Cdk11b (cyclin-dependent kinase 11B) - Rat Genome Database

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Gene: Cdk11b (cyclin-dependent kinase 11B) Rattus norvegicus
Analyze
Symbol: Cdk11b
Name: cyclin-dependent kinase 11B
RGD ID: 628604
Description: Predicted to enable ATP binding activity and protein serine/threonine kinase activity. Predicted to be involved in several processes, including protein phosphorylation; regulation of cell growth; and regulation of mRNA processing. Predicted to act upstream of or within blastocyst development; negative regulation of apoptotic signaling pathway; and regulation of mitotic nuclear division. Predicted to be located in nuclear membrane and perinuclear region of cytoplasm. Predicted to be active in nucleus. Orthologous to human CDK11A (cyclin dependent kinase 11A) and CDK11B (cyclin dependent kinase 11B); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 4,4'-sulfonyldiphenol; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: Cdc2l1; Cdk11; cell division cycle 2 homolog (S.pombe)-like 1; cell division cycle 2 homolog-like 1; cell division cycle 2-like protein kinase 1; cell division protein kinase 11; cyclin-dependent kinase 11; galactosyltransferase-associated protein kinase p58/GTA; PITSLRE serine/threonine-protein kinase CDC2L1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,495,042 - 171,521,143 (+)NCBIGRCr8
mRatBN7.25166,212,761 - 166,238,883 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,212,829 - 166,238,876 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5168,917,908 - 168,943,888 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,739,324 - 170,765,307 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,701,863 - 170,727,846 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,051,900 - 173,078,049 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,052,063 - 173,078,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,527,409 - 176,553,763 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,459,111 - 172,486,012 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5164,414,228 - 164,439,806 (+)NCBICelera
Cytogenetic Map5q36NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Characterization of the synthesis and expression of the GTA-kinase from transformed and normal rodent cells. Kerr M, etal., Biochim Biophys Acta 1994 Aug 2;1218(3):375-87.
3. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
4. Protein expression pattern of CDK11(p58) during testicular development in the mouse. Niu Z, etal., Mol Cell Biochem 2005 Feb;270(1-2):99-106.
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8195233   PMID:8889548   PMID:10882096   PMID:12501247   PMID:15060143   PMID:22527143   PMID:22681889   PMID:23703121  


Genomics

Comparative Map Data
Cdk11b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,495,042 - 171,521,143 (+)NCBIGRCr8
mRatBN7.25166,212,761 - 166,238,883 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,212,829 - 166,238,876 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5168,917,908 - 168,943,888 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,739,324 - 170,765,307 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,701,863 - 170,727,846 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,051,900 - 173,078,049 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,052,063 - 173,078,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,527,409 - 176,553,763 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,459,111 - 172,486,012 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5164,414,228 - 164,439,806 (+)NCBICelera
Cytogenetic Map5q36NCBI
CDK11B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,635,225 - 1,659,004 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,635,225 - 1,659,012 (-)EnsemblGRCh38hg38GRCh38
GRCh3711,570,603 - 1,590,465 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,624,180 - 1,645,637 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map1p36.33NCBI
HuRef1839,060 - 867,349 (-)NCBIHuRef
CHM1_111,558,156 - 1,577,529 (-)NCBICHM1_1
T2T-CHM13v2.011,069,728 - 1,093,685 (-)NCBIT2T-CHM13v2.0
Cdk11b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,709,303 - 155,734,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,709,311 - 155,734,395 (+)EnsemblGRCm39 Ensembl
