Dynlt1 (dynein light chain Tctex-type 1) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Advanced Search (OLGA)
Gene: Dynlt1 (dynein light chain Tctex-type 1) Rattus norvegicus
Analyze
Symbol: Dynlt1
Name: dynein light chain Tctex-type 1
RGD ID: 620261
Description: Enables transmembrane transporter binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; neuron projection development; and positive regulation of Rac protein signal transduction. Located in axonal growth cone; lamellipodium; and neuronal cell body. Orthologous to human DYNLT1 (dynein light chain Tctex-type 1); PARTICIPATES IN mitochondria transport pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: activator of G-protein signaling 2; AGS2; t-complex testis expressed 1; T-complex testis-specific protein 1 homolog; Tctex1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,292,093 - 49,299,051 (-)NCBIGRCr8
mRatBN7.2146,887,017 - 46,893,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,887,017 - 46,893,881 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx147,435,976 - 47,442,799 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,423,238 - 53,430,061 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,511,411 - 47,518,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,206,892 - 47,213,785 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,206,895 - 47,213,749 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,510,103 - 48,516,996 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,097,174 - 41,103,997 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1141,100,118 - 41,106,942 (-)NCBI
Celera142,574,662 - 42,581,485 (-)NCBICelera
Cytogenetic Map1q11NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Cytoplasmic dynein. Allan VJ, Biochem Soc Trans. 2011 Oct;39(5):1169-78. doi: 10.1042/BST0391169.
2. The dynein light chain Tctex-1 has a dynein-independent role in actin remodeling during neurite outgrowth. Chuang JZ, etal., Dev Cell. 2005 Jul;9(1):75-86.
3. MAP4 mechanism that stabilizes mitochondrial permeability transition in hypoxia: microtubule enhancement and DYNLT1 interaction with VDAC1. Fang YD, etal., PLoS One. 2011;6(12):e28052. doi: 10.1371/journal.pone.0028052. Epub 2011 Dec 2.
4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
5. A tctex1-Ca2+ channel complex for selective surface expression of Ca2+ channels in neurons. Lai M, etal., Nat Neurosci. 2005 Apr;8(4):435-42. Epub 2005 Mar 13.
6. A direct interaction between cytoplasmic dynein and kinesin I may coordinate motor activity. Ligon LA, etal., J Biol Chem. 2004 Apr 30;279(18):19201-8. Epub 2004 Feb 24.
7. Sensory neuron proteins interact with the intracellular domains of sodium channel NaV1.8. Malik-Hall M, etal., Brain Res Mol Brain Res. 2003 Feb 20;110(2):298-304.
8. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
9. Interaction of Doc2 with tctex-1, a light chain of cytoplasmic dynein. Implication in dynein-dependent vesicle transport. Nagano F, etal., J Biol Chem 1998 Nov 13;273(46):30065-8.
10. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
11. GOA pipeline RGD automated data pipeline
12. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
13. Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease. Ribeiro FM, etal., Hum Mol Genet. 2014 Apr 15;23(8):2030-42. doi: 10.1093/hmg/ddt598. Epub 2013 Nov 26.
14. Rhodopsin's carboxy-terminal cytoplasmic tail acts as a membrane receptor for cytoplasmic dynein by binding to the dynein light chain Tctex-1. Tai AW, etal., Cell. 1999 Jun 25;97(7):877-87.
15. Identification of hypertension-related genes through an integrated genomic-transcriptomic approach. Yagil C, etal., Circ Res. 2005 Apr 1;96(6):617-25. Epub 2005 Feb 24.
