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Gene: ADAMTS1 (ADAM metallopeptidase with thrombospondin type 1 motif 1) Sus scrofa

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Symbol:

ADAMTS1

Name:

ADAM metallopeptidase with thrombospondin type 1 motif 1

RGD ID:

14114444

Description:

ENCODES a protein that exhibits heparin binding (inferred); hydrolase activity (inferred); metal ion binding (inferred); INVOLVED IN cellular response to parathyroid hormone stimulus (ortholog); cellular response to prostaglandin E stimulus (ortholog); cellular response to vitamin D (ortholog); ASSOCIATED WITH Alzheimer's disease (ortholog); brain ischemia (ortholog); Breast Neoplasms (ortholog); FOUND IN extracellular matrix (ortholog)

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

A disintegrin and metalloproteinase with thrombospondin motifs 1; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 1

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

Sscrofa11.1 - Pig Sscrofa11.1 Assembly

Position:

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	190,276,430 - 190,286,214 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	190,277,175 - 190,285,957 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	200,127,201 - 200,135,962 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Alzheimer's disease (ISO)

brain ischemia (ISO)

Breast Neoplasms (ISO)

COVID-19 (ISO)

Endotoxemia (ISO)

epilepsy (ISO)

hepatocellular carcinoma (ISO)

Hypoglossal Nerve Injuries (ISO)

Kidney Reperfusion Injury (ISO)

lung non-small cell carcinoma (ISO)

myocardial infarction (ISO)

Neoplasm Invasiveness (ISO)

primary ovarian insufficiency (ISO)

transient cerebral ischemia (ISO)

ureteral obstruction (ISO)

urinary tract obstruction (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

cellular response to parathyroid hormone stimulus (ISO)

cellular response to prostaglandin E stimulus (ISO)

cellular response to vitamin D (ISO)

extracellular matrix organization (IBA,IEA)

heart trabecula formation (ISO)

kidney development (ISO)

negative regulation of angiogenesis (ISO)

ovulation from ovarian follicle (ISO)

positive regulation of G1/S transition of mitotic cell cycle (IEA)

positive regulation of neuron projection development (ISO)

positive regulation of vascular associated smooth muscle cell migration (IEA)

positive regulation of vascular associated smooth muscle cell proliferation (IEA)

proteolysis (IBA,IEA)

Cellular Component

basement membrane (IEA)

cytoplasmic vesicle (IEA)

extracellular matrix (IBA,IEA,ISO)

Molecular Function

heparin binding (IEA)

hydrolase activity (IEA)

metal ion binding (IEA)

metalloendopeptidase activity (IBA,IEA)

metallopeptidase activity (IEA)

peptidase activity (IEA)

protein binding (ISO)

zinc ion binding (IEA)

References

Additional References at PubMed

PMID:14681463	PMID:15231699	PMID:17145712	PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ADAMTS1
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	13	190,276,430 - 190,286,214 (-)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	13	190,277,175 - 190,285,957 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	13	200,127,201 - 200,135,962 (-)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ADAMTS1
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	21	26,835,755 - 26,845,409 (-)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	21	26,835,755 - 26,845,409 (-)	Ensembl			hg38	GRCh38
GRCh37	21	28,208,074 - 28,217,728 (-)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	21	27,130,477 - 27,139,599 (-)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	21	27,130,478 - 27,139,599	NCBI
Celera	21	13,391,944 - 13,401,066 (-)	NCBI		Celera
Cytogenetic Map	21	q21.3	NCBI
HuRef	21	13,613,149 - 13,622,273 (-)	NCBI		HuRef
CHM1_1	21	27,770,054 - 27,779,178 (-)	NCBI		CHM1_1
T2T-CHM13v2.0	21	25,193,845 - 25,203,500 (-)	NCBI		T2T-CHM13v2.0

