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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:antimutagen
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Accession:CHEBI:73190 term browser browse the term
Definition:An agent that reduces or interferes with the mutagenic actions or effects of a substance.
Synonyms:related_synonym: antimutagenic agent;   antimutagenic agents;   antimutagens


show annotations for term's descendants           Sort by:
anthraflavic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ahr aryl-hydrocarbon receptor multiple interactions ISO 2,6-dihydroxyanthraquinone inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of AHR protein] CTD PMID:19269596 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Alb albumin affects binding ISO 2,6-dihydroxyanthraquinone binds to ALB protein CTD PMID:16404478 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO 2,6-dihydroxyanthraquinone results in increased expression of CYP1A1 mRNA CTD PMID:11502733 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 increases expression ISO 2,6-dihydroxyanthraquinone results in increased expression of CYP1B1 mRNA CTD PMID:11502733 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases glucuronidation ISO UGT1A1 protein results in increased glucuronidation of 2,6-dihydroxyanthraquinone CTD PMID:12756209 PMID:14557274 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation ISO UGT1A10 protein results in increased glucuronidation of 2,6-dihydroxyanthraquinone CTD PMID:14557274 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a9 UDP glucuronosyltransferase 1 family, polypeptide A9 increases glucuronidation ISO UGT1A9 protein results in increased glucuronidation of 2,6-dihydroxyanthraquinone CTD PMID:14557274 NCBI chr 1:87,998,501...88,147,724
Ensembl chr 1:87,998,522...88,146,719 		JBrowse link
dibenzoylmethane term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) increases expression ISO dibenzoylmethane results in increased expression of ABCG2 protein CTD PMID:17077187 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Akt1 thymoma viral proto-oncogene 1 decreases phosphorylation
multiple interactions		 EXP dibenzoylmethane results in decreased phosphorylation of AKT1 protein
[dibenzoylmethane co-treated with sulforaphane] results in decreased phosphorylation of AKT1 protein		 CTD PMID:17942926 NCBI chr12:112,620,260...112,641,266
Ensembl chr12:112,620,255...112,641,318 		JBrowse link
G Bad BCL2-associated agonist of cell death multiple interactions
increases expression		 ISO ODC1 protein inhibits the reaction [dibenzoylmethane results in increased expression of BAD protein] CTD PMID:21523861 NCBI chr19:6,919,229...6,929,273
Ensembl chr19:6,919,229...6,929,267 		JBrowse link
G Bax BCL2-associated X protein increases expression EXP dibenzoylmethane results in increased expression of BAX protein CTD PMID:17942926 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2 B cell leukemia/lymphoma 2 multiple interactions ISO dibenzoylmethane inhibits the reaction [ESR1 protein binds to BCL2 enhancer]; dibenzoylmethane inhibits the reaction [Estradiol results in increased expression of BCL2 mRNA] CTD PMID:16051634 NCBI chr 1:106,465,906...106,642,020
Ensembl chr 1:106,465,908...106,642,004 		JBrowse link
G Casp9 caspase 9 multiple interactions ISO ODC1 protein inhibits the reaction [dibenzoylmethane results in increased activity of CASP9 protein] CTD PMID:21523861 NCBI chr 4:141,520,923...141,543,289
Ensembl chr 4:141,520,923...141,543,287 		JBrowse link
G Cbr3 carbonyl reductase 3 increases expression
multiple interactions		 EXP dibenzoylmethane results in increased expression of CBR3 mRNA
[sulforaphane co-treated with dibenzoylmethane] results in increased expression of CBR3 mRNA		 CTD PMID:17942926 NCBI chr16:93,480,107...93,487,879
Ensembl chr16:93,480,103...93,487,878 		JBrowse link
G Ccnd1 cyclin D1 decreases expression EXP dibenzoylmethane results in decreased expression of CCND1 protein CTD PMID:17942926 NCBI chr 7:144,483,668...144,493,568
Ensembl chr 7:144,483,668...144,493,662 		JBrowse link
G Cdkn1a cyclin dependent kinase inhibitor 1A decreases expression EXP dibenzoylmethane results in decreased expression of CDKN1A protein CTD PMID:17942926 NCBI chr17:29,309,953...29,319,696
Ensembl chr17:29,309,950...29,319,701 		JBrowse link
G Clu clusterin decreases expression
multiple interactions		 EXP dibenzoylmethane results in decreased expression of CLU mRNA
[sulforaphane co-treated with dibenzoylmethane] results in decreased expression of CLU mRNA		 CTD PMID:17942926 NCBI chr14:66,206,093...66,218,992
Ensembl chr14:66,205,932...66,218,996 		JBrowse link
G Ephx1 epoxide hydrolase 1, microsomal increases activity
multiple interactions
increases expression		 EXP dibenzoylmethane results in increased activity of EPHX1 protein
[sulforaphane co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA
dibenzoylmethane results in increased expression of EPHX1 mRNA		 CTD PMID:3621371 PMID:17942926 NCBI chr 1:180,817,121...180,845,134
Ensembl chr 1:180,803,775...180,848,469 		JBrowse link
