Mas1 (MAS1 oncogene) - Rat Genome Database

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Gene: Mas1 (MAS1 oncogene) Mus musculus
Analyze
Symbol: Mas1
Name: MAS1 oncogene
RGD ID: 731462
MGI Page MGI
Description: Enables angiotensin receptor activity and peptide binding activity. Acts upstream of or within G protein-coupled receptor signaling pathway; positive regulation of canonical NF-kappaB signal transduction; and regulation of inflammatory response. Predicted to be located in cell surface. Predicted to be active in plasma membrane. Is expressed in several structures, including brain; extraembryonic component; gut; reproductive system; and spleen. Orthologous to human MAS1 (MAS1 proto-oncogene, G protein-coupled receptor).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: angiotensin-(1-7) receptor; M; Mas; MAS proto-oncogene; Mas receptor; Mas-1; Mas-related G protein-coupled receptor a; MasR; Mgra; proto-oncogene Mas
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,056,981 - 13,087,037 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,059,966 - 13,087,030 (-)EnsemblGRCm39 Ensembl
GRCm381712,838,841 - 12,868,150 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,841,079 - 12,868,143 (-)EnsemblGRCm38mm10GRCm38
MGSCv371713,033,871 - 13,061,009 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,684,009 - 12,711,075 (-)NCBIMGSCv36mm8
Celera1712,872,985 - 12,900,041 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
17beta-estradiol  (ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,2',4,4'-Tetrabromodiphenyl ether  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (EXP)
2,3',4,4',5-Pentachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
6-propyl-2-thiouracil  (ISO)
Ac-Ser-Asp-Lys-Pro-OH  (EXP)
aldehydo-D-glucose  (EXP,ISO)
ammonium chloride  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
benzo[a]pyrene  (ISO)
Benzo[k]fluoranthene  (EXP)
bisphenol A  (EXP,ISO)
cadmium dichloride  (EXP)
Candesartan cilexetil  (ISO)
captopril  (EXP,ISO)
chlorpyrifos  (ISO)
choline  (EXP)
clozapine  (ISO)
cyclosporin A  (ISO)
D-glucose  (EXP,ISO)
decabromodiphenyl ether  (ISO)
dimethylarsinic acid  (EXP)
diminazene diaceturate  (EXP)
ethanol  (EXP,ISO)
folic acid  (EXP)
genistein  (EXP)
glucose  (EXP,ISO)
glycidol  (ISO)
glyphosate  (EXP)
goralatide  (EXP)
haloperidol  (ISO)
hydralazine  (ISO)
indoxyl sulfate  (ISO)
isoprenaline  (ISO)
ketamine  (ISO)
L-methionine  (EXP)
lipopolysaccharide  (ISO)
lipoxin A4  (EXP)
losartan  (EXP)
N-methylnicotinate  (EXP,ISO)
olmesartan  (ISO)
oltipraz  (EXP,ISO)
paracetamol  (EXP)
paraquat  (ISO)
PCB138  (EXP)
perindopril  (ISO)
pirinixic acid  (EXP)
pregabalin  (ISO)
rotenone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
silicon dioxide  (EXP)
sodium arsenite  (EXP,ISO)
streptozocin  (EXP)
tamoxifen  (EXP)
telmisartan  (EXP,ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (ISO)
trichloroethene  (EXP,ISO)
triptonide  (EXP)
valproic acid  (EXP,ISO)
zearalenone  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
cell surface  (ISO)
membrane  (IEA)
plasma membrane  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Candesartan cilexetil protects from cardiac myosin induced cardiotoxicity via reduction of endoplasmic reticulum stress and apoptosis in rats: involvement of ACE2-Ang (1-7)-mas axis. Arumugam S, etal., Toxicology. 2012 Jan 27;291(1-3):139-45. doi: 10.1016/j.tox.2011.11.008. Epub 2011 Nov 23.
2. Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease. Brito VGB, etal., Front Pharmacol. 2020 Nov 11;11:579926. doi: 10.3389/fphar.2020.579926. eCollection 2020.
