Pard6b (par-6 family cell polarity regulator beta) - Rat Genome Database

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Gene: Pard6b (par-6 family cell polarity regulator beta) Rattus norvegicus
Analyze
Symbol: Pard6b
Name: par-6 family cell polarity regulator beta
RGD ID: 1308205
Description: Predicted to be involved in several processes, including centrosome cycle; establishment or maintenance of cell polarity; and regulation of cellular localization. Part of protein-containing complex. Orthologous to human PARD6B (par-6 family cell polarity regulator beta); PARTICIPATES IN protein kinase C (PKC) signaling pathway; endocytosis pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC362279; par-6 (partitioning defective 6) homolog beta; par-6 (partitioning defective 6) homolog beta (C. elegans); partitioning defective 6 homolog beta
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,209,429 - 177,230,509 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3177,209,258 - 177,230,510 (+)EnsemblGRCr8
mRatBN7.23156,790,540 - 156,811,620 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3160,585,351 - 160,606,433 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03169,084,429 - 169,105,513 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,826,135 - 166,847,217 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,822,111 - 164,843,395 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)Ensemblrn6Rnor6.0
Rnor_5.03170,968,975 - 170,990,259 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43159,230,673 - 159,251,755 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3155,366,567 - 155,386,818 (+)NCBICelera
RGSC_v3.13159,136,214 - 159,157,286 (+)NCBI
Cytogenetic Map3q42NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
1,2-dimethylhydrazine  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-hydroxypropanoic acid  (ISO)
3-chloropropane-1,2-diol  (EXP)
3-methylcholanthrene  (ISO)
4-hydroxyphenyl retinamide  (ISO)
6-propyl-2-thiouracil  (EXP)
acrolein  (ISO)
acrylamide  (ISO)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
alpha-pinene  (ISO)
amitrole  (EXP)
amphetamine  (EXP)
amphotericin B  (ISO)
aristolochic acid A  (ISO)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
CGP 52608  (ISO)
chlorpyrifos  (ISO)
cobalt dichloride  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) sulfate  (ISO)
Dibutyl phosphate  (ISO)
dibutyl phthalate  (EXP)
diuron  (EXP,ISO)
dorsomorphin  (ISO)
formaldehyde  (ISO)
gentamycin  (EXP)
indole-3-methanol  (EXP)
ivermectin  (ISO)
leflunomide  (ISO)
levonorgestrel  (ISO)
methapyrilene  (EXP)
methimazole  (EXP)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
N-nitrosodiethylamine  (EXP)
ochratoxin A  (ISO)
ozone  (ISO)
paracetamol  (EXP)
pentachlorophenol  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
potassium dichromate  (ISO)
rac-lactic acid  (ISO)
rotenone  (ISO)
SB 431542  (ISO)
silicon dioxide  (ISO)
silver atom  (ISO)
silver(0)  (ISO)
sodium arsenite  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
testosterone undecanoate  (ISO)
thioacetamide  (EXP)
titanium dioxide  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
apical part of cell  (IEA,ISO)
apical plasma membrane  (IBA,IEA,ISO)
bicellular tight junction  (IEA,ISO)
cell cortex  (IBA,IEA,ISO)
cytoplasm  (IEA)
cytosol  (IEA,ISO)
nucleus  (IBA,IEA,ISO)
plasma membrane  (IEA,ISO)
protein-containing complex  (IDA)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
5. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
6. The PAR-aPKC system: lessons in polarity. Suzuki A and Ohno S, J Cell Sci. 2006 Mar 15;119(Pt 6):979-87.
7. Par3/Par6 polarity complex coordinates apical ectoplasmic specialization and blood-testis barrier restructuring during spermatogenesis. Wong EW, etal., Proc Natl Acad Sci U S A. 2008 Jul 15;105(28):9657-62. Epub 2008 Jul 10.
Additional References at PubMed
PMID:12545177   PMID:15950600   PMID:19056867   PMID:19620967   PMID:22333836  


