Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tor1aip2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:22206623 | Tor1aip2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of IFRG15 mRNA | CTD | PMID:17942748 | Tor1aip2 | Rat | 17beta-estradiol | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Estradiol results in increased expression of TOR1AIP2 mRNA | CTD | PMID:23019147 | Tor1aip2 | Rat | 2,2',4,4'-Tetrabromodiphenyl ether | decreases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:19095052 | Tor1aip2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of IFRG15 mRNA | CTD | PMID:21570461 | Tor1aip2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:33387578 and PMID:34747641 | Tor1aip2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TOR1AIP2 mRNA | CTD | PMID:34747641 | Tor1aip2 | Rat | acrolein | multiple interactions | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of TOR1AIP2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:32699268 | Tor1aip2 | Rat | acrylamide | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of TOR1AIP2 mRNA | CTD | PMID:32763439 | Tor1aip2 | Rat | aflatoxin B1 | increases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Aflatoxin B1 results in increased expression of TOR1AIP2 mRNA | CTD | PMID:19770486 | Tor1aip2 | Rat | aflatoxin B1 | decreases methylation | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TOR1AIP2 gene | CTD | PMID:27153756 | Tor1aip2 | Rat | aflatoxin B1 | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of TOR1AIP2 mRNA | CTD | PMID:21641981 | Tor1aip2 | Rat | alpha-pinene | multiple interactions | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of TOR1AIP2 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:32699268 | Tor1aip2 | Rat | arsenous acid | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of IFRG15 mRNA | CTD | PMID:20458559 | Tor1aip2 | Rat | benzo[a]pyrene | increases mutagenesis | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased mutagenesis of TOR1AIP2 gene | CTD | PMID:25435355 | Tor1aip2 | Rat | benzo[a]pyrene | increases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of TOR1AIP2 mRNA | CTD | PMID:22228805 | Tor1aip2 | Rat | benzo[a]pyrene diol epoxide I | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | 7 more ... | CTD | PMID:26238291 | Tor1aip2 | Rat | Benzo[ghi]perylene | increases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | 1 and 12-benzoperylene results in increased expression of TOR1AIP2 mRNA | CTD | PMID:26377693 | Tor1aip2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:25181051 | Tor1aip2 | Rat | bisphenol A | decreases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of TOR1AIP2 protein | CTD | PMID:34186270 | Tor1aip2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TOR1AIP2 mRNA | CTD | PMID:30816183 and PMID:32528016 | Tor1aip2 | Rat | butanal | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of TOR1AIP2 mRNA | CTD | PMID:26079696 | Tor1aip2 | Rat | caffeine | decreases phosphorylation | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of TOR1AIP2 protein | CTD | PMID:35688186 | Tor1aip2 | Rat | calcitriol | multiple interactions | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of TOR1AIP2 mRNA | CTD | PMID:21592394 | Tor1aip2 | Rat | calcitriol | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Calcitriol results in increased expression of TOR1AIP2 mRNA | CTD | PMID:21592394 | Tor1aip2 | Rat | carbon nanotube | decreases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25620056 | Tor1aip2 | Rat | carbon nanotube | increases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 | Tor1aip2 | Rat | casticin | decreases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | casticin results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:28444820 | Tor1aip2 | Rat | CGP 52608 | multiple interactions | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to IFRG15 gene] and CGP 52608 promotes the reaction [RORA protein binds to TOR1AIP2 gene] | CTD | PMID:28238834 | Tor1aip2 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of TOR1AIP2 mRNA | CTD | PMID:24386269 | Tor1aip2 | Rat | copper(II) sulfate | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of IFRG15 mRNA and Copper Sulfate results in increased expression of TOR1AIP2 mRNA | CTD | PMID:19549813 | Tor1aip2 | Rat | coumarin | affects phosphorylation | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | coumarin affects the phosphorylation of TOR1AIP2 protein | CTD | PMID:35688186 | Tor1aip2 | Rat | diarsenic trioxide | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Arsenic Trioxide results in increased expression of IFRG15 mRNA | CTD | PMID:20458559 | Tor1aip2 | Rat | dibutyl phthalate | increases expression | EXP | | 6480464 | Dibutyl Phthalate results in increased expression of TOR1AIP2 mRNA | CTD | PMID:21266533 | Tor1aip2 | Rat | dioxygen | decreases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Oxygen deficiency results in decreased expression of IFRG15 mRNA | CTD | PMID:24236059 | Tor1aip2 | Rat | folic acid | decreases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Folic Acid results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:25629700 | Tor1aip2 | Rat | formaldehyde | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of IFRG15 mRNA | CTD | PMID:20655997 | Tor1aip2 | Rat | FR900359 | decreases phosphorylation | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of TOR1AIP2 protein | CTD | PMID:37730182 | Tor1aip2 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of TOR1AIP2 mRNA | CTD | PMID:33387578 | Tor1aip2 | Rat | hexadecanoic acid | increases phosphorylation | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Palmitic Acid results in increased phosphorylation of TOR1AIP2 protein | CTD | PMID:28073184 | Tor1aip2 | Rat | hydrazine | increases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | hydrazine results in increased expression of IFRG15 mRNA | CTD | PMID:15282401 | Tor1aip2 | Rat | hydrogen peroxide | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Hydrogen Peroxide results in increased expression of TOR1AIP2 mRNA | CTD | PMID:18951874 | Tor1aip2 | Rat | lipopolysaccharide | affects expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Lipopolysaccharides affects the expression of TOR1AIP2 mRNA | CTD | PMID:24056979 | Tor1aip2 | Rat | lipopolysaccharide | multiple interactions | ISO | Tor1aip2 (Mus musculus) | 6480464 | methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of TOR1AIP2 mRNA] | CTD | PMID:24056979 | Tor1aip2 | Rat | metam | multiple interactions | ISO | Tor1aip2 (Mus musculus) | 6480464 | methyldithiocarbamate inhibits the reaction [Lipopolysaccharides affects the expression of TOR1AIP2 mRNA] | CTD | PMID:24056979 | Tor1aip2 | Rat | methapyrilene | decreases expression | EXP | | 6480464 | Methapyrilene results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:30467583 | Tor1aip2 | Rat | methylmercury chloride | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | methylmercuric chloride results in increased expression of TOR1AIP2 mRNA | CTD | PMID:28001369 | Tor1aip2 | Rat | nickel atom | decreases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Nickel results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:23195993 | Tor1aip2 | Rat | ozone | decreases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Ozone results in decreased expression of IFRG15 mRNA | CTD | PMID:16183385 | Tor1aip2 | Rat | ozone | multiple interactions | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in decreased expression of TOR1AIP2 mRNA more ... | CTD | PMID:32699268 | Tor1aip2 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of TOR1AIP2 mRNA | CTD | PMID:33387578 | Tor1aip2 | Rat | pentachlorophenol | affects expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | Pentachlorophenol affects the expression of TOR1AIP2 mRNA | CTD | PMID:23892564 | Tor1aip2 | Rat | PhIP | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in increased expression of TOR1AIP2 mRNA | CTD | PMID:20816883 | Tor1aip2 | Rat | pirinixic acid | decreases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:18445702 | Tor1aip2 | Rat | resveratrol | multiple interactions | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of TOR1AIP2 mRNA | CTD | PMID:23557933 | Tor1aip2 | Rat | sodium arsenite | decreases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:28595984 | Tor1aip2 | Rat | Soman | increases expression | EXP | | 6480464 | Soman results in increased expression of TOR1AIP2 mRNA | CTD | PMID:19281266 | Tor1aip2 | Rat | testosterone | multiple interactions | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in increased expression of TOR1AIP2 mRNA | CTD | PMID:21592394 | Tor1aip2 | Rat | testosterone | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Testosterone results in increased expression of TOR1AIP2 mRNA | CTD | PMID:21592394 | Tor1aip2 | Rat | thioacetamide | decreases expression | EXP | | 6480464 | Thioacetamide results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:34492290 | Tor1aip2 | Rat | thiram | decreases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Thiram results in decreased expression of TOR1AIP2 mRNA | CTD | PMID:38568856 | Tor1aip2 | Rat | titanium dioxide | decreases methylation | ISO | Tor1aip2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of TOR1AIP2 gene | CTD | PMID:35295148 | Tor1aip2 | Rat | trichostatin A | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of TOR1AIP2 mRNA | CTD | PMID:24935251 | Tor1aip2 | Rat | trichostatin A | affects expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | trichostatin A affects the expression of TOR1AIP2 mRNA | CTD | PMID:28542535 | Tor1aip2 | Rat | triphenyl phosphate | affects expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TOR1AIP2 mRNA | CTD | PMID:37042841 | Tor1aip2 | Rat | triptonide | affects expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | triptonide affects the expression of TOR1AIP2 mRNA | CTD | PMID:33045310 | Tor1aip2 | Rat | trovafloxacin | increases expression | ISO | Tor1aip2 (Mus musculus) | 6480464 | trovafloxacin results in increased expression of TOR1AIP2 mRNA | CTD | PMID:35537566 | Tor1aip2 | Rat | urethane | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Urethane results in increased expression of TOR1AIP2 mRNA | CTD | PMID:28818685 | Tor1aip2 | Rat | valproic acid | increases expression | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TOR1AIP2 mRNA | CTD | PMID:24935251 | Tor1aip2 | Rat | valproic acid | decreases methylation | ISO | TOR1AIP2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of TOR1AIP2 gene | CTD | PMID:29154799 | |