Chchd2 (coiled-coil-helix-coiled-coil-helix domain containing 2) - Rat Genome Database

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Gene: Chchd2 (coiled-coil-helix-coiled-coil-helix domain containing 2) Heterocephalus glaber
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Symbol: Chchd2
Name: coiled-coil-helix-coiled-coil-helix domain containing 2
RGD ID: 18924077
Description: ENCODES a protein that exhibits DNA-binding transcription factor binding (ortholog); INVOLVED IN cellular response to oxidative stress (ortholog); positive regulation of mitochondrial ATP synthesis coupled electron transport (ortholog); regulation of cellular response to hypoxia (ortholog); ASSOCIATED WITH amelogenesis imperfecta (ortholog); Parkinson's disease 22 (ortholog); FOUND IN mitochondrial intermembrane space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: coiled-coil-helix-coiled-coil-helix domain-containing protein 2; coiled-coil-helix-coiled-coil-helix domain-containing protein 2, mitochondrial
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247408,278,078 - 8,283,657 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247408,279,416 - 8,283,730 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:30032202  


Genomics

Comparative Map Data
Chchd2
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247408,278,078 - 8,283,657 (-)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_0046247408,279,416 - 8,283,730 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
CHCHD2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38756,101,573 - 56,106,476 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl756,094,567 - 56,106,505 (-)Ensemblhg38GRCh38
GRCh37756,169,266 - 56,174,169 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36756,136,760 - 56,141,681 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34755,943,476 - 55,948,396NCBI
Celera767,222,175 - 67,227,096 (-)NCBICelera
Cytogenetic Map7p11.2NCBI
HuRef755,983,486 - 55,988,171 (-)NCBIHuRef
CHM1_1756,172,294 - 56,177,215 (-)NCBICHM1_1
T2T-CHM13v2.0756,261,388 - 56,266,291 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2756,173,513 - 56,178,434 (-)NCBI
Chchd2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395129,910,002 - 129,916,311 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5129,909,997 - 129,916,311 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm385129,881,161 - 129,887,470 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5129,881,156 - 129,887,470 (-)Ensemblmm10GRCm38
MGSCv375130,357,032 - 130,363,340 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv365130,165,865 - 130,172,173 (-)NCBIMGSCv36mm8
Celera5126,880,556 - 126,886,855 (-)NCBICelera
Cytogenetic Map5G1.3NCBI
cM Map568.26NCBI
Chchd2l3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr89101,947,769 - 101,948,440 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl9101,947,746 - 101,948,461 (-)EnsemblGRCr8
mRatBN7.2994,500,439 - 94,501,110 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl994,500,432 - 94,501,128 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx9102,935,898 - 102,936,569 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.09108,071,025 - 108,071,696 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.09106,427,988 - 106,428,659 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd9105,575,296 - 105,575,967 (-)NCBIDahl_SR_JrHsd
Lyon_Normotensive9101,425,237 - 101,425,908 (-)NCBILyon_Normotensive
Lyon_Hypertensive9101,550,385 - 101,551,056 (-)NCBILyon_Hypertensive
F344_StmMcwi9103,539,336 - 103,540,007 (-)NCBIF344_StmMcwi
Rnor_6.09101,388,148 - 101,388,819 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_5.09101,018,677 - 101,019,134 (-)NCBIRnor_5.0Rnor_5.0rn5
Rnor_5.09101,018,487 - 101,019,158 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4993,253,912 - 93,254,617 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
RGSC_v3.4927,858,760 - 28,053,369 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera992,034,380 - 92,035,051 (-)NCBICelera
RGSC_v3.1993,460,637 - 93,461,304 (-)NCBI
Cytogenetic Map9q36NCBI
Chchd2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554568,255,898 - 8,265,488 (-)Ensembl
ChiLan1.0NW_0049554568,260,533 - 8,265,488 (-)NCBIChiLan1.0ChiLan1.0
CHCHD2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2660,953,733 - 60,958,902 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan17109,278,455 - 109,283,547 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0756,714,583 - 56,719,640 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1757,136,723 - 57,141,765 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl757,134,303 - 57,141,765 (-)EnsemblpanPan2panpan1.1
CHCHD2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.16581,276 - 585,367 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl6581,280 - 585,301 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha62,280,745 - 2,284,839 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.06385,111 - 389,203 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl6385,115 - 389,137 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.16328,861 - 332,963 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.06322,956 - 327,041 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.06494,144 - 498,243 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Chchd2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344126,172,517 - 126,175,918 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365437,860,448 - 7,863,983 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365437,860,432 - 7,864,050 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CHCHD2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl316,812,404 - 16,819,124 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1316,812,409 - 16,819,130 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2317,065,147 - 17,071,876 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CHCHD2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1212,675,522 - 2,680,406 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041179,877,669 - 179,882,552 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Chchd2
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11624,130,126 - 24,136,056 (+)NCBIRrattus_CSIRO_v1


Expression

RNA-SEQ Expression


Sequence


Ensembl Acc Id: ENSHGLT00000022294   ⟹   ENSHGLP00000022083
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247408,278,078 - 8,283,657 (-)Ensembl
RefSeq Acc Id: XM_004839977   ⟹   XP_004840034
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247408,279,416 - 8,283,730 (-)NCBI
Protein Sequences
Protein RefSeqs XP_004840034 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSHGLP00000022083
GenBank Protein JAO03259 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: XP_004840034   ⟸   XM_004839977
- UniProtKB: A0A0P6JFV9 (UniProtKB/TrEMBL),   G5ASS6 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSHGLP00000022083   ⟸   ENSHGLT00000022294


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000015755 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000022294 ENTREZGENE
InterPro CHCH UniProtKB/TrEMBL
  CHCHD2/10-like UniProtKB/TrEMBL
KEGG Report hgl:101707417 UniProtKB/TrEMBL
NCBI Gene Chchd2 ENTREZGENE
PANTHER COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN CONTAINING 2/NUR77 UniProtKB/TrEMBL
  COILED-COIL-HELIX-COILED-COIL-HELIX DOMAIN-CONTAINING PROTEIN 2-RELATED UniProtKB/TrEMBL
Pfam CHCH UniProtKB/TrEMBL
PROSITE CHCH UniProtKB/TrEMBL
UniProt A0A0P6JFV9 ENTREZGENE, UniProtKB/TrEMBL
  G5ASS6 ENTREZGENE, UniProtKB/TrEMBL