Traf1 (TNF receptor-associated factor 1) - Rat Genome Database

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Gene: Traf1 (TNF receptor-associated factor 1) Rattus norvegicus
Analyze
Symbol: Traf1
Name: TNF receptor-associated factor 1
RGD ID: 1596290
Description: Predicted to enable enzyme binding activity; identical protein binding activity; and tumor necrosis factor receptor binding activity. Predicted to be involved in protein K63-linked ubiquitination; regulation of signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and cytoplasmic side of plasma membrane. Orthologous to human TRAF1 (TNF receptor associated factor 1); PARTICIPATES IN tumor necrosis factor mediated signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; arsenous acid; atrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC687813; similar to Tnf receptor-associated factor 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8338,607,707 - 38,639,641 (-)NCBIGRCr8
mRatBN7.2318,222,024 - 18,242,163 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl318,222,054 - 18,241,807 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx321,290,164 - 21,306,516 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0329,875,188 - 29,891,540 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0328,129,049 - 28,145,401 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0314,003,340 - 14,022,955 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl314,003,340 - 14,022,672 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0319,323,420 - 19,343,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera312,939,551 - 12,955,889 (-)NCBICelera
Cytogenetic Map3p11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-demecolcine  (ISO)
1'-acetoxychavicol acetate  (ISO)
1,2-dichloroethane  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
4-nitrophenol  (ISO)
4-nitroquinoline N-oxide  (ISO)
6-propyl-2-thiouracil  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
aristolochic acid A  (ISO)
arsenous acid  (EXP,ISO)
atrazine  (EXP)
bathocuproine disulfonic acid  (ISO)
benzo[a]pyrene  (ISO)
benzoates  (ISO)
berberine  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
calcitriol  (ISO)
cannabidiol  (ISO)
carbon nanotube  (ISO)
carmustine  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cholesterol  (EXP)
cisplatin  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
delta-tocotrienol  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diarsenic trioxide  (EXP,ISO)
diiodine  (ISO)
dimethylarsinic acid  (ISO)
dioscin  (ISO)
dioxygen  (ISO)
doxorubicin  (ISO)
endosulfan  (EXP)
folic acid  (ISO)
formaldehyde  (ISO)
Fusarenone X  (ISO)
gemcitabine  (ISO)
guggulsterone  (ISO)
indole-3-methanol  (ISO)
ionomycin  (ISO)
irinotecan  (ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
lonafarnib  (ISO)
methotrexate  (ISO)
methyl methanesulfonate  (ISO)
methylarsonic acid  (ISO)
N-nitrosodiethylamine  (ISO)
nickel sulfate  (ISO)
ozone  (ISO)
p-menthan-3-ol  (ISO)
paclitaxel  (ISO)
paracetamol  (EXP)
paraquat  (ISO)
parthenolide  (ISO)
pemetrexed  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pyrrolidine dithiocarbamate  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
Rhein  (ISO)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
serpentine asbestos  (ISO)
silicon dioxide  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
succimer  (ISO)
sulforaphane  (ISO)
sunitinib  (ISO)
tert-butyl hydroperoxide  (ISO)
theophylline  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
triptonide  (ISO)
trovafloxacin  (ISO)
urethane  (ISO)
vincristine  (ISO)
vinorelbine  (ISO)
vorinostat  (ISO)
zerumbone  (ISO)
zinc atom  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8069916   PMID:10692572   PMID:11279055   PMID:11728344   PMID:12477932   PMID:14743216   PMID:25416956   PMID:27107012   PMID:29657313  