G Esr1 estrogen receptor 1 (alpha) multiple interactions ISO dibenzoylmethane inhibits the reaction [ESR1 protein binds to BCL2 enhancer]; dibenzoylmethane inhibits the reaction [ESR1 protein binds to MYC enhancer]; dibenzoylmethane inhibits the reaction [ESR1 protein binds to TERT enhancer] CTD PMID:16051634 NCBI chr10:4,561,989...4,955,633
Ensembl chr10:4,561,593...4,955,614 		JBrowse link
G Gclc glutamate-cysteine ligase, catalytic subunit increases expression
multiple interactions		 EXP dibenzoylmethane results in increased expression of GCLC mRNA
[sulforaphane co-treated with dibenzoylmethane] results in increased expression of GCLC mRNA		 CTD PMID:17942926 NCBI chr 9:77,661,817...77,701,771
Ensembl chr 9:77,661,817...77,701,767 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 increases expression
multiple interactions		 EXP dibenzoylmethane results in increased expression of GSTM1 mRNA
[sulforaphane co-treated with dibenzoylmethane] results in increased expression of GSTM1 mRNA		 CTD PMID:17942926 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
increases expression		 EXP [sulforaphane co-treated with dibenzoylmethane] results in increased expression of GSTM3 mRNA
dibenzoylmethane results in increased expression of GSTM3 mRNA		 CTD PMID:17942926 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002 		JBrowse link
G Hras Harvey rat sarcoma virus oncogene multiple interactions ISO dibenzoylmethane inhibits the reaction [Estradiol results in increased expression of HRAS mRNA] CTD PMID:16051634 NCBI chr 7:140,770,839...140,773,938
Ensembl chr 7:140,769,018...140,773,918 		JBrowse link
G Myc myelocytomatosis oncogene multiple interactions ISO dibenzoylmethane inhibits the reaction [ESR1 protein binds to MYC enhancer] CTD PMID:16051634 NCBI chr15:61,857,190...61,862,210
Ensembl chr15:61,857,240...61,862,223 		JBrowse link
G Odc1 ornithine decarboxylase, structural 1 multiple interactions
decreases response to substance		 ISO ODC1 protein inhibits the reaction [dibenzoylmethane results in increased abundance of Reactive Oxygen Species]; ODC1 protein inhibits the reaction [dibenzoylmethane results in increased activity of CASP9 protein]; ODC1 protein inhibits the reaction [dibenzoylmethane results in increased expression of BAD protein]
ODC1 protein results in decreased susceptibility to dibenzoylmethane		 CTD PMID:21523861 NCBI chr12:17,594,906...17,601,503
Ensembl chr12:17,594,795...17,601,506 		JBrowse link
G Ptgr1 prostaglandin reductase 1 multiple interactions EXP [sulforaphane co-treated with dibenzoylmethane] results in increased expression of PTGR1 mRNA CTD PMID:17942926 NCBI chr 4:58,965,590...58,987,131
Ensembl chr 4:58,965,439...58,987,119 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression EXP dibenzoylmethane results in decreased expression of PTGS2 protein CTD PMID:17942926 NCBI chr 1:149,975,851...149,983,978
Ensembl chr 1:149,975,782...149,983,978 		JBrowse link
G Tert telomerase reverse transcriptase multiple interactions ISO dibenzoylmethane inhibits the reaction [ESR1 protein binds to TERT enhancer]; dibenzoylmethane inhibits the reaction [Estradiol results in increased expression of TERT mRNA] CTD PMID:16051634 NCBI chr13:73,775,030...73,797,962
Ensembl chr13:73,775,030...73,797,962 		JBrowse link
G Ugt2b5 UDP glucuronosyltransferase 2 family, polypeptide B5 multiple interactions
increases expression		 EXP [sulforaphane co-treated with dibenzoylmethane] results in increased expression of UGT2B5 mRNA
dibenzoylmethane results in increased expression of UGT2B5 mRNA		 CTD PMID:17942926 NCBI chr 5:87,272,805...87,288,199
Ensembl chr 5:87,272,819...87,288,177 		JBrowse link
oltipraz term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abcb11 ATP-binding cassette, sub-family B member 11 decreases expression ISO oltipraz results in decreased expression of ABCB11 mRNA CTD PMID:16837569 NCBI chr 2:69,068,626...69,172,960
Ensembl chr 2:69,068,626...69,172,958 		JBrowse link
G Abcb1a ATP-binding cassette, sub-family B member 1A increases expression ISO oltipraz results in increased expression of ABCB1 mRNA CTD PMID:16837569 NCBI chr 5:8,617,091...8,798,575
Ensembl chr 5:8,710,077...8,798,575 		JBrowse link
G Abcc1 ATP-binding cassette, sub-family C member 1 multiple interactions EXP [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC1 protein CTD PMID:18032408 NCBI chr16:14,179,317...14,292,743
Ensembl chr16:14,179,422...14,293,601 		JBrowse link
G Abcc2 ATP-binding cassette, sub-family member 2 increases expression
multiple interactions		 ISO
EXP		 oltipraz results in increased expression of ABCC2 mRNA; oltipraz results in increased expression of ABCC2 protein
[Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC2 protein; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA		 CTD PMID:12920174 PMID:15833929 PMID:16837569 PMID:18032408 PMID:25752797 More... NCBI chr19:43,770,747...43,826,771
Ensembl chr19:43,770,631...43,829,179 		JBrowse link
G Abcc3 ATP-binding cassette, sub-family C member 3 increases expression
multiple interactions		 ISO
EXP		 oltipraz results in increased expression of ABCC3 mRNA
