Fez2 (fasciculation and elongation protein zeta 2) - Rat Genome Database

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Gene: Fez2 (fasciculation and elongation protein zeta 2) Rattus norvegicus
Analyze
Symbol: Fez2
Name: fasciculation and elongation protein zeta 2
RGD ID: 619709
Description: Predicted to be involved in negative regulation of autophagosome assembly. Predicted to be active in axon and cytoplasm. Orthologous to human FEZ2 (fasciculation and elongation protein zeta 2); INTERACTS WITH 2,2',5,5'-tetrachlorobiphenyl; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: fasciculation and elongation protein zeta 2 (zygin II); fasciculation and elongation protein zeta-2; MGC112579; synaptotagmin interacting protein zyginII; Zrp; zygin II; zygin-2; zygin-related protein; zygin-related protein types I/II
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8622,406,685 - 22,446,745 (+)NCBIGRCr8
mRatBN7.2616,654,572 - 16,694,628 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,654,614 - 16,694,626 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx616,963,214 - 17,002,425 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0617,285,419 - 17,324,634 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,769,136 - 16,808,168 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06963,903 - 1,003,955 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6963,907 - 1,004,001 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06955,729 - 995,477 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.461,145,261 - 1,184,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.161,145,359 - 1,184,406 (-)NCBI
Celera616,298,245 - 16,337,422 (+)NCBICelera
Cytogenetic Map6q12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
axon  (IBA)
cytoplasm  (IBA)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. mRNA expression of membrane-fusion-related proteins in rat parotid gland. Imai A, etal., Arch Oral Biol 2001 Oct;46(10):955-62.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. Electronic Transfer of LocusLink and RefSeq Data NCBI rat LocusLink and RefSeq merged data July 26, 2002
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:14697253   PMID:25495476  


Genomics

Comparative Map Data
Fez2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8622,406,685 - 22,446,745 (+)NCBIGRCr8
mRatBN7.2616,654,572 - 16,694,628 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl616,654,614 - 16,694,626 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx616,963,214 - 17,002,425 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0617,285,419 - 17,324,634 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0616,769,136 - 16,808,168 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.06963,903 - 1,003,955 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl6963,907 - 1,004,001 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.06955,729 - 995,477 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.461,145,261 - 1,184,406 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.161,145,359 - 1,184,406 (-)NCBI
Celera616,298,245 - 16,337,422 (+)NCBICelera
Cytogenetic Map6q12NCBI
FEZ2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38236,552,258 - 36,598,168 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl236,531,805 - 36,646,087 (-)EnsemblGRCh38hg38GRCh38
GRCh37236,779,401 - 36,825,311 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36236,632,905 - 36,678,836 (-)NCBINCBI36Build 36hg18NCBI36
Build 34236,691,056 - 36,736,886NCBI
Celera236,620,493 - 36,666,401 (-)NCBICelera
Cytogenetic Map2p22.2NCBI
HuRef236,519,688 - 36,565,600 (-)NCBIHuRef
CHM1_1236,708,760 - 36,754,691 (-)NCBICHM1_1
T2T-CHM13v2.0236,556,883 - 36,604,833 (-)NCBIT2T-CHM13v2.0
Fez2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391778,676,641 - 78,725,581 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1778,676,641 - 78,725,581 (-)EnsemblGRCm39 Ensembl
GRCm381778,369,212 - 78,418,152 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1778,369,212 - 78,418,152 (-)EnsemblGRCm38mm10GRCm38
MGSCv371778,777,225 - 78,817,443 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361778,282,943 - 78,323,161 (-)NCBIMGSCv36mm8
Celera1782,679,824 - 82,720,044 (-)NCBICelera
Cytogenetic Map17E2- E3NCBI
cM Map1748.57NCBI
Fez2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_0049554414,421,936 - 4,456,070 (-)NCBIChiLan1.0ChiLan1.0