GRCm384155,624,841 - 155,649,935 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,624,854 - 155,649,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv374154,998,978 - 155,024,041 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364154,468,669 - 154,493,732 (+)NCBIMGSCv36mm8
Celera4157,899,879 - 157,924,805 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.73NCBI
Cdk11b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554869,251,242 - 9,270,218 (+)NCBIChiLan1.0ChiLan1.0
CDK11B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,558,305 - 226,581,539 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,214,256 - 225,237,485 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01399,997 - 423,094 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,557,887 - 1,567,942 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,558,423 - 1,579,305 (-)Ensemblpanpan1.1panPan2
CDK11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,698,267 - 56,714,075 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,773,892 - 56,789,740 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,900,241 - 56,916,116 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,900,247 - 56,916,079 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,891,042 - 56,906,886 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,783,340 - 56,799,187 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0557,173,307 - 57,189,184 (-)NCBIUU_Cfam_GSD_1.0
CDK11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1663,804,914 - 63,819,960 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,234,564 - 58,249,513 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103225783
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120129,848,297 - 129,873,287 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605434,303,072 - 34,328,300 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Cdk11b
64 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:154
Count of miRNA genes:116
Interacting mature miRNAs:131
Transcripts:ENSRNOT00000050188
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10053720Scort26Serum corticosterone level QTL 262.060.0147blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)5124965598166875058Rat
631272Lanf1Left ventricular atrial natriuretic factor QTL 112heart left ventricle natriuretic peptide A amount (VT:0010596)heart left ventricle natriuretic peptide A level (CMO:0002165)5151113452166875058Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
631562Apr2Acute phase response QTL 23.7blood murinoglobulin 1 amount (VT:0010597)plasma murinoglobulin 1 level (CMO:0001931)5135927956166875058Rat
634349Bp139Blood pressure QTL 1390.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5128924607166875058Rat
61444Strs2Sensitivity to stroke QTL 24.7cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)5135929696166875058Rat
724525Bp147Blood pressure QTL 1474.30.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5126424772166875058Rat
1549904Neuinf1Neuroinflammation QTL 130nervous system integrity trait (VT:0010566)blood T lymphocyte count (CMO:0000110)5154828214166875058Rat
738018Anxrr4Anxiety related response QTL 45.1exploratory behavior trait (VT:0010471)percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)5130130159166875058Rat
8552908Pigfal4Plasma insulin-like growth factor 1 level QTL 46.6blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)5128506074166875058Rat
7794791Mcs33Mammary carcinoma susceptibility QTL 331.93mammary gland integrity trait (VT:0010552)mammary tumor incidence/prevalence measurement (CMO:0000946)5131345754166875058Rat
1302790Scl20Serum cholesterol level QTL 206.40.0001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)582394392166664054Rat
1598861Cm64Cardiac mass QTL 642.9heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)5127798274166875058Rat
1641920Colcs1Colorectal carcinoma susceptibility QTL 12.990.0055intestine integrity trait (VT:0010554)benign colorectal tumor surface area measurement (CMO:0001799)5121846814166846814Rat
1598819Bp292Blood pressure QTL 2924.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)5127798274166875058Rat
8694169Bw148Body weight QTL 14850.001body mass (VT:0001259)body weight gain (CMO:0000420)5128506074166875058Rat
1331721Bp210Blood pressure QTL 2103.413arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)5143069996166846814Rat

