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ONTOLOGY REPORT - ANNOTATIONS

Term:G-protein alpha-subunit binding
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Accession:GO:0001965 term browser browse the term
Definition:Binding to a G-protein alpha subunit. The alpha subunit binds a guanine nucleotide.


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G-protein alpha-subunit binding term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adgrv1 adhesion G protein-coupled receptor V1 enables ISO
IBA		 (MGI:6212875|PMID:24962568)
GO_REF:0000033		 RGD
GO_Central		 PMID:24962568 GO_REF:0000033 MGI:6212875 NCBI chr 2:11,331,434...11,911,713
Ensembl chr 2:11,331,442...11,911,688 		JBrowse link
G Adrb2 adrenoceptor beta 2 IPI RGD PMID:19942860 RGD:4107483 NCBI chr18:55,642,459...55,644,501
Ensembl chr18:55,502,903...55,644,512 		JBrowse link
G Agtr2 angiotensin II receptor, type 2 TAS RGD PMID:14657020 RGD:1566502 NCBI chr  X:112,119,876...112,124,060
Ensembl chr  X:112,120,228...112,124,057 		JBrowse link
G Ccdc88a coiled coil domain containing 88A enables ISO UniProtKB:P08753|UniProtKB:P08754|UniProtKB:P63092 (PMID:19211784), (PMID:23509302), (PMID:27621449) RGD PMID:19211784 PMID:23509302 PMID:27621449 NCBI chr14:103,104,091...103,256,112
Ensembl chr14:103,103,513...103,252,368 		JBrowse link
G Ccdc88c coiled-coil domain containing 88C enables ISO UniProtKB:P08754 (PMID:26126266) RGD PMID:26126266 NCBI chr 6:120,169,752...120,289,459
Ensembl chr 6:120,169,738...120,289,555 		JBrowse link
G Crhr1 corticotropin releasing hormone receptor 1 IPI RGD PMID:20548297 PMID:20548297 RGD:5491170, RGD:5491170 NCBI chr10:89,040,186...89,083,481
Ensembl chr10:89,040,203...89,083,481 		JBrowse link
G Drd1 dopamine receptor D1 enables IPI
ISO		 UniProtKB:P63092 (PMID:33571431) RGD PMID:33571431 PMID:15798088 RGD:2302119 NCBI chr17:10,540,440...10,544,971
Ensembl chr17:10,540,558...10,545,002 		JBrowse link
G Drd2 dopamine receptor D2 enables ISO UniProtKB:P63096 (PMID:33571431) RGD PMID:33571431 NCBI chr 8:49,708,927...49,772,876
Ensembl chr 8:49,708,927...49,772,875 		JBrowse link
G Drd5 dopamine receptor D5 IPI RGD PMID:12623966 PMID:12623966 RGD:730287, RGD:730287 NCBI chr14:72,487,950...72,491,050
Ensembl chr14:72,489,347...72,490,774 		JBrowse link
G F2r coagulation factor II (thrombin) receptor enables IEA
ISS
ISO		 GO_REF:0000107
GO_REF:0000024
(MGI:5285163|PMID:20215560)		 Ensembl
UniProt
RGD		 PMID:20215560 GO_REF:0000024 GO_REF:0000107 MGI:5285163 NCBI chr 2:26,869,343...26,885,856
Ensembl chr 2:26,868,404...26,885,870 		JBrowse link
G F2rl1 F2R like trypsin receptor 1 enables ISS
ISO		 GO_REF:0000024
(MGI:5285163|PMID:20215560)		 UniProt
RGD		 PMID:20215560 GO_REF:0000024 MGI:5285163 NCBI chr 2:26,772,274...26,785,226
Ensembl chr 2:26,772,278...26,785,226 		JBrowse link
G Gas2l2 growth arrest-specific 2 like 2 enables ISO UniProtKB:P38405|UniProtKB:P50148|UniProtKB:P63092|UniProtKB:Q14344 (MGI:6355742|PMID:23994616) RGD PMID:23994616 MGI:6355742 NCBI chr10:68,222,475...68,229,877
Ensembl chr10:68,222,475...68,229,881 		JBrowse link
G Gnas GNAS complex locus IPI Alex, encoded by frameshifted ORF contained within Gnas ORF, binds Gnas RGD PMID:11447126 RGD:5509808 NCBI chr 3:163,071,003...163,136,350
