Annotation (Toggle Detail/Summary View) Gene-Chemical Interaction AnnotationsTerm | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | (R)-noradrenaline | multiple interactions | EXP | | 6480464 | N-(1-methyl-5-indolyl)-N'-(3-methyl-5-isothiazolyl)urea inhibits the reaction [Norepinephrine results in increased expression of HTR2B protein] | CTD | PMID:20374255 | (R)-noradrenaline | increases expression | EXP | | 6480464 | Norepinephrine results in increased expression of HTR2B protein | CTD | PMID:20374255 | 1D-myo-inositol 1,4,5-trisphosphate | decreases abundance | ISO | RGD:731795 | 6480464 | HTR2B protein mutant form results in decreased abundance of Inositol 1,4,5-Trisphosphate | CTD | PMID:15625277 | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of HTR2B mRNA | CTD | PMID:16483693 | calcium atom | multiple interactions | ISO | RGD:62093 | 6480464 | Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; more ... | CTD | PMID:18758753 | calcium(0) | multiple interactions | ISO | RGD:62093 | 6480464 | Calcium promotes the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; more ... | CTD | PMID:18758753 | chlorpyrifos | decreases expression | EXP | | 6480464 | Chlorpyrifos results in decreased expression of HTR2B mRNA | CTD | PMID:17452286 | chlorpyrifos | increases expression | EXP | | 6480464 | Chlorpyrifos results in increased expression of HTR2B mRNA | CTD | PMID:18835401 | clofibrate | multiple interactions | ISO | RGD:62093 | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of HTR2B mRNA; more ... | CTD | PMID:17585979 | dasatinib (anhydrous) | increases expression | ISO | RGD:731795 | 6480464 | dasatinib results in increased expression of HTR2B mRNA | CTD | PMID:20579391 | diazinon | decreases expression | EXP | | 6480464 | Diazinon results in decreased expression of HTR2B mRNA | CTD | PMID:18835401 | dieldrin | affects expression | EXP | | 6480464 | Dieldrin affects the expression of HTR2B mRNA | CTD | PMID:18835401 | dihydroergotamine | multiple interactions | ISO | RGD:731795 | 6480464 | Ergotamine binds to and results in increased activity of HTR2B protein | CTD | PMID:11104741 | ergotamine | multiple interactions | ISO | RGD:731795 | 6480464 | Ergotamine binds to and results in increased activity of HTR2B protein | CTD | PMID:11104741 | fenfluramine | increases response to substance | ISO | RGD:731795 | 6480464 | HTR2B gene mutant form results in increased susceptibility to Fenfluramine | CTD | PMID:14659797 | fenfluramine | affects binding | ISO | RGD:731795 | 6480464 | Fenfluramine binds to HTR2B protein | CTD | PMID:10617681 | fluoxetine | increases expression | ISO | RGD:62093 | 6480464 | Fluoxetine results in increased expression of HTR2B mRNA | CTD | PMID:21083617 | fluoxetine | multiple interactions | ISO | RGD:62093 | 6480464 | Fluoxetine promotes the reaction [CQ 32085 binds to HTR2B protein]; more ... | CTD | PMID:11930908 | fluoxetine | increases activity | ISO | RGD:62093 | 6480464 | Fluoxetine results in increased activity of HTR2B protein | CTD | PMID:18758753 | fluoxetine | multiple interactions | ISO | RGD:62093 | 6480464 | Fluoxetine binds to and results in increased activity of HTR2B protein; more ... | CTD | PMID:19662385 | fluoxetine | multiple interactions | ISO | RGD:62093 | 6480464 | 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[Fluoxetine results in increased activity of HTR2B protein] which results in increased phosphorylation of MAPK1 protein]; more ... | CTD | PMID:18758753 | fluoxetine | multiple interactions | ISO | RGD:62093 | 6480464 | HTR2B protein inhibits the reaction [Fluoxetine inhibits the reaction [Excitatory Amino Acid Agents results in increased phosphorylation of MAPK1 protein]]; more ... | CTD | PMID:21320410 | glycogen | multiple interactions | ISO | RGD:62093 | 6480464 | [Fluoxetine results in increased expression of and results in increased activity of HTR2B protein] which results in increased metabolism of Glycogen | CTD | PMID:11930908 | lysergic acid diethylamide | multiple interactions | ISO | RGD:731795 | 6480464 | Lysergic Acid Diethylamide analog binds to and results in increased activity of HTR2B protein | CTD | PMID:14659797 | methamphetamine | decreases expression | EXP | | 6480464 | Methamphetamine results in decreased expression of HTR2B mRNA | CTD | PMID:15644446 | mifepristone | increases expression | ISO | RGD:731795 | 6480464 | Mifepristone results in increased expression of HTR2B mRNA | CTD | PMID:17584828 | paracetamol | multiple interactions | ISO | RGD:62093 | 6480464 | PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of HTR2B mRNA] | CTD | PMID:17585979 | pirinixic acid | increases expression | ISO | RGD:62093 | 6480464 | pirinixic acid results in increased expression of HTR2B mRNA | CTD | PMID:18301758 | ritanserin | multiple interactions | ISO | RGD:62093 | 6480464 | Ritanserin binds to and results in decreased activity of HTR2B protein | CTD | PMID:10978843 | serotonin | increases expression | ISO | RGD:62093 | 6480464 | Serotonin results in increased expression of HTR2B mRNA | CTD | PMID:21083617 | serotonin | affects response to substance | EXP | | 6480464 | HTR2B protein affects the susceptibility to Serotonin | CTD | PMID:8627522 | tetrachloromethane | affects expression | ISO | RGD:62093 | 6480464 | Carbon Tetrachloride affects the expression of HTR2B mRNA | CTD | PMID:17484886 | | ||||||||||||||||||||||||||||||||||||||||||||||||||||||
Gene Ontology AnnotationsBiological Process











