Advanced Search (OLGA)

Gene: Tmigd3 (transmembrane and immunoglobulin domain containing 3) Rattus norvegicus

Analyze

Symbol:

Tmigd3

Name:

transmembrane and immunoglobulin domain containing 3

RGD ID:

2324712

Description:

Predicted to enable transmembrane signaling receptor activity. Predicted to be involved in immune response-activating signaling pathway. Predicted to be active in plasma membrane. Orthologous to human TMIGD3 (transmembrane and immunoglobulin domain containing 3); INTERACTS WITH trichloroethene; leflunomide (ortholog).

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

Adora3 protein-like; LOC100363178

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Related Pseudogenes:

LOC100911347

Latest Assembly:

GRCr8 - GRCr8 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	196,027,286 - 196,103,430 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	196,027,286 - 196,103,428 (+)	Ensembl				GRCr8
mRatBN7.2	2	193,338,950 - 193,415,107 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	193,338,950 - 193,415,105 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	200,933,404 - 201,009,584 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	198,829,211 - 198,905,343 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	193,646,168 - 193,722,310 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	2	195,607,836 - 195,684,007 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	2	195,847,028 - 195,923,213 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	2	195,481,859 - 195,558,014 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	2	195,595,281 - 195,671,442 (+)	NCBI		F344_StmMcwi
Rnor_6.0	2	208,478,373 - 208,557,356 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	208,323,882 - 208,557,356 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	227,900,017 - 227,978,209 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	201,107,970 - 201,186,359 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	186,040,322 - 186,117,254 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autistic disorder (ISO)

COVID-19 (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

leflunomide (ISO)

trichloroethene (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of cell migration (ISO)

negative regulation of cell population proliferation (ISO)

Cellular Component

membrane (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:27886186

Genomics

Comparative Map Data

Tmigd3
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	2	196,027,286 - 196,103,430 (+)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	2	196,027,286 - 196,103,428 (+)	Ensembl				GRCr8
mRatBN7.2	2	193,338,950 - 193,415,107 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	2	193,338,950 - 193,415,105 (+)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	2	200,933,404 - 201,009,584 (+)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	2	198,829,211 - 198,905,343 (+)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	2	193,646,168 - 193,722,310 (+)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	2	195,607,836 - 195,684,007 (+)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	2	195,847,028 - 195,923,213 (+)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	2	195,481,859 - 195,558,014 (+)	NCBI		Lyon_Hypertensive
F344_StmMcwi	2	195,595,281 - 195,671,442 (+)	NCBI		F344_StmMcwi
Rnor_6.0	2	208,478,373 - 208,557,356 (+)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	2	208,323,882 - 208,557,356 (+)	Ensembl			rn6	Rnor6.0
Rnor_5.0	2	227,900,017 - 227,978,209 (+)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	2	201,107,970 - 201,186,359 (+)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	2	186,040,322 - 186,117,254 (+)	NCBI		Celera
Cytogenetic Map	2	q34	NCBI

TMIGD3
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	111,483,348 - 111,563,962 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	111,483,348 - 111,563,962 (-)	Ensembl			hg38	GRCh38
GRCh37	1	112,025,970 - 112,106,584 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Cytogenetic Map	1	p13.2	NCBI
CHM1_1	1	112,140,977 - 112,221,590 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	1	111,498,030 - 111,578,832 (-)	NCBI		T2T-CHM13v2.0

Tmigd3
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	3	105,778,174 - 105,831,360 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	3	105,811,799 - 105,826,108 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm39 Ensembl	3	105,778,174 - 105,816,242 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm39 Ensembl	3	105,778,219 - 105,831,358 (+)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	3	105,870,858 - 105,924,044 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	3	105,904,483 - 105,918,792 (+)	Ensembl			mm10	GRCm38
GRCm38.p6 Ensembl	3	105,870,858 - 105,908,926 (+)	Ensembl			mm10	GRCm38
GRCm38.p6 Ensembl	3	105,870,903 - 105,924,042 (+)	Ensembl			mm10	GRCm38
MGSCv36	3	105,998,963 - 106,052,092 (+)	NCBI		MGSCv36	mm8
Celera	3	108,059,748 - 108,112,934 (+)	NCBI		Celera
Cytogenetic Map	3	F2.2	NCBI