Ensembl chr 3:163,071,417...163,127,262
Ensembl chr 3:163,071,417...163,127,262 		JBrowse link
G Gpsm1 G-protein signaling modulator 1 enables IDA
IBA		 GO_REF:0000033 GO_Central
RGD		 PMID:10559191 GO_REF:0000033, RGD:631950 NCBI chr 3:9,140,816...9,167,828
Ensembl chr 3:9,128,636...9,167,827 		JBrowse link
G Gpsm2 G-protein signaling modulator 2 enables ISO
IBA		 UniProtKB:P63096 (MGI:5705216|PMID:22952234)
GO_REF:0000033		 RGD
GO_Central		 PMID:22952234 GO_REF:0000033 MGI:5705216 NCBI chr 2:196,327,149...196,375,322
Ensembl chr 2:196,327,149...196,375,154 		JBrowse link
G Gria1 glutamate ionotropic receptor AMPA type subunit 1 IPI RGD PMID:19942860 RGD:4107483 NCBI chr10:41,210,713...41,527,283
Ensembl chr10:41,210,713...41,527,283 		JBrowse link
G Htr1a 5-hydroxytryptamine receptor 1A IPI RGD PMID:16772521 RGD:2303642 NCBI chr 2:36,693,462...36,698,026
Ensembl chr 2:36,694,174...36,695,442 		JBrowse link
G Htr2b 5-hydroxytryptamine receptor 2B enables IEA
ISO
ISS		 GO_REF:0000107
(PMID:15625277)
GO_REF:0000024		 Ensembl
RGD
UniProt		 PMID:15625277 GO_REF:0000024 GO_REF:0000107 NCBI chr 9:86,735,793...86,756,638
Ensembl chr 9:86,742,102...86,755,108 		JBrowse link
G Igf1r insulin-like growth factor 1 receptor IPI RGD PMID:19764351 RGD:5509824 NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777 		JBrowse link
G Igf2r insulin-like growth factor 2 receptor IDA RGD PMID:16407557 RGD:1624326 NCBI chr 1:47,979,109...48,067,501
Ensembl chr 1:47,979,109...48,067,501 		JBrowse link
G Kcnj6 potassium inwardly-rectifying channel, subfamily J, member 6 IDA RGD PMID:15731196 RGD:2316504 NCBI chr11:34,061,702...34,308,758
Ensembl chr11:34,061,708...34,308,758 		JBrowse link
G Lpar1 lysophosphatidic acid receptor 1 IMP RGD PMID:16504475 RGD:1626471 NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895 		JBrowse link
G Lpar3 lysophosphatidic acid receptor 3 IMP RGD PMID:16504475 RGD:1626471 NCBI chr 2:235,125,234...235,193,916
Ensembl chr 2:235,149,065...235,193,357 		JBrowse link
G Myh9 myosin, heavy chain 9 IDA RGD PMID:20068007 RGD:6902910 NCBI chr 7:109,343,718...109,424,457
Ensembl chr 7:109,343,706...109,424,457 		JBrowse link
G Nucb1 nucleobindin 1 enables IDA PMID:21653697 RGD
UniProt		 PMID:9647645 PMID:21653697 RGD:9831131, RGD:14929204 NCBI chr 1:95,968,325...95,999,183
Ensembl chr 1:95,968,326...96,003,220 		JBrowse link
G Nucb2 nucleobindin 2 enables IDA PMID:21653697 UniProt PMID:21653697 RGD:14929204 NCBI chr 1:170,750,830...170,787,356
Ensembl chr 1:170,750,877...170,787,353 		JBrowse link
G Oprm1 opioid receptor, mu 1 enables ISS
ISO
IEA
IBA		 GO_REF:0000024
(PMID:20214800)
GO_REF:0000107
GO_REF:0000033		 UniProt
RGD
Ensembl
GO_Central		 PMID:20214800 GO_REF:0000024 GO_REF:0000033 GO_REF:0000107 NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409 		JBrowse link
G Plcd4 phospholipase C, delta 4 enables ISS
ISO		 GO_REF:0000024
UniProtKB:P08754 (PMID:30194280)		 UniProt
RGD		 PMID:30194280 GO_REF:0000024 NCBI chr 9:76,115,523...76,158,602
Ensembl chr 9:76,117,168...76,142,453 		JBrowse link