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC3 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of ABCC3 mRNA]
[oltipraz results in increased expression of ABCC3 protein] which affects the export of Acetaminophen metabolite
oltipraz results in increased expression of ABCC3 mRNA; oltipraz results in increased expression of ABCC3 protein		 CTD PMID:12920174 PMID:15833929 PMID:16837569 PMID:22496397 PMID:30114225 NCBI chr11:94,234,121...94,283,843
Ensembl chr11:94,234,121...94,283,823 		JBrowse link
G Abcc4 ATP-binding cassette, sub-family C member 4 multiple interactions
increases expression		 EXP
ISO		 [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC4 protein; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC4 mRNA]
oltipraz results in increased expression of ABCC4 mRNA; oltipraz results in increased expression of ABCC4 protein
oltipraz promotes the reaction [ABCC4 protein results in increased transport of Arsenic]		 CTD PMID:15833929 PMID:18032408 PMID:20395535 PMID:22496397 PMID:25752797 NCBI chr14:118,720,104...118,945,475
Ensembl chr14:118,720,104...118,943,631 		JBrowse link
G Abcc5 ATP-binding cassette, sub-family C member 5 multiple interactions
increases expression		 EXP [Lithocholic Acid co-treated with oltipraz] results in increased expression of ABCC5 protein; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC5 mRNA
oltipraz results in increased expression of ABCC5 mRNA		 CTD PMID:15833929 PMID:18032408 NCBI chr16:20,150,053...20,245,178
Ensembl chr16:20,150,053...20,245,144 		JBrowse link
G Abcc6 ATP-binding cassette, sub-family C member 6 multiple interactions
increases expression		 EXP [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC6 mRNA
oltipraz results in increased expression of ABCC6 mRNA		 CTD PMID:15833929 NCBI chr 7:45,625,804...45,679,915
Ensembl chr 7:45,616,979...45,679,726 		JBrowse link
G Abcg2 ATP binding cassette subfamily G member 2 (Junior blood group) multiple interactions
increases expression
increases activity		 ISO oltipraz promotes the reaction [ABCG2 protein results in increased transport of Benzo(a)pyrene metabolite]
oltipraz results in increased expression of ABCG2 mRNA
oltipraz results in increased activity of ABCG2 protein		 CTD PMID:15917307 PMID:16837569 NCBI chr 6:58,561,476...58,669,436
Ensembl chr 6:58,561,508...58,672,661 		JBrowse link
G Abcg5 ATP binding cassette subfamily G member 5 multiple interactions EXP [oltipraz co-treated with NFE2L2 protein mutant form] affects the expression of ABCG5 mRNA CTD PMID:22496397 NCBI chr17:84,965,602...84,990,439
Ensembl chr17:84,965,662...84,990,439 		JBrowse link
G Ace angiotensin I converting enzyme multiple interactions EXP
ISO		 oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE protein]]
oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of ACE mRNA]]		 CTD PMID:29211853 NCBI chr11:105,858,774...105,880,790
Ensembl chr11:105,858,771...105,880,790 		JBrowse link
G Ace2 angiotensin converting enzyme 2 multiple interactions EXP
ISO		 oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 protein]]
oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in decreased expression of ACE2 mRNA]]		 CTD PMID:29211853 NCBI chr  X:162,922,338...162,971,414
Ensembl chr  X:162,922,328...162,971,416 		JBrowse link
G Agt angiotensinogen multiple interactions ISO
EXP		 oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of AGT mRNA]]
oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of AGT mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of AGT protein]]		 CTD PMID:29211853 NCBI chr 8:125,283,326...125,296,445
Ensembl chr 8:125,283,273...125,296,445 		JBrowse link
G Ahr aryl-hydrocarbon receptor multiple interactions
increases activity		 ISO [oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]] which results in increased expression of CYP1A1 mRNA; oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]; resveratrol inhibits the reaction [[oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]] which results in increased expression of CYP1A1 mRNA]
oltipraz results in increased activity of AHR protein		 CTD PMID:11959854 NCBI chr12:35,547,978...35,584,988
Ensembl chr12:35,547,973...35,585,037 		JBrowse link
G Alb albumin decreases expression ISO oltipraz results in decreased expression of ALB mRNA CTD PMID:9395210 NCBI chr 5:90,608,729...90,624,461
Ensembl chr 5:90,608,756...90,624,461 		JBrowse link
G Aldh1a1 aldehyde dehydrogenase family 1, subfamily A1 multiple interactions
increases expression		 EXP [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ALDH1A1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ALDH1A1 mRNA] CTD PMID:17998271 PMID:22496397 NCBI chr19:20,469,947...20,620,827
Ensembl chr19:20,470,079...20,620,829 		JBrowse link
G Aldh1a7 aldehyde dehydrogenase family 1, subfamily A7 increases expression EXP oltipraz results in increased expression of ALDH1A7 mRNA CTD PMID:17998271 PMID:22496397 NCBI chr19:20,670,318...20,704,920
Ensembl chr19:20,670,317...20,704,926 		JBrowse link
G Bax BCL2-associated X protein multiple interactions EXP
ISO		 [Lithocholic Acid co-treated with oltipraz] results in increased expression of BAX mRNA