3. Chronic infusion of angiotensin receptor antagonists in the hypothalamic paraventricular nucleus prevents hypertension in a rat model of sleep apnea. da Silva AQ, etal., Brain Res. 2011 Jan 12;1368:231-8. Epub 2010 Oct 30.
4. Antiglaucomatous effects of the activation of intrinsic Angiotensin-converting enzyme 2. Foureaux G, etal., Invest Ophthalmol Vis Sci. 2013 Jun 21;54(6):4296-306. doi: 10.1167/iovs.12-11427.
5. Upregulation of hepatic angiotensin-converting enzyme 2 (ACE2) and angiotensin-(1-7) levels in experimental biliary fibrosis. Herath CB, etal., J Hepatol. 2007 Sep;47(3):387-95. Epub 2007 Apr 2.
6. Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor. Hsu CN, etal., Int J Mol Sci. 2020 Jun 26;21(12):4552. doi: 10.3390/ijms21124552.
7. Upregulation Of Angiotensin Converting Enzyme 2 In Hepatic Fibrosis By Angiotensin Converting Enzyme Inhibitors: An In Vivo And In Vitro Study. Huang ML, etal., Clin Exp Pharmacol Physiol. 2009 Sep 28.
8. Functional annotation of a full-length mouse cDNA collection. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
9. Chromosomal location of fifteen unique mouse KRAB-containing zinc finger loci. Marine JC, etal., Mamm Genome 1996 Jun;7(6):413-6.
10. Electronic Transfer of Homolog Data MGD and Homologene mouse data transfer
11. MGDs mouse GO annotations MGD data from the GO Consortium
12. MGD IEA MGD IEA
13. Renal ACE and ACE2 expression in early diabetic rats. Moon JY, etal., Nephron Exp Nephrol. 2008;110(1):e8-e16. Epub 2008 Aug 4.
14. Indoxyl sulfate downregulates expression of Mas receptor via OAT3/AhR/Stat3 pathway in proximal tubular cells. Ng HY, etal., PLoS One. 2014 Mar 10;9(3):e91517. doi: 10.1371/journal.pone.0091517. eCollection 2014.
15. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
16. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
17. The renin-angiotensin system: peptides and enzymes beyond angiotensin II. Reudelhuber TL Curr Opin Nephrol Hypertens. 2005 Mar;14(2):155-9.
18. A place in our hearts for the lowly angiotensin 1-7 peptide? Reudelhuber TL Hypertension. 2006 May;47(5):811-5. Epub 2006 Mar 6.
19. Mouse MP Annotation Import Pipeline RGD automated import pipeline
20. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
21. Angiotensin-(1-7) is an endogenous ligand for the G protein-coupled receptor Mas. Santos RA, etal., Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8258-63. Epub 2003 Jun 26.
22. Multiple mouse chromosomal loci for dynein-based motility. Vaughan KT, etal., Genomics 1996 Aug 15;36(1):29-38.
23. Sustained long term potentiation and anxiety in mice lacking the Mas protooncogene. Walther T, etal., J Biol Chem 1998 May 8;273(19):11867-73.
24. Regulation of angiotensin-(1-7) and angiotensin II type 1 receptor by telmisartan and losartan in adriamycin-induced rat heart failure. Zong WN, etal., Acta Pharmacol Sin. 2011 Nov;32(11):1345-50. doi: 10.1038/aps.2011.96. Epub 2011 Oct 3.