TMIGD3
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	17	63,904,582 - 63,907,044 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
Dog10K_Boxer_Tasha	17	63,418,171 - 63,420,460 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	17	65,076,072 - 65,078,361 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
UMICH_Zoey_3.1	17	63,811,019 - 63,813,306 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	17	63,869,840 - 63,872,128 (+)	NCBI		UNSW_CanFamBas_1.0

TMIGD3
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	4	108,854,357 - 108,873,925 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	4	108,814,405 - 108,871,101 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	4	118,996,431 - 119,053,021 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

Tmigd3
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	3	52,191,198 - 52,269,727 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in Tmigd3
544 total Variants

miRNA Target Status (No longer updated)

Predicted Target Of

	Summary Value
Count of predictions:	229
Count of miRNA genes:	162
Interacting mature miRNAs:	184
Transcripts:	ENSRNOT00000021288
Prediction methods:	Microtar, Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (GRCr8)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
1358356	Srcrt1	Stress Responsive Cort QTL1	3.66		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	2	163997722	225110681	Rat
1578648	Bss11	Bone structure and strength QTL 11	4.7		femur morphology trait (VT:0000559)	femoral neck cortical cross-sectional area (CMO:0001702)	2	169358774	214358774	Rat
1331734	Bp204	Blood pressure QTL 204	3.61192		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170656145	239614549	Rat
631566	Bp90	Blood pressure QTL 90		0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	149957381	221199885	Rat
1298074	Bp164	Blood pressure QTL 164		0.003	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
1354648	Bp239	Blood pressure QTL 239		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845370	229470703	Rat
1354649	Kidm17	Kidney mass QTL 17	2.9		kidney mass (VT:0002707)	calculated kidney weight (CMO:0000160)	2	83465462	229820014	Rat
1298076	Bp166	Blood pressure QTL 166		0.0009	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	138595962	205135428	Rat
10755499	Bp389	Blood pressure QTL 389	2.61		arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	20695736	231474293	Rat
1581576	Pur7	Proteinuria QTL 7		0.0001	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	80396178	220931218	Rat
61458	Bp10	Blood pressure QTL 10	3.42		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	191709311	217961898	Rat
1581578	Cm49	Cardiac mass QTL 49	4.9	0.01	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	145807215	220931416	Rat
152025245	Scl81	Serum cholesterol level QTL 81	3.49		blood cholesterol amount (VT:0000180)		2	124537199	209621565	Rat
631198	Cm22	Cardiac mass QTL 22	4.3	0.0008	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	78269809	208420281	Rat
1554319	Bmd2	Bone mineral density QTL 2	13.4	0.0001	lumbar vertebra area (VT:0010570)	lumbar vertebra cross-sectional area (CMO:0001689)	2	122597372	215234002	Rat
12879836	Kidm61	Kidney mass QTL 61		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	154723085	199723085	Rat
1581569	Uae32	Urinary albumin excretion QTL 32		0.0001	urine protein amount (VT:0005160)	urine albumin excretion rate (CMO:0000757)	2	80396178	220931218	Rat