Adamts1
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	16	85,590,715 - 85,600,001 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	16	85,590,715 - 85,600,001 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	16	85,793,827 - 85,803,113 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	16	85,793,827 - 85,803,113 (-)	Ensembl			mm10	GRCm38
MGSCv37	16	85,794,072 - 85,803,360 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	16	85,683,023 - 85,692,295 (-)	NCBI		MGSCv36	mm8
Celera	16	86,012,366 - 86,021,639 (-)	NCBI		Celera
Cytogenetic Map	16	C3.3	NCBI
cM Map	16	48.2	NCBI

Adamts1
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	11	38,418,565 - 38,427,384 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	11	38,418,101 - 38,427,390 (-)	Ensembl				GRCr8
mRatBN7.2	11	24,932,227 - 24,941,068 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	11	24,931,761 - 24,941,103 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	11	33,624,075 - 33,632,896 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	11	26,324,337 - 26,333,158 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	11	25,513,220 - 25,522,042 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Dahl_SR_JrHsd	11	40,334,808 - 40,343,612 (-)	NCBI		Dahl_SR_JrHsd
Lyon_Normotensive	11	38,632,349 - 38,641,170 (-)	NCBI		Lyon_Normotensive
Lyon_Hypertensive	11	39,569,018 - 39,577,822 (-)	NCBI		Lyon_Hypertensive
F344_StmMcwi	11	38,279,290 - 38,288,110 (-)	NCBI		F344_StmMcwi
Rnor_6.0	11	25,342,119 - 25,350,938 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	11	25,342,126 - 25,350,974 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	11	28,966,006 - 28,974,872 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	11	25,434,262 - 25,443,144 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	11	24,733,382 - 24,742,203 (-)	NCBI		Celera
RGSC_v3.1	11	25,433,799 - 25,443,150 (-)	NCBI
Cytogenetic Map	11	q11	NCBI

Adamts1
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955407	26,524,130 - 26,533,038 (-)	Ensembl
ChiLan1.0	NW_004955407	26,524,487 - 26,533,038 (-)	NCBI	ChiLan1.0	ChiLan1.0

ADAMTS1
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	22	23,020,036 - 23,030,193 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	21	17,883,284 - 17,891,842 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	21	13,270,668 - 13,279,217 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	21	26,656,370 - 26,665,485 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	21	26,656,370 - 26,665,485 (-)	Ensembl			panPan2	panpan1.1

ADAMTS1
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	31	22,169,821 - 22,178,879 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	31	22,170,381 - 22,178,945 (-)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	31	22,164,233 - 22,172,787 (-)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	31	22,267,999 - 22,276,520 (-)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	31	22,268,005 - 22,276,627 (-)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	31	22,240,472 - 22,248,981 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	31	22,246,052 - 22,254,554 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	31	22,720,934 - 22,729,448 (-)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

Adamts1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404971	22,713,285 - 22,721,753 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936640	959,417 - 968,842 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936640	959,405 - 967,305 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ADAMTS1
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	2	65,376,288 - 65,385,398 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	2	65,376,310 - 65,385,918 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666071	8,023,555 - 8,032,659 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Adamts1
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624745	14,802,371 - 14,811,203 (-)	Ensembl		HetGla_female_1.0 Ensembl	hetGla2	HetGla_female_1.0 Ensembl
HetGla 1.0	NW_004624745	14,802,703 - 14,811,568 (-)	NCBI	HetGla 1.0	HetGla 1.0	hetGla2

Variants

Variants in ADAMTS1
300 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	hemolymphoid system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
10	4	23	3	2	5	14	12	23	3	6	3

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001144843	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AB527056	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AEMK02000091	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK235174	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AK395318	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CU469332	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	DQ177331	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FP476141	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	GFLN01073803	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSSSCT00000013158 ⟹ ENSSSCP00000012808

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	13	190,276,430 - 190,286,214 (-)	Ensembl

Ensembl Acc Id:

ENSSSCT00000085444 ⟹ ENSSSCP00000070057

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1 Ensembl	13	190,276,430 - 190,286,214 (-)	Ensembl

RefSeq Acc Id:

NM_001144843 ⟹ NP_001138315

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Pig Assembly	Chr	Position (strand)	Source
Sscrofa11.1	13	190,277,175 - 190,285,957 (-)	NCBI

