ENY2 (ENY2 transcription and export complex 2 subunit) - Rat Genome Database

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Gene: ENY2 (ENY2 transcription and export complex 2 subunit) Sus scrofa
Analyze
Symbol: ENY2
Name: ENY2 transcription and export complex 2 subunit
RGD ID: 14220714
Description: ENCODES a protein that exhibits chromatin binding (inferred); nuclear receptor coactivator activity (inferred); transcription coactivator activity (inferred); INVOLVED IN negative regulation of insulin secretion involved in cellular response to glucose stimulus (ortholog); PARTICIPATES IN RNA polymerase II transcription initiation pathway; ASSOCIATED WITH genetic disease (ortholog); FOUND IN DUBm complex (inferred); mitochondrion (inferred); nuclear pore (inferred)
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: enhancer of yellow 2 homolog; enhancer of yellow 2 transcription factor homolog; transcription and mRNA export factor ENY2
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl428,191,162 - 28,203,485 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1428,193,631 - 28,203,549 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2430,510,007 - 30,519,933 (-)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References
Additional References at PubMed
PMID:14681463   PMID:17145712   PMID:17407547   PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
ENY2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl428,191,162 - 28,203,485 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1428,193,631 - 28,203,549 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2430,510,007 - 30,519,933 (-)NCBISscrofa10.2Sscrofa10.2susScr3
ENY2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh388109,334,347 - 109,345,954 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl8109,334,324 - 109,345,954 (+)EnsemblGRCh38hg38GRCh38
GRCh378110,346,576 - 110,358,183 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 368110,415,812 - 110,425,087 (+)NCBINCBI36Build 36hg18NCBI36
Celera8106,534,242 - 106,545,876 (+)NCBICelera
Cytogenetic Map8q23.1NCBI
HuRef8105,668,557 - 105,680,193 (+)NCBIHuRef
CHM1_18110,386,800 - 110,398,436 (+)NCBICHM1_1
T2T-CHM13v2.08110,462,889 - 110,474,496 (+)NCBIT2T-CHM13v2.0
Eny2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391544,291,488 - 44,301,652 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1544,291,438 - 44,301,652 (+)EnsemblGRCm39 Ensembl
GRCm381544,428,082 - 44,438,256 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1544,428,042 - 44,438,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv371544,259,657 - 44,269,231 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361544,258,185 - 44,267,759 (+)NCBIMGSCv36mm8
Celera1544,891,120 - 44,900,693 (+)NCBICelera
Cytogenetic Map15B3.2NCBI
cM Map1516.91NCBI
Eny2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8777,465,885 - 77,489,637 (+)NCBIGRCr8
mRatBN7.2775,581,215 - 75,605,903 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl775,581,240 - 75,605,897 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx777,440,783 - 77,449,581 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0779,643,274 - 79,652,072 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0779,520,753 - 79,529,553 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0783,348,656 - 83,358,430 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl783,348,694 - 83,357,492 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0783,362,762 - 83,372,537 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4780,299,884 - 80,308,682 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera772,580,226 - 72,588,708 (+)NCBICelera
Cytogenetic Map7q31NCBI
Eny2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541716,750,579 - 16,760,839 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495541716,750,563 - 16,760,839 (+)NCBIChiLan1.0ChiLan1.0
ENY2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v27126,710,882 - 126,720,467 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan18102,232,070 - 102,241,433 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v08105,985,043 - 105,996,686 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.18108,129,872 - 108,141,478 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl8108,129,883 - 108,141,478 (+)Ensemblpanpan1.1panPan2
ENY2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1139,895,537 - 9,905,081 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl139,895,630 - 9,905,301 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha139,885,736 - 9,896,008 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01310,176,650 - 10,186,922 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1310,177,476 - 10,187,142 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1139,918,232 - 9,928,506 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01310,035,178 - 10,045,448 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01310,124,742 - 10,135,020 (+)NCBIUU_Cfam_GSD_1.0
Eny2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440530328,208,553 - 28,223,649 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493647035,639,024 - 35,649,725 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493647035,634,650 - 35,649,683 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ENY2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.18104,044,671 - 104,054,272 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl8104,044,634 - 104,056,953 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603936,519,384 - 36,531,309 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eny2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247638,423,730 - 8,433,772 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247638,423,647 - 8,433,772 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in ENY2
96 total Variants

Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 10 1 3 4 2 22 2 3 1
Low 3 1 1 2
Below cutoff