12879837	Am2	Aortic mass QTL 2		0.001	aorta mass (VT:0002845)	aorta weight to aorta length to body weight ratio (CMO:0002722)	2	154723085	199723085	Rat
1302793	Bw16	Body weight QTL 16	5	0.0001	body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	205135267	Rat
12879838	Cm86	Cardiac mass QTL 86		0.002	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	2	154723085	199723085	Rat
12879839	Cm85	Cardiac mass QTL 85		0.001	heart mass (VT:0007028)	heart wet weight to body weight ratio (CMO:0002408)	2	154723085	199723085	Rat
1549833	Bp257	Blood pressure QTL 257		0.003	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	170652929	215652929	Rat
1358900	Bw48	Body weight QTL 48	4.88		body mass (VT:0001259)	body weight (CMO:0000012)	2	159440891	220931218	Rat
4889834	Pur24	Proteinuria QTL 24	5.8	0.014	urine total protein amount (VT:0000032)	urine total protein excretion rate (CMO:0000756)	2	171994826	205135428	Rat
1581499	Esta2	Estrogen-induced thymic atrophy QTL 2			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	2	192287802	229609668	Rat
1359031	Bp275	Blood pressure QTL 275			arterial blood pressure trait (VT:2000000)	diastolic blood pressure (CMO:0000005)	2	188565047	233565047	Rat
1331760	Bp206	Blood pressure QTL 206	3.62454		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	4265106	205135428	Rat
12879840	Bw179	Body weight QTL 179		0.005	body mass (VT:0001259)	body weight (CMO:0000012)	2	154723085	199723085	Rat
9589044	Scfw1	Subcutaneous fat weight QTL 1	5.8	0.001	subcutaneous adipose mass (VT:1000472)	abdominal subcutaneous fat pad weight (CMO:0002069)	2	184856304	229856304	Rat
8694435	Bw166	Body weight QTL 166	14.08	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	2	184856304	229856304	Rat
2301966	Bp322	Blood pressure QTL 322	3.58		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	144882354	205135428	Rat
1298083	Bp158	Blood pressure QTL 158	2.62		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	191709311	217961898	Rat
1298080	Bp163	Blood pressure QTL 163		0.02	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	67845182	205135428	Rat
1357991	Ael2	Aortic elastin QTL 2	4.2	0.000071	aorta elastin amount (VT:0003905)	aortic elastin	2	169227906	214227906	Rat
8662832	Vetf7	Vascular elastic tissue fragility QTL 7	3.5		aorta elastin amount (VT:0003905)	aorta wall extracellular elastin dry weight to aorta wall dry weight ratio (CMO:0002002)	2	83400752	223709938	Rat
1331745	Bp203	Blood pressure QTL 203	4.377		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	192287802	221089121	Rat
1298085	Bp165	Blood pressure QTL 165		0.0006	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	44537979	205135428	Rat
61366	Iddm3	Insulin dependent diabetes mellitus QTL 3	4.7		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	2	192287802	237287802	Rat
8694194	Abfw1	Abdominal fat weight QTL 1	11.7	0.001	visceral adipose mass (VT:0010063)	abdominal fat pad weight to body weight ratio (CMO:0000095)	2	184856304	229856304	Rat
1578671	Bmd10	Bone mineral density QTL 10	5.4		femur mineral mass (VT:0010011)	compact volumetric bone mineral density (CMO:0001730)	2	175931416	220931416	Rat
1641891	Alcrsp17	Alcohol response QTL 17			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	251712708	Rat
724534	Uae6	Urinary albumin excretion QTL 6	10		urine albumin amount (VT:0002871)	urine albumin level (CMO:0000130)	2	80396034	220931416	Rat
2300189	Bmd48	Bone mineral density QTL 48	5.8	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	2	182024327	227024327	Rat