FEZ2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21289,879,167 - 89,925,812 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A89,883,152 - 89,929,788 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A36,581,436 - 36,628,054 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A37,344,067 - 37,390,521 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A37,344,973 - 37,390,525 (-)Ensemblpanpan1.1panPan2
FEZ2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11729,043,449 - 29,086,104 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1729,044,355 - 29,086,100 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1728,857,192 - 28,899,869 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01729,693,351 - 29,736,034 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1729,693,351 - 29,736,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11728,914,863 - 28,957,685 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01728,982,684 - 29,025,379 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01729,201,941 - 29,244,683 (-)NCBIUU_Cfam_GSD_1.0
Fez2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629242,910,819 - 42,956,780 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366631,576,269 - 1,623,296 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366631,576,311 - 1,637,363 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FEZ2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl3103,566,228 - 103,615,769 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.13103,566,214 - 103,612,855 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.23110,211,643 - 110,257,184 (+)NCBISscrofa10.2Sscrofa10.2susScr3
FEZ2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11470,822,793 - 70,899,025 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1470,822,885 - 70,865,129 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604541,062,030 - 41,136,419 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Fez2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473818,216,715 - 18,260,729 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473818,217,238 - 18,260,096 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Fez2
389 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:57
Count of miRNA genes:54
Interacting mature miRNAs:56
Transcripts:ENSRNOT00000042735
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
8552962Pigfal16Plasma insulin-like growth factor 1 level QTL 169.4blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)6141223769Rat
1549905Stresp10Stress response QTL 106.830.0066stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)6127574569Rat
8693699Alc37Alcohol consumption QTL 372.60.224drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)6796416721301982Rat
10401812Kidm54Kidney mass QTL 54kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1331743Uae28Urinary albumin excretion QTL 284.5urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)6134235784Rat
2292589Emca10Estrogen-induced mammary cancer QTL 100.048mammary gland integrity trait (VT:0010552)post-insult time to mammary tumor formation (CMO:0000345)61653614061536140Rat
10401800Kidm49Kidney mass QTL 49kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)61436878859368788Rat
1300164Rf15Renal function QTL 153.12renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449754641141Rat
9589129Insul24Insulin level QTL 2419.060.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)6141223769Rat
1578758Tcas9Tongue tumor susceptibility QTL 93.29tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)6137618905Rat
4145119Mcs25Mammary carcinoma susceptibility QTL 250.0001mammary gland integrity trait (VT:0010552)ratio of deaths to total study population during a period of time (CMO:0001023)610894415110548006Rat
7411603Foco13Food consumption QTL 135.50.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6141223769Rat
1598843Cm63Cardiac mass QTL 632.6heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)6139036266Rat
738024Sach5Saccharine consumption QTL 53.90.00039consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)6143394190Rat
7411542Bw127Body weight QTL 1275.50.001body mass (VT:0001259)body weight gain (CMO:0000420)6141223769Rat
2293706Bmd20Bone mineral density QTL 204.30.0002femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)6507449719988050Rat
9589048Scfw3Subcutaneous fat weight QTL 34.570.001subcutaneous adipose mass (VT:1000472)abdominal subcutaneous fat pad weight (CMO:0002069)6141223769Rat
