Dcaf6 (DDB1 and CUL4 associated factor 6) - Rat Genome Database

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Pathways
Gene: Dcaf6 (DDB1 and CUL4 associated factor 6) Rattus norvegicus
Analyze
Symbol: Dcaf6
Name: DDB1 and CUL4 associated factor 6
RGD ID: 1561961
Description: Predicted to enable transcription coactivator activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of Cul4-RING E3 ubiquitin ligase complex. Predicted to be active in cytoplasm. Orthologous to human DCAF6 (DDB1 and CUL4 associated factor 6); INTERACTS WITH 1,3-dinitrobenzene; 2,2',4,4'-Tetrabromodiphenyl ether; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: DDB1- and CUL4-associated factor 6; IQ motif and WD repeats 1; Iqwd1; LOC289181; RGD1561961; similar to IQ motif and WD repeats 1
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81380,159,282 - 80,260,510 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1380,159,321 - 80,260,510 (-)EnsemblGRCr8
mRatBN7.21377,626,257 - 77,727,645 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1377,626,307 - 77,727,512 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1380,239,714 - 80,340,887 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01381,543,721 - 81,644,886 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01378,789,777 - 78,890,985 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01383,578,730 - 83,680,330 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1383,579,036 - 83,680,207 (-)Ensemblrn6Rnor6.0
Rnor_5.01388,458,188 - 88,559,884 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41381,082,713 - 81,183,953 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1377,339,691 - 77,440,873 (-)NCBICelera
Cytogenetic Map13q23NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
Cul4-RING E3 ubiquitin ligase complex  (IBA,IEA,ISO)
cytoplasm  (IBA)
nucleoplasm  (IEA,ISO)
nucleus  (IEA,ISO)

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:15784617   PMID:16949367  


Genomics

Comparative Map Data
Dcaf6
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81380,159,282 - 80,260,510 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl1380,159,321 - 80,260,510 (-)EnsemblGRCr8
mRatBN7.21377,626,257 - 77,727,645 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1377,626,307 - 77,727,512 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx1380,239,714 - 80,340,887 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01381,543,721 - 81,644,886 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01378,789,777 - 78,890,985 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.01383,578,730 - 83,680,330 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1383,579,036 - 83,680,207 (-)Ensemblrn6Rnor6.0
Rnor_5.01388,458,188 - 88,559,884 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.41381,082,713 - 81,183,953 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera1377,339,691 - 77,440,873 (-)NCBICelera
Cytogenetic Map13q23NCBI
DCAF6
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381167,863,576 - 168,075,836 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1167,935,783 - 168,076,223 (+)Ensemblhg38GRCh38
GRCh371167,905,477 - 168,045,074 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361166,172,532 - 166,311,705 (+)NCBIBuild 36Build 36hg18NCBI36
Build 341164,675,829 - 164,776,731NCBI
Celera1141,015,162 - 141,154,064 (+)NCBICelera
Cytogenetic Map1q24.2NCBI
HuRef1139,151,436 - 139,289,686 (+)NCBIHuRef
CHM1_11169,328,001 - 169,467,291 (+)NCBICHM1_1
T2T-CHM13v2.01167,215,301 - 167,427,301 (+)NCBIT2T-CHM13v2.0
Dcaf6
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391165,157,069 - 165,288,475 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1165,156,267 - 165,288,044 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm381165,329,500 - 165,460,906 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1165,328,698 - 165,460,475 (-)Ensemblmm10GRCm38
MGSCv371167,259,631 - 167,390,594 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv361167,166,614 - 167,296,902 (-)NCBIMGSCv36mm8
Celera1167,774,094 - 167,906,593 (-)NCBICelera
Cytogenetic Map1H2.2- H2.3NCBI
cM Map172.67NCBI
Dcaf6
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554629,037,118 - 9,176,713 (-)Ensembl
ChiLan1.0NW_0049554629,036,710 - 9,176,981 (-)NCBIChiLan1.0ChiLan1.0