Additional References at PubMed
PMID:1612602   PMID:1612611   PMID:7588749   PMID:7894168   PMID:7894489   PMID:8001672   PMID:8661154   PMID:9268631   PMID:9344654   PMID:9488437   PMID:9530632   PMID:9606417  
PMID:10349636   PMID:10366627   PMID:10551889   PMID:10625868   PMID:10628734   PMID:10758111   PMID:11042159   PMID:11076861   PMID:11384784   PMID:11562346   PMID:11641723   PMID:11798184  
PMID:12477932   PMID:15809376   PMID:15950155   PMID:16141072   PMID:16141073   PMID:16157793   PMID:16204191   PMID:16567589   PMID:16602821   PMID:17196677   PMID:17616753   PMID:18025412  
PMID:18026570   PMID:18156169   PMID:18180400   PMID:18695148   PMID:19262461   PMID:19404405   PMID:20409925   PMID:20603170   PMID:20810609   PMID:20935211   PMID:21071955   PMID:21267068  
PMID:21677750   PMID:21820449   PMID:21873635   PMID:22003054   PMID:22119778   PMID:22362508   PMID:22652430   PMID:22665126   PMID:22921883   PMID:22947377   PMID:23045193   PMID:23127535  
PMID:23386129   PMID:23459756   PMID:23592774   PMID:23762470   PMID:23860355   PMID:23988828   PMID:24089374   PMID:24090483   PMID:24163134   PMID:24194600   PMID:24379178   PMID:24430551  
PMID:24583173   PMID:24588264   PMID:24756097   PMID:24799613   PMID:25169953   PMID:25222828   PMID:25249154   PMID:25339356   PMID:25625676   PMID:25650385   PMID:25676544   PMID:25809912  
PMID:25918552   PMID:26003294   PMID:26029927   PMID:26144375   PMID:26297425   PMID:26515045   PMID:26767952   PMID:26851244   PMID:27080540   PMID:27496559   PMID:27612496   PMID:27626380  
PMID:27715254   PMID:27815255   PMID:27856608   PMID:27872279   PMID:27986659   PMID:28131844   PMID:28254489   PMID:28813513   PMID:29138810   PMID:29431106   PMID:29679094   PMID:30121361  
PMID:30687131   PMID:30818065   PMID:30850299   PMID:31240418   PMID:31519791   PMID:31843339   PMID:32226394   PMID:32505463   PMID:32764118   PMID:32971570   PMID:33078906   PMID:33302427  
PMID:34212761   PMID:34661816   PMID:34874920   PMID:35014608   PMID:38097099  


Genomics

Comparative Map Data
Mas1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391713,056,981 - 13,087,037 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1713,059,966 - 13,087,030 (-)EnsemblGRCm39 Ensembl
GRCm381712,838,841 - 12,868,150 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1712,841,079 - 12,868,143 (-)EnsemblGRCm38mm10GRCm38
MGSCv371713,033,871 - 13,061,009 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361712,684,009 - 12,711,075 (-)NCBIMGSCv36mm8
Celera1712,872,985 - 12,900,041 (-)NCBICelera
Cytogenetic Map17A1NCBI
cM Map178.69NCBI
MAS1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386159,888,787 - 159,917,447 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6159,890,988 - 159,917,447 (+)EnsemblGRCh38hg38GRCh38
GRCh376160,312,020 - 160,338,479 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 366160,247,964 - 160,249,098 (+)NCBINCBI36Build 36hg18NCBI36
Build 346160,298,384 - 160,299,519NCBI
Celera6160,974,252 - 160,975,386 (+)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6157,798,119 - 157,799,253 (+)NCBIHuRef
CHM1_16160,590,238 - 160,591,372 (+)NCBICHM1_1
T2T-CHM13v2.06161,134,461 - 161,165,992 (+)NCBIT2T-CHM13v2.0
Mas1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8150,428,064 - 50,459,537 (+)NCBIGRCr8
mRatBN7.2147,879,956 - 47,911,500 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl147,880,309 - 47,911,709 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx148,571,963 - 48,603,158 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0154,557,771 - 54,588,840 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0148,647,488 - 48,678,679 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0148,076,761 - 48,108,218 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl148,077,033 - 48,108,216 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0151,644,462 - 51,675,365 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4142,154,786 - 42,185,750 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1142,157,730 - 42,188,693 (+)NCBI
Celera143,680,754 - 43,711,122 (+)NCBICelera
RH 3.4 Map1544.2RGD
Cytogenetic Map1q11NCBI
Mas1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495543920,956,862 - 20,957,839 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495543920,956,862 - 20,957,839 (-)NCBIChiLan1.0ChiLan1.0
