Tmem255a (transmembrane protein 255A) - Rat Genome Database

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Gene: Tmem255a (transmembrane protein 255A) Rattus norvegicus
Analyze
Symbol: Tmem255a
Name: transmembrane protein 255A
RGD ID: 727788
Description: Predicted to act upstream of or within response to bacterium. Predicted to be located in membrane. Orthologous to human TMEM255A (transmembrane protein 255A); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; atrazine; bisphenol A.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Fam70a; family with sequence similarity 70, member A; hypothetical protein LOC313453; LOC102546820; LOC313453; RGD727788; uncharacterized LOC102546820
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X121,836,443 - 121,900,718 (-)NCBIGRCr8
mRatBN7.2X116,970,793 - 117,035,008 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX116,970,695 - 117,035,008 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX119,070,181 - 119,133,290 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X122,639,330 - 122,702,426 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X120,185,208 - 120,248,288 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X124,400,686 - 124,465,156 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX124,328,735 - 124,465,110 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X124,486,033 - 124,550,923 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X7,098,688 - 7,161,741 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X7,104,243 - 7,167,297 (+)NCBI
CeleraX116,188,387 - 116,245,740 (-)NCBICelera
Cytogenetic MapXq35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
membrane  (IEA)

References

References - curated
# Reference Title Reference Citation
1. NCBI rat LocusLink and RefSeq merged data October 15, 2003 NCBI rat LocusLink and RefSeq merged data October 15, 2003
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:23012479  


Genomics

Comparative Map Data
Tmem255a
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X121,836,443 - 121,900,718 (-)NCBIGRCr8
mRatBN7.2X116,970,793 - 117,035,008 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX116,970,695 - 117,035,008 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_UtxX119,070,181 - 119,133,290 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X122,639,330 - 122,702,426 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X120,185,208 - 120,248,288 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X124,400,686 - 124,465,156 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX124,328,735 - 124,465,110 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0X124,486,033 - 124,550,923 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4X7,098,688 - 7,161,741 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1X7,104,243 - 7,167,297 (+)NCBI
CeleraX116,188,387 - 116,245,740 (-)NCBICelera
Cytogenetic MapXq35NCBI
TMEM255A
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X120,251,433 - 120,311,461 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX120,258,650 - 120,311,556 (-)EnsemblGRCh38hg38GRCh38
GRCh37X119,392,505 - 119,445,316 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X119,276,533 - 119,329,419 (-)NCBINCBI36Build 36hg18NCBI36
CeleraX119,858,090 - 119,910,982 (-)NCBICelera
Cytogenetic MapXq24NCBI
HuRefX108,844,953 - 108,897,433 (-)NCBIHuRef
CHM1_1X119,303,796 - 119,356,597 (-)NCBICHM1_1
T2T-CHM13v2.0X118,626,490 - 118,686,494 (-)NCBIT2T-CHM13v2.0
Tmem255a
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X37,285,450 - 37,341,373 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX37,285,450 - 37,341,316 (-)EnsemblGRCm39 Ensembl
GRCm38X38,196,573 - 38,252,496 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX38,196,573 - 38,252,439 (-)EnsemblGRCm38mm10GRCm38
MGSCv37X35,550,478 - 35,605,658 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36X34,441,933 - 34,497,024 (-)NCBIMGSCv36mm8
CeleraX25,842,880 - 25,898,015 (-)NCBICelera
Cytogenetic MapXA3.3NCBI
cM MapX22.46NCBI
Tmem255a
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555721,574,739 - 1,628,124 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555721,574,785 - 1,628,770 (+)NCBIChiLan1.0ChiLan1.0
TMEM255A
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X119,805,876 - 119,858,497 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X119,809,481 - 119,862,101 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X109,530,719 - 109,583,320 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X119,718,047 - 119,770,580 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX119,718,047 - 119,770,580 (-)Ensemblpanpan1.1panPan2
TMEM255A
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X92,251,820 - 92,301,660 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX92,251,816 - 92,301,558 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaX78,280,937 - 78,333,039 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0X93,989,942 - 94,041,992 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX93,989,944 - 94,041,993 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X91,444,928 - 91,497,015 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X93,201,798 - 93,253,853 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X92,982,830 - 93,034,915 (-)NCBIUU_Cfam_GSD_1.0
Tmem255a
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X91,206,027 - 91,265,888 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364799,721,633 - 9,781,509 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049364799,721,602 - 9,781,468 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TMEM255A
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX98,413,949 - 98,464,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1X98,412,286 - 98,464,683 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X113,038,431 - 113,089,119 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TMEM255A
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Vero_WHO_p1.0NW_02366606532,981,264 - 33,033,287 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Tmem255a
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462493169,514 - 148,512 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462493169,622 - 148,455 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Tmem255a
149 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:121
Count of miRNA genes:110
Interacting mature miRNAs:115
Transcripts:ENSRNOT00000036472
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1598856Memor1Memory QTL 11.9exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)X103312877148312877Rat
1598872Memor14Memory QTL 144.5exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X93956491138956491Rat
1598809Memor15Memory QTL 154.4exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X103312877148312877Rat
738025Stresp3Stress response QTL 34.610.0066stress-related behavior trait (VT:0010451)defensive burying - approachX100567703150256146Rat
61430Cia18Collagen induced arthritis QTL 183.1joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X14843113120568734Rat
738029Stresp2Stress response QTL 23.40.0004stress-related behavior trait (VT:0010451)defensive burying - approachX112934952138400867Rat
61431Cia19Collagen induced arthritis QTL 194.4joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)X65612192120568734Rat
5685004Bss104Bone structure and strength QTL 1043.9tibia area (VT:1000281)tibia area measurement (CMO:0001382)X113805422126975220Rat
10059603Bw174Body weight QTL 1743.40.025body mass (VT:0001259)body weight (CMO:0000012)X113937816152453651Rat
724551Glom1Glomerulus QTL 12.80.0004kidney glomerulus morphology trait (VT:0005325)count of superficial glomeruli not directly contacting the kidney surface (CMO:0001002)X75294106120294106Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between time of physical contact/close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X41052407146860749Rat