2292616Ept15Estrogen-induced pituitary tumorigenesis QTL 154.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6984331220338915Rat
738023Alc17Alcohol consumption QTL 173.10.003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)6127574569Rat
1354616Despr12Despair related QTL 120.0012locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)6127574569Rat
1576309Emca7Estrogen-induced mammary cancer QTL 74mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)615107216107351382Rat
2293709Bss23Bone structure and strength QTL 235.180.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)6142487980Rat
2293650Bss31Bone structure and strength QTL 315.050.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)6142487980Rat
7411584Foco4Food consumption QTL 44.30.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)6142838846Rat
1578665Bss16Bone structure and strength QTL 164.4femur morphology trait (VT:0000559)bone trabecular cross-sectional area (CMO:0002311)61173566972593685Rat
2300176Bmd51Bone mineral density QTL 5111.70.0001femur mineral mass (VT:0010011)bone mineral density (CMO:0001226)6127574569Rat
1300128Rf16Renal function QTL 163.89renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)6507449734434305Rat
1578668Bmd14Bone mineral density QTL 143.8femur mineral mass (VT:0010011)total volumetric bone mineral density (CMO:0001728)61173566972593685Rat
2301972Bp325Blood pressure QTL 3254.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)6172227641Rat
2293656Bss28Bone structure and strength QTL 286.790.0001femur morphology trait (VT:0000559)femur midshaft cortical cross-sectional area (CMO:0001663)6142487980Rat
1358190Ept1Estrogen-induced pituitary tumorigenesis QTL 14.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)6984331220338915Rat
1359023Bp272Blood pressure QTL 2722.5arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)61653614027261739Rat
1354664Slep2Serum leptin concentration QTL 24.49blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)61653614071636405Rat
2300190Bmd52Bone mineral density QTL 5211.20.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)6127574569Rat
8693690Alc35Alcohol consumption QTL 352.20.606drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)6796416721301982Rat

Markers in Region
D6Rat179  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,672,665 - 16,672,914 (-)MAPPERmRatBN7.2
Rnor_6.06985,684 - 985,932NCBIRnor6.0
Rnor_5.06977,509 - 977,757UniSTSRnor5.0
RGSC_v3.461,166,225 - 1,166,473UniSTSRGSC3.4
RGSC_v3.161,165,971 - 1,166,643RGD
Celera616,316,207 - 16,316,455UniSTS
FHH x ACI Map618.28UniSTS
FHH x ACI Map618.28RGD
Cytogenetic Map6q11UniSTS
RH134470  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2616,694,407 - 16,694,608 (-)MAPPERmRatBN7.2
Rnor_6.06963,924 - 964,124NCBIRnor6.0
Rnor_5.06955,749 - 955,949UniSTSRnor5.0
RGSC_v3.461,144,535 - 1,144,735UniSTSRGSC3.4
Celera616,337,948 - 16,338,148UniSTS
Cytogenetic Map6q11UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001414905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_053600 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006239639 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063262567 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010052153 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_592821 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB076183 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB080086 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF120111 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC100060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB725415 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473947 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK359698 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000006 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U64689 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000042735   ⟹   ENSRNOP00000049923
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,654,614 - 16,693,882 (+)Ensembl
Rnor_6.0 Ensembl6964,551 - 1,004,001 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082071   ⟹   ENSRNOP00000075253
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,654,682 - 16,694,626 (+)Ensembl
Rnor_6.0 Ensembl6963,907 - 1,003,905 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000101140   ⟹   ENSRNOP00000085973