MAS1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25179,989,640 - 180,015,684 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16177,894,549 - 177,920,364 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06157,774,098 - 157,799,983 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16162,785,263 - 162,802,530 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl6162,801,416 - 162,802,393 (+)Ensemblpanpan1.1panPan2
MAS1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1149,090,041 - 49,105,244 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl149,090,041 - 49,105,244 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha149,931,512 - 49,946,711 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0149,272,721 - 49,299,228 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl149,274,155 - 49,289,356 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1149,156,624 - 49,171,810 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0149,028,114 - 49,043,315 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0149,643,019 - 49,658,218 (+)NCBIUU_Cfam_GSD_1.0
MAS1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl17,527,861 - 7,528,838 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.117,527,566 - 7,542,110 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.219,326,523 - 9,339,701 (-)NCBISscrofa10.2Sscrofa10.2susScr3
MAS1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11387,520,860 - 87,523,523 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1387,521,947 - 87,523,098 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604059,898,097 - 59,920,293 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Mas1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248552,969,444 - 2,970,421 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248552,968,111 - 3,008,728 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Mas1
247 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1227
Count of miRNA genes:391
Interacting mature miRNAs:466
Transcripts:ENSMUST00000089015, ENSMUST00000159223, ENSMUST00000159865, ENSMUST00000161747, ENSMUST00000162119, ENSMUST00000162333, ENSMUST00000162389, ENSMUST00000165020, ENSMUST00000167152
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1357452Vtbt18_mvertebral trabecular bone trait 18 (mouse)Not determined17120975022Mouse
1302196Myaa1_mmodifier of Yaa 1 (mouse)Not determined17120975022Mouse
1357902Obq19_mobesity QTL 19 (mouse)Not determined17125662076Mouse
12910982Pifs2_mpeptide-induced fatal syndrome 2 (mouse)17126189355Mouse
1357743Lith3_mlithogenic gene 3 (mouse)Not determined17126194456Mouse
1301615Cfld3_mcystic fibrosis lung disease 3 (mouse)Not determined17127081639Mouse
1300613Pcyts4_mplasmacytoma susceptibility 4 (mouse)Not determined17127081639Mouse
1302100Circp2_mcircadian photosensitivity 2 (mouse)Not determined17129198453Mouse
12910527Nrq1a_mnoise-induced hearing loss resistant QTL 1a (mouse)17129198453Mouse
12910528Nrq1_mnoise-induced hearing loss resistant QTL 1 (mouse)17129198453Mouse
13524851Asrq8_macoustic startle response 8 (mouse)17131030170Mouse
10412276Leci2_mleukocyte endothelial cell interactions 2 (mouse)Not determined17334817537348299Mouse
1357680Idd23_minsulin dependent diabetes susceptibility 23 (mouse)Not determined17397489026401133Mouse
1300890Bhr3_mbronchial hyperresponsiveness 3 (mouse)Not determined17397489048866091Mouse
1301327Lmr7_mleishmaniasis resistance 7 (mouse)Not determined17485475227715939Mouse
4141215Mnic1_mmacronutrient intake, carbohydrate 1 (mouse)Not determined485475245670266Mouse
1300706Alan1_malloantigen response 1 (mouse)Not determined17485475246469702Mouse
1357789Kdnw3_mkidney weight 3 (mouse)Not determined17485475247885665Mouse
4141272Tfv1_mtotal food volume 1 (mouse)Not determined485475265637357Mouse
10043949Pbft7_mpercent body fat 7 (mouse)Not determined17689393640893936Mouse
4141608Phl1_mprogressive hearing loss 1 (mouse)Not determined17787584329487423Mouse
1301935Skull24_mskull morphology 24 (mouse)Not determined17858491442585149Mouse
1300787Cd8mts5_mCD8 memory T cell subset 5 (mouse)Not determined17858491442585149Mouse
1301338Lmr1_mleishmaniasis resistance 1 (mouse)Not determined171008134086996400Mouse