Markers in Region
DXRat99  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X117,002,093 - 117,002,232 (+)MAPPERmRatBN7.2
Rnor_6.0X124,432,236 - 124,432,374NCBIRnor6.0
Rnor_5.0X124,518,001 - 124,518,139UniSTSRnor5.0
RGSC_v3.4X7,131,417 - 7,131,556RGDRGSC3.4
RGSC_v3.4X7,131,418 - 7,131,556UniSTSRGSC3.4
RGSC_v3.1X7,136,973 - 7,137,112RGD
CeleraX116,219,693 - 116,219,837UniSTS
SHRSP x BN MapX34.2399RGD
SHRSP x BN MapX34.2399UniSTS
Cytogenetic MapXq11UniSTS
RH131768  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X116,970,298 - 116,970,480 (+)MAPPERmRatBN7.2
Rnor_6.0X124,326,258 - 124,326,439NCBIRnor6.0
Rnor_6.0X124,400,192 - 124,400,373NCBIRnor6.0
Rnor_5.0X124,485,957 - 124,486,138UniSTSRnor5.0
Rnor_5.0X124,412,023 - 124,412,204UniSTSRnor5.0
RGSC_v3.4X7,163,764 - 7,163,945UniSTSRGSC3.4
CeleraX116,187,893 - 116,188,074UniSTS
Cytogenetic MapXq11UniSTS
AW260253  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X116,970,302 - 116,970,429 (+)MAPPERmRatBN7.2
Rnor_6.0X124,400,196 - 124,400,322NCBIRnor6.0
Rnor_6.0X124,326,262 - 124,326,388NCBIRnor6.0
Rnor_5.0X124,412,027 - 124,412,153UniSTSRnor5.0
Rnor_5.0X124,485,961 - 124,486,087UniSTSRnor5.0
RGSC_v3.4X7,163,815 - 7,163,941UniSTSRGSC3.4
CeleraX116,187,897 - 116,188,023UniSTS
Cytogenetic MapXq11UniSTS
UniSTS:238015  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X116,970,304 - 116,970,426 (+)MAPPERmRatBN7.2
Rnor_6.0X124,400,198 - 124,400,319NCBIRnor6.0
Rnor_6.0X124,326,264 - 124,326,385NCBIRnor6.0
Rnor_5.0X124,412,029 - 124,412,150UniSTSRnor5.0
Rnor_5.0X124,485,963 - 124,486,084UniSTSRnor5.0
RGSC_v3.4X7,163,818 - 7,163,939UniSTSRGSC3.4
CeleraX116,187,899 - 116,188,020UniSTS
Cytogenetic MapXq11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 10 49 113 80 79 48 25 48 6 201 96 93 40 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000036472   ⟹   ENSRNOP00000032797
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX116,971,941 - 117,035,008 (-)Ensembl
Rnor_6.0 EnsemblX124,402,868 - 124,464,963 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000077697   ⟹   ENSRNOP00000070429
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX116,970,695 - 117,035,008 (-)Ensembl
Rnor_6.0 EnsemblX124,328,735 - 124,465,110 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000104047   ⟹   ENSRNOP00000089978
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX116,971,941 - 117,035,008 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000109556   ⟹   ENSRNOP00000084474
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX116,971,941 - 117,035,008 (-)Ensembl
RefSeq Acc Id: NM_182822   ⟹   NP_877974
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X121,837,587 - 121,900,649 (-)NCBI
mRatBN7.2X116,971,941 - 117,035,008 (-)NCBI
Rnor_6.0X124,401,834 - 124,465,154 (-)NCBI
Rnor_5.0X124,486,033 - 124,550,923 (-)NCBI
RGSC_v3.4X7,098,688 - 7,161,741 (+)RGD
Sequence:
RefSeq Acc Id: XM_006257479   ⟹   XP_006257541
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X121,836,443 - 121,900,718 (-)NCBI
mRatBN7.2X116,970,793 - 117,035,008 (-)NCBI
Rnor_6.0X124,400,686 - 124,465,156 (-)NCBI
Rnor_5.0X124,486,033 - 124,550,923 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039099704   ⟹   XP_038955632
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X121,836,443 - 121,900,629 (-)NCBI
mRatBN7.2X116,970,793 - 117,035,008 (-)NCBI
RefSeq Acc Id: NP_877974   ⟸   NM_182822
- UniProtKB: Q7TMP6 (UniProtKB/Swiss-Prot),   F1LQE2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006257541   ⟸   XM_006257479
- Peptide Label: isoform X1
- UniProtKB: Q7TMP6 (UniProtKB/Swiss-Prot),   A0A8I6A1D4 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000032797   ⟸   ENSRNOT00000036472
Ensembl Acc Id: ENSRNOP00000070429   ⟸   ENSRNOT00000077697
RefSeq Acc Id: XP_038955632   ⟸   XM_039099704
- Peptide Label: isoform X2
- UniProtKB: A0A8I6A8E3 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000084474   ⟸   ENSRNOT00000109556
Ensembl Acc Id: ENSRNOP00000089978   ⟸   ENSRNOT00000104047

