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Wnt family

In mammals there are 19 Wnt proteins. Some Wnt members are thought to be specific to the canonical or beta-catenin-dependent pathway (Wnt1, Wnt3a or Wnt8) and other to activate the non-canonical beta-catenin-independent pathway (Wnt5a or Wnt11). Recent results suggest that the outcome of Wnt signaling might be related to specific receptor or other partner interactions  as well as patterns of expression. The Wnt family members are listed with aliases in parentheses, full names and links to report pages:

 

Wnt1 (wingless-type MMTV integration site family, member 1) – Wnt family member 1
Wnt2 (wingless-type MMTV integration site family, member 2) – Wnt family member 2
Wnt2b (wingless-type MMTV integration site family, member 2b) – Wnt family member 2B
Wnt3 (wingless-type MMTV integration site family, member 3) – Wnt family member 3
Wnt3a (wingless-type MMTV integration site family, member 3A) – Wnt family member 3A

Wnt4 (wingless-type MMTV integration site 4) – Wnt family member 4
Wnt5a (wingless-type MMTV integration site family, member 5A) – Wnt family member 5A
Wnt5b (wingless-type MMTV integration site family, member 5B) – Wnt family member 5B
Wnt6 (wingless-type MMTV integration site family, member 6) – Wnt family member 6

Wnt7a (wingless-type MMTV integration site family,  7A) – Wnt family member 7A

Wnt7b (wingless-type MMTV integration site family, member 7B) – Wnt family member 7B
Wnt8a (wingless-type MMTV integration site family, member 8A) – Wnt family member 8A

Wnt8b (wingless-type MMTV integration site family, member 8b) – Wnt family member 8B

Wnt9a (wingless-type MMTV integration site 9A) – Wnt family member 9A

Wnt9b (wingless-related MMTV integration site family, member 9B) – Wnt family member 9B

Wnt10a (wingless-type MMTV integration site family, member 10A) – Wnt family member 10A

Wnt10b (wingless-type MMTV integration site family, member 10B) – Wnt family member 10B
Wnt11 (wingless-type MMTV integration site family, member 11) – Wnt family member 11

Wnt16 (wingless-type MMTV integration site family, member 16) – Wnt family member 16

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.