1302028Asbb3_mautoimmune susceptibility in C57BL/6J and BALB/c 3 (mouse)Not determined171087811944878219Mouse
4142342Lfnq4_mlung function QTL 4 (mouse)Not determined1120648439364059Mouse
4141067Hbnr2_mHeligmosomoides bakeri nematode resistance 2 (mouse)Not determined1188597145886119Mouse
14747010Mancz14_mmandible centroid size 14 (mouse)171199818445998184Mouse
4142507Obrq13_mobesity resistance QTL 13 (mouse)Not determined1219832925076769Mouse
4142150Stheal11_msoft tissue heal 11 (mouse)Not determined171228621183361768Mouse
12904946Tammq8_mtibialis anterior muscle mass QTL 8 (mouse)171245178746451787Mouse
1558807Ceat1_mchronic experimental autoimmune thyroiditis 1 (mouse)Not determined171263668226401133Mouse
13524847Asrq8a_macoustic startle response 8a (mouse)171264696146646961Mouse

Markers in Region
BB276039  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,841,118 - 12,841,241UniSTSGRCm38
MGSCv371713,033,984 - 13,034,107UniSTSGRCm37
Celera1712,873,098 - 12,873,221UniSTS
Cytogenetic Map17A1UniSTS
cM Map177.45UniSTS
cM Map178.66UniSTS
Whitehead/MRC_RH17217.03UniSTS
AW049873  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,859,673 - 12,859,759UniSTSGRCm38
MGSCv371713,052,539 - 13,052,625UniSTSGRCm37
Celera1712,891,648 - 12,891,734UniSTS
Cytogenetic Map17A1UniSTS
cM Map178.66UniSTS
cM Map177.45UniSTS
Whitehead/MRC_RH17216.02UniSTS
D17Jcs61  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381712,867,515 - 12,867,938UniSTSGRCm38
MGSCv371713,060,381 - 13,060,804UniSTSGRCm37
Celera1712,899,413 - 12,899,836UniSTS
Cytogenetic Map17A1UniSTS
cM Map17 UniSTS


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_008552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006523296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246191 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246192 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011246193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017317270 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030249524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ249895 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK015036 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK030265 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL589878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BB262893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC120790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC125537 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC144900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HG426095 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U96273 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X67735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000089015   ⟹   ENSMUSP00000086409
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,059,966 - 13,087,030 (-)Ensembl
GRCm38.p6 Ensembl1712,841,079 - 12,868,143 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159223   ⟹   ENSMUSP00000124295
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,061,205 - 13,070,794 (-)Ensembl
GRCm38.p6 Ensembl1712,842,318 - 12,851,907 (-)Ensembl
RefSeq Acc Id: ENSMUST00000159865   ⟹   ENSMUSP00000124901
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,061,348 - 13,073,928 (-)Ensembl
GRCm38.p6 Ensembl1712,842,461 - 12,855,041 (-)Ensembl
RefSeq Acc Id: ENSMUST00000161747   ⟹   ENSMUSP00000123902
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,060,002 - 13,073,347 (-)Ensembl
GRCm38.p6 Ensembl1712,841,115 - 12,854,460 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162119   ⟹   ENSMUSP00000124952
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,061,091 - 13,070,794 (-)Ensembl
GRCm38.p6 Ensembl1712,842,204 - 12,851,907 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162333   ⟹   ENSMUSP00000125108
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,060,002 - 13,073,347 (-)Ensembl
GRCm38.p6 Ensembl1712,841,115 - 12,854,460 (-)Ensembl
RefSeq Acc Id: ENSMUST00000162389   ⟹   ENSMUSP00000124879
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,061,194 - 13,070,780 (-)Ensembl
GRCm38.p6 Ensembl1712,842,307 - 12,851,893 (-)Ensembl
RefSeq Acc Id: ENSMUST00000165020   ⟹   ENSMUSP00000132300
