Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Muc15 | Rat | 17beta-estradiol | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in decreased expression of MUC15 mRNA | CTD | PMID:30165855 | Muc15 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MUC15 mRNA | CTD | PMID:32109520 and PMID:33387578 | Muc15 | Rat | Aroclor 1254 | decreases expression | ISO | Muc15 (Mus musculus) | 6480464 | Chlorodiphenyl (54% Chlorine) results in decreased expression of MUC15 mRNA | CTD | PMID:23650126 | Muc15 | Rat | arsane | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of MUC15 mRNA | CTD | PMID:32525701 | Muc15 | Rat | arsenic atom | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of MUC15 mRNA | CTD | PMID:32525701 | Muc15 | Rat | arsenite(3-) | affects methylation | ISO | MUC15 (Homo sapiens) | 6480464 | arsenite affects the methylation of MUC15 promoter | CTD | PMID:23974009 | Muc15 | Rat | avobenzone | decreases expression | ISO | MUC15 (Homo sapiens) | 6480464 | avobenzone results in decreased expression of MUC15 mRNA | CTD | PMID:31016361 | Muc15 | Rat | belinostat | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA | CTD | PMID:27188386 | Muc15 | Rat | belinostat | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | belinostat results in increased expression of MUC15 mRNA | CTD | PMID:26272509 | Muc15 | Rat | benzo[a]pyrene | decreases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of MUC15 mRNA | CTD | PMID:20106945 more ... | Muc15 | Rat | benzo[a]pyrene | affects methylation | ISO | MUC15 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MUC15 promoter | CTD | PMID:27901495 | Muc15 | Rat | benzo[a]pyrene | increases methylation | ISO | MUC15 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of MUC15 3' UTR | CTD | PMID:27901495 | Muc15 | Rat | benzo[a]pyrene | decreases methylation | ISO | MUC15 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of MUC15 exon | CTD | PMID:27901495 | Muc15 | Rat | bis(2-ethylhexyl) phthalate | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Diethylhexyl Phthalate results in increased expression of MUC15 mRNA | CTD | PMID:31163220 | Muc15 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of MUC15 mRNA | CTD | PMID:25181051 | Muc15 | Rat | bisphenol A | affects methylation | ISO | MUC15 (Homo sapiens) | 6480464 | bisphenol A affects the methylation of MUC15 gene | CTD | PMID:33391824 | Muc15 | Rat | CGP 52608 | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to MUC15 gene] | CTD | PMID:28238834 | Muc15 | Rat | chlorpyrifos | increases expression | ISO | Muc15 (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of MUC15 mRNA | CTD | PMID:37019170 | Muc15 | Rat | chromium(6+) | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [zinc chromate results in increased abundance of chromium hexavalent ion] which results in increased expression of MUC15 mRNA | CTD | PMID:38479592 | Muc15 | Rat | copper(II) sulfate | decreases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Copper Sulfate results in decreased expression of MUC15 mRNA | CTD | PMID:19549813 | Muc15 | Rat | cyclosporin A | decreases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of MUC15 mRNA | CTD | PMID:20106945 and PMID:25562108 | Muc15 | Rat | dorsomorphin | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Muc15 | Rat | mercury dibromide | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | mercuric bromide results in increased expression of MUC15 mRNA | CTD | PMID:26272509 | Muc15 | Rat | mercury dibromide | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA | CTD | PMID:27188386 | Muc15 | Rat | nickel atom | decreases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Nickel results in decreased expression of MUC15 mRNA | CTD | PMID:24768652 | Muc15 | Rat | p-chloromercuribenzoic acid | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | p-Chloromercuribenzoic Acid results in increased expression of MUC15 mRNA | CTD | PMID:26272509 | Muc15 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA | CTD | PMID:27188386 | Muc15 | Rat | panobinostat | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | panobinostat results in increased expression of MUC15 mRNA | CTD | PMID:26272509 | Muc15 | Rat | panobinostat | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA | CTD | PMID:27188386 | Muc15 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of MUC15 mRNA | CTD | PMID:33387578 | Muc15 | Rat | phenylmercury acetate | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in increased expression of MUC15 mRNA | CTD | PMID:26272509 | Muc15 | Rat | phenylmercury acetate | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA | CTD | PMID:27188386 | Muc15 | Rat | quercetin | decreases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Quercetin results in decreased expression of MUC15 mRNA | CTD | PMID:21632981 | Muc15 | Rat | SB 431542 | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Muc15 | Rat | sodium arsenate | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of MUC15 mRNA | CTD | PMID:32525701 | Muc15 | Rat | sodium arsenite | decreases expression | ISO | Muc15 (Mus musculus) | 6480464 | sodium arsenite results in decreased expression of MUC15 mRNA | CTD | PMID:36209798 and PMID:37682722 | Muc15 | Rat | sodium dodecyl sulfate | decreases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Sodium Dodecyl Sulfate results in decreased expression of MUC15 mRNA | CTD | PMID:31734321 | Muc15 | Rat | trichloroethene | decreases methylation | EXP | | 6480464 | Trichloroethylene results in decreased methylation of MUC15 gene | CTD | PMID:27618143 | Muc15 | Rat | trichloroethene | decreases expression | EXP | | 6480464 | Trichloroethylene results in decreased expression of MUC15 mRNA | CTD | PMID:33387578 | Muc15 | Rat | trichostatin A | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | trichostatin A results in increased expression of MUC15 mRNA | CTD | PMID:24935251 and PMID:26272509 | Muc15 | Rat | trichostatin A | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA | CTD | PMID:27188386 | Muc15 | Rat | troglitazone | increases expression | EXP | | 6480464 | troglitazone results in increased expression of MUC15 mRNA | CTD | PMID:21515302 | Muc15 | Rat | valproic acid | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of MUC15 mRNA | CTD | PMID:23179753 more ... | Muc15 | Rat | valproic acid | decreases expression | ISO | MUC15 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MUC15 mRNA | CTD | PMID:28001369 | Muc15 | Rat | valproic acid | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA | CTD | PMID:27188386 | Muc15 | Rat | vorinostat | multiple interactions | ISO | MUC15 (Homo sapiens) | 6480464 | [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of MUC15 mRNA | CTD | PMID:27188386 | Muc15 | Rat | vorinostat | increases expression | ISO | MUC15 (Homo sapiens) | 6480464 | vorinostat results in increased expression of MUC15 mRNA | CTD | PMID:26272509 | |