MGI PMID:14736883 NCBI chr 2:44,416,934...44,614,075
Ensembl chr 2:44,412,833...44,726,216 		JBrowse link
G PER2 period circadian regulator 2 involved_in ISO (MGI:5319572|PMID:22504074) UniProt PMID:22504074 MGI:5319572 NCBI chr15:137,793,419...137,837,854
Ensembl chr15:137,793,422...137,837,070 		JBrowse link
G PICK1 protein interacting with PRKCA 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:9,808,444...9,829,677
Ensembl chr 5:9,808,451...9,825,539 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta involved_in ISO PMID:11978799 UniProt PMID:11978799 RGD:8553382 NCBI chr14:76,239,497...76,305,345
Ensembl chr14:76,248,841...76,305,328 		JBrowse link
G RFX3 regulatory factor X3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:218,340,427...218,647,389
Ensembl chr 1:218,360,718...218,640,923 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:44,765,451...44,826,884
Ensembl chr 1:44,765,451...44,823,510 		JBrowse link
G SLC16A1 solute carrier family 16 member 1 involved_in ISO (MGI:5465432|PMID:22522610) UniProt PMID:22522610 MGI:5465432 NCBI chr 4:107,510,920...107,547,609
Ensembl chr 4:107,494,463...107,641,703 		JBrowse link
G SLC25A22 solute carrier family 25 member 22 involved_in ISO PMID:19584051 UniProt PMID:19584051 RGD:151665733 NCBI chr 2:491,288...498,773
Ensembl chr 2:491,293...498,767 		JBrowse link
G SLC8B1 solute carrier family 8 member B1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:38,773,396...38,808,261
Ensembl chr14:38,773,407...38,808,265 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18178930) Ensembl
MGI		 PMID:18178930 GO_REF:0000107 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
G SSTR5 somatostatin receptor 5 involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:15919085) TreeGrafter
MGI
GO_Central		 PMID:15919085 GO_REF:0000033 GO_REF:0000118 NCBI chr 3:40,756,465...40,758,111
Ensembl chr 3:40,756,457...40,762,895 		JBrowse link
G SYT7 synaptotagmin 7 involved_in ISO (MGI:3773625|PMID:18308938) RGD
UniProt		 PMID:17709608 PMID:18308938 MGI:3773625 RGD:2311143 NCBI chr 2:9,947,962...10,012,713
Ensembl chr 2:9,947,925...10,012,496 		JBrowse link
G SYT9 synaptotagmin 9 ISO RGD PMID:16165130 RGD:2311147 NCBI chr 9:2,191,757...2,395,157
Ensembl chr 9:2,191,765...2,391,921 		JBrowse link
G TCIRG1 T cell immune regulator 1, ATPase H+ transporting V0 subunit a3 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17046993) Ensembl
MGI		 PMID:17046993 GO_REF:0000107 NCBI chr 2:4,844,627...4,860,562
Ensembl chr 2:4,844,637...4,860,498 		JBrowse link
G TFAP2B transcription factor AP-2 beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:44,745,653...44,774,563
Ensembl chr 7:44,745,827...44,770,606 		JBrowse link
G TNF tumor necrosis factor involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:23,699,635...23,702,393
Ensembl chr 7:23,699,628...23,702,416 		JBrowse link
G UQCC2 ubiquinol-cytochrome c reductase complex assembly factor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 7:29,902,089...29,929,802
Ensembl chr 7:29,899,043...29,929,795 		JBrowse link
negative regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 involved_in ISO
IEA		 RGD
Ensembl		 PMID:15163199 GO_REF:0000107 RGD:1598646 NCBI chr 2:41,666,974...41,754,624
Ensembl chr 2:41,666,909...41,754,620 		JBrowse link
G ACVR1C activin A receptor type 1C involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:18480258) Ensembl
MGI		 PMID:18480258 GO_REF:0000107 NCBI chr15:64,452,632...64,529,329
Ensembl chr15:64,455,989...64,529,107 		JBrowse link
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:10952463)
(PMID:17992256), (PMID:1898674)
(PMID:1898674)		 BHF-UCL
MGI		 PMID:1898674 PMID:10952463 PMID:17992256 NCBI chr14:121,469,572...121,470,924
Ensembl chr14:121,469,527...121,470,924 		JBrowse link
G BMP8A bone morphogenetic protein 8a involved_in ISO (PMID:22579288) UniProt PMID:22579288 NCBI chr 6:95,322,454...95,366,546 JBrowse link
G CCN3 cellular communication network factor 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:19,505,698...19,514,481
Ensembl chr 4:19,505,701...19,514,406 		JBrowse link
G CHGA chromogranin A involved_in IBA
IEA		 GO_Central
TreeGrafter		 GO_REF:0000033 GO_REF:0000118 NCBI chr 7:114,345,542...114,357,799
Ensembl chr 7:114,345,305...114,358,075 		JBrowse link
G DRD2 dopamine receptor D2 ISO RGD PMID:18216393 RGD:2311570 NCBI chr 9:41,068,618...41,135,262
Ensembl chr 9:41,068,779...41,133,599 		JBrowse link
G F2RL1 F2R like trypsin receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,732,082...85,747,552
Ensembl chr 2:85,732,189...85,750,858 		JBrowse link
G FAM3D FAM3 metabolism regulating signaling molecule D involved_in ISO (PMID:12160727) UniProt PMID:12160727 NCBI chr13:40,375,536...40,456,057 JBrowse link
G FBN1 fibrillin 1 involved_in ISO (MGI:6442875|PMID:30997682) UniProt PMID:30997682 MGI:6442875 NCBI chr 1:123,102,011...123,359,649
Ensembl chr 1:123,102,009...123,359,649 		JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,899,879...44,904,461
Ensembl chr 6:44,901,159...44,904,459 		JBrowse link
G FFAR3 free fatty acid receptor 3 involved_in ISO (PMID:25581519)
(PMID:26091414), (PMID:32073900)		 MGI PMID:25581519 PMID:26091414 PMID:32073900 NCBI chr 6:44,844,149...44,845,172 JBrowse link
G FOXO1 forkhead box O1 involved_in ISS UniProt GO_REF:0000024 NCBI chr11:15,317,222...15,410,059