oltipraz inhibits the reaction [Acetaminophen results in increased expression of BAX protein]		 CTD PMID:19433268 PMID:33959992 NCBI chr 7:45,111,124...45,116,332
Ensembl chr 7:45,111,121...45,116,322 		JBrowse link
G Bcl2l1 BCL2-like 1 multiple interactions EXP [Lithocholic Acid co-treated with oltipraz] results in increased expression of BCL2L1 mRNA CTD PMID:19433268 NCBI chr 2:152,600,652...152,673,632
Ensembl chr 2:152,622,588...152,673,648 		JBrowse link
G Casp3 caspase 3 multiple interactions ISO oltipraz inhibits the reaction [Acetaminophen results in increased expression of CASP3 protein] CTD PMID:33959992 NCBI chr 8:47,070,326...47,092,733
Ensembl chr 8:47,070,326...47,092,724 		JBrowse link
G Cebpb CCAAT/enhancer binding protein beta multiple interactions ISO [Dexamethasone co-treated with oltipraz] results in increased activity of CEBPB protein; N-acetylsphingosine inhibits the reaction [oltipraz results in increased localization of CEBPB protein]; oltipraz promotes the reaction [CEBPB protein binds to GSTA2 promoter]; oltipraz results in increased localization of and results in increased activity of CEBPB protein CTD PMID:12509401 PMID:15319326 PMID:15870285 NCBI chr 2:167,530,835...167,532,352
Ensembl chr 2:167,530,835...167,532,338 		JBrowse link
G Ces1d carboxylesterase 1D increases expression
multiple interactions		 EXP oltipraz results in increased expression of CES1 mRNA
NFE2L2 protein promotes the reaction [oltipraz results in increased expression of CES1 mRNA]		 CTD PMID:30114225 NCBI chr 8:93,892,700...93,924,432
Ensembl chr 8:93,892,696...93,924,466 		JBrowse link
G Ces1g carboxylesterase 1G multiple interactions
increases expression		 EXP NFE2L2 protein affects the reaction [oltipraz results in increased expression of CES1G mRNA] CTD PMID:22429928 NCBI chr 8:94,028,997...94,063,837
Ensembl chr 8:94,028,997...94,063,936 		JBrowse link
G Ces2b carboxyesterase 2B increases expression EXP oltipraz results in increased expression of CES2B mRNA CTD PMID:22429928 NCBI chr 8:105,555,130...105,566,725
Ensembl chr 8:105,558,204...105,566,725 		JBrowse link
G Ces2c carboxylesterase 2C increases expression
multiple interactions		 EXP oltipraz results in increased expression of CES2C mRNA
NFE2L2 protein affects the reaction [oltipraz results in increased expression of CES2C mRNA]		 CTD PMID:22429928 NCBI chr 8:105,573,700...105,581,115
Ensembl chr 8:105,573,700...105,581,115 		JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
affects metabolic processing
decreases activity
affects activity		 ISO 1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [oltipraz results in increased expression of CYP1A1 mRNA]; 2-aminoethoxydiphenyl borate inhibits the reaction [[oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA]; [oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]] which results in increased expression of CYP1A1 mRNA; [oltipraz results in increased abundance of Calcium] which results in increased expression of CYP1A1 mRNA; oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]; oltipraz results in increased expression of and results in increased activity of CYP1A1 protein; resveratrol inhibits the reaction [[oltipraz promotes the reaction [AHR protein binds to CYP1A1 promoter]] which results in increased expression of CYP1A1 mRNA]; resveratrol inhibits the reaction [oltipraz results in increased expression of CYP1A1 mRNA]
CYP1A1 protein affects the metabolism of oltipraz
oltipraz results in increased expression of CYP1A1 mRNA; oltipraz results in increased expression of CYP1A1 protein
oltipraz metabolite results in decreased activity of CYP1A1 protein
oltipraz affects the activity of CYP1A1 protein		 CTD PMID:10775323 PMID:11959854 PMID:15831204 PMID:15890477 PMID:15920769 NCBI chr 9:57,595,211...57,611,107
Ensembl chr 9:57,595,211...57,611,107 		JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity
increases expression
multiple interactions
increases activity
affects metabolic processing		 ISO
EXP		 oltipraz metabolite results in decreased activity of CYP1A2 protein; oltipraz results in decreased activity of CYP1A2 protein
oltipraz results in increased expression of CYP1A2 mRNA
NFE2L2 protein affects the reaction [oltipraz results in increased expression of CYP1A2 mRNA]
oltipraz results in increased activity of CYP1A2 protein
oltipraz inhibits the reaction [CYP1A2 results in increased activity of 2-amino-3,4-dimethylimidazo(4,5-f)quinoline]
CYP1A2 protein affects the metabolism of oltipraz		 CTD PMID:8625305 PMID:10775323 PMID:15831204 PMID:15920769 PMID:22496397 NCBI chr 9:57,584,220...57,590,938
Ensembl chr 9:57,584,220...57,590,986 		JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
affects activity
increases expression		 ISO oltipraz metabolite results in decreased activity of CYP1B1 protein
oltipraz affects the activity of CYP1B1 protein
oltipraz results in increased expression of CYP1B1 mRNA		 CTD PMID:10775323 PMID:15890477 NCBI chr17:80,014,369...80,022,490
Ensembl chr17:80,008,966...80,022,490 		JBrowse link
G Cyp2b10 cytochrome P450, family 2, subfamily b, polypeptide 10 increases expression
