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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:Aurin
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Accession:CHEBI:34544 term browser browse the term
Definition:A diarylmethane that has formula C19H14O3.
Synonyms:related_synonym: Formula=C19H14O3;   InChI=1S/C19H14O3/c20-16-7-1-13(2-8-16)19(14-3-9-17(21)10-4-14)15-5-11-18(22)12-6-15/h1-12,20-21H;   InChIKey=FYEHYMARPSSOBO-UHFFFAOYSA-N;   SMILES=Oc1ccc(cc1)C(c1ccc(O)cc1)=C1C=CC(=O)C=C1
 xref: CAS:603-45-2;   KEGG:C14213
 xref_mesh: MESH:C017037


show annotations for term's descendants           Sort by:
Aurin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor decreases expression EXP aurin results in decreased expression of AHR protein CTD PMID:25477506 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AR androgen receptor affects binding ISO aurin binds to AR protein CTD PMID:14565775 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A increases expression EXP aurin results in increased expression of CDKN1A mRNA CTD PMID:25477506 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,337 		JBrowse link
G CRYAB crystallin alpha B increases expression EXP aurin results in increased expression of CRYAB mRNA CTD PMID:25477506 NCBI chr11:111,908,564...111,923,740
Ensembl chr11:111,908,564...111,923,722 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 decreases expression EXP aurin results in decreased expression of CXCL10 mRNA CTD PMID:25477506 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 decreases expression EXP aurin results in decreased expression of CYP1A1 mRNA CTD PMID:25477506 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 increases expression EXP aurin results in increased expression of DDIT3 mRNA; aurin results in increased expression of DDIT3 protein CTD PMID:25477506 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G DNAJA1 DnaJ heat shock protein family (Hsp40) member A1 increases expression EXP aurin results in increased expression of DNAJA1 mRNA CTD PMID:25477506 NCBI chr 9:33,025,273...33,039,907
Ensembl chr 9:33,025,273...33,039,907 		JBrowse link
G DNAJB4 DnaJ heat shock protein family (Hsp40) member B4 increases expression EXP aurin results in increased expression of DNAJB4 mRNA CTD PMID:25477506 NCBI chr 1:77,979,175...78,017,964
Ensembl chr 1:77,979,175...78,017,964 		JBrowse link
G EGR1 early growth response 1 increases expression EXP aurin results in increased expression of EGR1 mRNA CTD PMID:25477506 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 increases phosphorylation EXP aurin results in increased phosphorylation of EIF2AK3 protein CTD PMID:25477506 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G EIF2S1 eukaryotic translation initiation factor 2 subunit alpha increases phosphorylation EXP aurin results in increased phosphorylation of EIF2S1 protein CTD PMID:25477506 NCBI chr14:67,360,328...67,386,516
Ensembl chr14:67,360,328...67,386,516 		JBrowse link
G FKBP5 FKBP prolyl isomerase 5 multiple interactions EXP aurin inhibits the reaction [Dexamethasone results in increased expression of FKBP5 mRNA]; aurin inhibits the reaction [NR3C1 protein results in increased expression of FKBP5 mRNA] CTD PMID:19255438 NCBI chr 6:35,573,590...35,728,583
Ensembl chr 6:35,573,585...35,728,583 		JBrowse link
G GADD45A growth arrest and DNA damage inducible alpha increases expression EXP aurin results in increased expression of GADD45A mRNA CTD PMID:25477506 NCBI chr 1:67,685,201...67,688,334
Ensembl chr 1:67,685,201...67,688,334 		JBrowse link
G GDF15 growth differentiation factor 15 increases expression EXP aurin results in increased expression of GDF15 mRNA CTD PMID:25477506 NCBI chr19:18,386,158...18,389,176
Ensembl chr19:18,374,731...18,389,176 		JBrowse link