Ensembl chr11:15,317,124...15,410,473 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide acts_upstream_of_or_within
involved_in		 ISO
IEA
ISS		 PMID:17130496
(PMID:17130496)		 MGI
Ensembl
UniProt		 PMID:17130496 GO_REF:0000024 GO_REF:0000107 RGD:8553721 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G GHSR growth hormone secretagogue receptor acts_upstream_of_or_within ISO PMID:17130496 MGI PMID:17130496 RGD:8553721 NCBI chr13:110,981,465...111,006,149
Ensembl chr13:110,983,298...111,038,324 		JBrowse link
G GNAO1 G protein subunit alpha o1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:29,416,574...29,592,874
Ensembl chr 6:29,417,603...29,592,706 		JBrowse link
G GNAZ G protein subunit alpha z involved_in ISO (PMID:18096703) MGI PMID:18096703 NCBI chr14:49,132,012...49,174,114
Ensembl chr14:49,132,013...49,174,108 		JBrowse link
G HADH hydroxyacyl-CoA dehydrogenase ISO RGD PMID:17491019 RGD:2302227 NCBI chr 8:113,952,561...114,005,510
Ensembl chr 8:113,950,034...114,005,511 		JBrowse link
G HDAC1 histone deacetylase 1 ISO RGD PMID:22772764 RGD:9590127 NCBI chr 6:88,749,611...88,785,220
Ensembl chr 6:88,749,634...88,785,411 		JBrowse link
G INHBB inhibin subunit beta B involved_in
acts_upstream_of_or_within		 ISS
ISO
IEA		 (PMID:18480258) UniProt
MGI
Ensembl		 PMID:18480258 GO_REF:0000024 GO_REF:0000107 NCBI chr15:30,999,994...31,004,405
Ensembl chr15:30,999,520...31,004,405 		JBrowse link
G IRS1 insulin receptor substrate 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:128,245,846...128,307,321
Ensembl chr15:128,245,846...128,307,284 		JBrowse link
G KCNB1 potassium voltage-gated channel subfamily B member 1 involved_in IEA
ISS		 Ensembl
UniProt		 GO_REF:0000024 GO_REF:0000107 NCBI chr17:51,032,163...51,152,566
Ensembl chr17:51,039,987...51,142,644 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:41,756,637...41,760,340
Ensembl chr 2:41,757,356...41,765,555 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO RGD PMID:16133261 RGD:1581603 NCBI chr 2:1,675,323...1,989,110
Ensembl chr 2:1,675,360...1,989,111 		JBrowse link
G LOC100621006 RE1-silencing transcription factor-like involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:56,048,280...56,215,011
Ensembl chr 8:56,035,150...56,215,013 		JBrowse link
G MIDN midnolin acts_upstream_of_or_within ISO PMID:24187134 MGI PMID:24187134 RGD:8655525 NCBI chr 2:77,203,671...77,213,205
Ensembl chr 2:77,204,017...77,211,671 		JBrowse link
G MTNR1A melatonin receptor 1A ISO RGD PMID:22288848 RGD:9686057 NCBI chr17:8,597,047...8,618,746
Ensembl chr17:8,596,911...8,617,657 		JBrowse link
G MTNR1B melatonin receptor 1B ISO RGD PMID:18363673 RGD:9588673 NCBI chr 9:25,556,756...25,557,792
Ensembl chr 9:25,545,390...25,558,054 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:17130471 RGD:1642149 NCBI chr14:35,112,898...35,299,297
Ensembl chr14:35,113,184...35,295,944 		JBrowse link
G NPFF neuropeptide FF-amide peptide precursor ISO RGD PMID:1704109 RGD:2316580 NCBI chr 5:18,724,078...18,724,844
Ensembl chr 5:18,723,784...18,724,826 		JBrowse link
G PDE8B phosphodiesterase 8B ISO RGD PMID:17991719 RGD:2312519 NCBI chr 2:86,007,190...86,323,796
Ensembl chr 2:85,949,174...86,323,795 		JBrowse link
G PFKL phosphofructokinase, liver type involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:9287040) Ensembl
MGI		 PMID:9287040 GO_REF:0000107 NCBI chr13:207,167,287...207,191,688
Ensembl chr13:207,167,281...207,191,671 		JBrowse link
G PPP3CA protein phosphatase 3 catalytic subunit alpha involved_in ISO PMID:19965390 BHF-UCL PMID:19965390 RGD:2316628 NCBI chr 8:119,429,181...119,754,615
Ensembl chr 8:119,428,779...119,753,105 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase acts_upstream_of_or_within
involved_in		 ISO
IEA		 (PMID:24187134) MGI
Ensembl		 PMID:24187134 GO_REF:0000107 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872 		JBrowse link
G PSMD9 proteasome 26S subunit, non-ATPase 9 involved_in ISO PMID:16099819 BHF-UCL PMID:16099819 RGD:8554418 NCBI chr14:30,793,521...30,822,135
Ensembl chr14:30,793,524...30,822,127 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO RGD PMID:10531320 RGD:10043332 NCBI chr 6:141,958,955...142,160,437
Ensembl chr 6:141,958,955...142,161,286 		JBrowse link
G PTPN11 protein tyrosine phosphatase non-receptor type 11 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:15520383) Ensembl
MGI		 PMID:15520383 GO_REF:0000107 NCBI chr14:39,202,165...39,292,041
Ensembl chr14:39,202,169...39,292,003 		JBrowse link
G REST RE1 silencing transcription factor involved_in ISS UniProt GO_REF:0000024 NCBI chr 8:56,035,182...56,061,140
Ensembl chr 8:56,035,150...56,215,013 		JBrowse link
G RPTOR regulatory associated protein of MTOR complex 1 involved_in ISO (MGI:5619445|PMID:23092880) CACAO PMID:23092880 MGI:5619445 NCBI chr12:1,709,121...1,991,844
Ensembl chr12:1,709,128...1,991,574 		JBrowse link
G SFRP1 secreted frizzled related protein 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:10,436,414...10,489,773
Ensembl chr17:10,436,426...10,489,748 		JBrowse link
G SIRT4 sirtuin 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16959573) Ensembl
MGI		 PMID:16959573 GO_REF:0000107 NCBI chr14:40,290,288...40,303,887
Ensembl chr14:40,290,288...40,303,879 		JBrowse link