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q7TMP6-F1-model_v2 AlphaFold Q7TMP6 1-351 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701996
Promoter ID:EPDNEW_R12518
Type:initiation region
Name:Tmem255a_1
Description:transmembrane protein 255A
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X124,465,091 - 124,465,151EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:727788 AgrOrtholog
BioCyc Gene G2FUF-1261 BioCyc
Ensembl Genes ENSRNOG00000028085 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000036472.7 UniProtKB/TrEMBL
  ENSRNOT00000077697.2 UniProtKB/TrEMBL
  ENSRNOT00000104047.1 UniProtKB/TrEMBL
  ENSRNOT00000109556.1 UniProtKB/TrEMBL
InterPro TMEM255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:313453 UniProtKB/TrEMBL
NCBI Gene 313453 ENTREZGENE
PANTHER PTHR33721 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRANSMEMBRANE PROTEIN 255A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FAM70 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tmem255a PhenoGen
RatGTEx ENSRNOG00000028085 RatGTEx
UniProt A0A0G2JXW6_RAT UniProtKB/TrEMBL
  A0A8I6A1D4 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6A8E3 ENTREZGENE, UniProtKB/TrEMBL
  F1LQE2 ENTREZGENE, UniProtKB/TrEMBL
  Q7TMP6 ENTREZGENE, UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Tmem255a  transmembrane protein 255A  LOC102546820  uncharacterized LOC102546820  Data merged from RGD:7604956 737654 PROVISIONAL
2013-12-18 LOC102546820  uncharacterized LOC102546820      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-12-10 Tmem255a  transmembrane protein 255A  Fam70a  family with sequence similarity 70, member A  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Fam70a  family with sequence similarity 70, member A  RGD727788  hypothetical protein LOC313453  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 RGD727788  hypothetical protein LOC313453  LOC313453    Symbol updated 1299863 APPROVED
2005-10-12 LOC313453        Symbol and Name status set to provisional 70820 PROVISIONAL