61374	Edpm2	Estrogen-dependent pituitary mass QTL 2	4.42	0.86	pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	2	78269809	205135428	Rat
8662843	Vetf9	Vascular elastic tissue fragility QTL 9	2.05		thoracic aorta molecular composition trait (VT:0010568)	aorta wall extracellular elastin dry weight to aorta wall extracellular collagen weight ratio (CMO:0002003)	2	159440760	228950743	Rat
2301408	Kidm36	Kidney mass QTL 36		0.002	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	2	184482291	229482291	Rat
1331794	Bp202	Blood pressure QTL 202	3.66819		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	143344967	251712708	Rat
71113	Cari2	Carrageenan-induced inflammation QTL 2	2.7	0.009	hypodermis integrity trait (VT:0010550)	inflammatory exudate volume (CMO:0001429)	2	143746578	205135428	Rat
1331805	Cm29	Cardiac mass QTL 29	3.50746		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	2	143344967	251712708	Rat
634308	Sach6	Saccharin preference QTL 6	4.9		taste sensitivity trait (VT:0001986)	saccharin intake volume to total fluid intake volume ratio (CMO:0001601)	2	114384617	215381366	Rat
1358917	Cm42	Cardiac mass QTL 42	2.82		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
724568	Uae13	Urinary albumin excretion QTL 13	4.4		urine albumin amount (VT:0002871)	urine albumin excretion rate (CMO:0000757)	2	145306936	212705578	Rat
1358913	Cm41	Cardiac mass QTL 41	2.73		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	2	27148328	206613235	Rat
738013	Alc15	Alcohol consumption QTL 15	4.1	0.00022	consumption behavior trait (VT:0002069)	ethanol drink intake rate to body weight ratio (CMO:0001616)	2	186850607	231850607	Rat
1300165	Rf9	Renal function QTL 9	3.28		kidney glomerulus integrity trait (VT:0010546)	index of glomerular damage (CMO:0001135)	2	113746222	205135428	Rat
61398	Bp50	Blood pressure QTL 50	4.4		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	192287802	237287802	Rat
631507	Bp105	Blood pressure QTL 105		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	114384617	215381366	Rat
1641925	Alcrsp2	Alcohol response QTL 2			response to alcohol trait (VT:0010489)	duration of loss of righting reflex (CMO:0002289)	2	151869660	223841096	Rat
1354609	Niddm62	Non-insulin dependent diabetes mellitus QTL 62	4.72	0.000006	insulin secretion trait (VT:0003564)	plasma insulin level (CMO:0000342)	2	117415288	205135428	Rat
61417	Cia10	Collagen induced arthritis QTL 10	3.4		joint integrity trait (VT:0010548)	experimental arthritis severity measurement (CMO:0001459)	2	182635347	227635347	Rat
1354622	Kidm16	Kidney mass QTL 16	3		kidney mass (VT:0002707)	left kidney wet weight (CMO:0000083)	2	83465462	225110681	Rat
631266	Bp132	Blood pressure QTL 132		0.0005	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	47856345	205135428	Rat
631522	Bp74	Blood pressure QTL 74		0.05	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	175008837	220008837	Rat
8694383	Bw158	Body weight QTL 158	7.69	0.001	body lean mass (VT:0010483)	lean tissue morphological measurement (CMO:0002184)	2	184856304	229856304	Rat
7488927	Bp365	Blood pressure QTL 365		0.008	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	165453811	210453811	Rat
7488925	Bp364	Blood pressure QTL 364		0.001	arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	2	163253030	208253030	Rat
2306901	Bp337	Blood pressure QTL 337		0.01	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	2	166372086	229820014	Rat
1354605	Rf48	Renal function QTL 48	2.9		blood creatinine amount (VT:0005328)	plasma creatinine level (CMO:0000537)	2	76328396	209350714	Rat

