Eif2s3 (eukaryotic translation initiation factor 2 subunit gamma) - Rat Genome Database

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Gene: Eif2s3 (eukaryotic translation initiation factor 2 subunit gamma) Rattus norvegicus
Analyze
Symbol: Eif2s3
Name: eukaryotic translation initiation factor 2 subunit gamma
RGD ID: 1561279
Description: Predicted to enable methionyl-initiator methionine tRNA binding activity; translation factor activity, RNA binding; and translation initiation factor activity. Predicted to contribute to tRNA binding activity. Predicted to be involved in formation of translation preinitiation complex. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 2 complex. Predicted to be active in synapse. Human ortholog(s) of this gene implicated in MEHMO syndrome. Orthologous to several human genes including EIF2S3 (eukaryotic translation initiation factor 2 subunit gamma); PARTICIPATES IN translation initiation pathway; INTERACTS WITH 2,4-dinitrotoluene; 2,6-dinitrotoluene; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: eIF-2-gamma; eIF-2-gamma X; eIF2-gamma; eIF2-gamma X; Eif2g; Eif2s3x; Eukaryotic translation initiation factor 2 subunit 3; eukaryotic translation initiation factor 2 subunit 3, X-linked; eukaryotic translation initiation factor 2 subunit gamma, X-linked; eukaryotic translation initiation factor 2, subunit 3 gamma; eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked; PP42
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X62,910,292 - 62,933,936 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX62,910,293 - 62,934,489 (-)EnsemblGRCr8
mRatBN7.2X58,916,513 - 58,939,923 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX58,917,490 - 58,940,686 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX60,355,258 - 60,378,612 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X63,856,376 - 63,879,732 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X61,407,452 - 61,430,813 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X63,268,106 - 63,291,125 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX63,268,037 - 63,292,092 (-)Ensemblrn6Rnor6.0
Rnor_5.0X63,861,008 - 63,884,027 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X81,542,853 - 81,566,259 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX59,352,186 - 59,375,591 (-)NCBICelera
Cytogenetic MapXq22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
17beta-estradiol  (ISO)
17beta-hydroxy-17-methylestra-4,9,11-trien-3-one  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,3,7,8-Tetrachlorodibenzofuran  (ISO)
2,4-dinitrotoluene  (EXP)
2,6-dinitrotoluene  (EXP)
2-amino-14,16-dimethyloctadecan-3-ol  (ISO)
3,4-methylenedioxymethamphetamine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-vinylcyclohexene dioxide  (ISO)
6-propyl-2-thiouracil  (EXP)
aconitine  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
amitrole  (EXP)
Aroclor 1254  (ISO)
arsane  (ISO)
arsenic atom  (ISO)
arsenite(3-)  (ISO)
benzatropine  (ISO)
benzo[a]pyrene  (ISO)
bisphenol A  (EXP,ISO)
bisphenol AF  (ISO)
Bisphenol B  (ISO)
bisphenol F  (ISO)
bortezomib  (ISO)
cadmium dichloride  (ISO)
calcitriol  (ISO)
captan  (ISO)
carbon nanotube  (ISO)
clozapine  (ISO)
enzyme inhibitor  (ISO)
epoxiconazole  (ISO)
ethanol  (ISO)
fenthion  (ISO)
ferroheme b  (ISO)
flutamide  (EXP)
folic acid  (ISO)
folpet  (ISO)
formaldehyde  (ISO)
furfural  (ISO)
glafenine  (EXP)
heme b  (ISO)
ivermectin  (ISO)
methimazole  (EXP)
methyl methanesulfonate  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
nefazodone  (EXP)
oxaliplatin  (EXP)
paracetamol  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
pirinixic acid  (ISO)
potassium chromate  (ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
progesterone  (ISO)
resveratrol  (ISO)
sodium arsenate  (ISO)
sodium arsenite  (ISO)
sodium chloride  (ISO)
sulfadimethoxine  (EXP)
sunitinib  (ISO)
tamibarotene  (ISO)
theophylline  (ISO)
titanium dioxide  (ISO)
topotecan  (EXP)
trimellitic anhydride  (ISO)
triphenyl phosphate  (ISO)
triptonide  (ISO)
vinclozolin  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Shape and location of eukaryotic initiation factor eIF-2 on the 40S ribosomal subunit of rat liver. Immunoelectron-microscopic and hydrodynamic investigations. Bommer UA, etal., Eur J Biochem. 1988 Mar 15;172(3):653-62.
