C2cd2 (C2 calcium-dependent domain containing 2) - Rat Genome Database

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Gene: C2cd2 (C2 calcium-dependent domain containing 2) Rattus norvegicus
Analyze
Symbol: C2cd2
Name: C2 calcium-dependent domain containing 2
RGD ID: 735112
Description: Predicted to be located in membrane. Orthologous to human C2CD2 (C2 calcium dependent domain containing 2); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: C2 domain-containing protein 2; hypothetical protein LOC304055; MGC72630; RGD735112; similar to RIKEN cDNA 5830404H04
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,694,680 - 50,759,096 (-)NCBIGRCr8
mRatBN7.21137,225,321 - 37,289,741 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1137,227,415 - 37,289,739 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1145,928,404 - 45,990,048 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01138,599,791 - 38,661,439 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,759,738 - 37,821,394 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01138,354,746 - 38,420,133 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,357,424 - 38,420,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,867,286 - 41,929,981 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,873,369 - 37,935,054 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,930,958 - 37,992,643 (-)NCBI
Celera1137,112,352 - 37,174,079 (-)NCBICelera
Cytogenetic Map11q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2-hydroxypropanoic acid  (ISO)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (EXP)
6-propyl-2-thiouracil  (EXP)
acetamide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
alpha-pinene  (ISO)
amiodarone  (EXP)
amitrole  (EXP)
amphetamine  (EXP)
benzbromarone  (EXP)
benzo[a]pyrene  (ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
C60 fullerene  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
chlorpyrifos  (ISO)
clofibrate  (EXP,ISO)
coumarin  (ISO)
cyproconazole  (ISO)
cytarabine  (ISO)
dexamethasone  (ISO)
diuron  (EXP)
dorsomorphin  (ISO)
endosulfan  (EXP)
epoxiconazole  (ISO)
flutamide  (EXP)
folpet  (ISO)
FR900359  (ISO)
gentamycin  (EXP)
indometacin  (ISO)
inulin  (ISO)
L-ethionine  (EXP)
levofloxacin  (EXP)
methamphetamine  (EXP)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
N,N-diethyl-m-toluamide  (EXP)
omeprazole  (EXP)
ozone  (ISO)
panobinostat  (ISO)
paracetamol  (EXP,ISO)
pentachlorophenol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (EXP)
permethrin  (EXP)
phenylmercury acetate  (ISO)
picoxystrobin  (ISO)
pirinixic acid  (EXP,ISO)
propiconazole  (ISO)
quercetin  (ISO)
rac-lactic acid  (ISO)
raloxifene  (ISO)
resveratrol  (ISO)
rotenone  (EXP)
SB 431542  (ISO)
silicon dioxide  (ISO)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sulfadimethoxine  (EXP)
tamoxifen  (ISO)
temozolomide  (ISO)
tert-butyl hydroperoxide  (ISO)
tetrachloromethane  (EXP)
thimerosal  (ISO)
thioacetamide  (EXP)
trichostatin A  (ISO)
triclosan  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:16780588  


Genomics

Comparative Map Data
C2cd2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81150,694,680 - 50,759,096 (-)NCBIGRCr8
mRatBN7.21137,225,321 - 37,289,741 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1137,227,415 - 37,289,739 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1145,928,404 - 45,990,048 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01138,599,791 - 38,661,439 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01137,759,738 - 37,821,394 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01138,354,746 - 38,420,133 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1138,357,424 - 38,420,119 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01141,867,286 - 41,929,981 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41137,873,369 - 37,935,054 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11137,930,958 - 37,992,643 (-)NCBI
Celera1137,112,352 - 37,174,079 (-)NCBICelera
Cytogenetic Map11q12NCBI
C2CD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382141,885,112 - 41,954,018 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2141,885,112 - 41,954,018 (-)EnsemblGRCh38hg38GRCh38
GRCh372143,305,221 - 43,374,127 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362142,178,288 - 42,247,068 (-)NCBINCBI36Build 36hg18NCBI36
Build 342142,178,290 - 42,219,847NCBI
Celera2128,452,727 - 28,521,539 (-)NCBICelera
Cytogenetic Map21q22.3NCBI
HuRef2128,723,171 - 28,791,614 (-)NCBIHuRef
