Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Nr2c2ap | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NR2C2AP mRNA] | CTD | PMID:31150632 | Nr2c2ap | Rat | (-)-epigallocatechin 3-gallate | multiple interactions | ISO | NR2C2AP (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NR2C2AP mRNA | CTD | PMID:22079256 | Nr2c2ap | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Nr2c2ap (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NR2C2AP mRNA | CTD | PMID:22206623 | Nr2c2ap | Rat | 1,2-dimethylhydrazine | increases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in increased expression of NR2C2AP mRNA | CTD | PMID:22206623 | Nr2c2ap | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of NR2C2AP mRNA | CTD | PMID:21570461 | Nr2c2ap | Rat | 2,3,7,8-Tetrachlorodibenzofuran | increases expression | EXP | | 6480464 | 2 more ... | CTD | PMID:32109520 | Nr2c2ap | Rat | 4,4'-sulfonyldiphenol | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NR2C2AP mRNA | CTD | PMID:36041667 | Nr2c2ap | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | Fenretinide results in decreased expression of NR2C2AP mRNA | CTD | PMID:28973697 | Nr2c2ap | Rat | aflatoxin B1 | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of NR2C2AP mRNA | CTD | PMID:22100608 | Nr2c2ap | Rat | all-trans-retinoic acid | decreases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Tretinoin results in decreased expression of NR2C2AP mRNA | CTD | PMID:23724009 | Nr2c2ap | Rat | benzo[a]pyrene | decreases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of NR2C2AP mRNA | CTD | PMID:19770486 | Nr2c2ap | Rat | benzo[a]pyrene | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of NR2C2AP mRNA | CTD | PMID:32234424 | Nr2c2ap | Rat | benzo[a]pyrene | decreases methylation | ISO | NR2C2AP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of NR2C2AP 3' UTR | CTD | PMID:27901495 | Nr2c2ap | Rat | benzo[a]pyrene | increases methylation | ISO | NR2C2AP (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of NR2C2AP promoter | CTD | PMID:27901495 | Nr2c2ap | Rat | benzo[a]pyrene | increases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of NR2C2AP mRNA | CTD | PMID:22228805 | Nr2c2ap | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of NR2C2AP mRNA | CTD | PMID:25181051 and PMID:34947998 | Nr2c2ap | Rat | bisphenol A | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NR2C2AP mRNA | CTD | PMID:36041667 | Nr2c2ap | Rat | bisphenol A | increases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | bisphenol A results in increased expression of NR2C2AP mRNA | CTD | PMID:33221593 and PMID:38074096 | Nr2c2ap | Rat | bisphenol F | multiple interactions | EXP | | 6480464 | [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in decreased expression of NR2C2AP mRNA | CTD | PMID:36041667 | Nr2c2ap | Rat | calcitriol | decreases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Calcitriol results in decreased expression of NR2C2AP mRNA | CTD | PMID:21592394 | Nr2c2ap | Rat | calcitriol | multiple interactions | ISO | NR2C2AP (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of NR2C2AP mRNA | CTD | PMID:21592394 | Nr2c2ap | Rat | chlorpyrifos | increases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | Chlorpyrifos results in increased expression of NR2C2AP mRNA | CTD | PMID:37019170 | Nr2c2ap | Rat | chromium(6+) | decreases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | chromium hexavalent ion results in decreased expression of NR2C2AP mRNA | CTD | PMID:30690063 | Nr2c2ap | Rat | cisplatin | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Cisplatin results in increased expression of NR2C2AP mRNA | CTD | PMID:27392435 | Nr2c2ap | Rat | coumestrol | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Coumestrol results in increased expression of NR2C2AP mRNA | CTD | PMID:19167446 | Nr2c2ap | Rat | cyclosporin A | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of NR2C2AP mRNA | CTD | PMID:25562108 | Nr2c2ap | Rat | DDE | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Dichlorodiphenyl Dichloroethylene results in increased expression