Phf8 (PHD finger protein 8) - Rat Genome Database

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Pathways
Gene: Phf8 (PHD finger protein 8) Rattus norvegicus
Analyze
Symbol: Phf8
Name: PHD finger protein 8
RGD ID: 1561065
Description: Predicted to enable several functions, including histone H3K4me3 reader activity; histone demethylase activity; and transition metal ion binding activity. Predicted to be involved in G1/S transition of mitotic cell cycle; chromatin remodeling; and positive regulation of macromolecule biosynthetic process. Predicted to be located in nucleolus. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Siderius type. Orthologous to human PHF8 (PHD finger protein 8); PARTICIPATES IN histone modification pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; acrylamide.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: histone lysine demethylase PHF8; hypothetical protein LOC317425; LOC102550078; LOC317425; RGD1561065; similar to mKIAA1111 protein; uncharacterized LOC102550078; uncharacterized protein LOC317425
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X23,967,126 - 24,066,473 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX23,967,556 - 24,066,471 (+)EnsemblGRCr8
mRatBN7.2X20,524,103 - 20,623,459 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX20,524,558 - 20,623,410 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX17,962,664 - 18,060,911 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X22,062,670 - 22,160,921 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X21,053,800 - 21,152,651 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X21,063,487 - 21,168,750 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX21,063,562 - 21,168,750 (+)Ensemblrn6Rnor6.0
Rnor_5.0X22,281,640 - 22,387,057 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X40,869,942 - 40,970,244 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX20,777,198 - 20,875,387 (+)NCBICelera
Cytogenetic MapXq12NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Systematic knockdown of epigenetic enzymes identifies a novel histone demethylase PHF8 overexpressed in prostate cancer with an impact on cell proliferation, migration and invasion. Bjorkman M, etal., Oncogene. 2012 Jul 19;31(29):3444-56. doi: 10.1038/onc.2011.512. Epub 2011 Nov 28.
2. Histone lysine methylation dynamics: establishment, regulation, and biological impact. Black JC, etal., Mol Cell. 2012 Nov 30;48(4):491-507. doi: 10.1016/j.molcel.2012.11.006.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
Additional References at PubMed
PMID:19843542   PMID:20023638   PMID:20208542   PMID:20346720   PMID:20622853   PMID:20622854   PMID:21029866  


Genomics

Comparative Map Data
Phf8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8X23,967,126 - 24,066,473 (+)NCBIGRCr8GRCr8GRCr8
GRCr8 EnsemblX23,967,556 - 24,066,471 (+)EnsemblGRCr8
mRatBN7.2X20,524,103 - 20,623,459 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 EnsemblX20,524,558 - 20,623,410 (+)EnsemblmRatBN7.2
UTH_Rnor_SHR_UtxX17,962,664 - 18,060,911 (+)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0X22,062,670 - 22,160,921 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0X21,053,800 - 21,152,651 (+)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0X21,063,487 - 21,168,750 (+)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblX21,063,562 - 21,168,750 (+)Ensemblrn6Rnor6.0
Rnor_5.0X22,281,640 - 22,387,057 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4X40,869,942 - 40,970,244 (+)NCBIRGSC_v3.4RGSC_v3.4rn4
CeleraX20,777,198 - 20,875,387 (+)NCBICelera
Cytogenetic MapXq12NCBI
PHF8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X53,936,680 - 54,048,936 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 EnsemblX53,936,676 - 54,048,958 (-)Ensemblhg38GRCh38
GRCh37X53,963,113 - 54,071,569 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X53,979,838 - 54,087,036 (-)NCBIBuild 36Build 36hg18NCBI36
Build 34X53,846,135 - 53,953,332NCBI
CeleraX57,794,656 - 57,902,802 (-)NCBICelera
Cytogenetic MapXp11.22NCBI
HuRefX51,017,153 - 51,124,050 (-)NCBIHuRef
CHM1_1X53,954,083 - 54,062,605 (-)NCBICHM1_1
T2T-CHM13v2.0X53,226,407 - 53,338,824 (-)NCBIT2T-CHM13v2.0
Phf8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39X150,303,621 - 150,416,855 (+)NCBIGRCm39GRCm39mm39
GRCm39 EnsemblX150,303,668 - 150,416,855 (+)EnsemblGRCm39 EnsemblGRCm39
GRCm38X151,520,641 - 151,633,859 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblX151,520,672 - 151,633,859 (+)Ensemblmm10GRCm38
MGSCv37X147,955,215 - 148,068,400 (+)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36X146,861,897 - 146,966,549 (+)NCBIMGSCv36mm8
CeleraX132,791,679 - 132,892,823 (-)NCBICelera
Cytogenetic MapXF3NCBI
cM MapX68.46NCBI
Phf8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554751,105,619 - 1,230,756 (-)Ensembl
ChiLan1.0NW_0049554751,105,619 - 1,230,758 (-)NCBIChiLan1.0ChiLan1.0
PHF8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2X55,327,026 - 55,435,822 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1X55,330,624 - 55,443,589 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0X46,144,815 - 46,250,594 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1X54,250,970 - 54,355,278 (-)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 EnsemblX54,250,970 - 54,355,913 (-)EnsemblpanPan2panpan1.1
PHF8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1X45,635,204 - 45,741,850 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblX45,571,840 - 46,081,994 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_TashaX37,095,737 - 37,202,320 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0X45,962,900 - 46,069,769 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 EnsemblX45,960,832 - 46,069,783 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1X45,454,705 - 45,561,287 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0X45,904,962 - 46,011,865 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0X45,972,344 - 46,078,926 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
Phf8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2X38,510,905 - 38,595,607 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936751850,237 - 934,586 (-)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_004936751850,630 - 935,382 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PHF8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblX46,648,168 - 46,759,239 (-)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1X46,648,164 - 46,761,192 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2X52,130,299 - 52,307,327 (-)NCBISscrofa10.2Sscrofa10.2susScr3
PHF8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1X50,058,687 - 50,172,827 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 EnsemblX50,058,273 - 50,172,086 (-)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_0236660864,010,981 - 4,117,007 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Phf8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249091,481,710 - 1,639,840 (-)NCBIHetGla 1.0HetGla 1.0hetGla2
Phf8
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1X12,621,543 - 12,683,751 (+)NCBIRrattus_CSIRO_v1