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,060,002 - 13,067,007 (-)Ensembl
GRCm38.p6 Ensembl1712,841,115 - 12,848,120 (-)Ensembl
RefSeq Acc Id: ENSMUST00000167152   ⟹   ENSMUSP00000131341
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,060,002 - 13,073,227 (-)Ensembl
GRCm38.p6 Ensembl1712,841,115 - 12,854,340 (-)Ensembl
RefSeq Acc Id: ENSMUST00000233607   ⟹   ENSMUSP00000156871
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl1713,060,002 - 13,073,347 (-)Ensembl
GRCm38.p6 Ensembl1712,841,115 - 12,854,460 (-)Ensembl
RefSeq Acc Id: NM_008552   ⟹   NP_032578
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,057,728 - 13,087,030 (-)NCBI
GRCm381712,838,841 - 12,868,143 (-)NCBI
MGSCv371713,033,871 - 13,061,009 (-)RGD
Celera1712,872,985 - 12,900,041 (-)RGD
cM Map17 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006523293   ⟹   XP_006523356
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,070,830 (-)NCBI
GRCm381712,840,867 - 12,851,916 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006523294   ⟹   XP_006523357
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,087,037 (-)NCBI
GRCm381712,840,867 - 12,868,150 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006523296   ⟹   XP_006523359
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,056,981 - 13,070,859 (-)NCBI
GRCm381712,840,867 - 12,851,916 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246190   ⟹   XP_011244492
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,087,037 (-)NCBI
GRCm381712,840,867 - 12,868,150 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246191   ⟹   XP_011244493
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,087,037 (-)NCBI
GRCm381712,840,867 - 12,868,150 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246192   ⟹   XP_011244494
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,087,037 (-)NCBI
GRCm381712,840,867 - 12,868,150 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011246193   ⟹   XP_011244495
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,087,037 (-)NCBI
GRCm381712,840,867 - 12,868,150 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017317270   ⟹   XP_017172759
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,066,507 (-)NCBI
GRCm381712,840,867 - 12,847,620 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249523   ⟹   XP_030105383
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,071,008 (-)NCBI
GRCm381712,840,867 - 12,851,916 (-)NCBI
Sequence:
RefSeq Acc Id: XM_030249524   ⟹   XP_030105384
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm391713,059,754 - 13,070,848 (-)NCBI
GRCm381712,840,867 - 12,851,922 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_032578 (Get FASTA)   NCBI Sequence Viewer  
  XP_006523356 (Get FASTA)   NCBI Sequence Viewer  
  XP_006523357 (Get FASTA)   NCBI Sequence Viewer  
  XP_006523359 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244492 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244493 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244494 (Get FASTA)   NCBI Sequence Viewer  
  XP_011244495 (Get FASTA)   NCBI Sequence Viewer  
  XP_017172759 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105383 (Get FASTA)   NCBI Sequence Viewer  
  XP_030105384 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAB69120 (Get FASTA)   NCBI Sequence Viewer  
  AAI20791 (Get FASTA)   NCBI Sequence Viewer  
  AAI25538 (Get FASTA)   NCBI Sequence Viewer  
  AAI44901 (Get FASTA)   NCBI Sequence Viewer  
  BAB29684 (Get FASTA)   NCBI Sequence Viewer  
  BAC26865 (Get FASTA)   NCBI Sequence Viewer  
  BAC26868 (Get FASTA)   NCBI Sequence Viewer  
  CAA47964 (Get FASTA)   NCBI Sequence Viewer  
  CDG86213 (Get FASTA)   NCBI Sequence Viewer  
  EDL02043 (Get FASTA)   NCBI Sequence Viewer  
  EDL02044 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSMUSP00000086409
  ENSMUSP00000086409.4
  ENSMUSP00000123902.2
  ENSMUSP00000124295.2
  ENSMUSP00000124879.2
  ENSMUSP00000124901.2
  ENSMUSP00000124952.2
  ENSMUSP00000125108
  ENSMUSP00000125108.2
  ENSMUSP00000131341.2
  ENSMUSP00000132300
  ENSMUSP00000132300.2
  ENSMUSP00000156871.2
GenBank Protein P30554 (Get FASTA)   NCBI Sequence Viewer  
Reference Protein Sequences
RefSeq Acc Id: NP_032578   ⟸   NM_008552