Markers in Region
RH131250  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,210,707 - 166,210,901 (+)MAPPERmRatBN7.2
Rnor_6.05173,049,881 - 173,050,074NCBIRnor6.0
Rnor_5.05176,525,368 - 176,525,561UniSTSRnor5.0
RGSC_v3.45172,457,564 - 172,457,757UniSTSRGSC3.4
Celera5164,412,045 - 164,412,238UniSTS
RH 3.4 Map51143.8UniSTS
Cytogenetic Map5q36UniSTS
RH134324  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,238,039 - 166,238,442 (+)MAPPERmRatBN7.2
mRatBN7.2X107,589,713 - 107,589,896 (+)MAPPERmRatBN7.2
Rnor_6.0X115,270,488 - 115,270,670NCBIRnor6.0
Rnor_6.05173,077,208 - 173,077,610NCBIRnor6.0
Rnor_5.05176,552,922 - 176,553,324UniSTSRnor5.0
Rnor_5.0X113,722,731 - 113,722,913UniSTSRnor5.0
RGSC_v3.45172,485,313 - 172,485,715UniSTSRGSC3.4
RGSC_v3.4X34,505,206 - 34,505,388UniSTSRGSC3.4
CeleraX106,987,457 - 106,987,639UniSTS
Celera5164,438,965 - 164,439,367UniSTS
RH 3.4 Map51145.9UniSTS
Cytogenetic Map5q36UniSTS
Cytogenetic MapXq14UniSTS
RH136644  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,216,802 - 166,216,998 (+)MAPPERmRatBN7.2
Rnor_6.05173,055,972 - 173,056,167NCBIRnor6.0
Rnor_5.05176,531,686 - 176,531,881UniSTSRnor5.0
RGSC_v3.45172,464,962 - 172,465,157UniSTSRGSC3.4
Celera5164,417,840 - 164,418,035UniSTS
RH 3.4 Map51146.2UniSTS
Cytogenetic Map5q36UniSTS
RH141852  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,244,449 - 166,244,726 (+)MAPPERmRatBN7.2
Rnor_6.05173,083,617 - 173,083,893NCBIRnor6.0
Rnor_5.05176,559,331 - 176,559,607UniSTSRnor5.0
RGSC_v3.45172,491,636 - 172,491,912UniSTSRGSC3.4
Celera5164,445,374 - 164,445,650UniSTS
RH 3.4 Map51144.9UniSTS
Cytogenetic Map5q36UniSTS
MARC_5059-5060:996690096:1  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.25166,238,085 - 166,238,696 (+)MAPPERmRatBN7.2
mRatBN7.2X107,589,759 - 107,590,068 (+)MAPPERmRatBN7.2
Rnor_6.0X115,270,534 - 115,270,842NCBIRnor6.0
Rnor_6.05173,077,254 - 173,077,864NCBIRnor6.0
Rnor_5.05176,552,968 - 176,553,578UniSTSRnor5.0
Rnor_5.0X113,722,777 - 113,723,085UniSTSRnor5.0
RGSC_v3.4X34,505,034 - 34,505,342UniSTSRGSC3.4
RGSC_v3.45172,485,359 - 172,485,969UniSTSRGSC3.4
Celera5164,439,011 - 164,439,621UniSTS
CeleraX106,987,503 - 106,987,811UniSTS
Cytogenetic MapXq14UniSTS
Cytogenetic Map5q36UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_145766 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239527 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239528 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239530 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039109295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287178 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063287179 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA817907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC105662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY544650 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DY556124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EX490221 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM031851 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FM044847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L24388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000023274   ⟹   ENSRNOP00000023274
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5166,212,829 - 166,238,876 (+)Ensembl
Rnor_6.0 Ensembl5173,052,063 - 173,078,046 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000050188   ⟹   ENSRNOP00000039105
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl5166,212,831 - 166,238,875 (+)Ensembl
Rnor_6.0 Ensembl5173,066,957 - 173,077,928 (+)Ensembl
RefSeq Acc Id: NM_145766   ⟹   NP_665709
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,152 - 171,521,143 (+)NCBI
mRatBN7.25166,212,890 - 166,238,881 (+)NCBI
Rnor_6.05173,052,063 - 173,078,049 (+)NCBI
Rnor_5.05176,527,409 - 176,553,763 (+)NCBI
RGSC_v3.45172,459,111 - 172,486,012 (+)RGD
Celera5164,414,228 - 164,439,806 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239529   ⟹   XP_006239591
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,879 - 171,521,143 (+)NCBI
mRatBN7.25166,212,761 - 166,238,883 (+)NCBI
Rnor_6.05173,051,900 - 173,078,049 (+)NCBI
Rnor_5.05176,527,409 - 176,553,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239530   ⟹   XP_006239592