2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
6. Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB. Young-Baird SK, etal., Mol Cell. 2020 Feb 20;77(4):875-886.e7. doi: 10.1016/j.molcel.2019.11.008. Epub 2019 Dec 10.
Additional References at PubMed
PMID:8780732   PMID:8889548   PMID:10900014   PMID:12426392   PMID:16289705   PMID:16854843   PMID:20458337   PMID:23063529   PMID:25468996  


Genomics

Comparative Map Data
Eif2s3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X62,910,292 - 62,933,936 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX62,910,293 - 62,934,489 (-)EnsemblGRCr8
mRatBN7.2X58,916,513 - 58,939,923 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX58,917,490 - 58,940,686 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX60,355,258 - 60,378,612 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X63,856,376 - 63,879,732 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X61,407,452 - 61,430,813 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X63,268,106 - 63,291,125 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX63,268,037 - 63,292,092 (-)Ensemblrn6Rnor6.0
Rnor_5.0X63,861,008 - 63,884,027 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X81,542,853 - 81,566,259 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX59,352,186 - 59,375,591 (-)NCBICelera
Cytogenetic MapXq22NCBI
EIF2S3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X24,054,956 - 24,078,810 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX24,054,911 - 24,078,810 (+)Ensemblhg38GRCh38
GRCh37X24,073,073 - 24,096,927 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X23,982,986 - 24,006,848 (+)NCBIBuild 36Build 36hg18NCBI36
Build 34X23,832,721 - 23,855,743NCBI
CeleraX28,196,181 - 28,220,053 (+)NCBICelera
Cytogenetic MapXp22.11NCBI
HuRefX21,816,175 - 21,839,574 (+)NCBIHuRef
CHM1_1X24,104,271 - 24,128,153 (+)NCBICHM1_1
T2T-CHM13v2.0X23,639,400 - 23,663,280 (+)NCBIT2T-CHM13v2.0
Eif2s3x
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X93,232,315 - 93,256,257 (-)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX93,232,313 - 93,256,468 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38X94,188,709 - 94,212,651 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX94,188,707 - 94,212,862 (-)Ensemblmm10GRCm38
MGSCv37X91,434,048 - 91,457,990 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X90,441,428 - 90,465,370 (-)NCBIMGSCv36mm8
CeleraX81,110,914 - 81,134,502 (-)NCBICelera
Cytogenetic MapXC3NCBI
cM MapX41.52NCBI
Eif2s3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555094,436,750 - 4,457,819 (+)Ensembl
ChiLan1.0NW_0049555094,437,044 - 4,457,819 (+)NCBIChiLan1.0ChiLan1.0
EIF2S3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X25,854,961 - 25,879,113 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X25,858,835 - 25,882,502 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X16,653,762 - 16,678,198 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X24,027,099 - 24,050,879 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX24,027,099 - 24,050,879 (+)EnsemblpanPan2panpan1.1
EIF2S3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X19,662,132 - 19,680,223 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX19,650,343 - 19,680,221 (+)EnsemblcanFam3CanFam3.1
ROS_Cfam_1.0X19,617,765 - 19,635,846 (+)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX19,605,975 - 19,637,812 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X19,656,521 - 19,674,614 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X19,689,972 - 19,708,341 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X19,746,165 - 19,764,509 (+)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Eif2s3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X12,622,024 - 12,641,621 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936624515,864 - 535,981 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936624516,206 - 535,749 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
