Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Fez2 | Rat | (1->4)-beta-D-glucan | multiple interactions | ISO | Fez2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of FEZ2 mRNA | CTD | PMID:36331819 | Fez2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Fez2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FEZ2 mRNA | CTD | PMID:22206623 | Fez2 | Rat | 2,2',5,5'-tetrachlorobiphenyl | decreases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:23829299 | Fez2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Fez2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of FEZ2 mRNA | CTD | PMID:21570461 | Fez2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of FEZ2 mRNA | CTD | PMID:34747641 | Fez2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of FEZ2 mRNA | CTD | PMID:21346803 | Fez2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of FEZ2 mRNA | CTD | PMID:30047161 | Fez2 | Rat | aflatoxin B1 | decreases methylation | ISO | FEZ2 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of FEZ2 exon | CTD | PMID:30157460 | Fez2 | Rat | all-trans-retinoic acid | decreases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of FEZ2 mRNA | CTD | PMID:33167477 | Fez2 | Rat | ammonium chloride | affects expression | EXP | | 6480464 | Ammonium Chloride affects the expression of FEZ2 mRNA | CTD | PMID:16483693 | Fez2 | Rat | antimycin A | decreases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Antimycin A results in decreased expression of FEZ2 mRNA | CTD | PMID:33512557 | Fez2 | Rat | antirheumatic drug | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of FEZ2 mRNA | CTD | PMID:24449571 | Fez2 | Rat | aristolochic acid A | decreases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of FEZ2 mRNA | CTD | PMID:33212167 | Fez2 | Rat | benzo[a]pyrene | affects methylation | ISO | FEZ2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of FEZ2 3' UTR and Benzo(a)pyrene affects the methylation of FEZ2 promoter | CTD | PMID:27901495 | Fez2 | Rat | benzo[b]fluoranthene | increases expression | ISO | Fez2 (Mus musculus) | 6480464 | benzo(b)fluoranthene results in increased expression of FEZ2 mRNA | CTD | PMID:26377693 | Fez2 | Rat | beta-lapachone | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | beta-lapachone results in increased expression of FEZ2 mRNA | CTD | PMID:38218311 | Fez2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of FEZ2 mRNA | CTD | PMID:25181051 | Fez2 | Rat | bisphenol A | decreases methylation | ISO | FEZ2 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of FEZ2 gene | CTD | PMID:31601247 | Fez2 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of FEZ2 mRNA | CTD | PMID:34947998 | Fez2 | Rat | bisphenol A | affects expression | ISO | FEZ2 (Homo sapiens) | 6480464 | bisphenol A affects the expression of FEZ2 mRNA | CTD | PMID:30903817 | Fez2 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of FEZ2 mRNA | CTD | PMID:30816183 and PMID:32528016 | Fez2 | Rat | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of FEZ2 mRNA | CTD | PMID:24136188 | Fez2 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of FEZ2 promoter | CTD | PMID:22457795 | Fez2 | Rat | carbamazepine | affects expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Carbamazepine affects the expression of FEZ2 mRNA | CTD | PMID:25979313 | Fez2 | Rat | chlordecone | decreases expression | ISO | Fez2 (Mus musculus) | 6480464 | Chlordecone results in decreased expression of FEZ2 mRNA | CTD | PMID:29980752 | Fez2 | Rat | clofibric acid | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of FEZ2 mRNA | CTD | PMID:17602206 | Fez2 | Rat | cobalt dichloride | increases expression | ISO | Fez2 (Mus musculus) | 6480464 | cobaltous chloride results in increased expression of FEZ2 mRNA | CTD | PMID:21139344 | Fez2 | Rat | cobalt dichloride | decreases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | cobaltous chloride results in decreased expression of FEZ2 mRNA | CTD | PMID:19320972 | Fez2 | Rat | cobalt dichloride | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of FEZ2 mRNA | CTD | PMID:19376846 | Fez2 | Rat | coumarin | decreases phosphorylation | ISO | FEZ2 (Homo sapiens) | 6480464 | coumarin results in decreased phosphorylation of FEZ2 protein | CTD | PMID:35688186 | Fez2 | Rat | cyclosporin A | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of FEZ2 mRNA | CTD | PMID:25562108 | Fez2 | Rat | cyproconazole | increases expression | ISO | Fez2 (Mus musculus) | 6480464 | cyproconazole results in increased expression of FEZ2 mRNA | CTD | PMID:22334560 | Fez2 | Rat | dicrotophos | decreases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of FEZ2 mRNA | CTD | PMID:28302478 | Fez2 | Rat | diuron | decreases expression | EXP | | 6480464 | Diuron results in decreased expression of FEZ2 mRNA | CTD | PMID:21551480 | Fez2 | Rat | doxorubicin | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Doxorubicin results in increased expression of FEZ2 mRNA | CTD | PMID:29803840 | Fez2 | Rat | epoxiconazole | increases expression | ISO | Fez2 (Mus musculus) | 6480464 | epoxiconazole results in increased expression of FEZ2 mRNA | CTD | PMID:22334560 | Fez2 | Rat | ethylbenzene | multiple interactions | ISO | FEZ2 (Homo sapiens) | 6480464 | [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of FEZ2 mRNA and [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of FEZ2 gene | CTD | PMID:26018793 | Fez2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of FEZ2 mRNA | CTD | PMID:24136188 | Fez2 | Rat | folic acid | multiple interactions | ISO | Fez2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FEZ2 mRNA | CTD | PMID:22206623 | Fez2 | Rat | FR900359 | decreases phosphorylation | ISO | FEZ2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of FEZ2 protein | CTD | PMID:37730182 | Fez2 | Rat | inulin | multiple interactions | ISO | Fez2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of FEZ2 mRNA | CTD | PMID:36331819 | Fez2 | Rat | isotretinoin | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Isotretinoin results in increased expression of FEZ2 mRNA | CTD | PMID:20436886 | Fez2 | Rat | manganese(II) chloride | increases expression | EXP | | 6480464 | manganese chloride results in increased expression of FEZ2 mRNA | CTD | PMID:28801915 | Fez2 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of FEZ2 mRNA | CTD | PMID:30047161 | Fez2 | Rat | N-nitrosodiethylamine | multiple interactions | EXP | | 6480464 | [Diethylnitrosamine co-treated with Clofibric Acid] affects the expression of FEZ2 mRNA | CTD | PMID:17602206 | Fez2 | Rat | N-nitrosodimethylamine | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Dimethylnitrosamine results in increased expression of FEZ2 mRNA | CTD | PMID:17547211 | Fez2 | Rat | nickel sulfate | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | nickel sulfate results in increased expression of FEZ2 mRNA | CTD | PMID:22714537 | Fez2 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of FEZ2 mRNA | CTD | PMID:25729387 | Fez2 | Rat | ozone | multiple interactions | ISO | FEZ2 (Homo sapiens) | 6480464 | [Air Pollutants results in increased abundance of Ozone] which affects the expression of FEZ2 mRNA | CTD | PMID:35430440 | Fez2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of FEZ2 mRNA | CTD | PMID:33387578 | Fez2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Fez2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of FEZ2 mRNA more ... | CTD | PMID:36331819 | Fez2 | Rat | phenobarbital | multiple interactions | ISO | Fez2 (Mus musculus) | 6480464 | NR1I3 protein affects the reaction [Phenobarbital results in increased expression of FEZ2 mRNA] | CTD | PMID:19482888 | Fez2 | Rat | phenobarbital | affects expression | ISO | Fez2 (Mus musculus) | 6480464 | Phenobarbital affects the expression of FEZ2 mRNA | CTD | PMID:23091169 | Fez2 | Rat | phenobarbital | increases expression | ISO | Fez2 (Mus musculus) | 6480464 | Phenobarbital results in increased expression of FEZ2 mRNA | CTD | PMID:19482888 | Fez2 | Rat | pirinixic acid | increases expression | ISO | Fez2 (Mus musculus) | 6480464 | pirinixic acid results in increased expression of FEZ2 mRNA | CTD | PMID:23811191 | Fez2 | Rat | pregnenolone 16alpha-carbonitrile | increases expression | EXP | | 6480464 | Pregnenolone Carbonitrile results in increased expression of FEZ2 mRNA | CTD | PMID:30047161 | Fez2 | Rat | propiconazole | increases expression | ISO | Fez2 (Mus musculus) | 6480464 | propiconazole results in increased expression of FEZ2 mRNA | CTD | PMID:21278054 and PMID:22334560 | Fez2 | Rat | quercetin | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Quercetin results in increased expression of FEZ2 mRNA | CTD | PMID:21632981 | Fez2 | Rat | resveratrol | multiple interactions | ISO | FEZ2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of FEZ2 mRNA | CTD | PMID:23557933 | Fez2 | Rat | rotenone | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Rotenone results in increased expression of FEZ2 mRNA | CTD | PMID:33512557 | Fez2 | Rat | sodium arsenite | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of FEZ2 mRNA | CTD | PMID:38568856 | Fez2 | Rat | tebufenpyrad | decreases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | 4-chloro-N-((4-(1 and 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of FEZ2 mRNA | CTD | PMID:33512557 | Fez2 | Rat | testosterone | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Testosterone results in increased expression of FEZ2 mRNA | CTD | PMID:21475673 | Fez2 | Rat | tetrachloromethane | decreases expression | EXP | | 6480464 | Carbon Tetrachloride results in decreased expression of FEZ2 mRNA | CTD | PMID:31150632 | Fez2 | Rat | thiram | increases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Thiram results in increased expression of FEZ2 mRNA | CTD | PMID:38568856 | Fez2 | Rat | titanium dioxide | increases methylation | ISO | Fez2 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of FEZ2 promoter | CTD | PMID:35295148 | Fez2 | Rat | titanium dioxide | decreases methylation | ISO | Fez2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of FEZ2 gene | CTD | PMID:35295148 | Fez2 | Rat | toluene | multiple interactions | ISO | FEZ2 (Homo sapiens) | 6480464 | [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in decreased expression of FEZ2 mRNA and [Toluene co-treated with ethylbenzene co-treated with Xylenes] results in increased methylation of FEZ2 gene | CTD | PMID:26018793 | Fez2 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in increased expression of FEZ2 mRNA | CTD | PMID:25729387 | Fez2 | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of FEZ2 gene | CTD | PMID:27618143 | Fez2 | Rat | tunicamycin | decreases expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Tunicamycin results in decreased expression of FEZ2 mRNA | CTD | PMID:22378314 | Fez2 | Rat | valproic acid | affects expression | ISO | FEZ2 (Homo sapiens) | 6480464 | Valproic Acid affects the expression of FEZ2 mRNA | CTD | PMID:25979313 | Fez2 | Rat | vinclozolin | increases expression | EXP | | 6480464 | vinclozolin results in increased expression of FEZ2 mRNA | CTD | PMID:23869203 | |