LY6G5C (lymphocyte antigen 6 family member G5C) - Rat Genome Database

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Gene: LY6G5C (lymphocyte antigen 6 family member G5C) Homo sapiens
Analyze
Symbol: LY6G5C
Name: lymphocyte antigen 6 family member G5C
RGD ID: 1346509
HGNC Page HGNC:13932
Description: Enables identical protein binding activity. Located in external side of plasma membrane. Part of protein-containing complex.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C6orf20; G5c; LY6G5CA; LY6G5CB; lymphocyte antigen 6 complex locus protein G5c; lymphocyte antigen 6 complex, locus G5C; lymphocyte antigen-6 G5C; NG33
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,676,684 - 31,681,067 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,676,684 - 31,684,040 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,644,461 - 31,648,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,752,440 - 31,756,120 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,752,439 - 31,756,120NCBI
Celera633,242,682 - 33,246,372 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,430,686 - 31,434,376 (-)NCBIHuRef
CHM1_1631,646,597 - 31,650,286 (-)NCBICHM1_1
T2T-CHM13v2.0631,529,718 - 31,534,101 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12079290   PMID:17008713   PMID:17192395   PMID:18835879   PMID:19851445   PMID:21873635   PMID:32877691   PMID:33961781  


Genomics

Comparative Map Data
LY6G5C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38631,676,684 - 31,681,067 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl631,676,684 - 31,684,040 (-)EnsemblGRCh38hg38GRCh38
GRCh37631,644,461 - 31,648,844 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36631,752,440 - 31,756,120 (-)NCBINCBI36Build 36hg18NCBI36
Build 34631,752,439 - 31,756,120NCBI
Celera633,242,682 - 33,246,372 (-)NCBICelera
Cytogenetic Map6p21.33NCBI
HuRef631,430,686 - 31,434,376 (-)NCBIHuRef
CHM1_1631,646,597 - 31,650,286 (-)NCBICHM1_1
T2T-CHM13v2.0631,529,718 - 31,534,101 (-)NCBIT2T-CHM13v2.0
Ly6g5c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391735,327,270 - 35,331,149 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1735,327,255 - 35,330,967 (+)EnsemblGRCm39 Ensembl
GRCm381735,108,294 - 35,112,173 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1735,108,279 - 35,111,991 (+)EnsemblGRCm38mm10GRCm38
MGSCv371735,245,245 - 35,248,898 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361734,716,356 - 34,720,009 (+)NCBIMGSCv36mm8
Celera1738,204,977 - 38,208,905 (+)NCBICelera
Cytogenetic Map17B1NCBI
cM Map1718.59NCBI
Ly6g5c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8203,714,094 - 3,718,861 (-)NCBIGRCr8
mRatBN7.2203,709,426 - 3,713,940 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl203,709,529 - 3,713,608 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx204,408,433 - 4,412,527 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0203,770,489 - 3,774,583 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0204,308,362 - 4,312,653 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0205,100,415 - 5,104,631 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl205,100,415 - 5,104,494 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0207,173,674 - 7,177,753 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4203,773,183 - 3,777,262 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1203,773,409 - 3,777,489 (-)NCBI
Celera204,312,034 - 4,316,113 (+)NCBICelera
Cytogenetic Map20p12NCBI
Ly6g5c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_004955437220,428 - 223,636 (-)EnsemblChiLan1.0
ChiLan1.0NW_004955437220,603 - 223,636 (-)NCBIChiLan1.0ChiLan1.0
LY6G5C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2546,153,713 - 46,164,355 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1642,115,061 - 42,125,868 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0631,337,846 - 31,343,226 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1632,227,629 - 32,233,058 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl632,227,629 - 32,231,409 (-)Ensemblpanpan1.1panPan2