of NR2C2AP mRNA | CTD | PMID:38568856 | Nr2c2ap | Rat | Dibutyl phosphate | affects expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of NR2C2AP mRNA | CTD | PMID:37042841 | Nr2c2ap | Rat | dibutyl phthalate | decreases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | Dibutyl Phthalate results in decreased expression of NR2C2AP mRNA | CTD | PMID:21266533 | Nr2c2ap | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of NR2C2AP mRNA | CTD | PMID:29391264 | Nr2c2ap | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of NR2C2AP mRNA | CTD | PMID:24136188 | Nr2c2ap | Rat | folic acid | decreases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | Folic Acid results in decreased expression of NR2C2AP mRNA | CTD | PMID:25629700 | Nr2c2ap | Rat | folic acid | multiple interactions | ISO | Nr2c2ap (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of NR2C2AP mRNA | CTD | PMID:22206623 | Nr2c2ap | Rat | methyl methanesulfonate | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of NR2C2AP mRNA | CTD | PMID:23649840 | Nr2c2ap | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of NR2C2AP mRNA | CTD | PMID:24136188 | Nr2c2ap | Rat | paraquat | increases expression | EXP | | 6480464 | Paraquat results in increased expression of NR2C2AP mRNA | CTD | PMID:32680482 | Nr2c2ap | Rat | perfluorononanoic acid | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | perfluoro-n-nonanoic acid results in increased expression of NR2C2AP mRNA | CTD | PMID:32588087 | Nr2c2ap | Rat | pirinixic acid | multiple interactions | ISO | Nr2c2ap (Mus musculus) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of NR2C2AP mRNA | CTD | PMID:19710929 | Nr2c2ap | Rat | potassium chromate | multiple interactions | ISO | NR2C2AP (Homo sapiens) | 6480464 | [potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of NR2C2AP mRNA | CTD | PMID:22079256 | Nr2c2ap | Rat | potassium chromate | decreases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | potassium chromate(VI) results in decreased expression of NR2C2AP mRNA | CTD | PMID:22079256 and PMID:22714537 | Nr2c2ap | Rat | rotenone | increases expression | EXP | | 6480464 | Rotenone results in increased expression of NR2C2AP mRNA | CTD | PMID:28374803 | Nr2c2ap | Rat | sodium arsenite | decreases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | sodium arsenite results in decreased expression of NR2C2AP mRNA | CTD | PMID:38568856 | Nr2c2ap | Rat | sunitinib | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Sunitinib results in increased expression of NR2C2AP mRNA | CTD | PMID:31533062 | Nr2c2ap | Rat | temozolomide | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Temozolomide results in increased expression of NR2C2AP mRNA | CTD | PMID:31758290 | Nr2c2ap | Rat | testosterone | multiple interactions | ISO | NR2C2AP (Homo sapiens) | 6480464 | [Testosterone co-treated with Calcitriol] results in decreased expression of NR2C2AP mRNA | CTD | PMID:21592394 | Nr2c2ap | Rat | testosterone | decreases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Testosterone results in decreased expression of NR2C2AP mRNA | CTD | PMID:21592394 | Nr2c2ap | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of NR2C2AP mRNA] | CTD | PMID:31150632 | Nr2c2ap | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of NR2C2AP mRNA | CTD | PMID:31150632 | Nr2c2ap | Rat | tetrachloromethane | increases expression | ISO | Nr2c2ap (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of NR2C2AP mRNA | CTD | PMID:27339419 and PMID:31919559 | Nr2c2ap | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of NR2C2AP mRNA | CTD | PMID:34492290 | Nr2c2ap | Rat | urethane | decreases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Urethane results in decreased expression of NR2C2AP mRNA | CTD | PMID:28818685 | Nr2c2ap | Rat | valproic acid | increases methylation | ISO | NR2C2AP (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of NR2C2AP gene | CTD | PMID:29154799 | Nr2c2ap | Rat | valproic acid | increases expression | ISO | NR2C2AP (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of NR2C2AP mRNA | CTD | PMID:23179753 | |