decreases activity		 EXP
ISO		 oltipraz results in increased expression of CYP2B10 mRNA
oltipraz results in increased expression of CYP2B6 mRNA; oltipraz results in increased expression of CYP2B6 protein
oltipraz results in decreased activity of CYP2B6 protein		 CTD PMID:17627975 PMID:19833192 NCBI chr 7:25,597,083...25,626,049
Ensembl chr 7:25,597,045...25,626,049 		JBrowse link
G Cyp2b13 cytochrome P450, family 2, subfamily b, polypeptide 13 affects metabolic processing ISO CYP2B2 protein affects the metabolism of oltipraz CTD PMID:15831204 PMID:15920769 NCBI chr 7:25,760,813...25,795,622
Ensembl chr 7:25,760,922...25,795,622 		JBrowse link
G Cyp2c52-ps cytochrome P450, family 2, subfamily c, polypeptide 52, pseudogene affects metabolic processing ISO CYP2C11 protein affects the metabolism of oltipraz CTD PMID:15831204 PMID:15920769 NCBI chr19:38,965,106...38,992,071
Ensembl chr19:38,965,091...38,991,733 		JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 affects activity ISO oltipraz affects the activity of CYP2E1 protein CTD PMID:10775323 NCBI chr 7:140,343,732...140,354,903
Ensembl chr 7:140,343,652...140,354,900 		JBrowse link
G Cyp3a11 cytochrome P450, family 3, subfamily a, polypeptide 11 increases expression EXP oltipraz results in increased expression of CYP3A11 mRNA CTD PMID:22496397 NCBI chr 5:145,791,417...145,816,664
Ensembl chr 5:145,791,236...145,816,774 		JBrowse link
G Cyp4a10 cytochrome P450, family 4, subfamily a, polypeptide 10 increases expression EXP oltipraz results in increased expression of CYP4A10 mRNA CTD PMID:25689681 NCBI chr 4:115,375,484...115,390,846
Ensembl chr 4:115,375,461...115,390,846 		JBrowse link
G Cyp4a14 cytochrome P450, family 4, subfamily a, polypeptide 14 increases expression EXP oltipraz results in increased expression of CYP4A14 mRNA CTD PMID:22496397 NCBI chr 4:115,343,397...115,353,355
Ensembl chr 4:115,343,397...115,353,339 		JBrowse link
G Got1 glutamic-oxaloacetic transaminase 1, soluble multiple interactions ISO oltipraz inhibits the reaction [Acetaminophen results in increased activity of GOT1 protein] CTD PMID:33959992 NCBI chr19:43,488,191...43,514,743
Ensembl chr19:43,488,191...43,513,044 		JBrowse link
G Gpt glutamic pyruvic transaminase, soluble multiple interactions ISO oltipraz inhibits the reaction [Acetaminophen results in increased activity of GPT protein] CTD PMID:33959992 NCBI chr15:76,580,926...76,583,875
Ensembl chr15:76,579,916...76,583,886 		JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO oltipraz inhibits the reaction [Acetaminophen results in decreased activity of GPX3 protein] CTD PMID:33959992 NCBI chr11:54,793,680...54,801,213
Ensembl chr11:54,793,279...54,801,203 		JBrowse link
G Gsta1 glutathione S-transferase, alpha 1 (Ya) increases activity
multiple interactions
increases expression		 ISO
EXP		 oltipraz results in increased activity of GSTA5 protein
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTA1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTA1 mRNA]
oltipraz results in increased expression of GSTA1 mRNA; oltipraz results in increased expression of GSTA1 protein
oltipraz results in increased expression of GSTA5 mRNA; oltipraz results in increased expression of GSTA5 protein		 CTD PMID:8051171 PMID:8625305 PMID:9203627 PMID:9328168 PMID:11309284 More... NCBI chr 9:78,137,951...78,149,965
Ensembl chr 9:78,137,938...78,149,966 		JBrowse link
G Gsta2 glutathione S-transferase, alpha 2 (Yc2) increases expression
multiple interactions		 ISO
EXP		 oltipraz results in increased expression of GSTA2 mRNA; oltipraz results in increased expression of GSTA2 protein
2-tert-butylhydroquinone inhibits the reaction [oltipraz results in increased expression of GSTA2 mRNA]; Dexamethasone inhibits the reaction [oltipraz results in increased expression of GSTA2 mRNA]; Dexamethasone inhibits the reaction [oltipraz results in increased expression of GSTA2 protein]; N-acetylsphingosine inhibits the reaction [oltipraz results in increased expression of GSTA2 protein]; oltipraz promotes the reaction [CEBPB protein binds to GSTA2 promoter]		 CTD PMID:9203627 PMID:11309284 PMID:12242683 PMID:12509401 PMID:15155840 More... NCBI chr 9:78,238,300...78,254,474
Ensembl chr 9:78,238,300...78,263,070 		JBrowse link
G Gstm1 glutathione S-transferase, mu 1 multiple interactions
increases expression		 EXP
ISO		 [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM1 mRNA] CTD PMID:9203627 PMID:18723825 PMID:22496397 NCBI chr 3:107,919,566...107,925,289
Ensembl chr 3:107,919,571...107,925,289 		JBrowse link
G Gstm2 glutathione S-transferase, mu 2 multiple interactions
increases expression		 EXP [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM2 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM2 mRNA] CTD PMID:18723825 PMID:22496397 NCBI chr 3:107,889,018...107,893,736
Ensembl chr 3:107,889,018...107,893,769 		JBrowse link
G Gstm4 glutathione S-transferase, mu 4 multiple interactions
increases expression		 EXP [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM4 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM4 mRNA] CTD PMID:18723825 PMID:22496397 NCBI chr 3:107,937,887...107,952,495