LY6G5C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1121,159,598 - 1,163,526 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl121,159,598 - 1,163,526 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha121,296,174 - 1,300,102 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0121,304,967 - 1,309,728 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl121,304,969 - 1,308,899 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1121,164,273 - 1,168,198 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0121,231,445 - 1,235,371 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0121,298,663 - 1,302,592 (-)NCBIUU_Cfam_GSD_1.0
Ly6g5c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494635,708,691 - 35,714,120 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367271,848,505 - 1,852,398 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367271,848,502 - 1,852,659 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LY6G5C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl723,791,198 - 23,795,734 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1723,791,160 - 23,795,967 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2727,451,630 - 27,460,718 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LY6G5C
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11740,342,875 - 40,348,537 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1740,344,510 - 40,348,254 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604431,587,130 - 31,592,410 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ly6g5c
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462475424,526,003 - 24,528,280 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in LY6G5C
5 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 6p25.3-12.3(chr6:156974-46789291)x3 copy number gain See cases [RCV000143497] Chr6:156974..46789291 [GRCh38]
Chr6:156974..46757028 [GRCh37]
Chr6:101974..46864987 [NCBI36]
Chr6:6p25.3-12.3		 pathogenic
GRCh37/hg19 6p21.33(chr6:31384577-31902308)x3 copy number gain See cases [RCV000448679] Chr6:31384577..31902308 [GRCh37]
Chr6:6p21.33		 uncertain significance
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482)x3 copy number gain See cases [RCV000512067] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:156975-170919482) copy number gain See cases [RCV000510595] Chr6:156975..170919482 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:108666-170980171)x3 copy number gain not provided [RCV000745403] Chr6:108666..170980171 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:60107-171054786)x3 copy number gain not provided [RCV000745400] Chr6:60107..171054786 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p25.3-q27(chr6:165632-170919470)x3 copy number gain not provided [RCV000745404] Chr6:165632..170919470 [GRCh37]
Chr6:6p25.3-q27		 pathogenic
GRCh37/hg19 6p22.1-21.32(chr6:28130359-32108367)x3 copy number gain not provided [RCV000745592] Chr6:28130359..32108367 [GRCh37]
Chr6:6p22.1-21.32		 uncertain significance
GRCh37/hg19 6p22.1-q14.1(chr6:29455465-81447367) copy number gain not provided [RCV000767714] Chr6:29455465..81447367 [GRCh37]
Chr6:6p22.1-q14.1		 pathogenic
GRCh37/hg19 6p21.33-21.31(chr6:31036397-34088832)x3 copy number gain not provided [RCV001005791] Chr6:31036397..34088832 [GRCh37]
Chr6:6p21.33-21.31		 likely pathogenic
NC_000006.11:g.(?_30695893)_(31937492_?)dup duplication not provided [RCV003107453] Chr6:30695893..31937492 [GRCh37]
Chr6:6p21.33		 uncertain significance
NC_000006.11:g.28005012_31683185del deletion Megacolon [RCV001290055] Chr6:28005012..31683185 [GRCh37]
Chr6:6p22.1-21.33		 likely pathogenic
GRCh37/hg19 6p21.33(chr6:31384577-31902308) copy number gain not specified [RCV002053564] Chr6:31384577..31902308 [GRCh37]
Chr6:6p21.33		 uncertain significance
NC_000006.11:g.(?_30695893)_(36953949_?)dup duplication Proteasome-associated autoinflammatory syndrome 1 [RCV003113679] Chr6:30695893..36953949 [GRCh37]
Chr6:6p21.33-21.2		 uncertain significance
NM_025262.4(LY6G5C):c.309G>A (p.Met103Ile) single nucleotide variant Inborn genetic diseases [RCV002728404] Chr6:31677101 [GRCh38]
Chr6:31644878 [GRCh37]
Chr6:6p21.33		 uncertain significance
NM_025262.4(LY6G5C):c.339G>A (p.Met113Ile) single nucleotide variant Inborn genetic diseases [RCV003010773] Chr6:31677071 [GRCh38]
Chr6:31644848 [GRCh37]