G SREBF1 sterol regulatory element binding transcription factor 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16890542) Ensembl
MGI		 PMID:16890542 GO_REF:0000107 NCBI chr12:60,733,967...60,750,951
Ensembl chr12:60,733,907...60,751,267 		JBrowse link
G STXBP5L syntaxin binding protein 5L involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:21998599) Ensembl
MGI		 PMID:21998599 GO_REF:0000107 NCBI chr13:139,116,931...139,491,227
Ensembl chr13:139,123,209...139,445,470 		JBrowse link
G SYTL4 synaptotagmin like 4 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16890542) Ensembl
MGI		 PMID:16890542 GO_REF:0000107 NCBI chr  X:82,367,546...82,437,439
Ensembl chr  X:82,367,549...82,437,401 		JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:17931748 RGD:2306798 NCBI chr 6:68,552,889...68,560,827
Ensembl chr 6:68,552,887...68,559,674 		JBrowse link
G VSNL1 visinin like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16731532) Ensembl
MGI		 PMID:16731532 GO_REF:0000107 NCBI chr 3:120,177,897...120,288,157
Ensembl chr 3:120,177,895...120,288,143 		JBrowse link
negative regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADRA2A adrenoceptor alpha 2A involved_in ISO (PMID:19965390) BHF-UCL PMID:19965390 RGD:2316628 NCBI chr14:121,469,572...121,470,924
Ensembl chr14:121,469,527...121,470,924 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 ISO RGD PMID:17360501 RGD:2306172 NCBI chr18:42,251,755...42,296,457
Ensembl chr18:42,251,749...42,295,467 		JBrowse link
G ENY2 ENY2 transcription and export complex 2 subunit ISO RGD PMID:22649445 RGD:9590329 NCBI chr 4:28,193,631...28,203,549
Ensembl chr 4:28,191,162...28,203,485 		JBrowse link
G FKBP1B FKBP prolyl isomerase 1B involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19805579) Ensembl
MGI		 PMID:19805579 GO_REF:0000107 NCBI chr 3:114,623,529...114,636,200
Ensembl chr 3:114,623,532...114,634,628 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:20610886 RGD:5508687 NCBI chr 2:84,380,245...84,401,117
Ensembl chr 2:84,380,224...84,402,957 		JBrowse link
G JAGN1 jagunal homolog 1 ISO RGD PMID:26882284 RGD:11520872 NCBI chr13:66,154,855...66,158,329 JBrowse link
G KLF7 KLF transcription factor 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:110,282,399...110,380,165
Ensembl chr15:110,286,463...110,379,305 		JBrowse link
G MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 ISO RGD PMID:19690174 RGD:7495848 NCBI chr 3:52,483,028...52,649,480
Ensembl chr 3:52,484,274...52,649,410 		JBrowse link
G NDUFAF2 NADH:ubiquinone oxidoreductase complex assembly factor 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22587331) Ensembl
MGI		 PMID:22587331 GO_REF:0000107 NCBI chr16:39,770,398...39,950,786
Ensembl chr16:39,770,466...39,950,785 		JBrowse link
G PDE1C phosphodiesterase 1C ISO RGD PMID:18706893 RGD:2302857 NCBI chr18:40,818,316...41,410,555
Ensembl chr18:40,820,644...41,409,087 		JBrowse link
G PDE3B phosphodiesterase 3B ISO RGD PMID:18706893 RGD:2302857 NCBI chr 2:44,416,934...44,614,075
Ensembl chr 2:44,412,833...44,726,216 		JBrowse link
G PDE4C phosphodiesterase 4C ISO RGD PMID:18706893 RGD:2302857 NCBI chr 2:59,567,644...59,598,398
Ensembl chr 2:59,578,261...59,598,396 		JBrowse link
G PDE8B phosphodiesterase 8B ISO RGD PMID:18706893 RGD:2302857 NCBI chr 2:86,007,190...86,323,796
Ensembl chr 2:85,949,174...86,323,795 		JBrowse link
G PIM3 Pim-3 proto-oncogene, serine/threonine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:677,705...680,690
Ensembl chr 5:677,705...680,695 		JBrowse link
G PTPMT1 protein tyrosine phosphatase mitochondrial 1 ISO RGD PMID:20167843 RGD:12904047 NCBI chr 2:15,044,432...15,052,815
Ensembl chr 2:15,043,613...15,052,831 		JBrowse link
G TBC1D1 TBC1 domain family member 1 ISO RGD PMID:28177704 RGD:150521607 NCBI chr 8:29,370,344...29,590,574
Ensembl chr 8:29,370,481...29,590,571 		JBrowse link
G UCP2 uncoupling protein 2 ISO RGD PMID:21172424 RGD:7204422 NCBI chr 9:8,358,559...8,364,552
Ensembl chr 9:8,358,025...8,365,547 		JBrowse link
positive regulation of insulin secretion term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AACS acetoacetyl-CoA synthetase involved_in ISO
IEA		 RGD
TreeGrafter		 PMID:17724028 GO_REF:0000118 RGD:2301019 NCBI chr14:28,109,845...28,169,261
Ensembl chr14:28,109,869...28,169,253 		JBrowse link
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:20695849 RGD:9588550 NCBI chr 3:33,913,068...33,960,804
Ensembl chr 3:33,908,970...34,015,474 		JBrowse link
G ACSL4 acyl-CoA synthetase long chain family member 4 involved_in ISO PMID:23766516 UniProt PMID:23766516 RGD:14695075 NCBI chr  X:89,760,863...89,838,103
Ensembl chr  X:89,760,866...89,806,274 		JBrowse link
G ADCY8 adenylate cyclase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:9,645,398...9,867,065
Ensembl chr 4:9,645,659...9,866,550 		JBrowse link
G ANXA7 annexin A7 acts_upstream_of_or_within_positive_effect ISO (PMID:10570150) MGI PMID:10570150 NCBI chr14:76,205,238...76,234,646
Ensembl chr14:76,205,232...76,234,631 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G BLK BLK proto-oncogene, Src family tyrosine kinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:14,688,489...14,745,946
Ensembl chr14:14,688,943...14,745,947 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C ISO RGD PMID:18562674 RGD:152177517 NCBI chr 5:69,016,954...69,448,428
Ensembl chr 5:69,275,176...69,448,430 		JBrowse link