Markers in Region

ADORA3

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	193,391,343 - 193,391,754 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	208,533,494 - 208,533,904	NCBI	Rnor6.0
Rnor_6.0	2	208,375,791 - 208,376,201	NCBI	Rnor6.0
Rnor_5.0	2	227,795,692 - 227,796,102	UniSTS	Rnor5.0
Rnor_5.0	2	227,954,972 - 227,955,382	UniSTS	Rnor5.0
RGSC_v3.4	2	201,160,413 - 201,160,823	UniSTS	RGSC3.4
Celera	2	186,092,710 - 186,093,120	UniSTS
Cytogenetic Map	2	q34	UniSTS

RH94668

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	2	193,392,060 - 193,392,199 (+)	MAPPER	mRatBN7.2
Rnor_6.0	2	208,534,211 - 208,534,349	NCBI	Rnor6.0
Rnor_6.0	2	208,376,508 - 208,376,646	NCBI	Rnor6.0
Rnor_5.0	2	227,955,689 - 227,955,827	UniSTS	Rnor5.0
Rnor_5.0	2	227,796,409 - 227,796,547	UniSTS	Rnor5.0
RGSC_v3.4	2	201,161,130 - 201,161,268	UniSTS	RGSC3.4
Celera	2	186,093,427 - 186,093,565	UniSTS
RH 3.4 Map	2	1369.2	UniSTS
Cytogenetic Map	2	q34	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	sensory system	visual system
11	1	13	59	26	22	10	48	10	6	116	75	3	53	19	48	12	10	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001302749	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590568	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590569	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017590570	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281090	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063281091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC097395	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473952	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FM077301	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000002	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000021288 ⟹ ENSRNOP00000021288

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	196,027,441 - 196,102,038 (+)	Ensembl
mRatBN7.2 Ensembl	2	193,338,950 - 193,410,796 (+)	Ensembl
Rnor_6.0 Ensembl	2	208,541,361 - 208,556,973 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000075939 ⟹ ENSRNOP00000068169

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	196,027,286 - 196,103,428 (+)	Ensembl
mRatBN7.2 Ensembl	2	193,338,950 - 193,415,105 (+)	Ensembl
Rnor_6.0 Ensembl	2	208,478,527 - 208,557,356 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000085178 ⟹ ENSRNOP00000072287

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	2	193,400,082 - 193,415,105 (+)	Ensembl
Rnor_6.0 Ensembl	2	208,323,882 - 208,557,354 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000133864 ⟹ ENSRNOP00000099143

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8 Ensembl	2	196,087,346 - 196,102,038 (+)	Ensembl

RefSeq Acc Id:

NM_001302749 ⟹ NP_001289678

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,027,286 - 196,103,430 (+)	NCBI
mRatBN7.2	2	193,338,950 - 193,415,107 (+)	NCBI
Dahl_SR_JrHsd	2	195,607,836 - 195,684,007 (+)	NCBI
Lyon_Normotensive	2	195,847,028 - 195,923,213 (+)	NCBI
Lyon_Hypertensive	2	195,481,859 - 195,558,014 (+)	NCBI
F344_StmMcwi	2	195,595,281 - 195,671,442 (+)	NCBI
Rnor_6.0	2	208,478,373 - 208,557,356 (+)	NCBI
Celera	2	186,040,322 - 186,117,254 (+)	NCBI

Sequence:

show sequence

TTACAGTTTCACAGCATCCAAATGGCTTGGAAAATCTGAGTGTGTCTGAGGCTCTGCTCTTACA
GTCAAGGCATGCCTGCCTGGTTCTCTAGAGAAGGGTTGGAGGGATGGAATGTGGCTGCTGCAAG
CTTCCATGGCAGTTGCTAAAGATGACCAGATGGACCTGCAGGACTTCAGCGGGACCCACTGACC
AAGAAGGGCAGATCCAGGGTTCCTGAGATCCTCCCTCGAGTTATTCCAGCTGAAGGCTCACTTC
CTTCTCAGCATGGAGCCCCTCCTACTGCTCTCCTTGGCTCTCTTTTCCGATGCCATGGTCATGG
ATGAAAAGGTGAAATCAGGCGTTGAGCTGGACACAGCTTCTGCAATCTGTAACTATGACGCCCA
CTACAAGGACCACACCAAGTACTGGTGCCGTGGCTATTTCAGGGACTCGTGCAACATTATTGCC
TTCACCCCTAATAGCAGCAACCGTGTGGCCCTGAAAGACACAGGAGACCAACTCATCATCACTG
TCTCCTGCCTGGTCAAGGAGGACACAGGCTGGTACTGGTGTGGTATCCAGCGGGACTTTGCCAG
AGATGACATGGATTTTACAAAGCTGATTGTGACTGACAACAGAGAAGACCGGGCCAATGGCCTT
TCACCTGGCACTTCAGGCAACAGGACCCGGAGCTGTAAGACGTCCAAAGCTGTTCAAAAGGCAG
AGGGCTCCCGAATGTCCATTCTGATCGTTTGTGTACTGATTAGCGGGCTGGGGATCATCTTTTT
AATCAGTCATATGTCCAGAGGAAGACGAAGCCAAAGAAACAGAGGAGTTACTGGCAAAAGCATC
AATAGAAACCCACAAGCAAGTCAAGCTCCGTCCATGGTCTCCATCCCCTTGACTGTCCTTCCCA
AGGTCCCAAGACAAAATGGTCAACAAAAAGCCCTCCAATGGACTGGAAATGCCACAAAGACCGG
ATAAGTGTATTCCTTTACTTGGGTTTGAAGGAATAGGGTGTAGAACTGGTCACTGGGGCTGCCG
TGGAGATTGTTCCTGCAGAGAACATGGAAGGTATCAGTTTTGGGGGGATCAGTATCTCTGCCCT
ACTCCTGCCGTCCCTCTCGGATAAGACCCTGAGCACGACCACTACCCACGGGAACTTGCAAGCC
GGCTACAACTCTTCAGAGGGAAGGGCAGTGAGTCTTTTCGCTGGTGCTGGGCAAGTGAACCCAG
GACTGTTTGCACACTGGGTCAAGCCCTCTACCACTGAGCTACATGCTATATCTCAGTGAGACCT
TTAAAATGAGAAGTAGAGCTGTACTTGAAAGGGTATACGAAATAAAGGAGCAGAGGTAGAGTGG
GAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XM_017590568 ⟹ XP_017446057

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,041,074 - 196,099,110 (+)	NCBI
mRatBN7.2	2	193,399,151 - 193,411,065 (+)	NCBI
Rnor_6.0	2	208,541,299 - 208,553,179 (+)	NCBI

Sequence:

show sequence

ATCCAGGGTTCCTGAGATCCTCCCTCGAGTTATTCCAGCTGAAGGCTCACTTCCTTCTCAGCAT
GGAGCCCCTCCTACTGCTCTCCTTGGCTCTCTTTTCCGATGCCATGGTCATGGATGAAAAGGTG
AAATCAGGCGTTGAGCTGGACACAGCTTCTGCAATCTGTAACTATGACGCCCACTACAAGGACC
ACACCAAGTACTGGTGCCGTGGCTATTTCAGGGACTCGTGCAACATTATTGCCTTCACCCCTAA
TAGCAGCAACCGTGTGGCCCTGAAAGACACAGGAGACCAACTCATCATCACTGTCTCCTGCCTG
GTCAAGGAGGACACAGGCTGGTACTGGTGTGGTATCCAGCGGGACTTTGCCAGAGATGACATGG
ATTTTACAAAGCTGATTGTGACTGACAACAGAGAAGACCGGGCCAATGGCCTTTCACCTGGCAC
TTCAGGCAACAGGACCCGGAGCTGTAAGACGTCCAAAGCTGTTCAAAAGGCAGAGGGCTCCCGA
ATGTCCATTCTGATCGTTTGTGTACTGATTAGCGGGCTGGGGATCATCTTTTTAATCAGTCATA
TGTCCAGAGGAAGACGAAGCCAAAGAAACAGAGGAGTTACTGGCAAAAGCATCAATAGAAACCC
ACAAGCAAGTCAAGCTCCGTCCATGGTCTCCATCCCCTTGGCAACGATTTGAAGTTCTTTCCAC
ATGTCCTGACTCAAGGAAATGGCTCAAGCAGAACGCGTGTGACTGAAGATTTATTTCATTTAGC
TCCTAAATAAAGTGATATCATTACAGTAGACTCTCCATGCCAACTGGTCTGCATCTCAGAGACT
GACTCTGACCTTTCAGGATTTCTAAAGGACTCTGTGACCTTGCAGCAATCTTTTATGGCCGATG
GCAACAGTGAGGCTCGGAAGATCTTTGGAGGAAGGCTGCCATT

hide sequence

RefSeq Acc Id:

XM_017590570 ⟹ XP_017446059

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,027,446 - 196,099,110 (+)	NCBI
mRatBN7.2	2	193,399,151 - 193,411,065 (+)	NCBI
Rnor_6.0	2	208,541,299 - 208,553,179 (+)	NCBI

Sequence:

show sequence

ATCCAGGGTTCCTGAGATCCTCCCTCGAGTTATTCCAGCTGAAGGCTCACTTCCTTCTCAGCAT
GGAGCCCCTCCTACTGCTCTCCTTGGCTCTCTTTTCCGATGCCATGGTCATGGATGAAAAGGTG
AAATCAGGCGTTGAGCTGGACACAGCTTCTGCAATCTGTAACTATGACGCCCACTACAAGGACC
ACACCAAGTACTGGTGCCGTGGCTATTTCAGGGACTCGTGCAACATTATTGCCTTCACCCCTAA
TAGCAGCAACCGTGTGGCCCTGAAAGACACAGGAGACCAACTCATCATCACTGTCTCCTGCCTG
GTCAAGGAGGACACAGGCTGGTACTGGTGTGGTATCCAGCGGGACTTTGCCAGAGATGACATGG
ATTTTACAAAGCTGATTGTGACTGACAACAGAGAAGACCGGGCCAATGGCCTTTCACCTGGCAC
TTCAGGCAACAGGACCCGGAGCTGTAAGACGTCCAAAGCTGTTCAAAAGGCAGAGGGCTCCCGA
ATGTCCATTCTGATCGTTTGTGTACTGATTAGCGGGCTGGGGATCATCTTTTTAATCAGTCATA
TGTCCAGAGGAAGACGAAGCCAAAGAAACAGAGGAGTTACTGGCAAAAGCATCAATAGAAACCC
ACAAGCAAGTCAAGCTCCGTCCATGGTCTCCATCCCCTTGTAGGCAACGATTTGAAGTTCTTTC
CACATGTCCTGACTCAAGGAAATGGCTCAAGCAGAACGCGTGTGACTGAAGATTTATTTCATTT
AGCTCCTAAATAAAGTGATATCATTACAGTAGACTCTCCATGCCAACTGGTCTGCATCTCAGAG
ACTGACTCTGACCTTTCAGGATTTCTAAAGGACTCTGTGACCTTGCAGCAATCTTTTATGGCCG
ATGGCAACAGTGAGGCTCGGAAGATCTTTGGAGGAAGGCTGCCATT

hide sequence

RefSeq Acc Id:

XM_063281089 ⟹ XP_063137159

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,027,446 - 196,099,110 (+)	NCBI

RefSeq Acc Id:

XM_063281090 ⟹ XP_063137160

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,027,473 - 196,099,110 (+)	NCBI

RefSeq Acc Id:

XM_063281091 ⟹ XP_063137161

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	2	196,075,804 - 196,099,110 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001289678	(Get FASTA)	NCBI Sequence Viewer
	XP_017446057	(Get FASTA)	NCBI Sequence Viewer
	XP_017446059	(Get FASTA)	NCBI Sequence Viewer
	XP_063137159	(Get FASTA)	NCBI Sequence Viewer
	XP_063137160	(Get FASTA)	NCBI Sequence Viewer
	XP_063137161	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH97395	(Get FASTA)	NCBI Sequence Viewer
	EDL81822	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000021288
	ENSRNOP00000021288.5
	ENSRNOP00000068169
	ENSRNOP00000068169.1
	ENSRNOP00000099143.1

RefSeq Acc Id:	NP_001289678 ⟸ NM_001302749
- Peptide Label:	precursor
- UniProtKB:	Q4V8H0 (UniProtKB/TrEMBL), F7FB47 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTP NSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPG TSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRN PQASQAPSMVSIPLTVLPKVPRQNGQQKALQWTGNATKTG hide sequence