Additional References at PubMed
PMID:11157096   PMID:12477932   PMID:17965411   PMID:18647839   PMID:21262767   PMID:24170091   PMID:25205765  


Genomics

Comparative Map Data
Dynlt1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,292,093 - 49,299,051 (-)NCBIGRCr8
mRatBN7.2146,887,017 - 46,893,956 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl146,887,017 - 46,893,881 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx147,435,976 - 47,442,799 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0153,423,238 - 53,430,061 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0147,511,411 - 47,518,234 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0147,206,892 - 47,213,785 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl147,206,895 - 47,213,749 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0148,510,103 - 48,516,996 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4141,097,174 - 41,103,997 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1141,100,118 - 41,106,942 (-)NCBI
Celera142,574,662 - 42,581,485 (-)NCBICelera
Cytogenetic Map1q11NCBI
DYNLT1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh386158,636,474 - 158,644,743 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl6158,636,474 - 158,644,743 (-)EnsemblGRCh38hg38GRCh38
GRCh376159,057,506 - 159,065,775 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 366158,977,497 - 158,985,728 (-)NCBINCBI36Build 36hg18NCBI36
Build 346159,027,914 - 159,036,149NCBI
Celera6159,705,500 - 159,713,799 (-)NCBICelera
Cytogenetic Map6q25.3NCBI
HuRef6156,528,404 - 156,536,700 (-)NCBIHuRef
CHM1_16159,320,069 - 159,328,365 (-)NCBICHM1_1
T2T-CHM13v2.06159,881,698 - 159,889,969 (-)NCBIT2T-CHM13v2.0
Dynlt1b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39176,697,511 - 6,703,695 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl176,697,511 - 6,703,695 (+)EnsemblGRCm39 Ensembl
GRCm38176,429,530 - 6,440,500 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl176,306,340 - 6,317,500 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl176,430,112 - 6,436,296 (+)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl176,646,602 - 6,655,900 (-)EnsemblGRCm38mm10GRCm38
GRCm38.p6 Ensembl176,601,671 - 6,609,774 (+)EnsemblGRCm38mm10GRCm38
MGSCv37176,429,260 - 6,435,444 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36176,412,303 - 6,418,495 (-)NCBIMGSCv36mm8
Cytogenetic Map17A1NCBI
cM Map173.97NCBI
Dynlt1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554393,833,525 - 3,842,393 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554393,833,525 - 3,842,393 (+)NCBIChiLan1.0ChiLan1.0
DYNLT1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v25178,744,093 - 178,752,350 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan16176,647,991 - 176,656,267 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v06156,530,068 - 156,538,346 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.16161,544,128 - 161,552,391 (-)NCBIpanpan1.1PanPan1.1panPan2
DYNLT1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1148,058,804 - 48,066,389 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl148,058,804 - 48,066,609 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha148,903,907 - 48,911,551 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0148,244,957 - 48,252,653 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl148,244,957 - 48,253,247 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1148,121,663 - 48,129,302 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0147,992,244 - 47,999,994 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0148,551,864 - 48,559,503 (-)NCBIUU_Cfam_GSD_1.0
Dynlt1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404946143,077,230 - 143,083,807 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648910,329,223 - 10,335,782 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648910,329,223 - 10,335,758 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DYNLT1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl18,556,059 - 8,563,676 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.118,556,083 - 8,562,865 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2110,385,073 - 10,391,588 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DYNLT1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11386,210,462 - 86,218,002 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1386,210,465 - 86,217,956 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604058,592,316 - 58,599,872 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dynlt1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_004624929968,823 - 976,414 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_004624929969,294 - 976,420 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Dynlt1