DCAF6
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2181,689,221 - 81,827,638 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1181,357,896 - 81,495,634 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01143,424,700 - 143,563,049 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11147,151,691 - 147,289,629 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1147,162,680 - 147,289,629 (+)EnsemblpanPan2panpan1.1
DCAF6
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1730,413,441 - 30,544,421 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl730,413,553 - 30,544,260 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha729,950,559 - 30,081,621 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0730,231,666 - 30,362,838 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl730,231,671 - 30,362,811 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1730,071,551 - 30,202,616 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0730,102,565 - 30,233,681 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0730,340,586 - 30,471,915 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Dcaf6
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024409344100,286,354 - 100,381,373 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648118,133,497 - 18,228,120 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_00493648118,133,115 - 18,228,122 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
DCAF6
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl482,911,577 - 83,069,699 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1482,911,576 - 83,069,718 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2490,584,900 - 90,745,353 (-)NCBISscrofa10.2Sscrofa10.2susScr3
DCAF6
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12560,968,836 - 61,109,235 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2560,967,870 - 61,109,562 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366605562,694,055 - 62,835,005 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Dcaf6
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248265,937,322 - 6,082,539 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Dcaf6
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v11044,474,390 - 44,575,156 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Dcaf6
621 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:171
Count of miRNA genes:133
Interacting mature miRNAs:148
Transcripts:ENSRNOT00000004199
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1298066Bp159Blood pressure QTL 1590.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)134863963493639634Rat
10755495Bp387Blood pressure QTL 3873.78arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133721624190057603Rat
1354655Bp241Blood pressure QTL 2413.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)1338975045103588154Rat
8655951Rf63Renal function QTL 6312.2blood urea nitrogen amount (VT:0005265)plasma urea nitrogen level (CMO:0000586)1371610804109350286Rat
70220Bp55Blood pressure QTL 555.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
8655945Rf61Renal function QTL 613.6blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)137161080489333251Rat
71119Thym2Thymus enlargement QTL 23.8thymus mass (VT:0004954)thymus weight to body weight ratio (CMO:0000612)134874981487285480Rat
4889861Pur29Proteinuria QTL 2913.80.005urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)133996821183286298Rat
1331783Bp221Blood pressure QTL 2213.72886arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)137161080489333251Rat
8655959Pur32Proteinuria QTL 328.4urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)137298450699745408Rat
2293687Bss26Bone structure and strength QTL 264.60.0001femur morphology trait (VT:0000559)femur cross-sectional area (CMO:0001661)1367635937109350286Rat
1300166Kidm6Kidney mass QTL 63.93kidney mass (VT:0002707)single kidney wet weight to body weight ratio (CMO:0000622)137161080489333251Rat
619615Bp80Blood pressure QTL 800.0354arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)13742179187286911Rat
61340Bp25Blood pressure QTL 254.20.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)133708798382087983Rat
1581573Uae36Urinary albumin excretion QTL 36urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