Chr6:6p21.33		 uncertain significance
NM_025262.4(LY6G5C):c.71C>A (p.Ala24Asp) single nucleotide variant Inborn genetic diseases [RCV002718903] Chr6:31680303 [GRCh38]
Chr6:31648080 [GRCh37]
Chr6:6p21.33		 uncertain significance
NM_025262.4(LY6G5C):c.368C>T (p.Pro123Leu) single nucleotide variant Inborn genetic diseases [RCV003375797] Chr6:31677042 [GRCh38]
Chr6:31644819 [GRCh37]
Chr6:6p21.33		 uncertain significance
NM_025262.4(LY6G5C):c.123T>C (p.Gly41=) single nucleotide variant not provided [RCV003431758] Chr6:31679267 [GRCh38]
Chr6:31647044 [GRCh37]
Chr6:6p21.33		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2374
Count of miRNA genes:727
Interacting mature miRNAs:830
Transcripts:ENST00000375858, ENST00000375860, ENST00000375863, ENST00000383237, ENST00000460141, ENST00000461572, ENST00000467098, ENST00000474395, ENST00000474678
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
RH15840  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37631,648,463 - 31,648,616UniSTSGRCh37
Build 36631,756,442 - 31,756,595RGDNCBI36
Celera633,246,685 - 33,246,838RGD
Cytogenetic Map6p21.33UniSTS
HuRef631,434,689 - 31,434,842UniSTS
GeneMap99-GB4 RH Map6119.82UniSTS
D1S1425  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map1p33UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map5q35.3UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map4q21.23UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map11q13UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map10q22UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map10p14UniSTS
Cytogenetic Map6p21.33UniSTS
Cytogenetic Map10q26.3UniSTS
Cytogenetic Map7q22.1UniSTS
Cytogenetic Map19q13.32UniSTS
Cytogenetic Map17q21.31UniSTS
Cytogenetic Map7p22.2UniSTS
Cytogenetic Map12q13.12UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map14q32.12UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map18p11.31UniSTS
Cytogenetic Map13q34UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map8q12.1UniSTS
Cytogenetic Map11q12.3UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map10p12UniSTS
Cytogenetic Map12q13UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map8q24UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map5q32UniSTS
Cytogenetic Map1q21.2UniSTS
Cytogenetic Map3q26.2UniSTS
Cytogenetic Map6q25.2-q25.3UniSTS
Cytogenetic Map20q11.2-q13.2UniSTS
Cytogenetic Map12q13.3UniSTS
Cytogenetic Map1q21-q23UniSTS
Cytogenetic Map17q21.32UniSTS
Cytogenetic Map1p35.3UniSTS
Cytogenetic Map1p12UniSTS
Cytogenetic Map2p23-p22UniSTS
Cytogenetic Map2q36.1UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map2p16.1UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map16q12.1UniSTS
Cytogenetic Map17q22-q23UniSTS
Cytogenetic Map2p11.1UniSTS
Cytogenetic Map16q12.2UniSTS
Cytogenetic Map2p12-p11.2UniSTS
Cytogenetic Map3q11.1UniSTS
Cytogenetic Map2p21UniSTS
Cytogenetic Map17q11.2-q12UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map1p32-p31UniSTS
Cytogenetic Map1p21.3UniSTS
Cytogenetic Map1q32.2UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map7q21-q22UniSTS
Cytogenetic Map1q25.3UniSTS
Cytogenetic Map18p11.3-p11.2UniSTS
Cytogenetic Map2q33.2UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map21p11.1UniSTS
Cytogenetic Map12q24.31-q24.32UniSTS
Cytogenetic Map9q33.2UniSTS
Cytogenetic Map11q13.5UniSTS
Cytogenetic Map12p12.2-p11.2UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map2q14.3UniSTS
Cytogenetic Map19p13.3-p13.2UniSTS
Cytogenetic Map7q32.1UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map17q22-q23.2UniSTS
Cytogenetic Map3q27.1UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map4q21.21UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map14q32UniSTS
Cytogenetic Map14q24.2UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map3p21UniSTS
Cytogenetic Map10p11.23UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map1q25.2UniSTS
Cytogenetic Map18q12.1UniSTS
Cytogenetic Map1p34.3UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map15q23UniSTS
Cytogenetic Map8q24.3UniSTS
Cytogenetic Map13q12.11UniSTS
Cytogenetic Map1p36.31UniSTS
Cytogenetic Map3q21.1UniSTS
Cytogenetic Map12p12UniSTS
Cytogenetic Map21q22.11UniSTS
Cytogenetic Map15q15.3UniSTS
