Nr2c2ap (nuclear receptor 2C2-associated protein) - Rat Genome Database
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Gene: Nr2c2ap (nuclear receptor 2C2-associated protein) Mus musculus
Analyze
Symbol: Nr2c2ap
Name: nuclear receptor 2C2-associated protein
RGD ID: 1622225
MGI Page MGI
Description: Predicted to localize to nucleoplasm. Orthologous to human NR2C2AP (nuclear receptor 2C2 associated protein); INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 4-hydroxyphenyl retinamide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310073E15Rik; MGC103332; TR4 orphan receptor-associated 16 kDa protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,583,977 - 70,586,402 (+)NCBIGRCm39mm39
GRCm38870,131,327 - 70,133,752 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,131,333 - 70,133,749 (+)EnsemblGRCm38mm10GRCm38
MGSCv37872,655,232 - 72,657,647 (+)NCBIGRCm37mm9NCBIm37
MGSCv36873,060,322 - 73,062,741 (+)NCBImm8
Celera872,686,772 - 72,689,185 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component
nucleoplasm  (ISO)
nucleus  (IEA)

Molecular Function

References

Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:14610273   PMID:15782199   PMID:16141072   PMID:16141073   PMID:18799693  
PMID:21873635  


Genomics

Comparative Map Data
Nr2c2ap
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39870,583,977 - 70,586,402 (+)NCBIGRCm39mm39
GRCm38870,131,327 - 70,133,752 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl870,131,333 - 70,133,749 (+)EnsemblGRCm38mm10GRCm38
MGSCv37872,655,232 - 72,657,647 (+)NCBIGRCm37mm9NCBIm37
MGSCv36873,060,322 - 73,062,741 (+)NCBImm8
Celera872,686,772 - 72,689,185 (+)NCBICelera
Cytogenetic Map8B3.3NCBI
NR2C2AP
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1919,201,416 - 19,203,424 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl1919,201,409 - 19,203,414 (-)EnsemblGRCh38hg38GRCh38
GRCh381919,201,409 - 19,203,414 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371919,312,223 - 19,314,238 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361919,173,224 - 19,175,238 (-)NCBINCBI36hg18NCBI36
Celera1919,217,020 - 19,219,034 (-)NCBI
Cytogenetic Map19p13.11NCBI
HuRef1918,875,988 - 18,878,002 (-)NCBIHuRef
CHM1_11919,312,729 - 19,314,749 (-)NCBICHM1_1
Nr2c2ap
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01621,036,648 - 21,039,481 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1621,036,646 - 21,038,844 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01620,886,519 - 20,889,368 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41619,771,849 - 19,774,045 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1619,477,049 - 19,479,245 (-)NCBICelera
Cytogenetic Map16p14NCBI
Nr2c2ap
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555242,618,957 - 2,635,982 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049555242,634,302 - 2,635,982 (+)NCBIChiLan1.0ChiLan1.0
NR2C2AP
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11919,640,163 - 19,642,179 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1919,640,163 - 19,642,179 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01918,639,380 - 18,641,725 (-)NCBIMhudiblu_PPA_v0panPan3
NR2C2AP
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl2043,976,665 - 43,977,823 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.12043,976,373 - 43,978,410 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Nr2c2ap
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365962,223,907 - 2,225,434 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
NR2C2AP
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl258,675,990 - 58,678,026 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1258,675,987 - 58,678,025 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
LOC103234206
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1617,669,412 - 17,671,640 (-)NCBI
ChlSab1.1 Ensembl617,669,933 - 17,671,398 (-)Ensembl
Nr2c2ap
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249082,094,783 - 2,097,088 (-)NCBI