Genomics

Comparative Map Data
Pard6b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83177,209,429 - 177,230,509 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl3177,209,258 - 177,230,510 (+)EnsemblGRCr8
mRatBN7.23156,790,540 - 156,811,620 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx3160,585,351 - 160,606,433 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03169,084,429 - 169,105,513 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03166,826,135 - 166,847,217 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.03164,822,111 - 164,843,395 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)Ensemblrn6Rnor6.0
Rnor_5.03170,968,975 - 170,990,259 (+)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.43159,230,673 - 159,251,755 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera3155,366,567 - 155,386,818 (+)NCBICelera
RGSC_v3.13159,136,214 - 159,157,286 (+)NCBI
Cytogenetic Map3q42NCBI
PARD6B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382050,731,580 - 50,753,741 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2050,731,382 - 50,756,795 (+)Ensemblhg38GRCh38
GRCh372049,348,117 - 49,370,278 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362048,781,488 - 48,803,685 (+)NCBIBuild 36Build 36hg18NCBI36
Build 342048,781,730 - 48,800,432NCBI
Celera2046,052,360 - 46,074,607 (+)NCBICelera
Cytogenetic Map20q13.13NCBI
HuRef2046,096,474 - 46,118,701 (+)NCBIHuRef
CHM1_12049,253,147 - 49,275,696 (+)NCBICHM1_1
T2T-CHM13v2.02052,501,886 - 52,524,081 (+)NCBIT2T-CHM13v2.0
Pard6b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392167,922,924 - 167,943,123 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2167,922,924 - 167,943,123 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm382168,081,004 - 168,101,203 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2168,081,004 - 168,101,203 (+)Ensemblmm10GRCm38
MGSCv372167,906,504 - 167,926,703 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv362167,772,490 - 167,790,415 (+)NCBIMGSCv36mm8
Celera2174,023,444 - 174,043,724 (+)NCBICelera
Cytogenetic Map2H3NCBI
cM Map288.24NCBI
Pard6b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554457,625,303 - 7,638,654 (-)Ensembl
ChiLan1.0NW_0049554457,625,303 - 7,638,652 (-)NCBIChiLan1.0ChiLan1.0
PARD6B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22156,480,187 - 56,502,616 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12056,473,355 - 56,495,732 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02047,076,007 - 47,098,321 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12048,203,994 - 48,223,814 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2048,203,900 - 48,229,376 (+)EnsemblpanPan2panpan1.1
PARD6B
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12437,108,441 - 37,122,118 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2436,349,345 - 36,365,076 (+)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.02437,816,193 - 37,832,591 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2437,816,255 - 37,832,600 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12437,052,429 - 37,068,151 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02437,186,155 - 37,201,876 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02437,730,480 - 37,746,871 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Pard6b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640188,500,105 - 188,519,486 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365143,953,753 - 3,966,312 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365143,953,748 - 3,967,871 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PARD6B
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1752,195,041 - 52,213,843 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.11752,195,360 - 52,211,504 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21758,650,703 - 58,651,538 (+)NCBISscrofa10.2Sscrofa10.2susScr3
Sscrofa10.21758,583,393 - 58,588,704 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PARD6B
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1213,218,514 - 13,239,206 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl213,215,929 - 13,237,421 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605061,648,766 - 61,668,024 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Pard6b
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247904,939,592 - 4,960,531 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247904,939,753 - 4,960,432 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Pard6b
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v15149,906,444 - 149,926,469 (-)NCBIRrattus_CSIRO_v1

miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:479
Count of miRNA genes:257
Interacting mature miRNAs:311
Transcripts:ENSRNOT00000014568
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141555229186555229Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3141555229186555229Rat
1582233Insul10Insulin level QTL 105.40.0015blood insulin amount (VT:0001560)serum insulin level times blood glucose level (CMO:0002040)3133259579178259579Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3166376089177728348Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3141555229186555229Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3151075912189428310Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3141555229186555229Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)3129154923182114333Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3141555229186555229Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3161492708189428310Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3141555229186555229Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)351581665184004958Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3166376089189428310Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3161799270187311134Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3133134628178134628Rat
1582213Insul6Insulin level QTL 63.70.0009blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3166376089189428310Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3152055202189428310Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3142898802187898802Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)379649560177741895Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)3145335553189428310Rat
1582256Insul9Insulin level QTL 94.40.0016blood insulin amount (VT:0001560)absolute change in serum insulin level (CMO:0002038)3155759447189428310Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3139299381184299381Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3141508991177728348Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3137114333182114333Rat
1582248Insul7Insulin level QTL 73.90.0041blood insulin amount (VT:0001560)calculated serum insulin level (CMO:0000359)3155759447189428310Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3151075912189428310Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3151075912189428310Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3141555229186555229Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3144575244189428310Rat

