Akap3 (A-kinase anchoring protein 3) - Rat Genome Database

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Gene: Akap3 (A-kinase anchoring protein 3) Rattus norvegicus
Analyze
Symbol: Akap3
Name: A-kinase anchoring protein 3
RGD ID: 1359735
Description: Predicted to enable protein kinase A binding activity. Predicted to be involved in protein localization. Predicted to act upstream of or within blastocyst hatching and cell surface receptor protein serine/threonine kinase signaling pathway. Predicted to be located in acrosomal vesicle; sperm fibrous sheath; and sperm midpiece. Predicted to be active in cytoplasm and sperm principal piece. Human ortholog(s) of this gene implicated in spermatogenic failure 82. Orthologous to human AKAP3 (A-kinase anchoring protein 3); PARTICIPATES IN protein kinase A (PKA) signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,7-dihydropurine-6-thione; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: A kinase (PRKA) anchor protein 3; A-kinase anchor protein 3; MGC93915
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84161,374,198 - 161,400,062 (+)NCBIGRCr8
mRatBN7.24159,688,049 - 159,714,067 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4159,699,289 - 159,713,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4165,921,691 - 165,943,705 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04161,704,598 - 161,726,610 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04160,338,631 - 160,360,645 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04159,399,686 - 159,425,512 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4159,403,501 - 159,425,629 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04232,187,481 - 232,213,270 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44163,241,422 - 163,263,433 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14163,486,357 - 163,508,368 (+)NCBI
Celera4148,408,052 - 148,430,063 (+)NCBICelera
Cytogenetic Map4q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum. Brown PR, etal., Biol Reprod 2003 Jun;68(6):2241-8. Epub 2003 Jan 22.
2. A-kinase anchoring proteins: from protein complexes to physiology and disease. Carnegie GK, etal., IUBMB Life. 2009 Apr;61(4):394-406.
3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
4. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
5. GOA pipeline RGD automated data pipeline
6. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
7. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
8. Comprehensive gene review and curation RGD comprehensive gene curation
9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
10. Localized effects of cAMP mediated by distinct routes of protein kinase A. Tasken K and Aandahl EM, Physiol Rev. 2004 Jan;84(1):137-67.
Additional References at PubMed
PMID:10319321   PMID:11278869   PMID:15257753   PMID:16687649   PMID:21630459   PMID:27869233   PMID:30745215  


Genomics

Comparative Map Data
Akap3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84161,374,198 - 161,400,062 (+)NCBIGRCr8
mRatBN7.24159,688,049 - 159,714,067 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4159,699,289 - 159,713,903 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4165,921,691 - 165,943,705 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04161,704,598 - 161,726,610 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04160,338,631 - 160,360,645 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04159,399,686 - 159,425,512 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4159,403,501 - 159,425,629 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04232,187,481 - 232,213,270 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44163,241,422 - 163,263,433 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14163,486,357 - 163,508,368 (+)NCBI
Celera4148,408,052 - 148,430,063 (+)NCBICelera
Cytogenetic Map4q42NCBI
AKAP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38124,615,518 - 4,649,051 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl124,615,508 - 4,649,051 (-)EnsemblGRCh38hg38GRCh38
GRCh37124,724,684 - 4,758,217 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36124,594,937 - 4,624,604 (-)NCBINCBI36Build 36hg18NCBI36
Build 34124,594,937 - 4,624,604NCBI
Celera126,346,705 - 6,376,375 (-)NCBICelera
Cytogenetic Map12p13.32NCBI
HuRef124,581,367 - 4,614,936 (-)NCBIHuRef
CHM1_1124,724,286 - 4,757,854 (-)NCBICHM1_1
T2T-CHM13v2.0124,622,335 - 4,655,891 (-)NCBIT2T-CHM13v2.0
Akap3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396126,830,061 - 126,851,271 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6126,830,061 - 126,851,271 (+)EnsemblGRCm39 Ensembl
GRCm386126,853,098 - 126,874,308 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6126,853,098 - 126,874,308 (+)EnsemblGRCm38mm10GRCm38
MGSCv376126,803,116 - 126,824,326 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366126,818,792 - 126,839,927 (+)NCBIMGSCv36mm8