1549897Stresp12Stress response QTL 123.35stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)134098358585983585Rat
724564Uae11Urinary albumin excretion QTL 115.7urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)134735425894285672Rat
7207885Glom27Glomerulus QTL 273.9kidney glomerulus integrity trait (VT:0010546)kidney crescentic glomeruli count to kidney normal glomeruli count ratio (CMO:0002139)1321120177109350286Rat
738027Lnnr6Liver neoplastic nodule remodeling QTL 63.3liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)1365613454109350286Rat
7387280Uae43Urinary albumin excretion QTL 435.690.4174urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)1368983334109350286Rat
738026Lnnr5Liver neoplastic nodule remodeling QTL 53.29liver integrity trait (VT:0010547)liver remodeling tumorous lesion number (CMO:0001461)136242459288113509Rat
2293702Bss34Bone structure and strength QTL 344.610.0001femur strength trait (VT:0010010)femur midshaft polar moment of inertia (CMO:0001669)1367635937109350286Rat
61349Bp31Blood pressure QTL 315.75arterial blood pressure trait (VT:2000000)blood pressure measurement (CMO:0000003)133992469384924693Rat
1576318Schws5Schwannoma susceptibility QTL 50.0351nervous system integrity trait (VT:0010566)post-insult time to trigeminal nerve neurilemmoma formation (CMO:0002019)1364497900109350286Rat
1354621Rf47Renal function QTL 473.7kidney renin amount (VT:0010559)kidney renin level (CMO:0002166)1311081740103588154Rat
1581554Pur11Proteinuria QTL 11urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)13600200888706694Rat
12879477Bp401Blood pressure QTL 401arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)133981472684814726Rat
1331750Bp220Blood pressure QTL 2202.98arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)133996821184968211Rat
12879475Bp400Blood pressure QTL 400arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)1364375743109350286Rat
11530006Niddm72Non-insulin dependent diabetes mellitus QTL 720.001blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)133828629883286298Rat
1354666Bp244Blood pressure QTL 2444.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)131103588154Rat
2293341Glom15Glomerulus QTL 159.1kidney glomerulus integrity trait (VT:0010546)kidney sclerotic glomeruli count to total glomeruli count ratio (CMO:0001269)1367635937109350286Rat

Markers in Region
D13Got61  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21377,697,642 - 77,697,877 (+)MAPPERmRatBN7.2
Rnor_6.01383,650,471 - 83,650,705NCBIRnor6.0
Rnor_5.01388,529,929 - 88,530,163UniSTSRnor5.0
RGSC_v3.41381,153,993 - 81,154,227UniSTSRGSC3.4
RGSC_v3.41381,153,992 - 81,154,227RGDRGSC3.4
Celera1377,411,081 - 77,411,315UniSTS
RGSC_v3.11381,168,181 - 81,168,415RGD
RH 3.4 Map13481.1UniSTS
RH 3.4 Map13481.1RGD
RH 2.0 Map13570.8RGD
Cytogenetic Map13q23UniSTS
D13Got252  
Rat AssemblyChrPosition (strand)SourceJBrowse
GRCr81380,195,902 - 80,196,087 (+)Marker Load Pipeline
mRatBN7.21377,662,892 - 77,663,077 (+)MAPPERmRatBN7.2
Rnor_6.01383,615,646 - 83,615,830NCBIRnor6.0
Rnor_5.01388,495,104 - 88,495,288UniSTSRnor5.0
RGSC_v3.41381,118,940 - 81,119,124UniSTSRGSC3.4
Celera1377,376,133 - 77,376,320UniSTS
Cytogenetic Map13q23UniSTS
BM391802  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21377,664,151 - 77,664,358 (+)MAPPERmRatBN7.2
Rnor_6.01383,616,905 - 83,617,111NCBIRnor6.0
Rnor_5.01388,496,363 - 88,496,569UniSTSRnor5.0
RGSC_v3.41381,120,199 - 81,120,405UniSTSRGSC3.4
Celera1377,377,395 - 77,377,601UniSTS
RH 3.4 Map13479.7UniSTS
Cytogenetic Map13q23UniSTS
RH138015  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21377,707,125 - 77,707,253 (+)MAPPERmRatBN7.2
Rnor_6.01383,659,954 - 83,660,081NCBIRnor6.0
Rnor_5.01388,539,412 - 88,539,539UniSTSRnor5.0
RGSC_v3.41381,163,475 - 81,163,602UniSTSRGSC3.4
Celera1377,420,497 - 77,420,624UniSTS
RH 3.4 Map13481.1UniSTS
Cytogenetic Map13q23UniSTS
RH139030  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21377,727,661 - 77,727,801 (+)MAPPERmRatBN7.2
Rnor_6.01383,680,488 - 83,680,627NCBIRnor6.0
Rnor_5.01388,559,946 - 88,560,085UniSTSRnor5.0
RGSC_v3.41381,184,010 - 81,184,149UniSTSRGSC3.4
Celera1377,441,031 - 77,441,170UniSTS
RH 3.4 Map13479.8UniSTS
