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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Fusarenone X
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Accession:CHEBI:82577 term browser browse the term
Definition:A trichothecene that has formula C17H22O8.
Synonyms:related_synonym: Formula=C17H22O8;   Fusarenon-X;   InChI=1S/C17H22O8/c1-7-4-9-16(5-18,12(22)10(7)20)15(3)13(24-8(2)19)11(21)14(25-9)17(15)6-23-17/h4,9,11-14,18,21-22H,5-6H2,1-3H3/t9-,11-,12-,13-,14-,15-,16-,17-/m1/s1;   InChIKey=XGCUCFKWVIWWNW-UWKSZNKUSA-N;   SMILES=CC(=O)O[C@@H]1[C@@H](O)[C@H]2O[C@@H]3C=C(C)C(=O)[C@@H](O)[C@]3(CO)[C@]1(C)[C@@]21CO1
 xref: CAS:23255-69-8;   KEGG:C19583
 xref_mesh: MESH:C002469


show annotations for term's descendants           Sort by:
Fusarenone X term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ar androgen receptor decreases activity ISO fusarenon-X results in decreased activity of AR protein CTD PMID:27481073 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925 		JBrowse link
G Atf6 activating transcription factor 6 increases expression ISO fusarenon-X results in increased expression of ATF6 mRNA CTD PMID:20682335 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177 		JBrowse link
G Bad BCL2-associated agonist of cell death increases expression ISO fusarenon-X results in increased expression of BAD mRNA CTD PMID:24983900 NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823 		JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO fusarenon-X results in increased expression of BAX mRNA CTD PMID:24983900 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368 		JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression
decreases expression		 ISO fusarenon-X results in increased expression of BCL2 mRNA
fusarenon-X results in decreased expression of BCL2 mRNA		 CTD PMID:24983900 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743 		JBrowse link
G Bcl2a1 BCL2-related protein A1 increases expression ISO fusarenon-X results in increased expression of BCL2A1B mRNA CTD PMID:24983900 NCBI chr 8:89,716,914...89,724,998
Ensembl chr 8:89,716,914...89,724,998 		JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO fusarenon-X results in increased expression of BCL2L1 mRNA CTD PMID:24983900 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479 		JBrowse link
G Bcl2l2 Bcl2-like 2 increases expression ISO fusarenon-X results in increased expression of BCL2L2 mRNA CTD PMID:24983900 NCBI chr15:28,346,449...28,361,627
Ensembl chr15:28,356,807...28,361,624 		JBrowse link
G Bid BH3 interacting domain death agonist decreases expression ISO fusarenon-X results in decreased expression of BID mRNA CTD PMID:24983900 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720 		JBrowse link
G Casp4 caspase 4 increases expression ISO fusarenon-X results in increased expression of CASP4 mRNA CTD PMID:24983900 NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092 		JBrowse link
G Casp8 caspase 8 increases expression ISO fusarenon-X results in increased expression of CASP8 mRNA CTD PMID:24983900 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542 		JBrowse link
G Casp9 caspase 9 increases expression ISO fusarenon-X results in increased expression of CASP9 mRNA CTD PMID:24983900 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626 		JBrowse link
G Cck cholecystokinin increases expression ISO fusarenon-X results in increased expression of CCK protein CTD PMID:24385417 NCBI chr 8:121,153,499...121,160,194
Ensembl chr 8:121,153,500...121,160,084 		JBrowse link
G Ccl2 C-C motif chemokine ligand 2 increases expression ISO fusarenon-X results in increased expression of CCL2 mRNA CTD PMID:24793808 NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226 		JBrowse link
G Ccl7 C-C motif chemokine ligand 7 increases expression ISO fusarenon-X results in increased expression of CCL7 mRNA CTD PMID:24793808 NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303 		JBrowse link
G Cd40lg CD40 ligand decreases expression ISO fusarenon-X results in decreased expression of CD40LG mRNA CTD PMID:24983900 NCBI chr  X:135,127,052...135,138,768
Ensembl chr  X:135,126,969...135,138,306 		JBrowse link
G Cxcl2 C-X-C motif chemokine ligand 2 increases expression ISO fusarenon-X results in increased expression of CXCL2 mRNA CTD PMID:24793808 NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075 		JBrowse link
G Eif2a eukaryotic translation initiation factor 2A increases phosphorylation ISO fusarenon-X results in increased phosphorylation of EIF2A protein CTD PMID:20682335 NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068 		JBrowse link
G Fas Fas cell surface death receptor increases expression ISO fusarenon-X results in increased expression of FAS mRNA CTD PMID:24983900 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591 		JBrowse link
G Faslg Fas ligand decreases expression ISO fusarenon-X results in decreased expression of FASL mRNA CTD PMID:24983900 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215 		JBrowse link
G Gzmb granzyme B increases expression ISO fusarenon-X results in increased expression of GZMB mRNA CTD PMID:24983900 NCBI chr15:30,343,352...30,346,814
Ensembl chr15:30,173,603...30,346,814 		JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 decreases expression ISO fusarenon-X results in decreased expression of HSPA5 mRNA CTD PMID:20682335 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891 		JBrowse link
G Il1b interleukin 1 beta increases expression ISO fusarenon-X results in increased expression of IL1B mRNA CTD PMID:24793808 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415 		JBrowse link