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,777 - 171,521,143 (+)NCBI
mRatBN7.25166,213,514 - 166,238,883 (+)NCBI
Rnor_6.05173,052,718 - 173,078,049 (+)NCBI
Rnor_5.05176,527,409 - 176,553,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006239531   ⟹   XP_006239593
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,042 - 171,521,143 (+)NCBI
mRatBN7.25166,212,761 - 166,238,883 (+)NCBI
Rnor_6.05173,051,900 - 173,078,049 (+)NCBI
Rnor_5.05176,527,409 - 176,553,763 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039109290   ⟹   XP_038965218
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,782 - 171,521,143 (+)NCBI
mRatBN7.25166,212,761 - 166,238,883 (+)NCBI
RefSeq Acc Id: XM_039109293   ⟹   XP_038965221
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,504,409 - 171,521,143 (+)NCBI
mRatBN7.25166,221,966 - 166,238,883 (+)NCBI
RefSeq Acc Id: XM_039109294   ⟹   XP_038965222
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,500,583 - 171,521,143 (+)NCBI
mRatBN7.25166,218,322 - 166,238,883 (+)NCBI
RefSeq Acc Id: XM_039109295   ⟹   XP_038965223
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,509,645 - 171,521,143 (+)NCBI
mRatBN7.25166,227,380 - 166,238,883 (+)NCBI
RefSeq Acc Id: XM_063287178   ⟹   XP_063143248
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,782 - 171,521,143 (+)NCBI
RefSeq Acc Id: XM_063287179   ⟹   XP_063143249
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr85171,495,042 - 171,521,143 (+)NCBI
RefSeq Acc Id: NP_665709   ⟸   NM_145766
- UniProtKB: D4A3G2 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239591   ⟸   XM_006239529
- Peptide Label: isoform X3
- UniProtKB: D3ZML3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239593   ⟸   XM_006239531
- Peptide Label: isoform X3
- UniProtKB: D3ZML3 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239592   ⟸   XM_006239530
- Peptide Label: isoform X3
- UniProtKB: D3ZML3 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000023274   ⟸   ENSRNOT00000023274
Ensembl Acc Id: ENSRNOP00000039105   ⟸   ENSRNOT00000050188
RefSeq Acc Id: XP_038965218   ⟸   XM_039109290
- Peptide Label: isoform X2
- UniProtKB: A6IUR2 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038965222   ⟸   XM_039109294
- Peptide Label: isoform X6
RefSeq Acc Id: XP_038965221   ⟸   XM_039109293
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038965223   ⟸   XM_039109295
- Peptide Label: isoform X7
- UniProtKB: P46892 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_063143249   ⟸   XM_063287179
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063143248   ⟸   XM_063287178
- Peptide Label: isoform X1
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P46892-F1-model_v2 AlphaFold P46892 1-436 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694322
Promoter ID:EPDNEW_R4847
Type:initiation region
Name:Cdk11b_1
Description:cyclin-dependent kinase 11B
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.05173,052,015 - 173,052,075EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:628604 AgrOrtholog
BioCyc Gene G2FUF-38917 BioCyc
Ensembl Genes ENSRNOG00000017213 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000023274.7 UniProtKB/TrEMBL
  ENSRNOT00000050188.5 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro CDK UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CDK11/PITSLRE_STKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:252879 UniProtKB/TrEMBL
NCBI Gene 252879 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE 11A-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Cdk11b PhenoGen
PROSITE PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000017213 RatGTEx
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A6IUR2 ENTREZGENE, UniProtKB/TrEMBL
  CD11B_RAT UniProtKB/Swiss-Prot
  D3ZML3 ENTREZGENE, UniProtKB/TrEMBL
  D4A3G2 ENTREZGENE, UniProtKB/TrEMBL
  P46892 ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-02-22 Cdk11b  cyclin-dependent kinase 11B  Cdc2l1  cell division cycle 2 homolog (S.pombe)-like 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-20 Cdc2l1  cell division cycle 2 homolog (S.pombe)-like 1      Symbol and Name status set to approved 1299863 APPROVED
2003-02-27 Cdc2l1  cell division cycle 2 homolog (S.pombe)-like 1      Symbol and Name status set to provisional 70820 PROVISIONAL