G CAPN10 calpain 10 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:139,557,643...139,568,764
Ensembl chr15:139,557,469...139,568,767 		JBrowse link
G CASK calcium/calmodulin dependent serine protein kinase ISO RGD PMID:24140090 RGD:11576293 NCBI chr  X:37,166,973...37,535,723
Ensembl chr  X:37,167,577...37,536,160 		JBrowse link
G CASR calcium sensing receptor ISO RGD PMID:22566534 RGD:7205453 NCBI chr13:138,279,785...138,364,934
Ensembl chr13:138,280,364...138,364,252 		JBrowse link
G CD38 CD38 molecule ISO RGD PMID:9664081 RGD:2307276 NCBI chr 8:11,083,682...11,130,783
Ensembl chr 8:11,083,682...11,130,756 		JBrowse link
G CHRM3 cholinergic receptor muscarinic 3 involved_in ISO (PMID:16753580)
(PMID:20440069)		 MGI PMID:16753580 PMID:20440069 NCBI chr14:51,818,625...52,363,662
Ensembl chr14:51,828,231...51,830,003 		JBrowse link
G DOC2B double C2 domain beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,529,383...47,558,236
Ensembl chr12:47,529,367...47,562,373 		JBrowse link
G F2 coagulation factor II, thrombin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:15,793,257...15,819,151
Ensembl chr 2:15,791,455...15,819,137 		JBrowse link
G F2RL2 coagulation factor II thrombin receptor like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:85,534,188...85,542,062
Ensembl chr 2:85,535,676...85,541,767 		JBrowse link
G FFAR1 free fatty acid receptor 1 involved_in IEA TreeGrafter GO_REF:0000118 NCBI chr 6:44,837,764...44,841,518 JBrowse link
G FFAR2 free fatty acid receptor 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 6:44,899,879...44,904,461
Ensembl chr 6:44,901,159...44,904,459 		JBrowse link
G GCK glucokinase involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:50,979,167...51,024,500
Ensembl chr18:50,979,167...51,029,844 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide involved_in ISS
IEA		 UniProt GO_REF:0000024 GO_REF:0000104 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G GIP gastric inhibitory polypeptide involved_in ISO
IEA		 RGD
Ensembl		 PMID:8958204 GO_REF:0000107 RGD:2312537 NCBI chr12:25,160,783...25,167,952
Ensembl chr12:25,160,789...25,167,940 		JBrowse link
G GIPR gastric inhibitory polypeptide receptor involved_in ISO
IEA		 RGD
Ensembl		 PMID:11014226 GO_REF:0000107 RGD:2312607 NCBI chr 6:52,022,667...52,033,959
Ensembl chr 6:52,022,681...52,033,954 		JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:24301293 RGD:8662441 NCBI chr 1:40,988,818...41,002,129
Ensembl chr 1:40,988,528...41,002,156 		JBrowse link
G GLP1R glucagon like peptide 1 receptor ISO RGD PMID:12093887 RGD:625448 NCBI chr 7:34,497,779...34,534,356
Ensembl chr 7:34,497,759...34,534,627 		JBrowse link
G GLRX glutaredoxin ISO RGD PMID:19299446 RGD:9686053 NCBI chr 2:102,425,580...102,437,851
Ensembl chr 2:102,425,580...102,437,858 		JBrowse link
G GLUD1 glutamate dehydrogenase 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16959573) Ensembl
MGI		 PMID:16959573 GO_REF:0000107 NCBI chr14:87,968,850...88,005,375
Ensembl chr14:87,968,850...88,005,520 		JBrowse link
G GLUL glutamate-ammonia ligase ISO ornithine alpha-ketoglutarate-induced secretion RGD PMID:12575909 RGD:2301557 NCBI chr 9:123,751,551...123,762,575
Ensembl chr 9:123,748,380...123,762,545 		JBrowse link
G GNA11 G protein subunit alpha 11 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:75,439,405...75,456,855
Ensembl chr 2:75,437,201...75,457,092 		JBrowse link
G GNAQ G protein subunit alpha q involved_in ISO (PMID:20440069)
(PMID:26075576)		 MGI PMID:20440069 PMID:26075576 NCBI chr 1:230,607,469...230,906,988
Ensembl chr 1:230,605,265...230,907,674 		JBrowse link
G GNAS GNAS complex locus involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:58,985,580...59,053,022
Ensembl chr17:58,998,981...59,053,021 		JBrowse link
G GPER1 G protein-coupled estrogen receptor 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:711,427...715,982
Ensembl chr 3:712,160...715,980 		JBrowse link
G GPR39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (PMID:19213841) MGI PMID:19213841 NCBI chr15:19,556,066...19,801,203
Ensembl chr15:19,557,893...19,799,040 		JBrowse link
G GPR68 G protein-coupled receptor 68 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22733973) Ensembl
MGI		 PMID:22733973 GO_REF:0000107 NCBI chr 7:112,885,160...112,904,214
Ensembl chr 7:112,885,163...112,904,246 		JBrowse link
G HNF1A HNF1 homeobox A ISO RGD PMID:10944108 RGD:150540301 NCBI chr14:40,868,819...40,888,322
Ensembl chr14:40,868,676...40,888,328 		JBrowse link
G IRS2 insulin receptor substrate 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr11:76,626,158...76,654,639
Ensembl chr11:76,626,179...76,653,881 		JBrowse link
G ISL1 ISL LIM homeobox 1 involved_in IEA
ISO		 Ensembl
RGD		 PMID:11978636 PMID:29678908 GO_REF:0000107 RGD:243065231 RGD:729103 NCBI chr16:30,962,994...30,974,201
Ensembl chr16:30,963,000...30,973,907 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:61,068,131...61,398,918
Ensembl chr13:61,068,126...61,398,912 		JBrowse link
G JAK2 Janus kinase 2 ISO in response to human growth hormone RGD PMID:16597920 RGD:1641815 NCBI chr 1:216,849,744...217,002,310
Ensembl chr 1:216,848,689...217,002,148 		JBrowse link
G LRRC8A leucine rich repeat containing 8 VRAC subunit A involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:269,209,660...269,238,529