16 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:27
Count of miRNA genes:26
Interacting mature miRNAs:26
Transcripts:ENSRNOT00000024656
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1331732Srn4Serum renin concentration QTL 44.467renin activity (VT:0005581)plasma renin activity level (CMO:0000116)13523959878430678Rat
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1357397Bw41Body weight QTL 414.190.0001body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
1331792Rf29Renal function QTL 294.589urine potassium amount (VT:0010539)urine potassium level (CMO:0000128)13523959878430678Rat
2313062Bmd73Bone mineral density QTL 733.90.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)11148131282174945Rat
8552900Pigfal1Plasma insulin-like growth factor 1 level QTL 17.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
1554320Bmd1Bone mineral density QTL 112.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)150910886060548Rat
1354643Foco2Food consumption QTL 27.170.0001eating behavior trait (VT:0001431)food intake rate (CMO:0000427)13344984878449848Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
2313065Bss67Bone structure and strength QTL 673.10.0001tibia area (VT:1000281)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
7421626Bp360Blood pressure QTL 3600.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1439328949393289Rat
1357400Bw62Body weight QTL624.05inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)12234064767340647Rat
1357401Bw43Body weight QTL 433.75body mass (VT:0001259)body weight (CMO:0000012)12234064749361612Rat
2313069Bss68Bone structure and strength QTL 682.90.0001tibia size trait (VT:0100001)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
631494Bp95Blood pressure QTL 95400.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)11620621049268520Rat
2313075Bss66Bone structure and strength QTL 663.40.0001tibia length (VT:0004357)tibia length (CMO:0000450)11148131282174945Rat
5684998Bss101Bone structure and strength QTL 1013.6tibia strength trait (VT:1000284)tibia ultimate force (CMO:0001734)11543162149361612Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
5684999Bss102Bone structure and strength QTL 1025.57e-07tibia strength trait (VT:1000284)tibia stiffness (CMO:0001735)11543162149361612Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
1300167Hrtrt2Heart rate QTL 24.35heart pumping trait (VT:2000009)heart rate (CMO:0000002)11148131275088344Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
2313077Bss69Bone structure and strength QTL 693.50.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)11148131282174945Rat
1331778Rf28Renal function QTL 284.66urine potassium amount (VT:0010539)urine potassium excretion rate (CMO:0000761)14580314078430678Rat
1578756Iddm22Insulin dependent diabetes mellitus QTL 222.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)11183518156835181Rat
631508Sald1Serum aldosterone level QTL 13.7blood aldosterone amount (VT:0005346)serum aldosterone level (CMO:0000487)1985600154856001Rat
1331785Rf27Renal function QTL 274.643urine sodium amount (VT:0006274)urine sodium level (CMO:0000129)12887978078430678Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
724520Bp145Blood pressure QTL 1452.10.0024arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)12078482865784828Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
2313092Bmd72Bone mineral density QTL 722.50.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)11148131282174945Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
2313097Bss70Bone structure and strength QTL 703.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)11148131282174945Rat
9589820Insglur3Insulin/glucose ratio QTL 310.750.001blood insulin amount (VT:0001560)calculated plasma insulin level (CMO:0002170)13483685879836858Rat
738020Pia8Pristane induced arthritis QTL 84.7joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)1165833076Rat
1354599Bw29Body weight QTL 293.460.001body mass (VT:0001259)body weight (CMO:0000012)13344984878449848Rat
2302038Pia31Pristane induced arthritis QTL 315.50.001blood autoantibody amount (VT:0003725)serum immunoglobulin M-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002111)11099206555992065Rat