Sequence


RefSeq Acc Id: ENSSSCT00000045664   ⟹   ENSSSCP00000031993
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl428,191,162 - 28,203,485 (-)Ensembl
RefSeq Acc Id: ENSSSCT00000095180   ⟹   ENSSSCP00000075489
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl428,191,162 - 28,202,474 (-)Ensembl
RefSeq Acc Id: NM_001243453   ⟹   NP_001230382
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1428,193,631 - 28,203,536 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001243454   ⟹   NP_001230383
RefSeq Status: VALIDATED
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1428,193,631 - 28,203,536 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005655342   ⟹   XP_005655399
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1428,193,634 - 28,203,549 (-)NCBI
Sequence:
RefSeq Acc Id: NP_001230383   ⟸   NM_001243454
- Peptide Label: isoform 2
- UniProtKB: A0A4X1U732 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230382   ⟸   NM_001243453
- Peptide Label: isoform 1
- UniProtKB: A0A286ZK95 (UniProtKB/TrEMBL),   A0A4X1TFA2 (UniProtKB/TrEMBL),   A0A4X1U732 (UniProtKB/TrEMBL),   A0A8D0Z7Z1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_005655399   ⟸   XM_005655342
- Peptide Label: isoform X1
- UniProtKB: A0A8D1S712 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSSSCP00000031993   ⟸   ENSSSCT00000045664
RefSeq Acc Id: ENSSSCP00000075489   ⟸   ENSSSCT00000095180


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000038444 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00005015486 UniProtKB/TrEMBL
  ENSSSCG00015034634 UniProtKB/TrEMBL
  ENSSSCG00025054580 UniProtKB/TrEMBL
  ENSSSCG00030005499 UniProtKB/TrEMBL
  ENSSSCG00035024393 UniProtKB/TrEMBL
  ENSSSCG00040020529 UniProtKB/TrEMBL
  ENSSSCG00045001340 UniProtKB/TrEMBL
  ENSSSCG00050013799 UniProtKB/TrEMBL
  ENSSSCG00055030386 UniProtKB/TrEMBL
  ENSSSCG00060075969 UniProtKB/TrEMBL
  ENSSSCG00070008697 UniProtKB/TrEMBL
  ENSSSCG00070015575 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000045664 ENTREZGENE
  ENSSSCT00000045664.2 UniProtKB/TrEMBL
  ENSSSCT00000095180 ENTREZGENE
  ENSSSCT00000095180.1 UniProtKB/TrEMBL
  ENSSSCT00005024300.1 UniProtKB/TrEMBL
  ENSSSCT00015045918.1 UniProtKB/TrEMBL
  ENSSSCT00025074637.1 UniProtKB/TrEMBL
  ENSSSCT00030007485.1 UniProtKB/TrEMBL
  ENSSSCT00035032069.1 UniProtKB/TrEMBL
  ENSSSCT00040027644.1 UniProtKB/TrEMBL
  ENSSSCT00045002128.1 UniProtKB/TrEMBL
  ENSSSCT00050018601.1 UniProtKB/TrEMBL
  ENSSSCT00055060467.1 UniProtKB/TrEMBL
  ENSSSCT00055060470.1 UniProtKB/TrEMBL
  ENSSSCT00060104105.1 UniProtKB/TrEMBL
  ENSSSCT00070016878.1 UniProtKB/TrEMBL
  ENSSSCT00070030606.1 UniProtKB/TrEMBL
Gene3D-CATH 1.10.246.140 UniProtKB/TrEMBL
InterPro TF_ENY2 UniProtKB/TrEMBL
  TF_EnY2_sf UniProtKB/TrEMBL
KEGG Report ssc:100153859 UniProtKB/TrEMBL
NCBI Gene ENY2 ENTREZGENE
PANTHER PTHR12514 UniProtKB/TrEMBL
  TRANSCRIPTION AND MRNA EXPORT FACTOR ENY2 UniProtKB/TrEMBL
Pfam EnY2 UniProtKB/TrEMBL
UniProt A0A286ZK95 ENTREZGENE
  A0A4X1TFA2 ENTREZGENE, UniProtKB/TrEMBL
  A0A4X1U732 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D0Z7Z1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8D1S712 ENTREZGENE, UniProtKB/TrEMBL
  A0A8W4F814_PIG UniProtKB/TrEMBL
UniProt Secondary A0A286ZK95 UniProtKB/TrEMBL
VGNC ID VGNC:98792 ENTREZGENE