Ensembl chr 3:107,947,724...107,952,210 		JBrowse link
G Gstm5 glutathione S-transferase, mu 5 multiple interactions
increases expression		 EXP
ISO		 [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM3 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM3 mRNA]
oltipraz results in increased expression of GSTM3 protein		 CTD PMID:9794803 PMID:18723825 PMID:22496397 NCBI chr 3:107,803,240...107,806,002
Ensembl chr 3:107,803,137...107,806,002 		JBrowse link
G Gstp1 glutathione S-transferase, pi 1 increases expression
multiple interactions		 EXP
ISO		 oltipraz results in increased expression of GSTP1 mRNA
oltipraz results in increased expression of GSTP1 protein
oltipraz results in increased expression of and results in increased activity of GSTP1 protein		 CTD PMID:9794803 PMID:15374950 PMID:16950796 NCBI chr19:4,085,411...4,087,912
Ensembl chr19:4,085,407...4,087,985 		JBrowse link
G Gstt1 glutathione S-transferase, theta 1 affects localization
increases expression		 ISO oltipraz affects the localization of GSTT1 protein
oltipraz results in increased expression of GSTT1 protein		 CTD PMID:9794803 PMID:9855024 PMID:10413528 NCBI chr10:75,619,647...75,634,418
Ensembl chr10:75,619,647...75,634,418 		JBrowse link
G Hnf1a HNF1 homeobox A multiple interactions ISO oltipraz inhibits the reaction [Acetaminophen results in decreased expression of HNF1A mRNA]; oltipraz inhibits the reaction [Acetaminophen results in decreased expression of HNF1A protein] CTD PMID:31385618 PMID:33959992 NCBI chr 5:115,087,039...115,109,121
Ensembl chr 5:115,087,039...115,109,153 		JBrowse link
G Ins2 insulin II multiple interactions EXP oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE protein]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of ACE2 protein]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of AGT mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of AGT protein]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of MAS1 mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of MAS1 protein]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 protein]]; oltipraz inhibits the reaction [trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 mRNA]] CTD PMID:29211853 NCBI chr 7:142,232,393...142,233,463
Ensembl chr 7:142,232,393...142,297,118 		JBrowse link
G Ivl involucrin decreases expression ISO oltipraz results in decreased expression of IVL protein CTD PMID:10769631 NCBI chr 3:92,478,206...92,481,097
Ensembl chr 3:92,478,209...92,481,042 		JBrowse link
G Jun jun proto-oncogene multiple interactions ISO oltipraz inhibits the reaction [Acetaminophen results in increased phosphorylation of JUN protein] CTD PMID:33959992 NCBI chr 4:94,937,273...94,940,459
Ensembl chr 4:94,937,271...94,940,459 		JBrowse link
G Mapk8 mitogen-activated protein kinase 8 multiple interactions ISO oltipraz inhibits the reaction [Acetaminophen results in increased phosphorylation of MAPK8 protein] CTD PMID:33959992 NCBI chr14:33,099,855...33,169,213
Ensembl chr14:33,099,855...33,169,115 		JBrowse link
G Mas1 MAS1 oncogene multiple interactions ISO
EXP		 oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in decreased expression of MAS1 mRNA]]
oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of MAS1 mRNA]]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of MAS1 protein]]		 CTD PMID:29211853 NCBI chr17:13,056,981...13,087,037
Ensembl chr17:13,059,966...13,087,030 		JBrowse link
G Mcl1 myeloid cell leukemia sequence 1 multiple interactions EXP [Lithocholic Acid co-treated with oltipraz] results in increased expression of MCL1 mRNA CTD PMID:19433268 NCBI chr 3:95,564,017...95,583,553
Ensembl chr 3:95,566,099...95,570,487 		JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase increases expression
multiple interactions		 ISO oltipraz results in increased expression of MGMT mRNA
oltipraz results in increased expression of and results in increased activity of MGMT protein		 CTD PMID:16950796 NCBI chr 7:136,496,315...136,732,001
Ensembl chr 7:136,496,343...136,731,995 		JBrowse link
G Mgst3 microsomal glutathione S-transferase 3 multiple interactions
increases expression		 EXP [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of MGST3 mRNA
oltipraz results in increased expression of MGST3 mRNA		 CTD PMID:18723825 PMID:22496397 NCBI chr 1:167,199,535...167,221,410
Ensembl chr 1:167,199,535...167,221,410 		JBrowse link
G Nfe2l2 nuclear factor, erythroid derived 2, like 2 affects activity
multiple interactions
increases activity
affects response to substance		 EXP
ISO		 oltipraz affects the activity of NFE2L2 protein
oltipraz inhibits the reaction [trigonelline inhibits the reaction [Glucose results in increased expression of NFE2L2 protein]]
oltipraz results in increased activity of NFE2L2 protein