Sequence:

show sequence

GCAGCGTCTCCTCTTTAGTGACTCAGGGAGCCCTATCCGCGACCGGCTCCGCGCGCACTTTTAA
AGAATCATAGTAATTAACTTTAACAATCCTGAGCCTGACCAGCGCGAGGCTCTGTGCTCCGGGC
CGGAACAATAGCCCCTTCTTTGAGCGTGCGGCGGCGCGCGGTGCCTCCCGGGGCTCTGGTGCAG
CAAGCGGTCCTCGCAGGGTTCCGAAGGCGCACCGCAGGAGGCGACATGGGGAACACGGCGCGAC
GGTCTTGGGGCTCGCAGTCTGCGCCCACGCTGCTGCTGCTCACCGCGGCCACAACGCTGCTAGT
CTTGCAGGGCGCGCACGGGCGCCCAGTTGAGGAGGATGAGGAGCTGGTGCTGCCGGCATTGGAG
CGCGACCTGGCACACGGGACCGCGCACCTCCTCCTGGACGCCTTCGGCAGCCAGCTGCGCCTGG
AGCTGCAGCCGGATCGTGGCTTCCTAGCACCCGGTTTCACGCTTCAGACTGTAGGACGAAGACC
CGGACCCAACGCGTCGCATTCTGATCCAGCCGGCGATTTGGCGCACTGCTTCTACTCCGGCACG
GTGAACCGCGACCCCAGTTCCGCCGCTGCTCTTAGCCTCTGCGAGGGCGTGCGCGGTGCCTTCT
ACCTGCAGGGTGAGGAGTACTTCATCCAGCCCGCGCCCGCCGCCGCCGCAGTGGGCCTCGCCCC
CGCCGCCGCCGCCGGGGAGGAGCCGCTCGCGCGGCCCCAATTCCATCTCCTGCGGCGGAGGCGG
CGGGGAGGCGGCGGCGCCAAGTGCGGGGTCCTGGACGACGAGACCCAGCTCGCTAAGGACGCGG
GGTCGGAGGGCGAGGACGCCGCGGCGCAGTGGCCGCCGCAGAACTGGGAGCCACAGCGCGCTGG
ACAGTCAACAGGAACTGGAAGCCTGAGAAAGAAGCGATTTGTGTCCAGCCCCCGCTATGTGGAA
ACCATGCTTGTGGCCGACCAGTCCATGGCAGAGTTCCACGGCAGTGGTCTAAAGCATTACCTTC
TCACCTTGTTCTCGGTGGCAGCCCGGTTATACAAACACCCCAGCATTCGGGATTCAGTTAGCCT
GGTGGTGGTGAAGATCCTGGTCATCTACGAGGAACAGAAGGGGCCAGAAATCACCTCCAACGCT
GCCCTCACGCTTCGGAACTTCTGCAACTGGCAAAAGCAGCACAACCCGCCCAGTGACCGGGACG
CAGAGCACTACGACACTGCAATTCTTTTTACCAGACAGGACCTGTGTGGGGCCCAGACGTGTGA
TACTCTTGGGATGGCGGATGTTGGAACTGTGTGTGATCCCAGTAGAAGCTGCTCTGTTATAGAA
GATGATGGCTTACAAGCTGCCTTCACCACAGCCCATGAATTAGGCCATGTGTTTAACATGCCTC
ATGATGATGCCGAGCAATGTGCAAGCCTGAATGGTGTCAACCGGGATTCCCACATGATGGCGTC
AATGCTTTCCAATCTGGACCGCAGCCAGCCCTGGTCTCCCTGCAGCGCCTACATGATTACGTCA
TTTCTGGATAACGGTCACGGAGAATGCTTGATGGACAAGCCCCAGAGCCCCATACAGCTCCCCT
CTGACCTCCCCGGGACCTTGTATGATGCCAACCGGCAGTGCCAGTTTACGTTTGGGGAGGAGTC
CAAACACTGCCCTGACCCAGCCAGCACTTGCACGACCCTCTGGTGCACGGGCACCTCAGGTGGA
TTGCTGGTGTGCCAAACCAAACACTTCCCCTGGGCTGACGGCACCAGCTGTGGAGAAGGGAAAT
GGTGTGTCAACGGCAAGTGCGTGAACAAGACCGACAAGAAGCATTTTGATACTCCTGTTCATGG
AAGCTGGGGGCCGTGGGGTCCCTGGGGAGATTGTTCCAGAACGTGTGGTGGAGGAGTTCAGTAC
ACCATGAGGGAGTGTGACAACCCAGTCCCCAAGAACGGAGGGAAGTACTGCGAGGGCAAGCGCG