Celera6128,530,738 - 128,551,961 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map661.92NCBI
Akap3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554132,411,553 - 2,433,388 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554132,411,618 - 2,432,658 (-)NCBIChiLan1.0ChiLan1.0
AKAP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21010,164,081 - 10,197,632 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11210,160,846 - 10,194,390 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0124,733,095 - 4,766,596 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1124,655,004 - 4,687,239 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl124,655,004 - 4,677,651 (-)Ensemblpanpan1.1panPan2
AKAP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12740,217,313 - 40,255,934 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2740,218,035 - 40,250,954 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha276,426,472 - 6,464,871 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02740,572,575 - 40,610,992 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2740,573,311 - 40,606,005 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12740,461,445 - 40,500,078 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02740,486,631 - 40,525,033 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0275,837,047 - 5,875,453 (-)NCBIUU_Cfam_GSD_1.0
Akap3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404945104,389,579 - 104,412,804 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366064,771,180 - 4,794,902 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366064,771,158 - 4,794,666 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AKAP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl565,797,376 - 65,819,765 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1565,788,744 - 65,816,031 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2567,995,078 - 68,020,685 (+)NCBISscrofa10.2Sscrofa10.2susScr3
AKAP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1114,635,962 - 4,675,993 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl114,634,442 - 4,673,571 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660633,565,363 - 3,605,962 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Akap3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046248601,684,433 - 1,701,736 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046248601,684,474 - 1,701,307 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Akap3
84 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:59
Count of miRNA genes:48
Interacting mature miRNAs:57
Transcripts:ENSRNOT00000026775
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
6478754Anxrr43Anxiety related response QTL 430.14035locomotor behavior trait (VT:0001392)distance moved per unit of time into, out of or within a discrete space in an experimental apparatus (CMO:0001493)4144639524182687754Rat
724558Plsm2Polydactyly-luxate syndrome (PLS) morphotypes QTL 20.0003hindlimb integrity trait (VT:0010563)hind foot phalanges count (CMO:0001949)4132422778177422778Rat
1582237Kidm34Kidney mass QTL 3440.0001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)4148090542168069246Rat
6478693Anxrr32Anxiety related response QTL 320.00092locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4144639524182687754Rat
10755501Bp390Blood pressure QTL 3902.5arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)426775591168368347Rat
631683Bp116Blood pressure QTL 1160.0001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)4124303370169303370Rat
61451Ciaa4CIA Autoantibody QTL 43.1blood autoantibody amount (VT:0003725)calculated serum anti-rat type 2 collagen autoantibody titer (CMO:0001281)4126395976167139601Rat
1331738Bp209Blood pressure QTL 2092.979arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)4138503169179293946Rat
6478700Anxrr33Anxiety related response QTL 330.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
1298524Oia8Oil induced arthritis QTL 8joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
10053718Scort25Serum corticosterone level QTL 252.150.0097blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)4155561574182687754Rat
1549827Scl46Serum cholesterol level QTL 463.5blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)4132396220177396220Rat
634335Anxrr16Anxiety related response QTL 167.22locomotor behavior trait (VT:0001392)number of entries into a discrete space in an experimental apparatus (CMO:0000960)493308457167139447Rat
737821Hcar9Hepatocarcinoma resistance QTL 93.7liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)4109866907167139601Rat
7411558Bw133Body weight QTL 13313.840.001body mass (VT:0001259)body weight gain (CMO:0000420)4125590636170590636Rat