CHM1_12142,866,059 - 42,934,842 (-)NCBICHM1_1
T2T-CHM13v2.02140,275,427 - 40,344,241 (-)NCBIT2T-CHM13v2.0
C2cd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391697,656,409 - 97,727,248 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1697,656,409 - 97,763,798 (-)EnsemblGRCm39 Ensembl
GRCm381697,855,209 - 97,925,795 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1697,855,209 - 97,962,598 (-)EnsemblGRCm38mm10GRCm38
MGSCv371698,076,816 - 98,144,243 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361698,013,678 - 98,077,513 (-)NCBIMGSCv36mm8
Celera1698,906,746 - 98,974,176 (-)NCBICelera
Cytogenetic Map16C4NCBI
cM Map1657.7NCBI
C2cd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495540739,618,252 - 39,663,885 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495540739,627,435 - 39,665,156 (+)NCBIChiLan1.0ChiLan1.0
C2CD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22237,955,896 - 38,024,803 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12132,810,088 - 32,879,014 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02128,208,474 - 28,277,366 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12141,532,070 - 41,600,080 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2141,532,070 - 41,600,084 (-)Ensemblpanpan1.1panPan2
C2CD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13136,291,853 - 36,355,472 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3136,274,539 - 36,348,657 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3135,443,826 - 35,500,709 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03135,808,806 - 35,866,037 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3135,811,676 - 35,867,188 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13135,702,724 - 35,759,690 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03135,682,219 - 35,739,124 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03136,176,757 - 36,234,044 (-)NCBIUU_Cfam_GSD_1.0
C2cd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440497135,544,860 - 35,596,401 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365001,871,416 - 1,923,070 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365001,870,419 - 1,922,963 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C2CD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13205,246,716 - 205,313,717 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113205,248,991 - 205,313,868 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213215,572,982 - 215,639,714 (-)NCBISscrofa10.2Sscrofa10.2susScr3
C2CD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1285,769,419 - 85,837,269 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl285,766,996 - 85,837,182 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605413,627,878 - 13,698,203 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
C2cd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462474528,346,570 - 28,389,961 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462474528,346,470 - 28,393,529 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in C2cd2
251 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:376
Count of miRNA genes:230
Interacting mature miRNAs:279
Transcripts:ENSRNOT00000002209
Prediction methods:Microtar, Miranda, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300147Bp187Blood pressure QTL 1873.67arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)11169446234Rat
1558659Tescar1Testicular tumor resistance QTL 13.9testis integrity trait (VT:0010572)percentage of study population developing testis tumors during a period of time (CMO:0001261)11104193166113562Rat
1641927Alcrsp10Alcohol response QTL 10alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)11843667453436674Rat
724517Uae18Urinary albumin excretion QTL 183.7urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)111647204744285911Rat
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
10058952Gmadr6Adrenal mass QTL 62.290.0072adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)112295940367959403Rat
8694376Bw156Body weight QTL 1562.250.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
9590313Scort20Serum corticosterone level QTL 206.510.001blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)112328045668280456Rat
9589032Epfw10Epididymal fat weight QTL 109.290.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)112328045668280456Rat
