CDK11B (cyclin dependent kinase 11B) - Rat Genome Database

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Gene: CDK11B (cyclin dependent kinase 11B) Pan paniscus
Analyze
Symbol: CDK11B
Name: cyclin dependent kinase 11B
RGD ID: 11981495
Description: ENCODES a protein that exhibits ATP binding (inferred); protein serine/threonine kinase activity (inferred); INVOLVED IN blastocyst development (ortholog); negative regulation of apoptotic signaling pathway (ortholog); regulation of cell growth (ortholog); ASSOCIATED WITH chromosome 1p36 deletion syndrome (ortholog); congenital myasthenic syndrome 8 (ortholog); dilated cardiomyopathy 1LL (ortholog); FOUND IN nucleus (inferred)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: CDK11A; cyclin-dependent kinase 11A; cyclin-dependent kinase 11B; LOC100987042
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,558,305 - 226,581,539 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,214,256 - 225,237,485 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01399,997 - 423,094 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,557,887 - 1,567,942 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,558,423 - 1,579,305 (-)Ensemblpanpan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
CDK11B
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21226,558,305 - 226,581,539 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11225,214,256 - 225,237,485 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01399,997 - 423,094 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111,557,887 - 1,567,942 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11,558,423 - 1,579,305 (-)Ensemblpanpan1.1panPan2
CDK11B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811,635,225 - 1,659,004 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11,635,225 - 1,659,012 (-)EnsemblGRCh38hg38GRCh38
GRCh3711,570,603 - 1,590,465 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3611,624,180 - 1,645,637 (-)NCBINCBI36Build 36hg18NCBI36
Cytogenetic Map1p36.33NCBI
HuRef1839,060 - 867,349 (-)NCBIHuRef
CHM1_111,558,156 - 1,577,529 (-)NCBICHM1_1
T2T-CHM13v2.011,069,728 - 1,093,685 (-)NCBIT2T-CHM13v2.0
Cdk11b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm394155,709,303 - 155,734,392 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl4155,709,311 - 155,734,395 (+)EnsemblGRCm39 Ensembl
GRCm384155,624,841 - 155,649,935 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl4155,624,854 - 155,649,938 (+)EnsemblGRCm38mm10GRCm38
MGSCv374154,998,978 - 155,024,041 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv364154,468,669 - 154,493,732 (+)NCBIMGSCv36mm8
Celera4157,899,879 - 157,924,805 (+)NCBICelera
Cytogenetic Map4E2NCBI
cM Map486.73NCBI
Cdk11b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr85171,495,042 - 171,521,143 (+)NCBIGRCr8
mRatBN7.25166,212,761 - 166,238,883 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl5166,212,829 - 166,238,876 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx5168,917,908 - 168,943,888 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.05170,739,324 - 170,765,307 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.05170,701,863 - 170,727,846 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.05173,051,900 - 173,078,049 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl5173,052,063 - 173,078,046 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.05176,527,409 - 176,553,763 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.45172,459,111 - 172,486,012 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera5164,414,228 - 164,439,806 (+)NCBICelera
Cytogenetic Map5q36NCBI
Cdk11b
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554869,251,242 - 9,270,218 (+)NCBIChiLan1.0ChiLan1.0
CDK11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1556,698,267 - 56,714,075 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha556,773,892 - 56,789,740 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0556,900,241 - 56,916,116 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl556,900,247 - 56,916,079 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1556,891,042 - 56,906,886 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0556,783,340 - 56,799,187 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0557,173,307 - 57,189,184 (-)NCBIUU_Cfam_GSD_1.0
CDK11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1663,804,914 - 63,819,960 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2658,234,564 - 58,249,513 (-)NCBISscrofa10.2Sscrofa10.2susScr3
LOC103225783
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.120129,848,297 - 129,873,287 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605434,303,072 - 34,328,300 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_034953281 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953302 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953307 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953309 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953317 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034953322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055099289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055099296 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055099311 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063595083 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063595086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSPPAT00000042425   ⟹   ENSPPAP00000019655