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523357   ⟸   XM_006523294
- Peptide Label: isoform X1
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523359   ⟸   XM_006523296
- Peptide Label: isoform X1
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006523356   ⟸   XM_006523293
- Peptide Label: isoform X1
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244495   ⟸   XM_011246193
- Peptide Label: isoform X1
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244494   ⟸   XM_011246192
- Peptide Label: isoform X1
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244493   ⟸   XM_011246191
- Peptide Label: isoform X1
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_011244492   ⟸   XM_011246190
- Peptide Label: isoform X1
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017172759   ⟸   XM_017317270
- Peptide Label: isoform X1
- UniProtKB: O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   P30554 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030105384   ⟸   XM_030249524
- Peptide Label: isoform X1
- UniProtKB: P30554 (UniProtKB/Swiss-Prot),   O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_030105383   ⟸   XM_030249523
- Peptide Label: isoform X1
- UniProtKB: P30554 (UniProtKB/Swiss-Prot),   O35944 (UniProtKB/Swiss-Prot),   Q8BHI8 (UniProtKB/Swiss-Prot),   Q0VB49 (UniProtKB/TrEMBL),   Q9D5Q2 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSMUSP00000124295   ⟸   ENSMUST00000159223
RefSeq Acc Id: ENSMUSP00000124901   ⟸   ENSMUST00000159865
RefSeq Acc Id: ENSMUSP00000132300   ⟸   ENSMUST00000165020
RefSeq Acc Id: ENSMUSP00000156871   ⟸   ENSMUST00000233607
RefSeq Acc Id: ENSMUSP00000086409   ⟸   ENSMUST00000089015
RefSeq Acc Id: ENSMUSP00000131341   ⟸   ENSMUST00000167152
RefSeq Acc Id: ENSMUSP00000124952   ⟸   ENSMUST00000162119
RefSeq Acc Id: ENSMUSP00000124879   ⟸   ENSMUST00000162389
RefSeq Acc Id: ENSMUSP00000125108   ⟸   ENSMUST00000162333
RefSeq Acc Id: ENSMUSP00000123902   ⟸   ENSMUST00000161747
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P30554-F1-model_v2 AlphaFold P30554 1-324 view protein structure
MAS I-TASSER model P30554 1-325 view protein structure

Promoters
RGD ID:13674758
Promoter ID:EPDNEW_M21528
Type:single initiation site
Name:Mas1_1
Description:Mus musculus MAS1 oncogene , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm381712,855,039 - 12,855,099EPDNEW
RGD ID:6847420
Promoter ID:MM_ACW:21714
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Brain,   Lung
Transcripts:MAS1.DSEP07,   MAS1.ESEP07,   MAS1.FSEP07
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv361713,044,476 - 13,044,976 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:96918 AgrOrtholog
Ensembl Genes ENSMUSG00000068037 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000089015 ENTREZGENE
  ENSMUST00000089015.10 UniProtKB/Swiss-Prot
  ENSMUST00000159223.8 UniProtKB/TrEMBL
  ENSMUST00000159865.2 UniProtKB/TrEMBL
  ENSMUST00000161747.8 UniProtKB/Swiss-Prot
  ENSMUST00000162119.8 UniProtKB/TrEMBL
  ENSMUST00000162333 ENTREZGENE
  ENSMUST00000162333.8 UniProtKB/Swiss-Prot
  ENSMUST00000162389.2 UniProtKB/TrEMBL
  ENSMUST00000165020 ENTREZGENE
  ENSMUST00000165020.8 UniProtKB/Swiss-Prot
  ENSMUST00000167152.8 UniProtKB/Swiss-Prot
  ENSMUST00000233607.2 UniProtKB/Swiss-Prot
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MRGPCRFAMILY UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proto-oncogene_Mas UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17171 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:96918 ENTREZGENE
NCBI Gene 17171 ENTREZGENE
PANTHER MAS-RELATED G-PROTEIN COUPLED RECEPTOR MRG-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11334 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB MAS1 RGD
PhenoGen Mas1 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MASONCOGENE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E0CX40_MOUSE UniProtKB/TrEMBL
  E0CX57_MOUSE UniProtKB/TrEMBL
  E0CX70_MOUSE UniProtKB/TrEMBL
  E0CYD1_MOUSE UniProtKB/TrEMBL
  MAS_MOUSE UniProtKB/Swiss-Prot
  O35944 ENTREZGENE
  P30554 ENTREZGENE
  Q0VB49 ENTREZGENE, UniProtKB/TrEMBL
  Q8BHI8 ENTREZGENE
  Q9D5Q2 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary O35944 UniProtKB/Swiss-Prot
  Q8BHI8 UniProtKB/Swiss-Prot