8694424Bw162Body weight QTL 1623.80.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)112328045668280456Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300130Rf20Renal function QTL 204.44kidney glomerulus integrity trait (VT:0010546)kidney glomerulus diameter (CMO:0001166)112952841860324829Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
2298551Neuinf10Neuroinflammation QTL 103.7nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)113123913478851519Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat

Markers in Region
RH131278  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21137,229,019 - 37,229,200 (+)MAPPERmRatBN7.2
Rnor_6.01138,358,445 - 38,358,625NCBIRnor6.0
Rnor_5.01141,868,308 - 41,868,488UniSTSRnor5.0
RGSC_v3.41137,874,391 - 37,874,571UniSTSRGSC3.4
Celera1137,113,374 - 37,113,554UniSTS
RH 3.4 Map11263.71UniSTS
Cytogenetic Map11q12UniSTS
RH132334  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21137,228,191 - 37,228,379 (+)MAPPERmRatBN7.2
Rnor_6.01138,357,617 - 38,357,804NCBIRnor6.0
Rnor_5.01141,867,480 - 41,867,667UniSTSRnor5.0
RGSC_v3.41137,873,563 - 37,873,750UniSTSRGSC3.4
Celera1137,112,546 - 37,112,733UniSTS
RH 3.4 Map11280.3UniSTS
Cytogenetic Map11q12UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 19 26 17 9 17 8 11 21 28 17 11 8
Low 3 24 31 24 10 24 53 7 24
Below cutoff

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_199391 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768573 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008768578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017598014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088395 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088396 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039088398 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010055959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC062389 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473967 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000011 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000002209   ⟹   ENSRNOP00000002209
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1137,228,000 - 37,289,664 (-)Ensembl
Rnor_6.0 Ensembl1138,357,424 - 38,420,032 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000080681   ⟹   ENSRNOP00000068956
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1137,238,933 - 37,289,664 (-)Ensembl
Rnor_6.0 Ensembl1138,366,204 - 38,420,119 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000093979   ⟹   ENSRNOP00000089092
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1137,227,415 - 37,289,664 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000104065   ⟹   ENSRNOP00000078458
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1137,227,999 - 37,289,739 (-)Ensembl
RefSeq Acc Id: NM_199391   ⟹   NP_955423
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,697,357 - 50,759,016 (-)NCBI
mRatBN7.21137,227,998 - 37,289,652 (-)NCBI
Rnor_6.01138,357,423 - 38,420,032 (-)NCBI
Rnor_5.01141,867,286 - 41,929,981 (-)NCBI
RGSC_v3.41137,873,369 - 37,935,054 (-)RGD
Celera1137,112,352 - 37,174,079 (-)RGD
Sequence:
RefSeq Acc Id: XM_008768572   ⟹   XP_008766794
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,759,096 (-)NCBI
mRatBN7.21137,225,321 - 37,289,741 (-)NCBI
Rnor_6.01138,354,746 - 38,420,133 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768573   ⟹   XP_008766795
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,759,096 (-)NCBI
mRatBN7.21137,225,321 - 37,289,741 (-)NCBI
Rnor_6.01138,354,746 - 38,420,133 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768576   ⟹   XP_008766798
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,758,648 (-)NCBI
mRatBN7.21137,225,321 - 37,289,278 (-)NCBI
Rnor_6.01138,354,746 - 38,419,615 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768577   ⟹   XP_008766799
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,758,652 (-)NCBI
mRatBN7.21137,225,321 - 37,289,288 (-)NCBI
Rnor_6.01138,354,746 - 38,419,608 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008768578   ⟹   XP_008766800
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,758,469 (-)NCBI
mRatBN7.21137,225,321 - 37,289,103 (-)NCBI
Rnor_6.01138,354,746 - 38,419,531 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598013   ⟹   XP_017453502
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,759,096 (-)NCBI
mRatBN7.21137,229,496 - 37,289,741 (-)NCBI
Rnor_6.01138,358,966 - 38,420,133 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017598014   ⟹   XP_017453503
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,754,415 (-)NCBI