RefSeq Acc Id:	XP_017446059 ⟸ XM_017590570
- Peptide Label:	isoform X2
- UniProtKB:	F7FB47 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTP NSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPG TSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRN PQASQAPSMVSIPL hide sequence

RefSeq Acc Id:	XP_017446057 ⟸ XM_017590568
- Peptide Label:	isoform X3
- UniProtKB:	A6HUN7 (UniProtKB/TrEMBL), F7FB47 (UniProtKB/TrEMBL)
- Sequence:	show sequence MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDHTKYWCRGYFRDSCNIIAFTP NSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDFARDDMDFTKLIVTDNREDRANGLSPG TSGNRTRSCKTSKAVQKAEGSRMSILIVCVLISGLGIIFLISHMSRGRRSQRNRGVTGKSINRN PQASQAPSMVSIPLATI hide sequence

Ensembl Acc Id:

ENSRNOP00000021288 ⟸ ENSRNOT00000021288

Ensembl Acc Id:

ENSRNOP00000072287 ⟸ ENSRNOT00000085178

Ensembl Acc Id:

ENSRNOP00000068169 ⟸ ENSRNOT00000075939

RefSeq Acc Id:	XP_063137159 ⟸ XM_063281089
- Peptide Label:	isoform X1
- UniProtKB:	F7FB47 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137160 ⟸ XM_063281090
- Peptide Label:	isoform X3
- UniProtKB:	A6HUN7 (UniProtKB/TrEMBL), F7FB47 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063137161 ⟸ XM_063281091
- Peptide Label:	isoform X3
- UniProtKB:	A6HUN7 (UniProtKB/TrEMBL), F7FB47 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000099143 ⟸ ENSRNOT00000133864

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q4V8H0-F1-model_v2	AlphaFold	Q4V8H0	1-232	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13691648

Promoter ID:

EPDNEW_R2171

Type:

initiation region

Name:

Tmigd3_1

Description:

transmembrane and immunoglobulin domain containing 3

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	2	208,478,511 - 208,478,571	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:2324712	AgrOrtholog
BioCyc Gene	G2FUF-51721	BioCyc
Ensembl Genes	ENSRNOG00000043375	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000021288	ENTREZGENE
	ENSRNOT00000021288.8	UniProtKB/TrEMBL
	ENSRNOT00000075939	ENTREZGENE
	ENSRNOT00000075939.4	UniProtKB/TrEMBL
	ENSRNOT00000133864.1	UniProtKB/TrEMBL
Gene3D-CATH	2.60.40.10	UniProtKB/TrEMBL
InterPro	CD300_family_receptors	UniProtKB/TrEMBL
	Ig-like_dom_sf	UniProtKB/TrEMBL
	Ig-like_fold	UniProtKB/TrEMBL
KEGG Report	rno:100363178	UniProtKB/TrEMBL
NCBI Gene	100363178	ENTREZGENE
PANTHER	POLYMERIC-IMMUNOGLOBULIN RECEPTOR	UniProtKB/TrEMBL
	TRANSMEMBRANE DOMAIN-CONTAINING PROTEIN TMIGD3	UniProtKB/TrEMBL
PhenoGen	Tmigd3	PhenoGen
RatGTEx	ENSRNOG00000043375	RatGTEx
Superfamily-SCOP	SSF48726	UniProtKB/TrEMBL
UniProt	A0ABK0KX07_RAT	UniProtKB/TrEMBL
	A6HUN7	ENTREZGENE, UniProtKB/TrEMBL
	F7FB47	ENTREZGENE, UniProtKB/TrEMBL
	Q4V8H0	ENTREZGENE, UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2016-06-09	Tmigd3	transmembrane and immunoglobulin domain containing 3	LOC100363178	Adora3 protein-like	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2010-05-12	LOC100363178	Adora3 protein-like			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Send us a Message

Imported Disease Annotations - ClinVar