Ensembl chr 1:269,209,693...269,238,521 		JBrowse link
G MCU mitochondrial calcium uniporter involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:75,518,533...75,721,502
Ensembl chr14:75,678,393...75,721,500 		JBrowse link
G MYL7 myosin light chain 7 involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:51,026,436...51,028,917
Ensembl chr18:50,979,167...51,029,844 		JBrowse link
G MYRIP myosin VIIA and Rab interacting protein involved_in ISO PMID:17827149 UniProt PMID:17827149 RGD:8554303 NCBI chr13:24,347,574...24,556,743
Ensembl chr13:24,347,660...24,556,735 		JBrowse link
G NKX6-1 NK6 homeobox 1 ISO RGD PMID:15883383 RGD:2306242 NCBI chr 8:134,137,064...134,143,524
Ensembl chr 8:134,138,097...134,144,254 		JBrowse link
G NNAT neuronatin involved_in
acts_upstream_of_or_within		 IBA
ISO
IEA		 (PMID:15793245) GO_Central
MGI
TreeGrafter		 PMID:15793245 GO_REF:0000033 GO_REF:0000118 NCBI chr17:40,625,990...40,629,523 JBrowse link
G NR0B2 nuclear receptor subfamily 0 group B member 2 ISO RGD PMID:17259388 RGD:2311606 NCBI chr 6:84,225,670...84,228,156
Ensembl chr 6:84,225,694...84,228,481 		JBrowse link
G OGA O-GlcNAcase ISO RGD PMID:17095531 RGD:2305956 NCBI chr14:112,822,494...112,851,215
Ensembl chr14:112,822,499...112,851,203 		JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:31,012,212...31,028,008
Ensembl chr14:31,011,644...31,027,993 		JBrowse link
G PCK2 phosphoenolpyruvate carboxykinase 2, mitochondrial ISO RGD PMID:19635791 RGD:7242950 NCBI chr 7:75,187,195...75,197,613
Ensembl chr 7:75,187,197...75,197,733 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 involved_in ISO
IEA		 RGD
Ensembl		 PMID:18439098 GO_REF:0000107 RGD:2306975 NCBI chr11:5,303,609...5,309,063
Ensembl chr11:5,303,609...5,309,063 		JBrowse link
G PFKFB2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2 ISO RGD PMID:16980436 RGD:2304071 NCBI chr 9:67,681,786...67,716,921
Ensembl chr 9:67,681,953...67,709,516 		JBrowse link
G PFKM phosphofructokinase, muscle involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:17595219) Ensembl
MGI		 PMID:17595219 GO_REF:0000107 NCBI chr 5:78,475,473...78,525,052
Ensembl chr 5:78,476,123...78,526,997 		JBrowse link
G PLCB1 phospholipase C beta 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr17:17,007,197...17,745,314
Ensembl chr17:17,007,261...17,745,313 		JBrowse link
G PRKACA protein kinase cAMP-activated catalytic subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:65,074,876...65,095,564
Ensembl chr 2:65,074,870...65,095,551 		JBrowse link
G PRKAR1A protein kinase cAMP-dependent type I regulatory subunit alpha involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:11,662,344...11,681,490
Ensembl chr12:11,662,347...11,681,373 		JBrowse link
G PRKCB protein kinase C beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:21,995,227...22,383,628
Ensembl chr 3:21,995,231...22,383,264 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12837755) Ensembl
MGI		 PMID:12837755 GO_REF:0000107 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,866,306 		JBrowse link
G PSMD9 proteasome 26S subunit, non-ATPase 9 involved_in ISO PMID:10567574 BHF-UCL PMID:10567574 RGD:633869 NCBI chr14:30,793,521...30,822,135
Ensembl chr14:30,793,524...30,822,127 		JBrowse link
G PTBP1 polypyrimidine tract binding protein 1 ISO RGD PMID:15039777 RGD:10045958 NCBI chr 2:77,551,562...77,563,153
Ensembl chr 2:77,551,562...77,563,134 		JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:78,773,270...79,094,490
Ensembl chr15:78,773,266...79,095,040 		JBrowse link
G RBP4 retinol binding protein 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:105,037,360...105,044,552
Ensembl chr14:105,037,464...105,044,765 		JBrowse link
G RPH3AL rabphilin 3A like (without C2 domains) involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:47,322,505...47,497,904
Ensembl chr12:47,388,582...47,497,902 		JBrowse link
G SERP1 stress associated endoplasmic reticulum protein 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16415102) Ensembl
MGI		 PMID:16415102 GO_REF:0000107 NCBI chr13:90,756,845...90,761,400
Ensembl chr13:90,756,855...90,761,560 		JBrowse link
G SIRT3 sirtuin 3 ISO RGD PMID:23397292 RGD:9586042 NCBI chr 2:38,465...55,074
Ensembl chr 2:38,464...55,101 		JBrowse link
G SIRT6 sirtuin 6 involved_in ISO (MGI:6101624|PMID:27457971) UniProt PMID:27457971 MGI:6101624 NCBI chr 2:74,568,539...74,577,774
Ensembl chr 2:74,568,493...74,577,772 		JBrowse link
G SLC30A8 solute carrier family 30 member 8 involved_in ISO PMID:19479076 BHF-UCL PMID:19479076 RGD:2315022 NCBI chr 4:21,517,009...21,557,747
Ensembl chr 4:21,517,486...21,555,746 		JBrowse link
G SNAP25 synaptosome associated protein 25 ISO RGD PMID:15042624 RGD:1581081 NCBI chr17:19,096,115...19,227,580
Ensembl chr17:19,141,464...19,227,576 		JBrowse link
G SOX4 SRY-box transcription factor 4 involved_in ISS
IEA		 UniProt
Ensembl		 GO_REF:0000024 GO_REF:0000107 NCBI chr 7:16,886,834...16,895,488
Ensembl chr 7:16,891,319...16,892,752 		JBrowse link
G STIM1 stromal interaction molecule 1 involved_in ISO (PMID:18452988)
(PMID:30131394), (PMID:31664108)
(PMID:31664108)		 MGI PMID:18452988 PMID:30131394 PMID:31664108 NCBI chr 9:6,066,612...6,270,090
Ensembl chr 9:6,066,617...6,270,575 		JBrowse link
G TARDBP TAR DNA binding protein ISO RGD PMID:21127054 RGD:7243008 NCBI chr 6:71,213,584...71,227,707