mRatBN7.21137,225,321 - 37,285,042 (-)NCBI
Rnor_6.01138,354,746 - 38,419,083 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039088395   ⟹   XP_038944323
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,699,030 - 50,759,096 (-)NCBI
mRatBN7.21137,229,672 - 37,289,741 (-)NCBI
RefSeq Acc Id: XM_039088396   ⟹   XP_038944324
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,759,079 (-)NCBI
mRatBN7.21137,225,321 - 37,289,741 (-)NCBI
RefSeq Acc Id: XM_039088398   ⟹   XP_038944326
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,694,680 - 50,728,754 (-)NCBI
mRatBN7.21137,225,321 - 37,261,540 (-)NCBI
RefSeq Acc Id: XR_010055959
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81150,716,090 - 50,759,096 (-)NCBI
Reference Protein Sequences
RefSeq Acc Id: NP_955423   ⟸   NM_199391
- UniProtKB: Q6P691 (UniProtKB/TrEMBL),   A6IQH6 (UniProtKB/TrEMBL),   A0A8I5ZML0 (UniProtKB/TrEMBL),   F7F9E0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766795   ⟸   XM_008768573
- Peptide Label: isoform X2
- UniProtKB: A0A8I5ZML0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766794   ⟸   XM_008768572
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZML0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766798   ⟸   XM_008768576
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZML0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766799   ⟸   XM_008768577
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZML0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008766800   ⟸   XM_008768578
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZML0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453503   ⟸   XM_017598014
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZML0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453502   ⟸   XM_017598013
- Peptide Label: isoform X5
- UniProtKB: A0A0G2JU40 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000068956   ⟸   ENSRNOT00000080681
RefSeq Acc Id: ENSRNOP00000002209   ⟸   ENSRNOT00000002209
RefSeq Acc Id: XP_038944324   ⟸   XM_039088396
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZML0 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038944326   ⟸   XM_039088398
- Peptide Label: isoform X8
RefSeq Acc Id: XP_038944323   ⟸   XM_039088395
- Peptide Label: isoform X3
- UniProtKB: A0A0G2JU40 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSRNOP00000089092   ⟸   ENSRNOT00000093979
RefSeq Acc Id: ENSRNOP00000078458   ⟸   ENSRNOT00000104065
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6P691-F1-model_v2 AlphaFold Q6P691 1-696 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698096
Promoter ID:EPDNEW_R8621
Type:multiple initiation site
Name:C2cd2_1
Description:C2 calcium-dependent domain containing 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01138,420,087 - 38,420,147EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:735112 AgrOrtholog
BioCyc Gene G2FUF-21670 BioCyc
Ensembl Genes ENSRNOG00000001621 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000002209 ENTREZGENE
  ENSRNOT00000002209.6 UniProtKB/TrEMBL
  ENSRNOT00000080681.2 UniProtKB/TrEMBL
  ENSRNOT00000093979.1 UniProtKB/TrEMBL
  ENSRNOT00000104065.1 UniProtKB/TrEMBL
Gene3D-CATH 2.60.40.150 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:5620907 IMAGE-MGC_LOAD
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  C2CD2/C2CD2L UniProtKB/TrEMBL
  SMP_C2CD2L UniProtKB/TrEMBL
KEGG Report rno:304055 UniProtKB/TrEMBL
MGC_CLONE MGC:72630 IMAGE-MGC_LOAD
NCBI Gene 304055 ENTREZGENE
PANTHER C2 DOMAIN-CONTAINING PROTEIN 2 UniProtKB/TrEMBL
  PTHR21119 UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  SMP_C2CD2L UniProtKB/TrEMBL
PhenoGen C2cd2 PhenoGen
PROSITE PS50004 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000001621 RatGTEx
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A0G2JU40 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZML0 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A9G0_RAT UniProtKB/TrEMBL
  A6IQH6 ENTREZGENE, UniProtKB/TrEMBL
  A6IQH8_RAT UniProtKB/TrEMBL
  F7F9E0 ENTREZGENE, UniProtKB/TrEMBL
  Q6P691 ENTREZGENE
UniProt Secondary Q6P691 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-07 C2cd2  C2 calcium-dependent domain containing 2  RGD735112  similar to RIKEN cDNA 5830404H04  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 RGD735112  similar to RIKEN cDNA 5830404H04      Symbol updated 1299863 APPROVED
2005-09-30 MGC72630        Symbol and Name status set to provisional 70820 PROVISIONAL