Apbh (androgen-binding protein eta) - Rat Genome Database

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Gene: Apbh (androgen-binding protein eta) Rattus norvegicus
Analyze
Symbol: Apbh (Ensembl: Scgb1b24)
Name: androgen-binding protein eta (Ensembl:secretoglobin, family 1B, member 24)
RGD ID: 1596105
Description: Predicted to be located in extracellular region.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: Abpa2; androgen-binding protein eta-like; LOC689199; similar to androgen-binding protein eta
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8195,715,548 - 95,716,836 (+)NCBIGRCr8
mRatBN7.2186,588,137 - 86,589,425 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl186,588,137 - 86,589,425 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx191,994,399 - 91,995,687 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01100,460,572 - 100,461,860 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0193,752,702 - 93,753,990 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0189,785,552 - 89,786,842 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl189,785,552 - 89,954,289 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0190,936,251 - 90,937,541 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4186,401,001 - 86,402,289 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera180,948,517 - 80,949,805 (+)NCBICelera
Cytogenetic Map1q21NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
Additional References at PubMed
PMID:15256509   PMID:16018816   PMID:18269759  


Genomics

Variants

.
Variants in Apbh
30 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:33
Count of miRNA genes:33
Interacting mature miRNAs:33
Transcripts:ENSRNOT00000066292
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313059Bss55Bone structure and strength QTL 553.20.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
631688Hcas2Hepatocarcinoma susceptibility QTL 230.0001liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)15925874115540829Rat
1578649Bmd8Bone mineral density QTL 84.9femur mineral mass (VT:0010011)trabecular volumetric bone mineral density (CMO:0001729)14939317294393172Rat
1582234Gluco18Glucose level QTL 183.40.0003blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)178479925123479925Rat
1358359Sradr1Stress Responsive Adrenal Weight QTL 14.74adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)130882023123479925Rat
634314Niddm44Non-insulin dependent diabetes mellitus QTL 44blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)149393289199050459Rat
1578780Cm52Cardiac mass QTL 523.30.0001heart mass (VT:0007028)heart wet weight (CMO:0000069)181591954219808434Rat
1578654Bss10Bone structure and strength QTL 104femur morphology trait (VT:0000559)femoral neck cortical cross-sectional area (CMO:0001702)149393172159356837Rat
2300324Fetw1Fetal weight QTL 112.10.005fetal growth trait (VT:0004201)fetal body weight (CMO:0002080)185424647100358001Rat
2302059Pia36Pristane induced arthritis QTL 363.80.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G1 level (CMO:0002115)14333300288333002Rat
1300121Hrtrt1Heart rate QTL 13.7heart pumping trait (VT:2000009)heart rate (CMO:0000002)165789093115540829Rat
7421628Bp361Blood pressure QTL 3610.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)166023617118608521Rat
631495Bp96Blood pressure QTL 964.52arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)122340647102268831Rat
70225Bp58Blood pressure QTL 583.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132356093162846471Rat
631512Scl6Serum cholesterol level QTL 69.6blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)17219768090508767Rat
2298545Neuinf8Neuroinflammation QTL 84.6nervous system integrity trait (VT:0010566)spinal cord beta-2 microglobulin mRNA level (CMO:0002125)157336763151090257Rat
2313072Bss53Bone structure and strength QTL 534.30.0001tibia length (VT:0004357)tibia length (CMO:0000450)143284731118944897Rat
10059597Bp377Blood pressure QTL 3773.420.025arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)132737458199368955Rat
2313078Bss54Bone structure and strength QTL 543.50.0001tibia area (VT:1000281)tibia midshaft cross-sectional area (CMO:0001717)143284731118944897Rat
1549903Bp267Blood pressure QTL 267arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)177876254106047988Rat
2313083Bmd74Bone mineral density QTL 7440.0001tibia mineral mass (VT:1000283)total volumetric bone mineral density (CMO:0001728)182174743118944897Rat
2313402Anxrr24Anxiety related response QTL 24aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)148963584144267916Rat
4889494Scort2Serum corticosterone level QTL 24.2blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)180592172125592172Rat
61342Bp27Blood pressure QTL 273.40.0006arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)15673266898773277Rat
1300172Bp172Blood pressure QTL 1723.56arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)13273727390665040Rat
61344Bp29Blood pressure QTL 297.5arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)178350581123350581Rat
1358192Ept13Estrogen-induced pituitary tumorigenesis QTL 133.4pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)177494165122494165Rat
2313094Bss58Bone structure and strength QTL 583.70.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)143284731118944897Rat
6903308Scl36Serum cholesterol QTL 3620.0125blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)15386304190532583Rat
2300164Bmd44Bone mineral density QTL 445.40.0001lumbar vertebra mineral mass (VT:0010511)volumetric bone mineral density (CMO:0001553)156949932101949932Rat
2313099Bss56Bone structure and strength QTL 562.40.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)143284731118944897Rat
2313098Bmd70Bone mineral density QTL 703.60.0001tibia mineral mass (VT:1000283)compact volumetric bone mineral density (CMO:0001730)143284731118944897Rat
738022Anxrr13Anxiety related response QTL 134.60.00039locomotor behavior trait (VT:0001392)number of 20 x 20 cm floor squares crossed into, out of or within a discrete space in an experimental apparatus (CMO:0001514)183547917128547917Rat
152025249Scl82Serum cholesterol level QTL 824.77blood cholesterol amount (VT:0000180)15034351099980958Rat
10054135Gmadr2Adrenal mass QTL 21.970.0129adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)177857876122857876Rat
7411712Strs4Sensitivity to stroke QTL 48.7cerebrum integrity trait (VT:0010549)percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)178430536123430536Rat
2313051Bss57Bone structure and strength QTL 573.70.0001tibia strength trait (VT:1000284)bone polar moment of inertia (CMO:0001558)143284731118944897Rat
61433Cia2Collagen induced arthritis QTL 25joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)17843075491209302Rat