Cytogenetic MapXq12-q13UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map7q31.1-q31.3UniSTS
Cytogenetic MapXp22.11UniSTS
Cytogenetic Map3p21.1-p14.2UniSTS
Cytogenetic Map2p24UniSTS
Cytogenetic Map20p12.1UniSTS
Cytogenetic Map3q26.33UniSTS
Cytogenetic Map12q13.11-q14.3UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map9q21.33UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic MapXq13-q21UniSTS
Cytogenetic Map8q24.22UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map6q25.2-q27UniSTS
Cytogenetic Map12q24.32UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic MapXq13.1UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map14q12UniSTS
Cytogenetic Map12q23-q24.1UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map17q24.1UniSTS
Cytogenetic Map17p13.3UniSTS
Cytogenetic Map14q21UniSTS
Cytogenetic Map9p24.3UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map2p14UniSTS
Cytogenetic Map21q22.2UniSTS
Cytogenetic Map2q12.3UniSTS
Cytogenetic Map8p21.1UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map3q25.33UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map1p34UniSTS
Cytogenetic Map19p13.1UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic MapXq22.3UniSTS
Cytogenetic Map7p21.1UniSTS
Cytogenetic Map6p25.2UniSTS
Cytogenetic Map10q23.33UniSTS
Cytogenetic Map15q11-q12UniSTS
Cytogenetic Map3p22.2UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map15q21.1-q21.2UniSTS
Cytogenetic Map6p21.3UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map4q13.3UniSTS
Cytogenetic Map19p13.13UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map17q24.3UniSTS
Cytogenetic Map12p13.33UniSTS
Cytogenetic Map11q14.1UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map16q22.3UniSTS
Cytogenetic Map1p22.1UniSTS
Cytogenetic Map6p12.1UniSTS
Cytogenetic Map19q13.33-q13.41UniSTS
Cytogenetic Map2p25.3UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map5p12UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map7q35UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map7q11.1UniSTS
Cytogenetic Map2p25.1-p24.1UniSTS
Cytogenetic Map3q23UniSTS
Cytogenetic Map4q31.21UniSTS
Cytogenetic Map5p13.1UniSTS
Cytogenetic MapXq22.1UniSTS
Cytogenetic Map9q21.11UniSTS
Cytogenetic Map5q13UniSTS
Cytogenetic Map1p22.2UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map12q24UniSTS
Cytogenetic MapXq24UniSTS
Cytogenetic Map1q24.2UniSTS
Cytogenetic Map22q13.31UniSTS
Cytogenetic Map8p11.23UniSTS
Cytogenetic Map1q23.3UniSTS
Cytogenetic Map16p12UniSTS
Cytogenetic Map10p15-p14UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map1q22-q23UniSTS
Cytogenetic Map20q11.23UniSTS
Cytogenetic Map7q31UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map7p22.1UniSTS
Cytogenetic Map6p22.3UniSTS
Cytogenetic Map6p21.2UniSTS
Cytogenetic Map11q13.4UniSTS
Cytogenetic Map11q24.2UniSTS
Cytogenetic MapXq28UniSTS
Cytogenetic Map1p33-p32UniSTS
Cytogenetic Map5q35.2UniSTS
Cytogenetic Map3p14.3UniSTS
Cytogenetic Map12q24.33UniSTS
Cytogenetic Map3q26.1-q26.2UniSTS
Cytogenetic Map12p13UniSTS
Cytogenetic Map7q36.1UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic Map12q13.1-q13.2UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map19q13.33UniSTS
Cytogenetic Map16p12.3UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map9p13.2UniSTS
Cytogenetic Map4q22.1UniSTS
Cytogenetic Map3q13.2UniSTS
Cytogenetic Map8p22UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map1q42.3UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map5q12.3UniSTS
Cytogenetic Map20q11.21UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic Map6q15UniSTS
Cytogenetic Map6q22.32UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map19q13.31UniSTS
Cytogenetic Map16p13.11UniSTS
Cytogenetic Map10q24.32UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map18q11.1UniSTS
Cytogenetic Map16q23.2UniSTS
Cytogenetic Map3q12.1UniSTS
Cytogenetic Map15q24-q25UniSTS
Cytogenetic Map7q31.1UniSTS
Cytogenetic Map15q26.1UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map6pter-p12.1UniSTS
Cytogenetic Map6q16UniSTS
Cytogenetic Map12q14.1UniSTS
Cytogenetic Map17q21.2UniSTS
Cytogenetic Map9q22.2UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map11q23.1-q23.2UniSTS