[oltipraz co-treated with NFE2L2 protein mutant form] affects the expression of ABCG5 mRNA; [oltipraz co-treated with NFE2L2 protein mutant form] results in decreased expression of UGT2B1 mRNA; [oltipraz co-treated with NFE2L2 protein mutant form] results in decreased expression of UGT2B35 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC2 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC3 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC4 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC5 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ABCC6 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of ALDH1A1 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTA1 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTA4 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM1 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM2 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM3 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of GSTM4 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of MGST3 mRNA; [oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC3 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ABCC4 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of ALDH1A1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of CES1G mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of CES2C mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of CYP1A2 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTA1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTA4 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM2 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM3 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of GSTM4 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of NQO1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of SULT3A1 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT1A6A mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT2B34 mRNA]; NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT2B36 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of ABCC3 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of CES1 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of NQO1 mRNA]; oltipraz affects the reaction [trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 protein]]; oltipraz binds to and results in increased activity of NFE2L2 protein; oltipraz inhibits the reaction [trigonelline affects the reaction [INS2 protein affects the expression of NFE2L2 mRNA]]
NFE2L2 protein affects the susceptibility to oltipraz		 CTD PMID:11309284 PMID:15833929 PMID:15919853 PMID:19150646 PMID:20086057 More... NCBI chr 2:75,505,860...75,535,007
Ensembl chr 2:75,505,857...75,534,985 		JBrowse link
G Nqo1 NAD(P)H dehydrogenase, quinone 1 increases activity
multiple interactions
increases expression		 ISO
EXP		 oltipraz results in increased activity of NQO1 protein
oltipraz promotes the reaction [Cisplatin results in increased expression of NQO1 mRNA]
oltipraz metabolite results in increased expression of NQO1 protein; oltipraz results in increased expression of NQO1 mRNA; oltipraz results in increased expression of NQO1 protein
[oltipraz results in increased activity of NFE2L2 protein] which results in increased expression of NQO1 mRNA; NFE2L2 protein affects the reaction [oltipraz results in increased expression of NQO1 mRNA]; NFE2L2 protein promotes the reaction [oltipraz results in increased expression of NQO1 mRNA]; oltipraz promotes the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of NQO1 mRNA]		 CTD PMID:11309284 PMID:12407167 PMID:15919853 PMID:17627975 PMID:18488193 More... NCBI chr 8:108,114,856...108,139,012
Ensembl chr 8:108,114,857...108,129,838 		JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 multiple interactions EXP oltipraz inhibits the reaction [Lithocholic Acid affects the localization of and results in increased activity of NR1I3 protein] CTD PMID:19433268 NCBI chr 1:171,041,503...171,046,414
Ensembl chr 1:171,041,539...171,048,270 		JBrowse link
G Slc10a1 solute carrier family 10 (sodium/bile acid cotransporter family), member 1 decreases expression ISO oltipraz results in decreased expression of SLC10A1 mRNA CTD PMID:16837569 NCBI chr12:80,999,959...81,015,479
Ensembl chr12:80,999,957...81,015,479 		JBrowse link
G Slc22a7 solute carrier family 22 (organic anion transporter), member 7 decreases expression ISO oltipraz results in decreased expression of SLC22A7 mRNA CTD PMID:16837569 NCBI chr17:46,743,111...46,749,403
Ensembl chr17:46,743,109...46,749,383 		JBrowse link
G Slco1a1 solute carrier organic anion transporter family, member 1a1 decreases expression EXP oltipraz results in decreased expression of SLCO1A1 mRNA CTD PMID:15919853 PMID:22496397 NCBI chr 6:141,853,007...141,892,688
Ensembl chr 6:141,853,008...141,892,688 		JBrowse link
G Slco1b2 solute carrier organic anion transporter family, member 1b2 decreases expression ISO oltipraz results in decreased expression of SLCO1B3 mRNA CTD PMID:16837569 NCBI chr 6:141,575,178...141,632,372
Ensembl chr 6:141,575,244...141,632,372 		JBrowse link
G Slco2b1 solute carrier organic anion transporter family, member 2b1 increases expression EXP oltipraz results in increased expression of SLCO2B1 mRNA CTD PMID:15919853 NCBI chr 7:99,307,011...99,360,547
Ensembl chr 7:99,307,011...99,360,547 		JBrowse link