Ensembl chr 6:71,213,860...71,227,704 		JBrowse link
G TCF7L2 transcription factor 7 like 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,412...123,546,417 		JBrowse link
G TM7SF3 transmembrane 7 superfamily member 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:46,740,936...46,784,195
Ensembl chr 5:46,740,949...46,784,194 		JBrowse link
G TRH thyrotropin releasing hormone involved_in ISO
IEA
IBA		 RGD
TreeGrafter
GO_Central		 PMID:16118471 GO_REF:0000033 GO_REF:0000118 RGD:1600419 NCBI chr13:69,362,892...69,366,183
Ensembl chr13:69,364,093...69,365,493 		JBrowse link
G TRPM2 transient receptor potential cation channel subfamily M member 2 ISO RGD PMID:16601673 RGD:9999436 NCBI chr13:207,212,339...207,263,313
Ensembl chr13:207,212,457...207,262,064 		JBrowse link
G UCN3 urocortin 3 ISO RGD PMID:17360501 RGD:2306172 NCBI chr10:65,491,231...65,495,879 JBrowse link
positive regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCC8 ATP binding cassette subfamily C member 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:41,666,974...41,754,624
Ensembl chr 2:41,666,909...41,754,620 		JBrowse link
G ABCG1 ATP binding cassette subfamily G member 1 ISO RGD PMID:29540530 RGD:41404656 NCBI chr13:205,561,897...205,628,428
Ensembl chr13:205,561,951...205,628,425 		JBrowse link
G ADCY8 adenylate cyclase 8 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 4:9,645,398...9,867,065
Ensembl chr 4:9,645,659...9,866,550 		JBrowse link
G ANO1 anoctamin 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:3,202,269...3,373,409
Ensembl chr 2:3,202,166...3,373,411 		JBrowse link
G ARRB1 arrestin beta 1 involved_in ISO (MGI:4453294|PMID:19915011) UniProt PMID:19915011 MGI:4453294 NCBI chr 9:9,516,944...9,597,446
Ensembl chr 9:9,516,947...9,597,976 		JBrowse link
G ATG7 autophagy related 7 acts_upstream_of_or_within ISO (PMID:24105478) MGI PMID:24105478 NCBI chr13:67,301,756...67,699,141
Ensembl chr13:67,417,938...67,707,654 		JBrowse link
G BAD BCL2 associated agonist of cell death involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:7,831,192...7,842,864
Ensembl chr 2:7,830,920...7,842,863 		JBrowse link
G BAIAP3 BAI1 associated protein 3 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:40,536,557...40,550,508
Ensembl chr 3:40,537,399...40,550,471 		JBrowse link
G C1QTNF12 C1q and TNF related 12 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22275362) Ensembl
MGI		 PMID:22275362 GO_REF:0000107 NCBI chr 6:63,548,862...63,555,991
Ensembl chr 6:63,548,864...63,553,332 		JBrowse link
G C2CD2L C2CD2 like involved_in
acts_upstream_of_or_within		 IEA
ISO
IBA		 (PMID:24012759) Ensembl
MGI
GO_Central
TreeGrafter		 PMID:24012759 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr 9:46,321,761...46,331,078
Ensembl chr 9:46,321,817...46,331,078 		JBrowse link
G CACNA1D calcium voltage-gated channel subunit alpha1 D ISO RGD PMID:23229155 RGD:13506727 NCBI chr13:35,568,534...35,911,483
Ensembl chr13:35,436,519...35,909,662 		JBrowse link
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 ISO RGD PMID:31327268 RGD:18899561 NCBI chr 6:78,730,204...78,734,232
Ensembl chr 6:78,730,206...78,733,740 		JBrowse link
G CFTR CF transmembrane conductance regulator involved_in IEA Ensembl GO_REF:0000107 NCBI chr18:28,627,717...28,818,209
Ensembl chr18:28,627,728...28,817,950 		JBrowse link
G CRH corticotropin releasing hormone ISO RGD PMID:20080775 RGD:5508172 NCBI chr 4:68,481,696...68,486,122
Ensembl chr 4:68,484,053...68,486,121 		JBrowse link
G DYNLL1 dynein light chain LC8-type 1 ISO RGD PMID:17130471 RGD:1642149 NCBI chr14:40,455,954...40,458,352
Ensembl chr14:40,455,985...40,459,104 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase ISO RGD PMID:29890211 RGD:329951007 NCBI chr 6:31,177,112...31,564,674
Ensembl chr 6:31,174,569...31,564,718 		JBrowse link
G GCG glucagon involved_in IBA GO_Central GO_REF:0000033 NCBI chr15:68,800,557...68,810,268
Ensembl chr15:68,800,560...68,810,242 		JBrowse link
G GHRL ghrelin and obestatin prepropeptide ISO RGD PMID:16647196 RGD:12905046 NCBI chr13:66,442,106...66,453,576
Ensembl chr13:66,445,992...66,452,917 		JBrowse link
G GPLD1 glycosylphosphatidylinositol specific phospholipase D1 involved_in ISO (MGI:5448527|PMID:20153004) UniProt PMID:20153004 MGI:5448527 NCBI chr 7:19,289,385...19,355,606
Ensembl chr 7:19,291,174...19,346,619 		JBrowse link
G GPR27 G protein-coupled receptor 27 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22253604) Ensembl
MGI		 PMID:22253604 GO_REF:0000107 NCBI chr13:53,152,038...53,154,537
Ensembl chr13:53,152,062...53,153,192 		JBrowse link
G GPR39 G protein-coupled receptor 39 acts_upstream_of_or_within ISO (PMID:19213833) MGI PMID:19213833 NCBI chr15:19,556,066...19,801,203
Ensembl chr15:19,557,893...19,799,040 		JBrowse link
G GPR68 G protein-coupled receptor 68 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22733973) Ensembl
MGI		 PMID:22733973 GO_REF:0000107 NCBI chr 7:112,885,160...112,904,214
Ensembl chr 7:112,885,163...112,904,246 		JBrowse link
G HCFC1 host cell factor C1 involved_in ISO PMID:24250814 UniProt PMID:24250814 RGD:151356618 NCBI chr  X:124,673,125...124,694,846
Ensembl chr  X:124,673,128...124,694,152 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:20440072) Ensembl
MGI		 PMID:20440072 GO_REF:0000107 NCBI chr 1:190,625,436...190,673,926