Cytogenetic Map13q14UniSTS
Cytogenetic Map4q23UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map11q24.3UniSTS
Cytogenetic Map7p14UniSTS
Cytogenetic Map15q24.1UniSTS
Cytogenetic Map16q24.2UniSTS
Cytogenetic Map12q13.11UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map5p15.2UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map2q13UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map20p13UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map5q23.3-q31.1UniSTS
Cytogenetic Map1p36UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map2q35UniSTS
Cytogenetic Map17p11.2UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map12p13.31UniSTS
Cytogenetic Map3q12.3UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map20q11UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map5q23.3UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map1q42UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map14q21.3UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map20q13.32UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic MapXq21.1UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 1 38 37 48 1 495 347 11
Low 2424 2884 1629 568 1827 409 4258 2138 3223 387 1093 1580 174 1 1202 2755 3 2
Below cutoff 12 69 60 56 71 56 97 58 14 31 19 22 2 33 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_025262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331185 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054331427 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AA179679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AA731226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF129756 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ315540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ315541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ315542 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ315543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ315544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL662899 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL670886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL805934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BA000025 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX511262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068272 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR354443 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR753842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR759761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500421 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY500422 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000375863   ⟹   ENSP00000365023
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl631,676,684 - 31,684,040 (-)Ensembl
RefSeq Acc Id: ENST00000383237   ⟹   ENSP00000372724
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl631,676,684 - 31,681,067 (-)Ensembl
RefSeq Acc Id: ENST00000460141
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl631,676,957 - 31,680,364 (-)Ensembl
RefSeq Acc Id: ENST00000461572
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl631,681,348 - 31,681,960 (-)Ensembl
RefSeq Acc Id: ENST00000467098
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl631,676,848 - 31,684,040 (-)Ensembl
RefSeq Acc Id: ENST00000474395
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl631,676,700 - 31,681,476 (-)Ensembl
RefSeq Acc Id: ENST00000474678   ⟹   ENSP00000418172
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl631,676,957 - 31,680,364 (-)Ensembl
RefSeq Acc Id: NM_025262   ⟹   NP_079538
RefSeq Status: VALIDATED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38631,676,684 - 31,681,067 (-)NCBI
GRCh37631,644,461 - 31,648,150 (-)RGD
Build 36631,752,440 - 31,756,120 (-)NCBI Archive
Celera633,242,682 - 33,246,372 (-)RGD
HuRef631,430,686 - 31,434,376 (-)RGD
CHM1_1631,646,597 - 31,650,286 (-)NCBI
T2T-CHM13v2.0631,529,718 - 31,534,101 (-)NCBI
Sequence:
Reference Protein Sequences
RefSeq Acc Id: NP_079538   ⟸   NM_025262
- Peptide Label: precursor