G Sod1 superoxide dismutase 1, soluble multiple interactions ISO oltipraz inhibits the reaction [Acetaminophen results in decreased activity of SOD1 protein] CTD PMID:33959992 NCBI chr16:90,017,650...90,023,221
Ensembl chr16:90,017,642...90,023,217 		JBrowse link
G Sod2 superoxide dismutase 2, mitochondrial increases expression ISO oltipraz results in increased expression of SOD2 mRNA CTD PMID:9395210 NCBI chr17:13,226,726...13,237,006
Ensembl chr17:13,225,733...13,258,950 		JBrowse link
G Sult3a1 sulfotransferase family 3A, member 1 increases expression
multiple interactions		 EXP oltipraz results in increased expression of SULT3A1 mRNA
NFE2L2 protein affects the reaction [oltipraz results in increased expression of SULT3A1 mRNA]		 CTD PMID:22496397 NCBI chr10:33,727,016...33,755,471
Ensembl chr10:33,733,717...33,755,528 		JBrowse link
G Txnrd1 thioredoxin reductase 1 increases expression EXP oltipraz results in increased expression of TXNRD1 mRNA CTD PMID:16451816 NCBI chr10:82,669,785...82,733,558
Ensembl chr10:82,669,785...82,733,546 		JBrowse link
G Ucp2 uncoupling protein 2 (mitochondrial, proton carrier) multiple interactions EXP oltipraz inhibits the reaction [Doxorubicin results in decreased expression of UCP2 protein] CTD PMID:29061315 NCBI chr 7:100,142,565...100,148,832
Ensembl chr 7:100,142,544...100,151,227 		JBrowse link
G Ugt1a1 UDP glucuronosyltransferase 1 family, polypeptide A1 increases expression
multiple interactions		 EXP oltipraz results in increased expression of UGT1A1 mRNA
oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A7 mRNA]		 CTD PMID:15374950 PMID:19144771 NCBI chr 1:88,139,681...88,147,724
Ensembl chr 1:88,139,681...88,146,719 		JBrowse link
G Ugt1a5 UDP glucuronosyltransferase 1 family, polypeptide A5 increases expression EXP oltipraz results in increased expression of UGT1A5 mRNA CTD PMID:19144771 NCBI chr 1:88,093,734...88,147,724
Ensembl chr 1:88,093,734...88,146,719 		JBrowse link
G Ugt1a6a UDP glucuronosyltransferase 1 family, polypeptide A6A increases expression
multiple interactions		 EXP oltipraz results in increased expression of UGT1A6A mRNA
NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT1A6A mRNA]		 CTD PMID:22496397 NCBI chr 1:88,062,531...88,147,724
Ensembl chr 1:88,062,531...88,146,719 		JBrowse link
G Ugt1a6b UDP glucuronosyltransferase 1 family, polypeptide A6B increases expression
multiple interactions		 EXP oltipraz results in increased expression of UGT1A6 mRNA
oltipraz inhibits the reaction [Butylhydroxybutylnitrosamine results in decreased expression of UGT1A6 mRNA]		 CTD PMID:15374950 PMID:19144771 NCBI chr 1:88,030,979...88,146,720
Ensembl chr 1:88,030,974...88,146,725 		JBrowse link
G Ugt2a3 UDP glucuronosyltransferase 2 family, polypeptide A3 decreases expression EXP oltipraz results in decreased expression of UGT2A3 mRNA CTD PMID:22496397 NCBI chr 5:87,472,694...87,485,054
Ensembl chr 5:87,472,831...87,485,054 		JBrowse link
G Ugt2b1 UDP glucuronosyltransferase 2 family, polypeptide B1 decreases expression
multiple interactions		 EXP oltipraz results in decreased expression of UGT2B1 mRNA
[oltipraz co-treated with NFE2L2 protein mutant form] results in decreased expression of UGT2B1 mRNA		 CTD PMID:19144771 PMID:22496397 NCBI chr 5:87,064,498...87,074,362
Ensembl chr 5:87,064,497...87,074,389 		JBrowse link
G Ugt2b34 UDP glucuronosyltransferase 2 family, polypeptide B34 multiple interactions
increases expression		 EXP NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT2B34 mRNA] CTD PMID:22496397 NCBI chr 5:87,037,613...87,054,805
Ensembl chr 5:87,037,626...87,054,796 		JBrowse link
G Ugt2b35 UDP glucuronosyltransferase 2 family, polypeptide B35 multiple interactions EXP [oltipraz co-treated with NFE2L2 protein mutant form] results in decreased expression of UGT2B35 mRNA CTD PMID:22496397 NCBI chr 5:87,148,719...87,161,133
Ensembl chr 5:87,148,719...87,161,134 		JBrowse link
G Ugt2b36 UDP glucuronosyltransferase 2 family, polypeptide B36 multiple interactions
increases expression		 EXP NFE2L2 protein affects the reaction [oltipraz results in increased expression of UGT2B36 mRNA] CTD PMID:22496397 NCBI chr 5:87,213,786...87,240,414
Ensembl chr 5:87,213,786...87,240,414 		JBrowse link
ortho-vanillin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ugt1a10 UDP glycosyltransferase 1 family, polypeptide A10 increases glucuronidation ISO UGT1A10 protein results in increased glucuronidation of 2-vanillin CTD PMID:15117964 NCBI chr 1:87,983,133...88,147,724
Ensembl chr 1:87,983,110...88,146,726 		JBrowse link
G Ugt1a2 UDP glucuronosyltransferase 1 family, polypeptide A2 increases glucuronidation ISO UGT1A3 protein results in increased glucuronidation of 2-vanillin CTD PMID:15117964 NCBI chr 1:88,128,333...88,147,724
Ensembl chr 1:88,128,323...88,146,719 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 22194
    role 22179
      biological role 22178
        antimutagen 98
          4',5,6,7-tetramethoxyflavone 0
          4',6,7-trihydroxyisoflavone 0
          anthraflavic acid 7
          dibenzoylmethane + 22
          garbanzol 0
          oltipraz 77
          ortho-vanillin 2
          pinobanksin 0
          zinolol 0
paths to the root