TGCGCTACAGGTCCTGCAACATCGAGGACTGTCCGGAAAATAATGGAAAAACCTTTAGAGAGGA
ACAGTGTGAGGCACACAATGAATTCTCCAAAGCTTCCTTTGGCAGTGGGCCACCTGTGGAGTGG
ACACCCAAGTACGCTGGAGTCTCACCCAAGGACAGGTGCAAGCTCATCTGTCAGGCCAAAGGCA
TTGGCTACTTCTTCGTTCTGCAGCCCAAGGTGGTAGATGGTACTCCTTGTAGCCCAGATTCCAC
CTCTGTCTGCGTGCAAGGACAGTGTGTAAAGGCTGGTTGTGATCGCATCATAGATTCCAAAAAG
AAGTTCGATAAATGTGGCATTTGTGGAGGAAATGGATCTACATGCAAGAAGATATCAGGATCAG
TTACGAGTGCAAAACCTGGCTATCATGATATCGTCACAATTCCAACCGGAGCCACCAACATTGA
AGTGAAACAGCGAAATCAGAGGGGTTCCAGAAATAATGGAAGCTTCCTTGCCATCAAAGCTGCC
GATGGCACATACATCCTGAATGGCGACTTCACTTTGTCCACTTTAGAGCAAGACATCACATACA
AAGGTAGTGTCTTGAGATACAGCGGCTCCTCCGCAGCGCTGGAAAGAATTCGAAGCTTTAGCCC
CCTCAAGGAGCCCTTAACCATCCAAGTCCTGACGGTGGGCAATGCCCTTCGACCAAAAATTAAG
TACACTTATTTTGTGAAGAAGAAGAAGGAATCTTTCAATGCCATCCCTACTTTCTCAGAGTGGG
TCATTGAAGAGTGGGGCGAGTGTTCCAAGACATGCGGACTAGGTGTGCAGAGAAGGCTGGTGGA
GTGCCGAGACATCAATGGGCAGCCTGCTTCCGAGTGTGCCAAGGAAGTGAAGCCAGCCAGCACC
AGACCTTGCGCGGACCTGCCATGCCCACATTGGCAGCTGGGGGACTGGTCGCCATGTTCCAAGA
CTTGCGGGAAGGGTTACAAAAAGAGAACCTTGCAGTGTCTGTCCCATGATGGGGGGGTGTTGGC
GCATGAGAGCTGCGATCCTCTAAAGAAACCTAAACATTACATAGATTTCTGCACGATGGCAGAG
TGCAGTTAAGCAGGGGCTGTGTTGAGGGCAGAGGGCAGTGGGGAAGGGCTGATGCACTGAAATC
AAGAAGGCTGGAGGAATCCAGGGCACCTTGCCAGTGATCAGCGAGGTGTGGCGATGAGTTGCGA
GGTAGAGGTAGGTAGAAAAGAAGTTAGGTCATCAGAATTTCCTGCCAGTTACAAATTTGATAGG
GTAGTTCCTGAGGATTATTCGTATCTGACCAATGATAGAGCATGATAAAGCCCCAGGGCATTAT
TATTTCTTCTGTTACGTCTGTGACAAGTTTTTACGGAAATAGAAACAATTGTCAAAGTAACTAA
GAAATAAGGTAATCCTTGTTTCCTGGTACCGATGAAGTGCTTTGTATCATGGAGGTTGGGACAT
GAAAAGCAGGAGGAAGATGAGGTTTTGGGCTTAAGATAGGGCTTCCTTTACTTCGCTAAGGCTG
GAGTGAGAAAAGAGTCTGCATAGGATCTTTAACCAGCTCTGTTCATGGCTGCTGTGGTTTCAGA
GAATGTTCATGCCATCGCTTCTATTGAGAGCTAAGAATCCAAGATTGTCCAGCATGAGAAATGA
CTCACCTGACTCCATCCTTCCTTTCTTGTGTCATTATTGTGTCTTTATTTGTGAGCTCATTTTG
ATGAAGAAACAATTCTATGTATTTGTAAAACCGGCATTTCAGTCTACAAGGGGAAAAAAAAAAA
AAAAAGCAGTGATGTATCAGATGCTGTTAAAAGCTAGGGGAGGCCGGATGATCTGGGCCCCTCC
TACCTTTCTTTCCTCCTGATGTAAGCCTGCTTAAGGAATGTGGATGTGAAAACAAAACAAAGCA
GTTTGCATCTGAAGTCAGTAAGATCACACAAAAAGGATGTAATGCCAGAACAAGAATGGGGTGT
GTACAACAGGGTCCCCAGTGTTTGGGGACATTGAAGTCACTTG