EIF2S3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX20,146,933 - 20,162,702 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X20,129,708 - 20,162,881 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X21,554,153 - 21,587,126 (+)NCBISscrofa10.2Sscrofa10.2susScr3
EIF2S3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X22,523,330 - 22,549,827 (+)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366605624,404,897 - 24,429,467 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Eif2s3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_004624897424,144 - 445,698 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
Eif2s3
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X52,101,578 - 52,124,302 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Eif2s3
48 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:112
Count of miRNA genes:93
Interacting mature miRNAs:97
Transcripts:ENSRNOT00000058134
Prediction methods:Microtar, Miranda, Pita, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
738035Stresp1Stress response QTL 14.960.000011stress-related behavior trait (VT:0010451)defensive burying - copingX45182909117740458Rat
70221Bp56Blood pressure QTL 564.9arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X6103585667175160Rat
1598837Memor13Memory QTL 133.2exploratory behavior trait (VT:0010471)difference between duration of physical contact or close proximity of test subject and social stimulus during sample phase and test phase (CMO:0002678)X4493088389930883Rat

Markers in Region
RH17627  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X58,922,335 - 58,923,518 (+)MAPPERmRatBN7.2
Rnor_6.0X63,273,928 - 63,275,110NCBIRnor6.0
Rnor_5.0X63,866,830 - 63,868,012UniSTSRnor5.0
RGSC_v3.4X81,548,676 - 81,549,858UniSTSRGSC3.4
CeleraX59,358,008 - 59,359,190UniSTS
Cytogenetic MapXq31UniSTS
EIF2S3  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2X58,923,467 - 58,923,572 (+)MAPPERmRatBN7.2
Rnor_6.0X63,275,060 - 63,275,164NCBIRnor6.0
Rnor_5.0X63,867,962 - 63,868,066UniSTSRnor5.0
RGSC_v3.4X81,549,808 - 81,549,912UniSTSRGSC3.4
CeleraX59,359,140 - 59,359,244UniSTS
Cytogenetic MapXq31UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence


Ensembl Acc Id: ENSRNOT00000081124   ⟹   ENSRNOP00000072851
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX62,932,866 - 62,934,489 (-)Ensembl
mRatBN7.2 EnsemblX58,938,675 - 58,940,686 (-)Ensembl
Rnor_6.0 EnsemblX63,288,363 - 63,292,092 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000082421   ⟹   ENSRNOP00000074806
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX62,910,293 - 62,934,140 (-)Ensembl
mRatBN7.2 EnsemblX58,917,490 - 58,940,165 (-)Ensembl
Rnor_6.0 EnsemblX63,281,779 - 63,291,371 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000092019   ⟹   ENSRNOP00000070817
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX62,910,293 - 62,933,699 (-)Ensembl
mRatBN7.2 EnsemblX58,917,490 - 58,939,913 (-)Ensembl
Rnor_6.0 EnsemblX63,268,037 - 63,291,107 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000114488   ⟹   ENSRNOP00000087240
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 EnsemblX58,917,490 - 58,939,909 (-)Ensembl
RefSeq Acc Id: NM_001100542   ⟹   NP_001094012
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X62,910,292 - 62,933,699 (-)NCBI
mRatBN7.2X58,916,513 - 58,939,923 (-)NCBI
Rnor_6.0X63,268,106 - 63,291,125 (-)NCBI
Rnor_5.0X63,861,008 - 63,884,027 (-)NCBI
RGSC_v3.4X81,542,853 - 81,566,259 (-)RGD
CeleraX59,352,186 - 59,375,591 (-)RGD
Sequence:
RefSeq Acc Id: XM_063279877   ⟹   XP_063135947
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X62,911,269 - 62,933,936 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001094012 (Get FASTA)   NCBI Sequence Viewer  
