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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1589864
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Muc15
Name: mucin 15, cell surface associated
Acc ID: CHEBI:29865
Term: benzo[a]pyrene
Definition: An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.
Chemical ID: MESH:D001564
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Muc15affects methylationISOMUC15 (Homo sapiens)6480464CTDBenzo(a)pyrene affects the methylation of MUC15 promoterPMID:27901495
Muc15decreases expressionISOMUC15 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased expression of MUC15 mRNAPMID:20106945 PMID:21632981 PMID:32234424
Muc15decreases methylationISOMUC15 (Homo sapiens)6480464CTDBenzo(a)pyrene results in decreased methylation of MUC15 exonPMID:27901495
Muc15increases methylationISOMUC15 (Homo sapiens)6480464CTDBenzo(a)pyrene results in increased methylation of MUC15 3' UTRPMID:27901495
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