G Il6 interleukin 6 increases expression ISO fusarenon-X results in increased expression of IL6 mRNA CTD PMID:24793808 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Irf2 interferon regulatory factor 2 increases expression ISO fusarenon-X results in increased expression of IRF2 mRNA CTD PMID:24983900 NCBI chr16:45,439,215...45,550,054
Ensembl chr16:45,439,225...45,550,024 		JBrowse link
G Map3k14 mitogen-activated protein kinase kinase kinase 14 increases expression ISO fusarenon-X results in increased expression of MAP3K14 mRNA CTD PMID:24983900 NCBI chr10:88,165,349...88,215,558
Ensembl chr10:88,165,351...88,215,523 		JBrowse link
G Nfkbie NFKB inhibitor epsilon increases expression ISO fusarenon-X results in increased expression of NFKBIE mRNA CTD PMID:24983900 NCBI chr 9:15,443,600...15,450,437
Ensembl chr 9:15,436,941...15,450,437 		JBrowse link
G Ngf nerve growth factor increases expression ISO fusarenon-X results in increased expression of NGF mRNA CTD PMID:24983900 NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452 		JBrowse link
G Ngfr nerve growth factor receptor decreases expression ISO fusarenon-X results in decreased expression of NGFR mRNA CTD PMID:24983900 NCBI chr10:80,515,287...80,533,518
Ensembl chr10:80,515,299...80,533,518 		JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 decreases expression ISO fusarenon-X results in decreased expression of NR3C1 mRNA CTD PMID:24983900 NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375 		JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases activity ISO fusarenon-X results in decreased activity of PPARG protein CTD PMID:27481073 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468 		JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 increases expression ISO fusarenon-X results in increased expression of PTGS2 mRNA CTD PMID:14514436 NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188 		JBrowse link
G Tnf tumor necrosis factor increases expression ISO fusarenon-X results in increased expression of TNF mRNA CTD PMID:24793808 PMID:24983900 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629 		JBrowse link
G Tnfrsf10b TNF receptor superfamily member 10b decreases expression ISO fusarenon-X results in decreased expression of TNFRSF10B mRNA CTD PMID:24983900 NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467 		JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B increases expression ISO fusarenon-X results in increased expression of TNFRSF1B mRNA CTD PMID:24983900 NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206 		JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO fusarenon-X results in increased expression of TNFSF10 mRNA CTD PMID:24983900 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135 		JBrowse link
G Tp53 tumor protein p53 increases expression ISO fusarenon-X results in increased expression of TRP53 mRNA CTD PMID:24983900 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524 		JBrowse link
G Tp63 tumor protein p63 decreases expression ISO fusarenon-X results in decreased expression of TRP63 mRNA CTD PMID:24983900 NCBI chr11:74,838,858...75,049,764
Ensembl chr11:74,838,859...75,049,398 		JBrowse link
G Tp73 tumor protein p73 increases expression ISO fusarenon-X results in increased expression of TRP73 mRNA CTD PMID:24983900 NCBI chr 5:164,621,377...164,703,958
Ensembl chr 5:164,621,377...164,681,128 		JBrowse link
G Traf1 TNF receptor-associated factor 1 increases expression ISO fusarenon-X results in increased expression of TRAF1 mRNA CTD PMID:24983900 NCBI chr 3:18,222,024...18,242,163
Ensembl chr 3:18,222,054...18,241,807 		JBrowse link
G Traf3 Tnf receptor-associated factor 3 decreases expression ISO fusarenon-X results in decreased expression of TRAF3 mRNA CTD PMID:24983900 NCBI chr 6:130,199,696...130,307,168
Ensembl chr 6:130,206,484...130,305,481 		JBrowse link
G Traf6 TNF receptor associated factor 6 increases expression ISO fusarenon-X results in increased expression of TRAF6 mRNA CTD PMID:24983900 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507 		JBrowse link
G Xiap X-linked inhibitor of apoptosis decreases expression ISO fusarenon-X results in decreased expression of XIAP mRNA CTD PMID:24983900 NCBI chr  X:120,890,537...120,938,413
Ensembl chr  X:120,897,907...120,934,700 		JBrowse link
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  CHEBI ontology 19844
    role 19820
      biological role 19818
        poison 18614
          toxin 15979
            mycotoxin 12018
              trichothecene 1527
                Fusarenone X 43
Path 2
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  CHEBI ontology 19844
    subatomic particle 19842
      composite particle 19842
        hadron 19842
          baryon 19842
            nucleon 19809
              atomic nucleus 19842
                atom 19842
                  main group element atom 19792
                    p-block element atom 19792
                      carbon group element atom 19738
                        carbon atom 19734
                          organic molecular entity 19734
                            organic molecule 19687
                              organic cyclic compound 19498
                                organic heterocyclic compound 18870
                                  organic heteromonocyclic compound 17796
                                    saturated organic heteromonocyclic parent 11296
                                      oxirane 11276
                                        epoxide 11275
                                          trichothecene 1527
                                            Fusarenone X 43
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