hide sequence

Protein Sequences


Protein RefSeqs	NP_001138315	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	ABA54553	(Get FASTA)	NCBI Sequence Viewer
	BAI47589	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSSSCP00000012808
	ENSSSCP00000012808.5
	ENSSSCP00000070057.2
	ENSSSCP00015041672.1
	ENSSSCP00015041738.1

RefSeq Acc Id:	NP_001138315 ⟸ NM_001144843
- Peptide Label:	precursor
- UniProtKB:	Q2N1I7 (UniProtKB/TrEMBL), A0A8D0Q6K7 (UniProtKB/TrEMBL)
- Sequence:	show sequence MGNTARRSWGSQSAPTLLLLTAATTLLVLQGAHGRPVEEDEELVLPALERDLAHGTAHLLLDAF GSQLRLELQPDRGFLAPGFTLQTVGRRPGPNASHSDPAGDLAHCFYSGTVNRDPSSAAALSLCE GVRGAFYLQGEEYFIQPAPAAAAVGLAPAAAAGEEPLARPQFHLLRRRRRGGGGAKCGVLDDET QLAKDAGSEGEDAAAQWPPQNWEPQRAGQSTGTGSLRKKRFVSSPRYVETMLVADQSMAEFHGS GLKHYLLTLFSVAARLYKHPSIRDSVSLVVVKILVIYEEQKGPEITSNAALTLRNFCNWQKQHN PPSDRDAEHYDTAILFTRQDLCGAQTCDTLGMADVGTVCDPSRSCSVIEDDGLQAAFTTAHELG HVFNMPHDDAEQCASLNGVNRDSHMMASMLSNLDRSQPWSPCSAYMITSFLDNGHGECLMDKPQ SPIQLPSDLPGTLYDANRQCQFTFGEESKHCPDPASTCTTLWCTGTSGGLLVCQTKHFPWADGT SCGEGKWCVNGKCVNKTDKKHFDTPVHGSWGPWGPWGDCSRTCGGGVQYTMRECDNPVPKNGGK YCEGKRVRYRSCNIEDCPENNGKTFREEQCEAHNEFSKASFGSGPPVEWTPKYAGVSPKDRCKL ICQAKGIGYFFVLQPKVVDGTPCSPDSTSVCVQGQCVKAGCDRIIDSKKKFDKCGICGGNGSTC KKISGSVTSAKPGYHDIVTIPTGATNIEVKQRNQRGSRNNGSFLAIKAADGTYILNGDFTLSTL EQDITYKGSVLRYSGSSAALERIRSFSPLKEPLTIQVLTVGNALRPKIKYTYFVKKKKESFNAI PTFSEWVIEEWGECSKTCGLGVQRRLVECRDINGQPASECAKEVKPASTRPCADLPCPHWQLGD WSPCSKTCGKGYKKRTLQCLSHDGGVLAHESCDPLKKPKHYIDFCTMAECS hide sequence