Markers in Region
RH136841  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23156,811,291 - 156,811,423 (+)MAPPERmRatBN7.2
Rnor_6.03164,843,067 - 164,843,198NCBIRnor6.0
Rnor_5.03170,989,931 - 170,990,062UniSTSRnor5.0
RGSC_v3.43159,251,427 - 159,251,558UniSTSRGSC3.4
Celera3155,386,490 - 155,386,621UniSTS
RH 3.4 Map31480.7UniSTS
Cytogenetic Map3q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 66 163 91 90 59 92 59 6 355 191 11 142 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000014568   ⟹   ENSRNOP00000014568
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl3177,209,258 - 177,230,510 (+)Ensembl
mRatBN7.2 Ensembl3156,790,540 - 156,811,622 (+)Ensembl
Rnor_6.0 Ensembl3164,822,111 - 164,843,395 (+)Ensembl
RefSeq Acc Id: NM_001108609   ⟹   NP_001102079
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83177,209,429 - 177,230,509 (+)NCBI
mRatBN7.23156,790,540 - 156,811,620 (+)NCBI
Rnor_6.03164,822,111 - 164,843,395 (+)NCBI
Rnor_5.03170,968,975 - 170,990,259 (+)NCBI
RGSC_v3.43159,230,673 - 159,251,755 (+)RGD
Celera3155,366,567 - 155,386,818 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001102079 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL96380 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000014568
  ENSRNOP00000014568.5
RefSeq Acc Id: NP_001102079   ⟸   NM_001108609
- UniProtKB: D4A2F2 (UniProtKB/TrEMBL),   A6JXM9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000014568   ⟸   ENSRNOT00000014568
Protein Domains
PB1   PDZ

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A2F2-F1-model_v2 AlphaFold D4A2F2 1-372 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692696
Promoter ID:EPDNEW_R3221
Type:single initiation site
Name:Pard6b_1
Description:par-6 family cell polarity regulator beta
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03164,822,172 - 164,822,232EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1308205 AgrOrtholog
BioCyc Gene G2FUF-46711 BioCyc
Ensembl Genes ENSRNOG00000010883 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000014568 ENTREZGENE
  ENSRNOT00000014568.6 UniProtKB/TrEMBL
Gene3D-CATH 2.30.42.10 UniProtKB/TrEMBL
  Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1 UniProtKB/TrEMBL
InterPro OPR_PB1 UniProtKB/TrEMBL
  PAR6_homolog UniProtKB/TrEMBL
  PB1-like UniProtKB/TrEMBL
  PB1_Par6 UniProtKB/TrEMBL
  PDZ/DHR/GLGF UniProtKB/TrEMBL
  PDZ_sf UniProtKB/TrEMBL
KEGG Report rno:362279 UniProtKB/TrEMBL
NCBI Gene 362279 ENTREZGENE
PANTHER PAR-6-RELATED UniProtKB/TrEMBL
  PTHR14102:SF4 UniProtKB/TrEMBL
Pfam PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
PhenoGen Pard6b PhenoGen
PROSITE PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
RatGTEx ENSRNOG00000010883 RatGTEx
SMART PB1 UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
Superfamily-SCOP CAD & PB1 domains UniProtKB/TrEMBL
  PDZ UniProtKB/TrEMBL
UniProt A6JXM9 ENTREZGENE, UniProtKB/TrEMBL
  D4A2F2 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-11-19 Pard6b  par-6 family cell polarity regulator beta  Pard6b  par-6 (partitioning defective 6) homolog beta (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 Pard6b  par-6 (partitioning defective 6) homolog beta (C. elegans)   Pard6b_predicted  par-6 (partitioning defective 6) homolog beta (C. elegans) (predicted)  'predicted' is removed 2292626 APPROVED
2005-01-12 Pard6b_predicted  par-6 (partitioning defective 6) homolog beta (C. elegans) (predicted)      Symbol and Name status set to approved 70820 APPROVED