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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:Dimethyl phthalate
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Accession:CHEBI:4609 term browser browse the term
Definition:A phthalate ester that has formula C10H10O4.
Synonyms:related_synonym: Formula=C10H10O4;   InChI=1S/C10H10O4/c1-13-9(11)7-5-3-4-6-8(7)10(12)14-2/h3-6H,1-2H3;   InChIKey=NIQCNGHVCWTJSM-UHFFFAOYSA-N;   SMILES=COC(=O)c1ccccc1C(=O)OC
 xref: CAS:131-11-3;   Drug_Central:4771;   KEGG:C11233
 xref_mesh: MESH:C024629
 xref: PPDB:2989;   VSDB:2989



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Dimethyl phthalate term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Afp alpha-fetoprotein affects binding EXP dimethyl phthalate binds to AFP protein CTD PMID:23013281 PMID:25349334 NCBI chr14:17,573,412...17,591,476
Ensembl chr14:17,573,412...17,591,480
JBrowse link
G Ar androgen receptor multiple interactions ISO dimethyl phthalate analog inhibits the reaction [Dihydrotestosterone binds to and results in increased activity of AR protein]; dimethyl phthalate inhibits the reaction [Dihydrotestosterone results in increased activity of AR protein] CTD PMID:20943248 PMID:28571686 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Bak1 BCL2-antagonist/killer 1 increases expression EXP dimethyl phthalate results in increased expression of BAK1 mRNA CTD PMID:35598668 NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression EXP dimethyl phthalate results in increased expression of BAX mRNA CTD PMID:35598668 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator increases expression EXP dimethyl phthalate results in increased expression of BCL2 mRNA CTD PMID:35598668 NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743
JBrowse link
G Bid BH3 interacting domain death agonist increases expression EXP dimethyl phthalate results in increased expression of BID mRNA CTD PMID:35598668 NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720
JBrowse link
G Casp2 caspase 2 increases expression EXP dimethyl phthalate results in increased expression of CASP2 mRNA CTD PMID:35598668 NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379
JBrowse link
G Casp3 caspase 3 increases expression EXP dimethyl phthalate results in increased expression of CASP3 mRNA CTD PMID:35598668 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 increases expression EXP dimethyl phthalate results in increased expression of CASP7 mRNA CTD PMID:35598668 NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casp8 caspase 8 increases expression EXP dimethyl phthalate results in increased expression of CASP8 mRNA CTD PMID:35598668 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 increases expression EXP dimethyl phthalate results in increased expression of CYP11A1 mRNA CTD PMID:26472102 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 decreases activity EXP dimethyl phthalate results in decreased activity of CYP1A2 protein CTD PMID:27432241 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp2b1 cytochrome P450, family 2, subfamily b, polypeptide 1 decreases activity EXP dimethyl phthalate results in decreased activity of CYP2B1 protein CTD PMID:27432241 NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052
JBrowse link
G Fadd Fas associated via death domain increases expression EXP dimethyl phthalate results in increased expression of FADD mRNA CTD PMID:35598668 NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653
JBrowse link
G Fas Fas cell surface death receptor increases expression EXP dimethyl phthalate results in increased expression of FAS mRNA CTD PMID:35598668 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Faslg Fas ligand increases expression EXP dimethyl phthalate results in increased expression of FASLG mRNA CTD PMID:35598668 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Ifng interferon gamma decreases expression EXP dimethyl phthalate results in decreased expression of IFNG protein CTD PMID:35598668 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Igf1 insulin-like growth factor 1 decreases expression EXP dimethyl phthalate results in decreased expression of IGF1 mRNA CTD PMID:26472102 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Il4 interleukin 4 decreases expression EXP dimethyl phthalate results in decreased expression of IL4 protein CTD PMID:35598668 NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
JBrowse link
G Il6 interleukin 6 decreases expression EXP dimethyl phthalate results in decreased expression of IL6 protein CTD PMID:35598668 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Msh2 mutS homolog 2 decreases expression EXP dimethyl phthalate results in decreased expression of MSH2 mRNA CTD PMID:26472102 NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938
JBrowse link
G Myocd myocardin decreases expression EXP dimethyl phthalate results in decreased expression of MYOCD mRNA CTD PMID:26472102 NCBI chr10:49,833,219...49,928,806
Ensembl chr10:49,836,641...49,927,627
JBrowse link
G Nr1i3 nuclear receptor subfamily 1, group I, member 3 affects binding ISO dimethyl phthalate binds to NR1I3 protein CTD PMID:25938866 NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha affects binding ISO dimethyl phthalate binds to PPARA protein CTD PMID:23843199 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Ppard peroxisome proliferator-activated receptor delta affects binding ISO dimethyl phthalate binds to PPARB protein CTD PMID:23843199 NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma affects binding ISO dimethyl phthalate binds to PPARG protein CTD PMID:23843199 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rxra retinoid X receptor alpha affects binding ISO dimethyl phthalate binds to RXRA protein CTD PMID:23843199 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Rxrb retinoid X receptor beta affects binding ISO dimethyl phthalate binds to RXRB protein CTD PMID:23843199 NCBI chr20:4,816,813...4,823,267
Ensembl chr20:4,816,815...4,828,773
JBrowse link
G Rxrg retinoid X receptor gamma affects binding ISO dimethyl phthalate binds to RXRG protein CTD PMID:23843199 NCBI chr13:79,743,430...79,785,173
Ensembl chr13:79,743,563...79,785,167
JBrowse link
G Scarb1 scavenger receptor class B, member 1 decreases expression EXP dimethyl phthalate results in decreased expression of SCARB1 mRNA CTD PMID:26472102 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression EXP dimethyl phthalate results in decreased expression of SOD1 protein CTD PMID:35598668 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Star steroidogenic acute regulatory protein decreases expression EXP dimethyl phthalate results in decreased expression of STAR mRNA CTD PMID:26472102 NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672
JBrowse link

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  CHEBI ontology 19808
    role 19784
      application 19627
        fuel 11339
          methanol 3959
            methyl ester 3905
              Dimethyl phthalate 32
Path 2
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  CHEBI ontology 19808
    subatomic particle 19806
      composite particle 19806
        hadron 19806
          baryon 19806
            nucleon 19806
              atomic nucleus 19806
                atom 19806
                  main group element atom 19756
                    p-block element atom 19756
                      carbon group element atom 19705
                        carbon atom 19702
                          organic molecular entity 19702
                            heteroorganic entity 19460
                              organochalcogen compound 19224
                                organooxygen compound 19141
                                  carbon oxoacid 18612
                                    carboxylic acid 18609
                                      aromatic carboxylic acid 12598
                                        benzoic acids 12575
                                          benzenedicarboxylic acid 8592
                                            phthalic acid 8354
                                              phthalate ester 8354
                                                Dimethyl phthalate 32
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