Variants

.
Variants in Phf8
487 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:539
Count of miRNA genes:251
Interacting mature miRNAs:300
Transcripts:ENSRNOT00000045708
Prediction methods:Microtar, Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
70165Bp64Blood pressure QTL 645.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)X400149344939387Rat
731181Uae27Urinary albumin excretion QTL 272.70.0059urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)X197044046970440Rat
631666Iddm5Insulin dependent diabetes mellitus QTL 5blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)X811148653111486Rat
634325Bw13Body weight QTL 130body mass (VT:0001259)body weight (CMO:0000012)X400149324470521Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 165 91 90 59 92 59 6 356 192 11 144 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001108253 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434155 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001434159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006256796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008773119 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017602072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099807 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099808 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099813 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039099814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280064 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280065 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063280067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide CH474063 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ228348 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000021 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000045708   ⟹   ENSRNOP00000040672
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX23,967,560 - 24,066,471 (+)Ensembl
mRatBN7.2 EnsemblX20,524,558 - 20,623,410 (+)Ensembl
Rnor_6.0 EnsemblX21,063,562 - 21,168,750 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093422
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 EnsemblX23,967,556 - 24,066,470 (+)Ensembl
mRatBN7.2 EnsemblX20,524,558 - 20,623,410 (+)Ensembl
Rnor_6.0 EnsemblX21,063,651 - 21,160,680 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000093656
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 EnsemblX21,094,640 - 21,095,485 (+)Ensembl
RefSeq Acc Id: NM_001108253   ⟹   NP_001101723
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,578 - 24,066,424 (+)NCBI
mRatBN7.2X20,524,558 - 20,623,410 (+)NCBI
Rnor_6.0X21,063,545 - 21,168,701 (+)NCBI
Rnor_5.0X22,281,640 - 22,387,057 (-)NCBI
RGSC_v3.4X40,869,942 - 40,970,244 (+)RGD
CeleraX20,777,198 - 20,875,387 (+)RGD
Sequence:
RefSeq Acc Id: XM_006256792   ⟹   XP_006256854
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,127 - 24,066,473 (+)NCBI
mRatBN7.2X20,524,502 - 20,623,459 (+)NCBI
Rnor_6.0X21,063,487 - 21,168,750 (+)NCBI
Rnor_5.0X22,281,640 - 22,387,057 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008773119   ⟹   XP_008771341
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,968,497 - 24,066,473 (+)NCBI
mRatBN7.2X20,525,477 - 20,623,459 (+)NCBI
Rnor_6.0X21,064,527 - 21,168,750 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017602072   ⟹   XP_017457561
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,511 - 24,066,473 (+)NCBI
mRatBN7.2X20,524,502 - 20,623,459 (+)NCBI
Rnor_6.0X21,063,487 - 21,168,750 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039099807   ⟹   XP_038955735
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,511 - 24,066,473 (+)NCBI
mRatBN7.2X20,524,502 - 20,623,459 (+)NCBI
RefSeq Acc Id: XM_039099808   ⟹   XP_038955736
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,511 - 24,066,473 (+)NCBI
mRatBN7.2X20,524,502 - 20,623,459 (+)NCBI
RefSeq Acc Id: XM_039099810   ⟹   XP_038955738
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,511 - 24,066,473 (+)NCBI
mRatBN7.2X20,524,503 - 20,623,459 (+)NCBI
RefSeq Acc Id: XM_039099813   ⟹   XP_038955741
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X24,006,139 - 24,066,473 (+)NCBI
mRatBN7.2X20,562,184 - 20,623,459 (+)NCBI
RefSeq Acc Id: XM_039099814   ⟹   XP_038955742
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X24,006,160 - 24,066,473 (+)NCBI
mRatBN7.2X20,563,143 - 20,623,459 (+)NCBI
RefSeq Acc Id: XM_063280064   ⟹   XP_063136134
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,511 - 24,066,473 (+)NCBI
RefSeq Acc Id: XM_063280065   ⟹   XP_063136135
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,126 - 24,066,473 (+)NCBI
RefSeq Acc Id: XM_063280066   ⟹   XP_063136136
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,509 - 24,066,473 (+)NCBI
RefSeq Acc Id: XM_063280067   ⟹   XP_063136137
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8X23,967,508 - 24,066,473 (+)NCBI
RefSeq Acc Id: NP_001101723   ⟸   NM_001108253
- UniProtKB: D4AD31 (UniProtKB/TrEMBL),   A6KLA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006256854   ⟸   XM_006256792
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_008771341   ⟸   XM_008773119
- Peptide Label: isoform X1
- UniProtKB: D4AD31 (UniProtKB/TrEMBL),   A6KLA6 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017457561   ⟸   XM_017602072
- Peptide Label: isoform X1
- UniProtKB: D4AD31 (UniProtKB/TrEMBL),   A6KLA6 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000040672   ⟸   ENSRNOT00000045708
RefSeq Acc Id: XP_038955736   ⟸   XM_039099808
- Peptide Label: isoform X1
- UniProtKB: D4AD31 (UniProtKB/TrEMBL),   A6KLA6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955735   ⟸   XM_039099807
- Peptide Label: isoform X1
RefSeq Acc Id: XP_038955738   ⟸   XM_039099810
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AC06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038955741   ⟸   XM_039099813
- Peptide Label: isoform X5
RefSeq Acc Id: XP_038955742   ⟸   XM_039099814
- Peptide Label: isoform X6
RefSeq Acc Id: XP_063136135   ⟸   XM_063280065
- Peptide Label: isoform X2
- UniProtKB: A0A8I6AC06 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063136137   ⟸   XM_063280067
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063136136   ⟸   XM_063280066
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063136134   ⟸   XM_063280064
- Peptide Label: isoform X2
Protein Domains
JmjC   PHD-type