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11,558,423 - 1,579,305 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000042448   ⟹   ENSPPAP00000019678
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11,558,423 - 1,579,305 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000042458   ⟹   ENSPPAP00000019688
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11,558,423 - 1,579,305 (-)Ensembl
RefSeq Acc Id: ENSPPAT00000042460   ⟹   ENSPPAP00000019690
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
PanPan1.1 Ensembl11,558,423 - 1,579,305 (-)Ensembl
RefSeq Acc Id: XM_034953281   ⟹   XP_034809172
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,305 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,309 - 225,237,485 (+)NCBI
Mhudiblu_PPA_v01399,997 - 423,094 (-)NCBI
RefSeq Acc Id: XM_034953286   ⟹   XP_034809177
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,401 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,885 - 225,237,485 (+)NCBI
Mhudiblu_PPA_v01399,997 - 422,605 (-)NCBI
RefSeq Acc Id: XM_034953288   ⟹   XP_034809179
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,637 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,583 - 225,237,485 (+)NCBI
Mhudiblu_PPA_v01399,997 - 422,908 (-)NCBI
RefSeq Acc Id: XM_034953295   ⟹   XP_034809186
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,305 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,256 - 225,237,485 (+)NCBI
Mhudiblu_PPA_v01399,997 - 423,094 (-)NCBI
RefSeq Acc Id: XM_034953298   ⟹   XP_034809189
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,358 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,309 - 225,237,485 (+)NCBI
Mhudiblu_PPA_v01399,997 - 423,094 (-)NCBI
RefSeq Acc Id: XM_034953302   ⟹   XP_034809193
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,358 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,309 - 225,237,485 (+)NCBI
Mhudiblu_PPA_v01399,997 - 423,094 (-)NCBI
RefSeq Acc Id: XM_034953307   ⟹   XP_034809198
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,582 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,533 - 225,237,485 (+)NCBI
Mhudiblu_PPA_v01399,997 - 422,954 (-)NCBI
RefSeq Acc Id: XM_055099289   ⟹   XP_054955264
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,534 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,464 - 225,237,485 (+)NCBI
RefSeq Acc Id: XM_055099296   ⟹   XP_054955271
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,643 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,214,267 - 225,237,485 (+)NCBI
RefSeq Acc Id: XM_055099311   ⟹   XP_054955286
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,567,464 - 226,581,539 (+)NCBI
NHGRI_mPanPan11225,223,416 - 225,237,485 (+)NCBI
RefSeq Acc Id: XM_063595083   ⟹   XP_063451153
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,558,305 - 226,581,539 (+)NCBI
RefSeq Acc Id: XM_063595086   ⟹   XP_063451156
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v21226,560,028 - 226,581,539 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_034809193   ⟸   XM_034953302
- Peptide Label: isoform X4
- UniProtKB: A0A2R9AR99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809189   ⟸   XM_034953298
- Peptide Label: isoform X3
- UniProtKB: A0A2R9AR99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809186   ⟸   XM_034953295
- Peptide Label: isoform X2
- UniProtKB: A0A2R9AR99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809172   ⟸   XM_034953281
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AR99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809198   ⟸   XM_034953307
- Peptide Label: isoform X5
- UniProtKB: A0A2R9AR89 (UniProtKB/TrEMBL),   A0A2R9AR99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809179   ⟸   XM_034953288
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AR99 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_034809177   ⟸   XM_034953286
- Peptide Label: isoform X1
- UniProtKB: A0A2R9AR99 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSPPAP00000019655   ⟸   ENSPPAT00000042425
RefSeq Acc Id: ENSPPAP00000019690   ⟸   ENSPPAT00000042460
RefSeq Acc Id: ENSPPAP00000019678   ⟸   ENSPPAT00000042448
RefSeq Acc Id: ENSPPAP00000019688   ⟸   ENSPPAT00000042458
RefSeq Acc Id: XP_054955271   ⟸   XM_055099296
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054955264   ⟸   XM_055099289
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054955286   ⟸   XM_055099311
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063451153   ⟸   XM_063595083
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063451156   ⟸   XM_063595086
- Peptide Label: isoform X6
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000032936 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000042425.1 UniProtKB/TrEMBL
  ENSPPAT00000042448.1 UniProtKB/TrEMBL
  ENSPPAT00000042458.1 UniProtKB/TrEMBL
  ENSPPAT00000042460.1 UniProtKB/TrEMBL
Gene3D-CATH Transferase(Phosphotransferase) domain 1 UniProtKB/TrEMBL
InterPro CDK11/PITSLRE_STKc UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene LOC100987042 ENTREZGENE
PANTHER CELL DIVISION PROTEIN KINASE UniProtKB/TrEMBL
  CYCLIN-DEPENDENT KINASE 11A-RELATED UniProtKB/TrEMBL
Pfam Pkinase UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A2R9AR89 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AR99 ENTREZGENE, UniProtKB/TrEMBL
  A0A2R9AV54_PANPA UniProtKB/TrEMBL
  A0A2R9AV89_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2020-07-01 CDK11B  cyclin dependent kinase 11B  LOC100987042  cyclin-dependent kinase 11B  Symbol and/or name change 5135510 APPROVED