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1558870Eae36_mexperimental allergic encephalomyelitis susceptibility 36 (mouse)Not determined81472316071045600Mouse
1357811Orq3_movulation rate QTL 3 (mouse)Not determined83201654471287993Mouse
4141437W10q14_mweight 10 weeks QTL 14 (mouse)Not determined3201654471287993Mouse
4141172W6q9_mweight 6 weeks QTL 9 (mouse)Not determined3201654471287993Mouse
4140966Egq12_mearly growth QTL 12 (mouse)Not determined3201654471287993Mouse
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301544Iba3_minduction of brown adipocytes 3 (mouse)Not determined84429488078295025Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:266
Count of miRNA genes:220
Interacting mature miRNAs:244
Transcripts:ENSMUST00000095273
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000095273   ⟹   ENSMUSP00000092907
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,131,347 - 70,133,739 (+)Ensembl
RefSeq Acc Id: ENSMUST00000211898   ⟹   ENSMUSP00000148493
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,131,333 - 70,133,748 (+)Ensembl
RefSeq Acc Id: ENSMUST00000212851
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl870,131,347 - 70,133,749 (+)Ensembl
RefSeq Acc Id: NM_001025586   ⟹   NP_001020757
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,583,977 - 70,586,402 (+)NCBI
GRCm38870,131,327 - 70,133,752 (+)NCBI
MGSCv37872,655,232 - 72,657,647 (+)RGD
Celera872,686,766 - 72,689,185 (+)NCBI
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001025587   ⟹   NP_001020758
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,583,977 - 70,586,402 (+)NCBI
GRCm38870,131,327 - 70,133,752 (+)NCBI
MGSCv37872,655,232 - 72,657,647 (+)RGD
Celera872,686,766 - 72,689,185 (+)NCBI
cM Map8 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_104434
RefSeq Status: VALIDATED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,583,977 - 70,586,402 (+)NCBI
GRCm38870,131,327 - 70,133,752 (+)NCBI
Celera872,686,766 - 72,689,185 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006509777   ⟹   XP_006509840
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39870,584,163 - 70,586,402 (+)NCBI
GRCm38870,131,513 - 70,133,752 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_001020757   ⟸   NM_001025586
- Peptide Label: isoform 1
- UniProtKB: Q3TV70 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001020758   ⟸   NM_001025587
- Peptide Label: isoform 2
- UniProtKB: Q3TV70 (UniProtKB/Swiss-Prot),   Q569V8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006509840   ⟸   XM_006509777
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSMUSP00000148493   ⟸   ENSMUST00000211898
RefSeq Acc Id: ENSMUSP00000092907   ⟸   ENSMUST00000095273

Promoters
RGD ID:8667275
Promoter ID:EPDNEW_M11669
Type:multiple initiation site
Name:Nr2c2ap_1
Description:Mus musculus nuclear receptor 2C2-associated protein , transcriptvariant 3, non-coding RNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38870,131,358 - 70,131,418EPDNEW
RGD ID:6842507
Promoter ID:MM_KWN:54662
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:NM_001025586,   NM_001025587,   UC009LYV.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,654,331 - 72,655,722 (+)MPROMDB
RGD ID:6848899
Promoter ID:MM_TRO:9540
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:MEF_B6
Transcripts:MTR015037.8.1174.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36872,655,626 - 72,656,126 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1922942 AgrOrtholog
Ensembl Genes ENSMUSG00000071078 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000092907 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000148493 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000095273 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000211898 ENTREZGENE, UniProtKB/TrEMBL
Gene3D-CATH 2.60.120.260 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro Galactose-bd-like_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NR2C2AP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:75692 UniProtKB/Swiss-Prot
MGD MGI:1922942 ENTREZGENE
NCBI Gene 75692 ENTREZGENE
PANTHER PTHR31535:SF1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Nr2c2ap PhenoGen
Superfamily-SCOP SSF49785 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.161167 ENTREZGENE
  Mm.390045 ENTREZGENE
UniProt A0A1D5RLT0_MOUSE UniProtKB/TrEMBL
  NR2CA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q569V8 ENTREZGENE, UniProtKB/TrEMBL