Cytogenetic Map13q23UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 163 91 90 59 92 59 6 356 192 11 142 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001305159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250196 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250197 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250198 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250199 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250201 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039090500 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063272121 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_213926 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH473958 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000013 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000004199   ⟹   ENSRNOP00000004199
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1380,159,321 - 80,260,510 (-)Ensembl
mRatBN7.2 Ensembl1377,626,454 - 77,727,512 (-)Ensembl
Rnor_6.0 Ensembl1383,579,036 - 83,680,207 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000099982   ⟹   ENSRNOP00000076918
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1380,159,321 - 80,260,510 (-)Ensembl
mRatBN7.2 Ensembl1377,626,454 - 77,727,512 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000106410   ⟹   ENSRNOP00000080747
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1380,163,431 - 80,260,510 (-)Ensembl
mRatBN7.2 Ensembl1377,630,419 - 77,727,512 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000117589   ⟹   ENSRNOP00000081342
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1380,159,321 - 80,260,510 (-)Ensembl
mRatBN7.2 Ensembl1377,626,307 - 77,727,504 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000159488   ⟹   ENSRNOP00000105578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl1380,159,321 - 80,260,510 (-)Ensembl
RefSeq Acc Id: NM_001305159   ⟹   NP_001292088
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,321 - 80,260,510 (-)NCBI
mRatBN7.21377,626,307 - 77,727,504 (-)NCBI
Rnor_6.01383,578,769 - 83,680,330 (-)NCBI
Celera1377,339,691 - 77,440,873 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250194   ⟹   XP_006250256
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
mRatBN7.21377,626,257 - 77,727,637 (-)NCBI
Rnor_6.01383,578,730 - 83,680,178 (-)NCBI
Rnor_5.01388,458,188 - 88,559,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250195   ⟹   XP_006250257
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
mRatBN7.21377,626,257 - 77,727,639 (-)NCBI
Rnor_6.01383,578,730 - 83,680,178 (-)NCBI
Rnor_5.01388,458,188 - 88,559,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250196   ⟹   XP_006250258
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
mRatBN7.21377,626,257 - 77,727,638 (-)NCBI
Rnor_6.01383,578,730 - 83,680,178 (-)NCBI
Rnor_5.01388,458,188 - 88,559,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250197   ⟹   XP_006250259
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
mRatBN7.21377,626,257 - 77,727,637 (-)NCBI
Rnor_6.01383,578,730 - 83,680,178 (-)NCBI
Rnor_5.01388,458,188 - 88,559,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250198   ⟹   XP_006250260
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
mRatBN7.21377,626,257 - 77,727,638 (-)NCBI
Rnor_6.01383,578,730 - 83,680,178 (-)NCBI
Rnor_5.01388,458,188 - 88,559,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250199   ⟹   XP_006250261
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
mRatBN7.21377,626,257 - 77,727,637 (-)NCBI
Rnor_6.01383,578,730 - 83,680,178 (-)NCBI
Rnor_5.01388,458,188 - 88,559,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006250201   ⟹   XP_006250263
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
mRatBN7.21377,626,257 - 77,727,635 (-)NCBI
Rnor_6.01383,578,730 - 83,680,178 (-)NCBI
Rnor_5.01388,458,188 - 88,559,884 (-)NCBI
Sequence:
RefSeq Acc Id: XM_039090500   ⟹   XP_038946428
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,168,918 - 80,260,343 (-)NCBI
mRatBN7.21377,635,906 - 77,727,645 (-)NCBI
RefSeq Acc Id: XM_063272118   ⟹   XP_063128188
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
RefSeq Acc Id: XM_063272119   ⟹   XP_063128189
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,325 (-)NCBI
RefSeq Acc Id: XM_063272120   ⟹   XP_063128190