Ensembl chr 1:190,625,244...190,674,845 		JBrowse link
G KIF5B kinesin family member 5B ISO RGD PMID:25462067 RGD:11059539 NCBI chr10:42,637,105...42,693,551
Ensembl chr10:42,637,109...42,693,491 		JBrowse link
G LEPR leptin receptor ISO RGD PMID:9751766 RGD:10412039 NCBI chr 6:146,802,297...146,896,152
Ensembl chr 6:146,801,954...146,895,995 		JBrowse link
G LRP1 LDL receptor related protein 1 ISO RGD PMID:24865476 RGD:13800516 NCBI chr 5:22,435,636...22,519,276 JBrowse link
G MPC2 mitochondrial pyruvate carrier 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:24910426) Ensembl
MGI		 PMID:24910426 GO_REF:0000107 NCBI chr 4:83,069,914...83,091,687
Ensembl chr 4:83,069,748...83,096,990 		JBrowse link
G MYH9 myosin heavy chain 9 ISO RGD PMID:23354122 RGD:12798521 NCBI chr 5:11,365,603...11,456,475
Ensembl chr 5:11,360,660...11,456,472 		JBrowse link
G NADK NAD kinase ISO RGD PMID:22550069 RGD:13703105 NCBI chr 6:63,846,650...63,864,137
Ensembl chr 6:63,846,655...63,863,946 		JBrowse link
G NCOA6 nuclear receptor coactivator 6 ISO RGD PMID:16738321 RGD:9590126 NCBI chr17:38,114,284...38,221,904
Ensembl chr17:38,114,291...38,221,901 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,294...83,684,604 		JBrowse link
G OSBP oxysterol binding protein ISO RGD PMID:29540530 RGD:41404656 NCBI chr 2:11,876,294...11,911,660
Ensembl chr 2:11,876,324...11,911,656 		JBrowse link
G OXCT1 3-oxoacid CoA-transferase 1 ISO RGD PMID:20460097 RGD:2326185 NCBI chr16:26,514,497...26,659,739
Ensembl chr16:26,512,401...26,659,808 		JBrowse link
G PDX1 pancreatic and duodenal homeobox 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:22253604) Ensembl
MGI		 PMID:22253604 GO_REF:0000107 NCBI chr11:5,303,609...5,309,063
Ensembl chr11:5,303,609...5,309,063 		JBrowse link
G PLA2G6 phospholipase A2 group VI involved_in ISO
IEA		 RGD
Ensembl		 PMID:11278673 GO_REF:0000107 RGD:6482760 NCBI chr 5:9,713,809...9,777,921
Ensembl chr 5:9,713,873...9,777,918 		JBrowse link
G PPARD peroxisome proliferator activated receptor delta ISO RGD PMID:19965574 RGD:2324877 NCBI chr 7:31,222,533...31,295,221
Ensembl chr 7:31,222,585...31,295,211 		JBrowse link
G PPP3CB protein phosphatase 3 catalytic subunit beta involved_in IEA Ensembl GO_REF:0000107 NCBI chr14:76,239,497...76,305,345
Ensembl chr14:76,248,841...76,305,328 		JBrowse link
G PRKN parkin RBR E3 ubiquitin protein ligase ISO RGD PMID:24096089 RGD:10413842 NCBI chr 1:5,698,508...6,731,132
Ensembl chr 1:5,465,312...6,730,872 		JBrowse link
G RAC1 Rac family small GTPase 1 involved_in ISO (MGI:5489045|PMID:23412604) RGD
CACAO		 PMID:23412604 MGI:5489045 RGD:14392803 NCBI chr 3:4,781,776...4,803,510
Ensembl chr 3:4,781,780...4,803,543 		JBrowse link
G RFX6 regulatory factor X6 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 1:44,765,451...44,826,884
Ensembl chr 1:44,765,451...44,823,510 		JBrowse link
G SIRT1 sirtuin 1 ISO RGD PMID:16366736 RGD:9585658 NCBI chr14:71,091,167...71,126,351
Ensembl chr14:71,091,167...71,123,297 		JBrowse link
G SLC2A2 solute carrier family 2 member 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:109,592,595...109,614,105
Ensembl chr13:109,587,258...109,638,510 		JBrowse link
G SRI sorcin involved_in IEA Ensembl GO_REF:0000107 NCBI chr 9:68,492,235...68,515,247
Ensembl chr 9:68,490,890...68,515,322 		JBrowse link
G STX4 syntaxin 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 3:17,422,266...17,431,377
Ensembl chr 3:17,416,842...17,431,053 		JBrowse link
G SYBU syntabulin ISO RGD PMID:22975310 RGD:8554225 NCBI chr 4:27,899,264...27,975,389
Ensembl chr 4:27,901,097...27,974,660 		JBrowse link
G TRPA1 transient receptor potential cation channel subfamily A member 1 ISO RGD PMID:22701540 RGD:10043784 NCBI chr 4:63,493,374...63,558,486
Ensembl chr 4:63,508,104...63,558,484 		JBrowse link
G TRPM4 transient receptor potential cation channel subfamily M member 4 ISO RGD PMID:16806463 RGD:10003029 NCBI chr 6:54,342,774...54,377,557
Ensembl chr 6:54,342,784...54,377,155 		JBrowse link
G TUNAR TCL1 upstream neural differentiation-associated RNA involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 7:117,083,580...117,136,145 JBrowse link
G VSNL1 visinin like 1 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:16731532) Ensembl
MGI		 PMID:16731532 GO_REF:0000107 NCBI chr 3:120,177,897...120,288,157
Ensembl chr 3:120,177,895...120,288,143 		JBrowse link
regulation of insulin secretion involved in cellular response to glucose stimulus term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA12 ATP binding cassette subfamily A member 12 involved_in IEA Ensembl GO_REF:0000107 NCBI chr15:117,244,704...117,451,009
Ensembl chr15:117,244,719...117,450,863 		JBrowse link
G ADCY5 adenylate cyclase 5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr13:136,965,746...137,133,795
Ensembl chr13:136,972,801...137,135,347 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 acts_upstream_of_or_within ISO (PMID:19644667) MGI PMID:19644667 NCBI chr12:3,747,276...3,755,214
Ensembl chr12:3,747,279...3,755,215 		JBrowse link
G BRSK2 BR serine/threonine kinase 2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:896,720...953,908
Ensembl chr 2:896,585...953,108 		JBrowse link
G CACNA1E calcium voltage-gated channel subunit alpha1 E acts_upstream_of_or_within ISO (PMID:11923483), (PMID:15630454) MGI PMID:11923483 PMID:15630454 NCBI chr 9:122,827,386...123,318,372