Expression

RNA-SEQ Expression

appendage
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
mesenchyme
mesoderm
nervous system
reproductive system
respiratory system
2 4 10 10 2 6 2 13 9 1 3 8

Sequence


Ensembl Acc Id: ENSRNOT00000110492   ⟹   ENSRNOP00000084754
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl186,588,137 - 86,589,425 (+)Ensembl
RefSeq Acc Id: NM_001170457   ⟹   NP_001163928
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8195,715,548 - 95,716,836 (+)NCBI
mRatBN7.2186,588,137 - 86,589,425 (+)NCBI
Rnor_6.0189,785,552 - 89,786,842 (+)NCBI
Rnor_5.0190,936,251 - 90,937,541 (+)NCBI
RGSC_v3.4186,401,001 - 86,402,289 (+)RGD
Celera180,948,517 - 80,949,805 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001163928 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ADB46073 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000084424.1
  ENSRNOP00000084754.1
RefSeq Acc Id: NP_001163928   ⟸   NM_001170457
- Peptide Label: precursor
- UniProtKB: D2XZ41 (UniProtKB/TrEMBL),   A6JA81 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000084754   ⟸   ENSRNOT00000110492

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
BioCyc Gene G2FUF-60031 BioCyc
Ensembl Genes ENSRNOG00000030828 Ensembl
  ENSRNOG00000064903 UniProtKB/TrEMBL
  ENSRNOG00000069356 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000110492.1 UniProtKB/TrEMBL
  ENSRNOT00000119884.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.920.50 UniProtKB/TrEMBL
InterPro Allergen_Fel_d_I_chain1 UniProtKB/TrEMBL
  Secretoglobin UniProtKB/TrEMBL
  Secretoglobin_Domain_sf UniProtKB/TrEMBL
  Secretoglobin_sf UniProtKB/TrEMBL
KEGG Report rno:292801 UniProtKB/TrEMBL
  rno:689199 UniProtKB/TrEMBL
NCBI Gene 689199 ENTREZGENE
PANTHER ABPA10-RELATED UniProtKB/TrEMBL
  PTHR21226 UniProtKB/TrEMBL
Pfam Uteroglobin UniProtKB/TrEMBL
PhenoGen Apbh PhenoGen
PRINTS FELALLERGEN UniProtKB/TrEMBL
PROSITE SCGB UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030828 RatGTEx
  ENSRNOG00000064903 RatGTEx
  ENSRNOG00000069356 RatGTEx
SMART UTG UniProtKB/TrEMBL
Superfamily-SCOP Secretoglobin UniProtKB/TrEMBL
UniProt A6JA81 ENTREZGENE, UniProtKB/TrEMBL
  D2XZ41 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-05-05 Apbh  androgen-binding protein eta  LOC689199  similar to androgen-binding protein eta  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-11-20 LOC689199  similar to androgen-binding protein eta      Symbol and Name status set to provisional 70820 PROVISIONAL