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D4AD31-F1-model_v2 AlphaFold D4AD31 1-1023 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13701767
Promoter ID:EPDNEW_R12291
Type:multiple initiation site
Name:Phf8_1
Description:PHD finger protein 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0X21,063,545 - 21,063,605EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561065 AgrOrtholog
BioCyc Gene G2FUF-2769 BioCyc
Ensembl Genes ENSRNOG00000002708 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000045708 ENTREZGENE
  ENSRNOT00000045708.7 UniProtKB/TrEMBL
  ENSRNOT00000093422 ENTREZGENE
  ENSRNOT00000093422.3 UniProtKB/TrEMBL
Gene3D-CATH 1.20.58.1360 UniProtKB/TrEMBL
  Cupin UniProtKB/TrEMBL
InterPro JHD UniProtKB/TrEMBL
  JHDM1_Histone_Demethylase UniProtKB/TrEMBL
  JmjC_dom UniProtKB/TrEMBL
  Zinc_finger_PHD-type_CS UniProtKB/TrEMBL
  Znf_FYVE_PHD UniProtKB/TrEMBL
  Znf_PHD UniProtKB/TrEMBL
  Znf_PHD-finger UniProtKB/TrEMBL
KEGG Report rno:317425 UniProtKB/TrEMBL
NCBI Gene 317425 ENTREZGENE
PANTHER PHD/F-BOX CONTAINING PROTEIN UniProtKB/TrEMBL
Pfam JHD UniProtKB/TrEMBL
  JmjC UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
PhenoGen Phf8 PhenoGen
PROSITE JMJC UniProtKB/TrEMBL
  ZF_PHD_1 UniProtKB/TrEMBL
  ZF_PHD_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002708 RatGTEx
SMART JmjC UniProtKB/TrEMBL
  PHD UniProtKB/TrEMBL
Superfamily-SCOP Clavaminate synthase-like UniProtKB/TrEMBL
  FYVE_PHD_ZnF UniProtKB/TrEMBL
UniProt A0A8I6AC06 ENTREZGENE, UniProtKB/TrEMBL
  A6KLA6 ENTREZGENE, UniProtKB/TrEMBL
  D4AD31 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2021-03-09 Phf8  PHD finger protein 8  LOC102550078  uncharacterized LOC102550078  Data merged from RGD:7608019 737654 PROVISIONAL
2013-12-18 LOC102550078  uncharacterized LOC102550078      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-10-11 Phf8  PHD finger protein 8  RGD1561065  similar to mKIAA1111 protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-04-30 RGD1561065  similar to mKIAA1111 protein   RGD1561065_predicted  similar to mKIAA1111 protein (predicted)  'predicted' is removed 2292626 APPROVED
2006-03-07 RGD1561065_predicted  similar to mKIAA1111 protein (predicted)  LOC317425  similar to mKIAA1111 protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC317425  similar to mKIAA1111 protein      Symbol and Name status set to provisional 70820 PROVISIONAL