Genomics

Comparative Map Data
Traf1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8338,607,707 - 38,639,641 (-)NCBIGRCr8
mRatBN7.2318,222,024 - 18,242,163 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl318,222,054 - 18,241,807 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx321,290,164 - 21,306,516 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0329,875,188 - 29,891,540 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0328,129,049 - 28,145,401 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0314,003,340 - 14,022,955 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl314,003,340 - 14,022,672 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0319,323,420 - 19,343,090 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Celera312,939,551 - 12,955,889 (-)NCBICelera
Cytogenetic Map3p11NCBI
TRAF1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389120,902,393 - 120,929,171 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9120,902,393 - 120,929,173 (-)EnsemblGRCh38hg38GRCh38
GRCh379123,664,671 - 123,691,449 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369122,704,493 - 122,728,994 (-)NCBINCBI36Build 36hg18NCBI36
Build 349120,744,225 - 120,768,727NCBI
Celera994,313,094 - 94,339,873 (-)NCBICelera
Cytogenetic Map9q33.2NCBI
HuRef993,282,121 - 93,308,908 (-)NCBIHuRef
CHM1_19123,811,798 - 123,838,569 (-)NCBICHM1_1
T2T-CHM13v2.09133,098,529 - 133,125,751 (-)NCBIT2T-CHM13v2.0
Traf1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39234,831,762 - 34,851,784 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl234,831,762 - 34,851,784 (-)EnsemblGRCm39 Ensembl
GRCm38234,941,750 - 34,961,812 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl234,941,750 - 34,961,772 (-)EnsemblGRCm38mm10GRCm38
MGSCv37234,798,778 - 34,817,292 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36234,765,267 - 34,783,781 (-)NCBIMGSCv36mm8
Celera234,637,578 - 34,656,091 (-)NCBICelera
Cytogenetic Map2BNCBI
cM Map223.13NCBI
Traf1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554197,121,382 - 7,137,763 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554197,117,869 - 7,145,274 (+)NCBIChiLan1.0ChiLan1.0
TRAF1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21118,414,427 - 18,443,728 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1918,416,759 - 18,444,504 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0992,030,205 - 92,056,776 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19120,376,592 - 120,403,185 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9120,376,592 - 120,402,948 (-)Ensemblpanpan1.1panPan2
TRAF1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11173,920,729 - 73,939,644 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1173,927,007 - 73,937,655 (-)EnsemblCanFam3.1canFam3CanFam3.1
Traf1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947189,581,356 - 189,600,750 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364879,349,483 - 9,367,045 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364879,349,883 - 9,368,946 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TRAF1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1260,949,111 - 260,973,709 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11260,948,191 - 260,973,978 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21293,049,905 - 293,062,803 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TRAF1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11218,647,131 - 18,672,685 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1218,650,190 - 18,670,643 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366603524,341,903 - 24,367,955 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Traf1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462476014,424,157 - 14,446,084 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462476014,423,735 - 14,445,033 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Traf1
180 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:128
Count of miRNA genes:103
Interacting mature miRNAs:113
Transcripts:ENSRNOT00000072400
Prediction methods:Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70202Alc19Alcohol consumption QTL 192.5drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)3127494778Rat
631679Cm10Cardiac mass QTL 107.340.0001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3131158234Rat
631831Alc8Alcohol consumption QTL 82.7consumption behavior trait (VT:0002069)calculated ethanol drink intake rate (CMO:0001615)3133230976Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)diastolic blood pressure (CMO:0000005)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)systolic blood pressure (CMO:0000004)3133278763Rat
61468Bp15Blood pressure QTL 154.4blood pressure trait (VT:0000183)pulse pressure (CMO:0000292)3133278763Rat
631545Bp85Blood pressure QTL 853.1arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3133278763Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
2312664Scl62Serum cholesterol level QTL 620.05blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)3138710544Rat
631568Bp92Blood pressure QTL 922.20.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3139874793Rat
2290452Scl56Serum cholesterol level QTL 562.26blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)3191609953Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
70203Gcr2Gastric cancer resistance QTL 22.6stomach morphology trait (VT:0000470)stomach tumor susceptibility score (CMO:0002043)3865816227494778Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
6893363Bw105Body weight QTL 1052.60.0036body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)31077870450302886Rat
70191BpQTLcluster4Blood pressure QTL cluster 43arterial blood pressure trait (VT:2000000)absolute change in systolic blood pressure (CMO:0000607)31077870450302886Rat
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1558657Cm43Cardiac mass QTL 436.60.0000000293heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat
1358885Bp251Blood pressure QTL 2513.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
1358888Bp264Blood pressure QTL 2644.43arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)314489145121056321Rat
2298542Neuinf11Neuroinflammation QTL 113.9nervous system integrity trait (VT:0010566)spinal cord complement component 1, q subcomponent, B chain mRNA level (CMO:0002126)31500542276927699Rat
631676Cm8Cardiac mass QTL 87.030.0001aorta mass (VT:0002845)aorta weight (CMO:0000076)31695470861954708Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)heart rate (CMO:0000002)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat
634306Bp140Blood pressure QTL 1403.30.0013arterial blood pressure trait (VT:2000000)body weight (CMO:0000012)31737470335528639Rat

Markers in Region
RH143117  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2318,236,219 - 18,236,452 (+)MAPPERmRatBN7.2
Rnor_6.0314,017,024 - 14,017,256NCBIRnor6.0
Rnor_5.0319,337,104 - 19,337,336UniSTSRnor5.0
RGSC_v3.4313,968,193 - 13,968,425UniSTSRGSC3.4
Celera312,953,819 - 12,954,051UniSTS
RH 3.4 Map3163.9UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 2 12 19 12 7
Low 1 43 45 41 41 8 11 60 35 29 4 8
Below cutoff 14