Ensembl Acc Id:

ENSSSCP00000012808 ⟸ ENSSSCT00000013158

Ensembl Acc Id:

ENSSSCP00000070057 ⟸ ENSSSCT00000085444

Protein Domains

Peptidase M12B

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSSSCG00000012026	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
	ENSSSCG00015074767	UniProtKB/TrEMBL
Ensembl Transcript	ENSSSCT00000013158	ENTREZGENE
	ENSSSCT00000013158.5	UniProtKB/TrEMBL
	ENSSSCT00000085444.2	UniProtKB/TrEMBL
	ENSSSCT00015100675.1	UniProtKB/TrEMBL
	ENSSSCT00015100801.1	UniProtKB/TrEMBL
Gene3D-CATH	2.20.100.10	UniProtKB/TrEMBL
	2.60.120.830	UniProtKB/TrEMBL
	3.40.1620.60	UniProtKB/TrEMBL
	3.40.390.10	UniProtKB/TrEMBL
InterPro	ADAM_CR_2	UniProtKB/TrEMBL
	ADAM_Cys-rich	UniProtKB/TrEMBL
	ADAM_spacer1	UniProtKB/TrEMBL
	ADAMTS/ADAMTS-like	UniProtKB/TrEMBL
	ADAMTS_ADAMTS-like	UniProtKB/TrEMBL
	ADAMTS_CR_3	UniProtKB/TrEMBL
	MetalloPept_cat_dom_sf	UniProtKB/TrEMBL
	Pept_M12B_ADAM-TS1	UniProtKB/TrEMBL
	Peptidase_M12B	UniProtKB/TrEMBL
	Peptidase_M12B_N	UniProtKB/TrEMBL
	TSP1_rpt	UniProtKB/TrEMBL
	TSP1_rpt_sf	UniProtKB/TrEMBL
KEGG Report	ssc:497061	UniProtKB/TrEMBL
NCBI Gene	ADAMTS1	ENTREZGENE
PANTHER	A DISINTEGRIN AND METALLOPROTEINASE WITH THROMBOSPONDIN MOTIFS 1	UniProtKB/TrEMBL
	ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE	UniProtKB/TrEMBL
Pfam	ADAM_CR_2	UniProtKB/TrEMBL
	ADAM_CR_3	UniProtKB/TrEMBL
	ADAM_spacer1	UniProtKB/TrEMBL
	Pep_M12B_propep	UniProtKB/TrEMBL
	Reprolysin	UniProtKB/TrEMBL
	TSP1_ADAMTS	UniProtKB/TrEMBL
	TSP_1	UniProtKB/TrEMBL
PRINTS	ADAMTS1	UniProtKB/TrEMBL
	ADAMTSFAMILY	UniProtKB/TrEMBL
	TSP1REPEAT	UniProtKB/TrEMBL
PROSITE	ADAM_MEPRO	UniProtKB/TrEMBL
	TSP1	UniProtKB/TrEMBL
SMART	ACR	UniProtKB/TrEMBL
	TSP1	UniProtKB/TrEMBL
Superfamily-SCOP	Metalloproteases ('zincins'), catalytic domain	UniProtKB/TrEMBL
	SSF82895	UniProtKB/TrEMBL
UniProt	A0A5G2R7E9_PIG	UniProtKB/TrEMBL
	A0A8D0Q6K7	ENTREZGENE, UniProtKB/TrEMBL
	A0A8D0Q7Y4_PIG	UniProtKB/TrEMBL
	D0G0B5_PIG	UniProtKB/TrEMBL
	F1SHP1_PIG	UniProtKB/TrEMBL
	Q2N1I7	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:85072	ENTREZGENE

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar

Imported Disease Annotations - CTD

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