G Ppp5c protein phosphatase 5, catalytic subunit IDA Gna12, Gna13 RGD PMID:12176367 RGD:8693757 NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456 		JBrowse link
G Rgs1 regulator of G-protein signaling 1 enables ISO UniProtKB:P63096 (PMID:18434541) RGD PMID:18434541 NCBI chr13:56,018,546...56,022,889
Ensembl chr13:56,018,554...56,022,984 		JBrowse link
G Rgs10 regulator of G-protein signaling 10 enables ISO
IEA		 UniProtKB:P08754 (PMID:18434541)
GO_REF:0000002		 RGD
InterPro		 PMID:18434541 GO_REF:0000002 NCBI chr 1:182,946,334...182,987,729
Ensembl chr 1:182,946,336...182,987,697 		JBrowse link
G Rgs12 regulator of G-protein signaling 12 IPI RGD PMID:11387333 RGD:7207387 NCBI chr14:75,715,925...75,824,012
Ensembl chr14:75,715,934...75,794,596 		JBrowse link
G Rgs14 regulator of G-protein signaling 14 enables IPI
IEA		 GO_REF:0000002 InterPro
RGD		 PMID:11387333 GO_REF:0000002, RGD:7207387 NCBI chr17:9,248,982...9,263,104
Ensembl chr17:9,249,019...9,263,104 		JBrowse link
G Rgs19 regulator of G-protein signaling 19 IDA
IPI		 Gnai1, Gnai2, Gnaz, Gnao1 RGD PMID:8986788 PMID:8986788 RGD:4892327, RGD:4892327 NCBI chr 3:168,804,532...168,813,035
Ensembl chr 3:168,804,874...168,810,097 		JBrowse link
G Rgs2 regulator of G-protein signaling 2 enables ISO UniProtKB:P21279 (PMID:19478087) RGD PMID:19478087 NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385 		JBrowse link
G Rgs22 regulator of G-protein signaling 22 enables ISO
IBA		 UniProtKB:P29992|UniProtKB:Q03113|UniProtKB:Q14344 (PMID:18703424)
GO_REF:0000033		 RGD
GO_Central		 PMID:18703424 GO_REF:0000033 NCBI chr 7:67,188,531...67,308,805
Ensembl chr 7:67,188,519...67,308,875 		JBrowse link
G Rgs4 regulator of G-protein signaling 4 IPI
IDA		 RGD PMID:20530129 PMID:9108480 PMID:28115169 RGD:7207369, RGD:7207370, RGD:13524512 NCBI chr13:81,936,775...81,943,103
Ensembl chr13:81,936,775...81,943,068 		JBrowse link
G Rgs7 regulator of G-protein signaling 7 enables IDA
ISO		 (PMID:36996198) RGD PMID:36996198 PMID:10092682 RGD:69962 NCBI chr13:86,979,269...87,408,834
Ensembl chr13:86,979,279...87,408,888 		JBrowse link
G Rgs8 regulator of G-protein signaling 8 enables IPI PMID:9394004 UniProt PMID:9394004 RGD:69963 NCBI chr13:65,804,703...65,848,955
Ensembl chr13:65,804,797...65,846,807 		JBrowse link
G Ric8a RIC8 guanine nucleotide exchange factor A enables IPI
IDA
IEA
IBA		 PMID:12509430
GO_REF:0000104
GO_REF:0000033		 UniProt
GO_Central
RGD		 PMID:12509430 PMID:12509430 GO_REF:0000033 GO_REF:0000104, RGD:633903, RGD:633903 NCBI chr 1:195,935,162...195,941,469
Ensembl chr 1:195,935,349...195,941,467 		JBrowse link
G Ric8b RIC8 guanine nucleotide exchange factor B enables ISO
IEA
IBA		 (PMID:12652642)
GO_REF:0000104
GO_REF:0000033		 RGD
UniProt
GO_Central		 PMID:12652642 GO_REF:0000033 GO_REF:0000104 NCBI chr 7:18,746,716...18,843,264
Ensembl chr 7:18,748,641...18,842,372 		JBrowse link
G Sash1 SAM and SH3 domain containing 1 enables ISO (PMID:23333244) RGD PMID:23333244 NCBI chr 1:3,119,915...3,418,536
Ensembl chr 1:3,121,332...3,439,870 		JBrowse link
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  molecular_function 20483
    binding 17534
      protein binding 14557
        G-protein alpha-subunit binding 42
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