G HMOX1 heme oxygenase 1 increases expression EXP aurin results in increased expression of HMOX1 mRNA; aurin results in increased expression of HMOX1 protein CTD PMID:25477506 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSF1 heat shock transcription factor 1 affects localization EXP aurin affects the localization of HSF1 protein CTD PMID:25477506 NCBI chr 8:144,291,604...144,314,720
Ensembl chr 8:144,291,591...144,314,720 		JBrowse link
G HSPA1A heat shock protein family A (Hsp70) member 1A increases expression EXP aurin results in increased expression of HSPA1A mRNA; aurin results in increased expression of HSPA1A protein CTD PMID:25477506 NCBI chr 6:31,815,543...31,817,942
Ensembl chr 6:31,815,543...31,817,946 		JBrowse link
G HSPA1L heat shock protein family A (Hsp70) member 1 like increases expression EXP aurin results in increased expression of HSPA1L mRNA CTD PMID:25477506 NCBI chr 6:31,809,619...31,815,283
Ensembl chr 6:31,809,619...31,815,283 		JBrowse link
G HSPA6 heat shock protein family A (Hsp70) member 6 increases expression EXP aurin results in increased expression of HSPA6 mRNA CTD PMID:25477506 NCBI chr 1:161,524,540...161,526,894
Ensembl chr 1:161,524,540...161,526,894 		JBrowse link
G HSPB1 heat shock protein family B (small) member 1 increases expression EXP aurin results in increased expression of HSPB1 mRNA CTD PMID:25477506 NCBI chr 7:76,302,673...76,304,292
Ensembl chr 7:76,302,673...76,304,295 		JBrowse link
G HSPH1 heat shock protein family H (Hsp110) member 1 increases expression EXP aurin results in increased expression of HSPH1 mRNA CTD PMID:25477506 NCBI chr13:31,134,973...31,162,388
Ensembl chr13:31,134,973...31,162,388 		JBrowse link
G IL1B interleukin 1 beta decreases expression EXP aurin results in decreased expression of IL1B mRNA CTD PMID:25477506 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL6 interleukin 6 decreases expression EXP aurin results in decreased expression of IL6 mRNA CTD PMID:25477506 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 decreases activity
multiple interactions		 EXP aurin results in decreased activity of NR3C1 protein
aurin inhibits the reaction [NR3C1 protein results in increased expression of FKBP5 mRNA]		 CTD PMID:19255438 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 increases expression
increases response to substance		 EXP aurin results in increased expression of PMAIP1 mRNA; aurin results in increased expression of PMAIP1 protein
PMAIP1 protein results in increased susceptibility to aurin		 CTD PMID:25477506 NCBI chr18:59,899,996...59,904,305
Ensembl chr18:59,899,996...59,904,305 		JBrowse link
G SERPINE1 serpin family E member 1 increases expression EXP aurin results in increased expression of SERPINE1 mRNA CTD PMID:25477506 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SHBG sex hormone binding globulin affects binding EXP aurin binds to SHBG protein CTD PMID:25349334 NCBI chr17:7,614,064...7,633,372
Ensembl chr17:7,613,946...7,633,382 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 26050
    chemical entity 26029
      group 25892
        polyatomic entity 25892
          molecule 25278
            cyclic compound 24288
              organic cyclic compound 24287
                organic aromatic compound 23926
                  diarylmethane 9619
                    Aurin 28
Path 2
Term Annotations click to browse term
  CHEBI ontology 26050
    subatomic particle 26025
      composite particle 26025
        hadron 26025
          baryon 26025
            nucleon 26025
              atomic nucleus 26025
                atom 26025
                  main group element atom 25850
                    p-block element atom 25850
                      p-block molecular entity 25845
                        carbon group molecular entity 25447
                          organic molecular entity 25405
                            organic molecule 25233
                              organic cyclic compound 24287
                                organic aromatic compound 23926
                                  diarylmethane 9619
                                    Aurin 28
paths to the root