Ensembl chr 9:123,006,195...123,315,319 		JBrowse link
G CDK16 cyclin dependent kinase 16 involved_in IEA Ensembl GO_REF:0000107 NCBI chr  X:41,836,268...41,848,580
Ensembl chr  X:41,835,987...41,848,574 		JBrowse link
G DDRGK1 DDRGK domain containing 1 NOT|involved_in ISO PMID:21494687 ParkinsonsUK-UCL PMID:21494687 RGD:11567254 NCBI chr17:32,479,981...32,491,401
Ensembl chr17:32,479,977...32,491,396 		JBrowse link
G EFNA5 ephrin A5 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 2:112,533,124...112,821,293
Ensembl chr 2:112,534,949...112,815,827 		JBrowse link
G EPHA5 EPH receptor A5 involved_in ISO (MGI:5294297|PMID:17448994) UniProt PMID:17448994 MGI:5294297 NCBI chr 8:63,285,006...63,604,734
Ensembl chr 8:63,287,711...63,604,734 		JBrowse link
G FOXA2 forkhead box A2 involved_in ISO (MGI:5142372|PMID:11875061) BHF-UCL PMID:11875061 MGI:5142372 NCBI chr17:29,997,397...30,001,704
Ensembl chr17:29,997,401...30,001,707 		JBrowse link
G HMGN3 high mobility group nucleosomal binding domain 3 acts_upstream_of_or_within ISO (PMID:19651901) MGI PMID:19651901 NCBI chr 1:86,954,468...86,987,465
Ensembl chr 1:86,954,465...86,987,460 		JBrowse link
G LRP5 LDL receptor related protein 5 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:12509515) Ensembl
MGI
TreeGrafter		 PMID:12509515 GO_REF:0000107 GO_REF:0000118 NCBI chr 2:4,533,721...4,653,997
Ensembl chr 2:4,533,614...4,653,944 		JBrowse link
G MIR130A microRNA mir-130a acts_upstream_of_or_within ISO (PMID:20417623) MGI PMID:20417623 NCBI chr 2:13,296,695...13,296,773
Ensembl chr 2:13,296,695...13,296,773 		JBrowse link
G MYT1 myelin transcription factor 1 acts_upstream_of_or_within ISO (PMID:17928203) MGI PMID:17928203 NCBI chr17:62,955,052...63,020,652
Ensembl chr17:62,979,350...63,014,696 		JBrowse link
G NR1D1 nuclear receptor subfamily 1 group D member 1 involved_in IEA Ensembl GO_REF:0000107 NCBI chr12:22,263,549...22,274,131
Ensembl chr12:22,263,657...22,271,643 		JBrowse link
G NR1H4 nuclear receptor subfamily 1 group H member 4 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 5:83,607,222...83,732,668
Ensembl chr 5:83,604,294...83,684,604 		JBrowse link
G PIWIL4 piwi like RNA-mediated gene silencing 4 involved_in ISO PMID:28711973 UniProt PMID:28711973 RGD:13800537 NCBI chr 9:26,679,960...26,751,856
Ensembl chr 9:26,703,340...26,751,854 		JBrowse link
G PRKCE protein kinase C epsilon involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:19401415) Ensembl
MGI		 PMID:19401415 GO_REF:0000107 NCBI chr 3:94,351,277...94,864,549
Ensembl chr 3:94,349,889...94,866,306 		JBrowse link
G SIDT2 SID1 transmembrane family member 2 involved_in
acts_upstream_of_or_within		 IEA
ISO		 (PMID:23776622) Ensembl
MGI		 PMID:23776622 GO_REF:0000107 NCBI chr 9:44,543,648...44,559,717
Ensembl chr 9:44,543,701...44,559,715 		JBrowse link
G SLC9B2 solute carrier family 9 member B2 involved_in IEA Ensembl GO_REF:0000107 NCBI chr 8:117,996,777...118,049,430
Ensembl chr 8:117,997,128...118,046,506 		JBrowse link
G STXBP4 syntaxin binding protein 4 involved_in IEA
IBA		 Ensembl
TreeGrafter
GO_Central		 GO_REF:0000033 GO_REF:0000107 GO_REF:0000118 NCBI chr12:31,277,116...31,478,828
Ensembl chr12:31,277,487...31,472,792 		JBrowse link
G SYBU syntabulin acts_upstream_of_or_within ISO PMID:22975310 MGI PMID:22975310 RGD:8554225 NCBI chr 4:27,899,264...27,975,389
Ensembl chr 4:27,901,097...27,974,660 		JBrowse link
G TCF7L2 transcription factor 7 like 2 acts_upstream_of_or_within ISO (PMID:19168596) MGI PMID:19168596 NCBI chr14:123,343,695...123,547,332
Ensembl chr14:123,343,412...123,546,417 		JBrowse link
G TIAM1 TIAM Rac1 associated GEF 1 ISO RGD PMID:18930714 RGD:10043296 NCBI chr13:194,774,495...195,235,750
Ensembl chr13:194,774,497...195,005,089 		JBrowse link
G UFM1 ubiquitin fold modifier 1 NOT|involved_in ISO PMID:21494687 ParkinsonsUK-UCL PMID:21494687 RGD:11567254 NCBI chr11:13,516,814...13,779,446
Ensembl chr11:13,765,497...13,774,294 		JBrowse link
G ZBED6 zinc finger, BED-type containing 6 involved_in IEA Ensembl GO_REF:0000107 Ensembl chr 9:64,520,950...64,524,501 JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17806
    regulation of biological process 12538
      regulation of signaling 3672
        regulation of hormone secretion 355
          regulation of peptide hormone secretion 278
            regulation of insulin secretion 225
              negative regulation of insulin secretion + 61
              positive regulation of insulin secretion + 118
              regulation of insulin secretion involved in cellular response to glucose stimulus + 91
Path 2
Term Annotations click to browse term
  biological_process 17806
    localization 5407
      establishment of localization 4711
        transport 4404
          secretion 1144
            secretion by cell 986
              signal release 639
                hormone secretion 419
                  peptide hormone secretion 332
                    insulin secretion 266
                      regulation of insulin secretion 225
                        negative regulation of insulin secretion + 61
                        positive regulation of insulin secretion + 118
                        regulation of insulin secretion involved in cellular response to glucose stimulus + 91
paths to the root