8552948Pigfal11Plasma insulin-like growth factor 1 level QTL 114.7blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)13483685879836858Rat
634353Rends2Renal damage susceptibility QTL 20.05kidney blood vessel morphology trait (VT:0000530)organ lesion measurement (CMO:0000677)11933357156983283Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat

Markers in Region
D1Ztm7  
Rat AssemblyChrPosition (strand)SourceJBrowse
Rnor_6.0147,200,222 - 47,200,455NCBIRnor6.0
Rnor_5.0148,503,432 - 48,503,665UniSTSRnor5.0
RGSC_v3.4141,090,502 - 41,090,735UniSTSRGSC3.4
Celera142,567,990 - 42,568,223UniSTS
Cytogenetic Map1q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000024656   ⟹   ENSRNOP00000024656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl146,887,017 - 46,893,881 (-)Ensembl
Rnor_6.0 Ensembl147,206,895 - 47,213,749 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000107400   ⟹   ENSRNOP00000077983
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl146,887,017 - 46,893,551 (-)Ensembl
RefSeq Acc Id: NM_031318   ⟹   NP_112608
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,292,094 - 49,298,917 (-)NCBI
mRatBN7.2146,887,018 - 46,893,841 (-)NCBI
Rnor_6.0147,206,894 - 47,213,717 (-)NCBI
Rnor_5.0148,510,103 - 48,516,996 (-)NCBI
RGSC_v3.4141,097,174 - 41,103,997 (-)RGD
Celera142,574,662 - 42,581,485 (-)RGD
Sequence:
RefSeq Acc Id: XM_006227901   ⟹   XP_006227963
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,292,093 - 49,299,051 (-)NCBI
mRatBN7.2146,887,017 - 46,893,956 (-)NCBI
Rnor_6.0147,206,892 - 47,213,785 (-)NCBI
Rnor_5.0148,510,103 - 48,516,996 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_112608 (Get FASTA)   NCBI Sequence Viewer  
  XP_006227963 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66879 (Get FASTA)   NCBI Sequence Viewer  
  BAA34532 (Get FASTA)   NCBI Sequence Viewer  
  CAC18728 (Get FASTA)   NCBI Sequence Viewer  
  EDL83717 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000024656.4
  ENSRNOP00000077983.1
GenBank Protein Q9Z336 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_112608   ⟸   NM_031318
- UniProtKB: Q9Z336 (UniProtKB/Swiss-Prot),   B2RYR9 (UniProtKB/TrEMBL),   A0A8L2QD70 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006227963   ⟸   XM_006227901
- Peptide Label: isoform X1
- Sequence:
Ensembl Acc Id: ENSRNOP00000024656   ⟸   ENSRNOT00000024656
Ensembl Acc Id: ENSRNOP00000077983   ⟸   ENSRNOT00000107400

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9Z336-F1-model_v2 AlphaFold Q9Z336 1-113 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13689607
Promoter ID:EPDNEW_R131
Type:initiation region
Name:Dynlt1_1
Description:dynein light chain Tctex-type 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0147,213,749 - 47,213,809EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:620261 AgrOrtholog
BioCyc Gene G2FUF-61616 BioCyc
Ensembl Genes ENSRNOG00000018207 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000024656.4 UniProtKB/TrEMBL
  ENSRNOT00000107400.1 UniProtKB/TrEMBL
Gene3D-CATH 3.30.1140.40 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:6919674 IMAGE-MGC_LOAD
InterPro Tctex-1-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tctex-1-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:83462 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:188810 IMAGE-MGC_LOAD
NCBI Gene 83462 ENTREZGENE
PANTHER DYNEIN LIGHT CHAIN TCTEX-TYPE 1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR21255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Tctex-1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Dynlt1 PhenoGen
RatGTEx ENSRNOG00000018207 RatGTEx
UniProt A0A8I5Y6Y0_RAT UniProtKB/TrEMBL
  A0A8L2QD70 ENTREZGENE, UniProtKB/TrEMBL
  B2RYR9 ENTREZGENE, UniProtKB/TrEMBL
  DYLT1_RAT UniProtKB/Swiss-Prot, ENTREZGENE


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2008-02-22 Dynlt1  dynein light chain Tctex-type 1  Tctex1  t-complex testis expressed 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2004-09-10 Tctex1  t-complex testis expressed 1      Symbol and Name status set to approved 1299863 APPROVED
2002-08-07 Tctex1  t-complex testis expressed 1      Symbol and Name status set to provisional 70820 PROVISIONAL

RGD Curation Notes
Note Type Note Reference
gene_disease identified as a possible hypertension gene 1559295
gene_expression ubiquitously expressed 634245
gene_physical_interaction binds to Doc2 634245
gene_protein 113 amino acids; 12.4 kDa 634245