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
RefSeq Acc Id: XM_063272121   ⟹   XP_063128191
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
RefSeq Acc Id: XM_213926   ⟹   XP_213926
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr81380,159,282 - 80,260,343 (-)NCBI
mRatBN7.21377,626,257 - 77,727,639 (-)NCBI
Rnor_6.01383,578,730 - 83,680,178 (-)NCBI
Rnor_5.01388,458,188 - 88,559,884 (-)NCBI
RGSC_v3.41381,082,713 - 81,183,953 (-)RGD
Sequence:
RefSeq Acc Id: XP_213926   ⟸   XM_213926
- Peptide Label: isoform X1
- UniProtKB: D4A8L4 (UniProtKB/TrEMBL),   A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250261   ⟸   XM_006250199
- Peptide Label: isoform X12
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250260   ⟸   XM_006250198
- Peptide Label: isoform X9
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250259   ⟸   XM_006250197
- Peptide Label: isoform X7
- UniProtKB: A0A8I5ZSR3 (UniProtKB/TrEMBL),   A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250263   ⟸   XM_006250201
- Peptide Label: isoform X6
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250258   ⟸   XM_006250196
- Peptide Label: isoform X5
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250257   ⟸   XM_006250195
- Peptide Label: isoform X3
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250256   ⟸   XM_006250194
- Peptide Label: isoform X2
- UniProtKB: A0A8I5Y6I7 (UniProtKB/TrEMBL),   A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001292088   ⟸   NM_001305159
- UniProtKB: A6IDG8 (UniProtKB/TrEMBL),   A0A8I5ZQH9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000004199   ⟸   ENSRNOT00000004199
RefSeq Acc Id: XP_038946428   ⟸   XM_039090500
- Peptide Label: isoform X8
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000076918   ⟸   ENSRNOT00000099982
Ensembl Acc Id: ENSRNOP00000081342   ⟸   ENSRNOT00000117589
Ensembl Acc Id: ENSRNOP00000080747   ⟸   ENSRNOT00000106410
RefSeq Acc Id: XP_063128191   ⟸   XM_063272121
- Peptide Label: isoform X13
RefSeq Acc Id: XP_063128190   ⟸   XM_063272120
- Peptide Label: isoform X11
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128188   ⟸   XM_063272118
- Peptide Label: isoform X4
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063128189   ⟸   XM_063272119
- Peptide Label: isoform X10
- UniProtKB: A0A8I5ZQH9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000105578   ⟸   ENSRNOT00000159488

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4A8L4-F1-model_v2 AlphaFold D4A8L4 1-943 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561961 AgrOrtholog
BioCyc Gene G2FUF-17569 BioCyc
Ensembl Genes ENSRNOG00000003078 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000004199 ENTREZGENE
  ENSRNOT00000004199.9 UniProtKB/TrEMBL
  ENSRNOT00000099982 ENTREZGENE
  ENSRNOT00000099982.2 UniProtKB/TrEMBL
  ENSRNOT00000106410.2 UniProtKB/TrEMBL
  ENSRNOT00000117589 ENTREZGENE
  ENSRNOT00000117589.2 UniProtKB/TrEMBL
  ENSRNOT00000159488 ENTREZGENE
  ENSRNOT00000159488.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
InterPro DCAF8 UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:289181 UniProtKB/TrEMBL
NCBI Gene 289181 ENTREZGENE
PANTHER DDB1- AND CUL4-ASSOCIATED FACTOR 6 UniProtKB/TrEMBL
  PTHR15574 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Dcaf6 PhenoGen
PROSITE PS50096 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000003078 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A8I5Y6I7 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZQH9 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I5ZSR3 ENTREZGENE, UniProtKB/TrEMBL
  A0ABK0LTQ7_RAT UniProtKB/TrEMBL
  A6IDG8 ENTREZGENE, UniProtKB/TrEMBL
  D4A8L4 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2009-10-22 Dcaf6  DDB1 and CUL4 associated factor 6  Iqwd1  IQ motif and WD repeats 1  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-02-29 Iqwd1  IQ motif and WD repeats 1  RGD1561961_predicted  similar to IQ motif and WD repeats 1 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1561961_predicted  similar to IQ motif and WD repeats 1 (predicted)  LOC289181  similar to IQ motif and WD repeats 1  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC289181  similar to IQ motif and WD repeats 1      Symbol and Name status set to provisional 70820 PROVISIONAL