- UniProtKB: Q8NDY0 (UniProtKB/Swiss-Prot),   Q5SQ59 (UniProtKB/Swiss-Prot),   O95871 (UniProtKB/Swiss-Prot),   B1B0L9 (UniProtKB/Swiss-Prot),   B0UZQ0 (UniProtKB/Swiss-Prot),   B0UZ69 (UniProtKB/Swiss-Prot),   B0UXB4 (UniProtKB/Swiss-Prot),   B0UXB3 (UniProtKB/Swiss-Prot),   A6NCW4 (UniProtKB/Swiss-Prot),   Q8NDY1 (UniProtKB/Swiss-Prot),   Q5SRR4 (UniProtKB/Swiss-Prot),   A0A1U9X7Y6 (UniProtKB/TrEMBL),   A0A1U9X7Z9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000365023   ⟸   ENST00000375863
RefSeq Acc Id: ENSP00000418172   ⟸   ENST00000474678
RefSeq Acc Id: ENSP00000372724   ⟸   ENST00000383237
Protein Domains
UPAR/Ly6

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5SRR4-F1-model_v2 AlphaFold Q5SRR4 1-150 view protein structure

Promoters
RGD ID:6813024
Promoter ID:HG_ACW:67968
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:LY6G5C.EAPR07-UNSPLICED
Position:
Human AssemblyChrPosition (strand)Source
Build 36631,752,466 - 31,752,966 (-)MPROMDB
RGD ID:6804425
Promoter ID:HG_KWN:52963
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   K562,   Lymphoblastoid
Transcripts:ENST00000383237,   OTTHUMT00000127863,   OTTHUMT00000127864
Position:
Human AssemblyChrPosition (strand)Source
Build 36631,756,469 - 31,756,969 (-)MPROMDB
RGD ID:6804423
Promoter ID:HG_KWN:52964
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000127866,   OTTHUMT00000268010
Position:
Human AssemblyChrPosition (strand)Source
Build 36631,756,886 - 31,757,386 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:13932 AgrOrtholog
COSMIC LY6G5C COSMIC
Ensembl Genes ENSG00000111971 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000204428 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000206404 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000226404 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000228883 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000231325 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ENSG00000237495 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000324540.9 UniProtKB/Swiss-Prot
  ENST00000375863.7 UniProtKB/TrEMBL
  ENST00000383237 ENTREZGENE
  ENST00000383237.5 UniProtKB/Swiss-Prot
  ENST00000383425.8 UniProtKB/Swiss-Prot
  ENST00000411492.1 UniProtKB/TrEMBL
  ENST00000418117.6 UniProtKB/Swiss-Prot
  ENST00000431114.6 UniProtKB/Swiss-Prot
  ENST00000432980.1 UniProtKB/TrEMBL
  ENST00000435280.1 UniProtKB/TrEMBL
  ENST00000449562.1 UniProtKB/TrEMBL
  ENST00000449871.1 UniProtKB/TrEMBL
  ENST00000450798.1 UniProtKB/TrEMBL
  ENST00000455753.6 UniProtKB/Swiss-Prot
  ENST00000458081.6 UniProtKB/Swiss-Prot
  ENST00000474678.5 UniProtKB/TrEMBL
GTEx ENSG00000111971 GTEx
  ENSG00000204428 GTEx
  ENSG00000206404 GTEx
  ENSG00000226404 GTEx
  ENSG00000228883 GTEx
  ENSG00000231325 GTEx
  ENSG00000237495 GTEx
HGNC ID HGNC:13932 ENTREZGENE
Human Proteome Map LY6G5C Human Proteome Map
InterPro LY6G5C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:80741 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 80741 ENTREZGENE
OMIM 610434 OMIM
PANTHER LYMPHOCYTE ANTIGEN 6 COMPLEX LOCUS PROTEIN G5C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR14909 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA37827 PharmGKB
UniProt A0A140T929_HUMAN UniProtKB/TrEMBL
  A0A140T9A4_HUMAN UniProtKB/TrEMBL
  A0A140T9E2_HUMAN UniProtKB/TrEMBL
  A0A140T9E8_HUMAN UniProtKB/TrEMBL
  A0A140T9H6_HUMAN UniProtKB/TrEMBL
  A0A140T9R3_HUMAN UniProtKB/TrEMBL
  A0A1U9X7Y6 ENTREZGENE, UniProtKB/TrEMBL
  A0A1U9X7Z9 ENTREZGENE, UniProtKB/TrEMBL
  A6NCW4 ENTREZGENE
  B0UXB3 ENTREZGENE
  B0UXB4 ENTREZGENE
  B0UZ69 ENTREZGENE
  B0UZQ0 ENTREZGENE
  B1B0L9 ENTREZGENE
  F8WBQ4_HUMAN UniProtKB/TrEMBL
  H7BYB1_HUMAN UniProtKB/TrEMBL
  LY65C_HUMAN UniProtKB/Swiss-Prot
  O95871 ENTREZGENE
  Q5SQ59 ENTREZGENE
  Q5SRR4 ENTREZGENE
  Q8NDY0 ENTREZGENE
  Q8NDY1 ENTREZGENE
UniProt Secondary A6NCW4 UniProtKB/Swiss-Prot
  B0UXB3 UniProtKB/Swiss-Prot
  B0UXB4 UniProtKB/Swiss-Prot
  B0UZ69 UniProtKB/Swiss-Prot
  B0UZQ0 UniProtKB/Swiss-Prot
  B1B0L9 UniProtKB/Swiss-Prot
  O95871 UniProtKB/Swiss-Prot
  Q5SQ59 UniProtKB/Swiss-Prot
  Q8NDY0 UniProtKB/Swiss-Prot
  Q8NDY1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-01-31 LY6G5C  lymphocyte antigen 6 family member G5C  LY6G5C  lymphocyte antigen 6 complex, locus G5C  Symbol and/or name change 5135510 APPROVED