  XP_063135947 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH91286 (Get FASTA)   NCBI Sequence Viewer  
  AAI66783 (Get FASTA)   NCBI Sequence Viewer  
  EDL96007 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000070817
  ENSRNOP00000087240.1
GenBank Protein P81795 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001094012   ⟸   NM_001100542
- UniProtKB: B2RYH8 (UniProtKB/Swiss-Prot),   B0BN96 (UniProtKB/Swiss-Prot),   Q5BJX8 (UniProtKB/Swiss-Prot),   P81795 (UniProtKB/Swiss-Prot),   A0A8L2R4R9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000070817   ⟸   ENSRNOT00000092019
Ensembl Acc Id: ENSRNOP00000074806   ⟸   ENSRNOT00000082421
Ensembl Acc Id: ENSRNOP00000072851   ⟸   ENSRNOT00000081124
Ensembl Acc Id: ENSRNOP00000087240   ⟸   ENSRNOT00000114488
RefSeq Acc Id: XP_063135947   ⟸   XM_063279877
- Peptide Label: isoform X1
- UniProtKB: Q5BJX8 (UniProtKB/Swiss-Prot),   P81795 (UniProtKB/Swiss-Prot),   B2RYH8 (UniProtKB/Swiss-Prot),   B0BN96 (UniProtKB/Swiss-Prot),   A0A8L2R4R9 (UniProtKB/TrEMBL)
Protein Domains
tr-type G

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P81795-F1-model_v2 AlphaFold P81795 1-472 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701840
Promoter ID:EPDNEW_R12364
Type:multiple initiation site
Name:Eif2s3_1
Description:eukaryotic translation initiation factor 2 subunit gamma
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X63,291,120 - 63,291,180EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561279 AgrOrtholog
BioCyc Gene G2FUF-2247 BioCyc
Ensembl Genes ENSRNOG00000060793 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000092019 ENTREZGENE
  ENSRNOT00000114488.1 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
  Translation factors UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7304876 IMAGE-MGC_LOAD
  IMAGE:7935021 IMAGE-MGC_LOAD
  IMAGE:9098876 IMAGE-MGC_LOAD
InterPro EFTu-like_2 UniProtKB/Swiss-Prot
  eIF2G UniProtKB/Swiss-Prot
  eIF2g_dom_2 UniProtKB/Swiss-Prot
  eIF2g_GTP-bd UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
  TF_GTP-bd_dom UniProtKB/Swiss-Prot
  TIF2_gsu_C UniProtKB/Swiss-Prot
  Transl_B-barrel_sf UniProtKB/Swiss-Prot
  Transl_elong_EF1A/Init_IF2_C UniProtKB/Swiss-Prot
KEGG Report rno:299027 UniProtKB/Swiss-Prot
MGC_CLONE MGC:109183 IMAGE-MGC_LOAD
  MGC:187904 IMAGE-MGC_LOAD
  MGC:188564 IMAGE-MGC_LOAD
NCBI Gene 299027 ENTREZGENE
PANTHER EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3 FAMILY MEMBER UniProtKB/Swiss-Prot
  EUKARYOTIC TRANSLATION INITIATION FACTOR 2 SUBUNIT 3-RELATED UniProtKB/Swiss-Prot
Pfam eIF2_C UniProtKB/Swiss-Prot
  GTP_EFTU UniProtKB/Swiss-Prot
  GTP_EFTU_D2 UniProtKB/Swiss-Prot
PhenoGen Eif2s3 PhenoGen
PRINTS ELONGATNFCT UniProtKB/Swiss-Prot
PROSITE G_TR_2 UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000060793 RatGTEx
Superfamily-SCOP SSF50447 UniProtKB/Swiss-Prot
  SSF50465 UniProtKB/Swiss-Prot
  SSF52540 UniProtKB/Swiss-Prot
UniProt A0A096MJB9_RAT UniProtKB/TrEMBL
  A0A1P0QU16_RAT UniProtKB/TrEMBL
  A0A8L2R4R9 ENTREZGENE, UniProtKB/TrEMBL
  B0BN96 ENTREZGENE
  B2RYH8 ENTREZGENE
  IF2G_RAT UniProtKB/Swiss-Prot, ENTREZGENE
  Q5BJX8 ENTREZGENE
UniProt Secondary B0BN96 UniProtKB/Swiss-Prot
  B2RYH8 UniProtKB/Swiss-Prot
  Q5BJX8 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-09-09 Eif2s3  eukaryotic translation initiation factor 2 subunit gamma  Eif2s3  eukaryotic translation initiation factor 2, subunit 3 gamma  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-01-11 Eif2s3  eukaryotic translation initiation factor 2, subunit 3 gamma  Eif2s3x  eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Eif2s3x  eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked      Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 Eif2s3x  eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked      Symbol and Name status set to provisional 70820 PROVISIONAL