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,654,682 - 16,692,482 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000118155   ⟹   ENSRNOP00000089263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl616,654,614 - 16,692,045 (+)Ensembl
RefSeq Acc Id: NM_001414905   ⟹   NP_001401834
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,797 - 22,446,745 (+)NCBI
mRatBN7.2616,654,702 - 16,694,626 (+)NCBI
RefSeq Acc Id: NM_053600   ⟹   NP_446052
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,797 - 22,446,745 (+)NCBI
mRatBN7.2616,654,702 - 16,694,626 (+)NCBI
Rnor_6.06964,650 - 1,003,924 (-)NCBI
Rnor_5.06955,729 - 995,477 (-)NCBI
RGSC_v3.461,145,261 - 1,184,406 (-)RGD
Celera616,298,245 - 16,337,422 (+)RGD
Sequence:
RefSeq Acc Id: XM_006239639   ⟹   XP_006239701
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,698 - 22,435,733 (+)NCBI
mRatBN7.2616,654,601 - 16,674,060 (+)NCBI
Rnor_6.06983,462 - 1,003,955 (-)NCBI
Rnor_5.06955,729 - 995,477 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063262567   ⟹   XP_063118637
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,685 - 22,446,745 (+)NCBI
RefSeq Acc Id: XR_010052153
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8622,406,696 - 22,440,613 (+)NCBI
RefSeq Acc Id: NP_446052   ⟸   NM_053600
- Peptide Label: isoform 1
- UniProtKB: Q9JJ36 (UniProtKB/Swiss-Prot),   Q9JJ35 (UniProtKB/Swiss-Prot),   Q76LN1 (UniProtKB/Swiss-Prot),   P97578 (UniProtKB/Swiss-Prot),   A6H9W4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006239701   ⟸   XM_006239639
- Peptide Label: isoform X1
- UniProtKB: F7EYQ2 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000075253   ⟸   ENSRNOT00000082071
Ensembl Acc Id: ENSRNOP00000049923   ⟸   ENSRNOT00000042735
Ensembl Acc Id: ENSRNOP00000089263   ⟸   ENSRNOT00000118155
Ensembl Acc Id: ENSRNOP00000085973   ⟸   ENSRNOT00000101140
RefSeq Acc Id: NP_001401834   ⟸   NM_001414905
- Peptide Label: isoform 2
- UniProtKB: Q498V3 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063118637   ⟸   XM_063262567
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P97578-F1-model_v2 AlphaFold P97578 1-375 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13694359
Promoter ID:EPDNEW_R4875
Type:multiple initiation site
Name:Fez2_1
Description:fasciculation and elongation protein zeta 2
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.061,003,913 - 1,003,973EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:619709 AgrOrtholog
BioCyc Gene G2FUF-38483 BioCyc
Ensembl Genes ENSRNOG00000004577 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000042735.5 UniProtKB/TrEMBL
  ENSRNOT00000082071.2 UniProtKB/TrEMBL
  ENSRNOT00000101140.1 UniProtKB/TrEMBL
  ENSRNOT00000118155.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7128839 IMAGE-MGC_LOAD
InterPro FEZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:94269 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:112579 IMAGE-MGC_LOAD
NCBI Gene 94269 ENTREZGENE
PANTHER PTHR12394 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12394:SF11 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam FEZ UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Fez2 PhenoGen
RatGTEx ENSRNOG00000004577 RatGTEx
UniProt A0A0G2KA44_RAT UniProtKB/TrEMBL
  A0A8I6A3L1_RAT UniProtKB/TrEMBL
  A0A8I6A8A8_RAT UniProtKB/TrEMBL
  A6H9W3_RAT UniProtKB/TrEMBL
  A6H9W4 ENTREZGENE, UniProtKB/TrEMBL
  A6H9W5_RAT UniProtKB/TrEMBL
  F7EYQ2 ENTREZGENE, UniProtKB/TrEMBL
  FEZ2_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q498V3 ENTREZGENE, UniProtKB/TrEMBL
  Q76LH9_RAT UniProtKB/TrEMBL
  Q76LN1 ENTREZGENE
  Q9JJ35 ENTREZGENE
  Q9JJ36 ENTREZGENE
UniProt Secondary Q76LN1 UniProtKB/Swiss-Prot
  Q9JJ35 UniProtKB/Swiss-Prot
  Q9JJ36 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-01-20 Fez2  fasciculation and elongation protein zeta 2  Fez2  fasciculation and elongation protein zeta 2 (zygin II)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2013-04-17 Fez2  fasciculation and elongation protein zeta 2 (zygin II)  Zrp  zygin-related protein  Data merged from RGD:628711 737654 PROVISIONAL
2004-02-26 Fez2  fasciculation and elongation protein zeta 2 (zygin II)      Symbol and Name status set to approved 625702 APPROVED
2003-02-27 Zrp  zygin-related protein      Symbol and Name status set to provisional 70820 PROVISIONAL
2002-08-07 Fez2  fasciculation and elongation protein zeta 2 (zygin II)      Symbol and Name status set to provisional 70820 PROVISIONAL