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Gene: MAN2B2 (mannosidase alpha class 2B member 2) Homo sapiens
Symbol: MAN2B2
Name: mannosidase alpha class 2B member 2
Description: Predicted to have alpha-mannosidase activity; carbohydrate binding activity; and metal ion binding activity. Predicted to be involved in oligosaccharide catabolic process. Localizes to extracellular exosome; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3-isobutyl-1-methyl-7H-xanthine; 5-aza-2'-deoxycytidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: core-specific lysosomal alpha-1,6-Mannosidase; epididymis-specific alpha-mannosidase; KIAA0935; mannosidase, alpha, class 2B, member 2
Mus musculus (house mouse) : Man2b2 (mannosidase 2, alpha B2)  MGI  Alliance
Rattus norvegicus (Norway rat) : Man2b2 (mannosidase, alpha, class 2B, member 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Man2b2 (mannosidase alpha class 2B member 2)
Pan paniscus (bonobo/pygmy chimpanzee) : MAN2B2 (mannosidase alpha class 2B member 2)
Canis lupus familiaris (dog) : MAN2B2 (mannosidase alpha class 2B member 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Man2b2 (mannosidase alpha class 2B member 2)
Sus scrofa (pig) : MAN2B2 (mannosidase alpha class 2B member 2)
Chlorocebus sabaeus (African green monkey) : MAN2B2 (mannosidase alpha class 2B member 2)
Heterocephalus glaber (naked mole-rat) : Man2b2 (mannosidase alpha class 2B member 2)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl46,575,189 - 6,623,362 (+)EnsemblGRCh38hg38GRCh38
GRCh3846,575,189 - 6,623,362 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3746,576,902 - 6,624,188 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3646,627,803 - 6,675,089 (+)NCBINCBI36hg18NCBI36
Build 3446,694,973 - 6,742,260NCBI
Celera46,478,589 - 6,525,854 (+)NCBI
Cytogenetic Map4p16.1NCBI
HuRef46,509,194 - 6,555,738 (+)NCBIHuRef
CHM1_146,575,419 - 6,622,515 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on MAN2B2
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1318845
Created: 2005-01-12
Species: Homo sapiens
Last Modified: 2020-07-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.