Sequence


RefSeq Acc Id: ENSRNOT00000072400   ⟹   ENSRNOP00000064786
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl314,003,340 - 14,019,204 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092918   ⟹   ENSRNOP00000076012
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl314,008,772 - 14,019,209 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000092980   ⟹   ENSRNOP00000076070
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl318,222,054 - 18,241,807 (-)Ensembl
Rnor_6.0 Ensembl314,003,346 - 14,022,672 (-)Ensembl
RefSeq Acc Id: NM_001271240   ⟹   NP_001258169
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8338,619,506 - 38,635,770 (-)NCBI
mRatBN7.2318,222,024 - 18,238,290 (-)NCBI
Rnor_6.0314,003,340 - 14,019,204 (-)NCBI
Rnor_5.0319,323,420 - 19,343,090 (-)NCBI
Celera312,939,551 - 12,955,889 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006233999   ⟹   XP_006234061
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8338,607,707 - 38,639,529 (-)NCBI
mRatBN7.2318,222,030 - 18,241,955 (-)NCBI
Rnor_6.0314,003,346 - 14,022,955 (-)NCBI
Rnor_5.0319,323,420 - 19,343,090 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039105872   ⟹   XP_038961800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8338,607,707 - 38,639,641 (-)NCBI
mRatBN7.2318,222,030 - 18,242,163 (-)NCBI
RefSeq Acc Id: XM_039105873   ⟹   XP_038961801
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8338,607,707 - 38,639,454 (-)NCBI
mRatBN7.2318,222,030 - 18,241,957 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001258169 (Get FASTA)   NCBI Sequence Viewer  
  XP_006234061 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961800 (Get FASTA)   NCBI Sequence Viewer  
  XP_038961801 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI58697 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000076070
  ENSRNOP00000076070.2
RefSeq Acc Id: NP_001258169   ⟸   NM_001271240
- UniProtKB: A0A1B0GWY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006234061   ⟸   XM_006233999
- Peptide Label: isoform X1
- UniProtKB: A0A1B0GWY7 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000064786   ⟸   ENSRNOT00000072400
RefSeq Acc Id: ENSRNOP00000076070   ⟸   ENSRNOT00000092980
RefSeq Acc Id: ENSRNOP00000076012   ⟸   ENSRNOT00000092918
RefSeq Acc Id: XP_038961800   ⟸   XM_039105872
- Peptide Label: isoform X1
- UniProtKB: A0A1B0GWY7 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038961801   ⟸   XM_039105873
- Peptide Label: isoform X1
- UniProtKB: A0A1B0GWY7 (UniProtKB/TrEMBL)
Protein Domains
MATH

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-M0R5V5-F1-model_v2 AlphaFold M0R5V5 1-409 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692011
Promoter ID:EPDNEW_R2536
Type:single initiation site
Name:Traf1_2
Description:TNF receptor-associated factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2537  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0314,019,208 - 14,019,268EPDNEW
RGD ID:13692015
Promoter ID:EPDNEW_R2537
Type:single initiation site
Name:Traf1_1
Description:TNF receptor-associated factor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_R2536  
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0314,022,686 - 14,022,746EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1596290 AgrOrtholog
BioCyc Gene G2FUF-50068 BioCyc
Ensembl Genes ENSRNOG00000048914 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000092980.2 UniProtKB/TrEMBL
Gene3D-CATH 1.20.5.110 UniProtKB/TrEMBL
InterPro MATH UniProtKB/TrEMBL
  TNF_rcpt--assoc_TRAF UniProtKB/TrEMBL
  TRAF-like UniProtKB/TrEMBL
  TRAF_BIRC3-bd UniProtKB/TrEMBL
  TRAF_MEP1_MATH_dom UniProtKB/TrEMBL
NCBI Gene 687813 ENTREZGENE
PANTHER PTHR10131 UniProtKB/TrEMBL
  PTHR10131:SF96 UniProtKB/TrEMBL
Pfam TRAF-mep_MATH UniProtKB/TrEMBL
  TRAF_BIRC3_bd UniProtKB/TrEMBL
PhenoGen Traf1 PhenoGen
PIRSF TRAF UniProtKB/TrEMBL
PROSITE MATH UniProtKB/TrEMBL
RatGTEx ENSRNOG00000048914 RatGTEx
SMART MATH UniProtKB/TrEMBL
Superfamily-SCOP TRAF domain-like UniProtKB/TrEMBL
UniProt A0A1B0GWY7 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-16 Traf1  TNF receptor-associated factor 1  LOC687813  similar to Tnf receptor-associated factor 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC687813  similar to Tnf receptor-associated factor 1      Symbol and Name status set to provisional 70820 PROVISIONAL