Mir130b (microRNA 130b) - Rat Genome Database

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Gene: Mir130b (microRNA 130b) Rattus norvegicus
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Symbol: Mir130b
Name: microRNA 130b
RGD ID: 2325573
Description: Predicted to enable mRNA 3'-UTR binding activity and mRNA base-pairing post-transcriptional repressor activity. Predicted to be involved in several processes, including lipoprotein transport; miRNA-mediated gene silencing by mRNA destabilization; and negative regulation of cholesterol efflux. Predicted to act upstream of or within cellular response to leukemia inhibitory factor and sensory perception of sound. Orthologous to human MIR130B (microRNA 130b); INTERACTS WITH 2,5-hexanedione; 2-acetamidofluorene; aflatoxin B1.
Type: ncrna (Ensembl: miRNA)
RefSeq Status: PROVISIONAL
Previously known as: microRNA mir-130b; rno-mir-130b
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,384,380 - 97,384,461 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1197,384,380 - 97,384,461 (+)EnsemblGRCr8
mRatBN7.21183,880,163 - 83,880,244 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,880,163 - 83,880,244 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1192,603,886 - 92,603,967 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,265,028 - 85,265,109 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,318,609 - 84,318,690 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1199,242,315 - 99,242,396 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1197,444,764 - 97,444,845 (+)NCBILyon_Normotensive
Lyon_Hypertensive1198,362,969 - 98,363,050 (+)NCBILyon_Hypertensive
F344_StmMcwi1197,174,668 - 97,174,749 (+)NCBIF344_StmMcwi
Rnor_6.01188,129,773 - 88,129,854 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,129,773 - 88,129,854 (+)Ensemblrn6Rnor6.0
Rnor_5.01191,182,320 - 91,182,401 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1182,635,894 - 82,635,975 (+)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse:




Gene Ontology Annotations     Click to see Annotation Detail View

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:14691248   PMID:16381832   PMID:16766679   PMID:17604727   PMID:20403161   PMID:20439489   PMID:23646144   PMID:26255201   PMID:28412322   PMID:29995562   PMID:33300069   PMID:34080640  
PMID:35435532   PMID:37057740   PMID:37381993  


Genomics

Comparative Map Data
Mir130b
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81197,384,380 - 97,384,461 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1197,384,380 - 97,384,461 (+)EnsemblGRCr8
mRatBN7.21183,880,163 - 83,880,244 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1183,880,163 - 83,880,244 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1192,603,886 - 92,603,967 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01185,265,028 - 85,265,109 (+)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01184,318,609 - 84,318,690 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd1199,242,315 - 99,242,396 (+)NCBIDahl_SR_JrHsd
Lyon_Normotensive1197,444,764 - 97,444,845 (+)NCBILyon_Normotensive
Lyon_Hypertensive1198,362,969 - 98,363,050 (+)NCBILyon_Hypertensive
F344_StmMcwi1197,174,668 - 97,174,749 (+)NCBIF344_StmMcwi
Rnor_6.01188,129,773 - 88,129,854 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1188,129,773 - 88,129,854 (+)Ensemblrn6Rnor6.0
Rnor_5.01191,182,320 - 91,182,401 (+)NCBIRnor_5.0Rnor_5.0rn5
Celera1182,635,894 - 82,635,975 (+)NCBICelera
Cytogenetic Map11q23NCBI
MIR130B
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382221,653,304 - 21,653,385 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2221,653,304 - 21,653,385 (+)Ensemblhg38GRCh38
GRCh372222,007,593 - 22,007,674 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 362220,337,592 - 20,337,673 (+)NCBIBuild 36Build 36hg18NCBI36
Celera225,825,133 - 5,825,214 (+)NCBICelera
Cytogenetic Map22q11.21NCBI
HuRef224,965,417 - 4,965,498 (+)NCBIHuRef
CHM1_12222,007,785 - 22,007,866 (+)NCBICHM1_1
T2T-CHM13v2.02222,066,795 - 22,066,876 (+)NCBIT2T-CHM13v2.0
Mir130b
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391616,941,925 - 16,942,006 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1616,941,925 - 16,942,006 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381617,124,061 - 17,124,142 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1617,124,061 - 17,124,142 (-)Ensemblmm10GRCm38
MGSCv371617,124,154 - 17,124,235 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
Celera1617,696,855 - 17,696,936 (-)NCBICelera
Cytogenetic Map16A3NCBI
cM Map1610.61NCBI

miRNA Target Status (No longer updated)

Predicted Targets
Summary Value
Count of predictions:9927
Count of gene targets:6083
Count of transcripts:6563
Interacting mature miRNAs:rno-miR-130b-3p, rno-miR-130b-5p
Prediction methods:Microtar, Miranda, Pita, Pita,Targetscan, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)117385089499753367Rat
4889859Pur28Proteinuria QTL 2819.50.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)115892833699753367Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)116796218499753367Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)117330831599753367Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)116985594399753367Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)117961851999753367Rat


Expression

RNA-SEQ Expression

endocrine system
endoderm
hemolymphoid system
mesenchyme
mesoderm
renal system
reproductive system
respiratory system
1 1 1 5 1 4 2 1

Sequence


Ensembl Acc Id: ENSRNOT00000053664
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1197,384,380 - 97,384,461 (+)Ensembl
mRatBN7.2 Ensembl1183,880,163 - 83,880,244 (+)Ensembl
Rnor_6.0 Ensembl1188,129,773 - 88,129,854 (+)Ensembl
RefSeq Acc Id: NR_031877
RefSeq Status: PROVISIONAL
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81197,384,380 - 97,384,461 (+)NCBI
mRatBN7.21183,880,163 - 83,880,244 (+)NCBI
Dahl_SR_JrHsd1199,242,315 - 99,242,396 (+)NCBI
Lyon_Normotensive1197,444,764 - 97,444,845 (+)NCBI
Lyon_Hypertensive1198,362,969 - 98,363,050 (+)NCBI
F344_StmMcwi1197,174,668 - 97,174,749 (+)NCBI
Rnor_6.01188,129,773 - 88,129,854 (+)NCBI
Rnor_5.01191,182,320 - 91,182,401 (+)NCBI
Celera1182,635,894 - 82,635,975 (+)NCBI
Sequence:
Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:2325573 AgrOrtholog
BioCyc Gene G2FUF-20568 BioCyc
Ensembl Genes ENSRNOG00000035541 Ensembl, ENTREZGENE
Ensembl Transcript ENSRNOT00000053664 ENTREZGENE
miRBase MI0000904 ENTREZGENE
NCBI Gene 100314028 ENTREZGENE
PhenoGen Mir130b PhenoGen
RatGTEx ENSRNOG00000035541 RatGTEx
RNAcentral URS00002C0FCB RNACentral
  URS00003BD810 RNACentral
  URS000075B26D RNACentral


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-08-14 Mir130b  microRNA 130b  Mir130b  microRNA mir-130b  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2010-06-02 Mir130b  microRNA mir-130b      Symbol and Name status set to provisional 70820 PROVISIONAL