6478778Anxrr51Anxiety related response QTL 510.25384locomotor behavior trait (VT:0001392)measurement of voluntary locomotion into, out of or within a discrete space in an experimental apparatus (CMO:0000957)4124778595169778595Rat
10401796Kidm48Kidney mass QTL 48kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)4145568712182687754Rat
6478718Anxrr34Anxiety related response QTL 340.00896locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
631511Pia7Pristane induced arthritis QTL 74.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
1300109Rf13Renal function QTL 133.91renal blood flow trait (VT:2000006)absolute change in renal blood flow rate (CMO:0001168)4157710145182687754Rat
634347Hcar8Hepatocarcinoma resistance QTL 85.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)4123143783168143783Rat
1576316Ept5Estrogen-induced pituitary tumorigenesis QTL 53.8pituitary gland mass (VT:0010496)pituitary gland wet weight (CMO:0000853)483428419177635233Rat
2303623Vencon2Ventilatory control QTL 23.8respiration trait (VT:0001943)minute ventilation (CMO:0000132)4135204660180204660Rat
1578674Bmd12Bone mineral density QTL 123.8femur mineral mass (VT:0010011)compact volumetric bone mineral density (CMO:0001730)4135699135180699135Rat
1358202Gluco11Glucose level QTL 112.40.02adipocyte glucose uptake trait (VT:0004185)absolute change in adipocyte glucose uptake (CMO:0000873)485379421167139601Rat
61422Cia13Collagen induced arthritis QTL 134.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4132642577167139601Rat
634342Cia24Collagen induced arthritis QTL 244.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4146565735175236377Rat
737978Pia23Pristane induced arthritis QTL 235.3joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4131730738167139601Rat
61362Oia2Oil induced arthritis QTL 20.001joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)4138503169173369699Rat
2293659Bmd35Bone mineral density QTL 354.50.0001femur strength trait (VT:0010010)femoral neck ultimate force (CMO:0001703)4137755016181392681Rat
1331759Hrtrt13Heart rate QTL 133.54628heart pumping trait (VT:2000009)heart rate (CMO:0000002)4110275411168266883Rat
724535Cm18Cardiac mass QTL 182.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)4118856416163856416Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
6478748Anxrr42Anxiety related response QTL 420.28008locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4144639524182687754Rat
12798525Anxrr57Anxiety related response QTL 573.210.05locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)4147278504167139601Rat

Markers in Region
AI577267  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.24159,713,625 - 159,713,826 (+)MAPPERmRatBN7.2
Rnor_6.04159,425,234 - 159,425,434NCBIRnor6.0
Rnor_5.04232,187,559 - 232,187,759UniSTSRnor5.0
RGSC_v3.44163,263,155 - 163,263,355UniSTSRGSC3.4
Celera4148,429,785 - 148,429,985UniSTS
RH 3.4 Map41008.6UniSTS
Cytogenetic Map4q42UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
7 10 47 111 84 83 52 24 52 4 202 92 93 44 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001005557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006237492 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763288 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763289 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008763290 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592653 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017592654 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107683 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039107684 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286142 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286143 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286144 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286146 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063286147 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide BC081924 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473964 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000079225   ⟹   ENSRNOP00000071639
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl4159,410,799 - 159,425,629 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000086525   ⟹   ENSRNOP00000072217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl4159,699,289 - 159,713,903 (+)Ensembl
Rnor_6.0 Ensembl4159,403,501 - 159,425,511 (+)Ensembl
RefSeq Acc Id: NM_001005557   ⟹   NP_001005557
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,378,050 - 161,400,062 (+)NCBI
mRatBN7.24159,691,892 - 159,713,904 (+)NCBI
Rnor_6.04159,403,501 - 159,425,512 (+)NCBI
Rnor_5.04232,187,481 - 232,213,270 (-)NCBI
RGSC_v3.44163,241,422 - 163,263,433 (+)RGD
Celera4148,408,052 - 148,430,063 (+)RGD
Sequence:
RefSeq Acc Id: XM_006237488   ⟹   XP_006237550
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
mRatBN7.24159,691,827 - 159,714,067 (+)NCBI
Rnor_6.04159,403,418 - 159,425,512 (+)NCBI
Rnor_5.04232,187,481 - 232,213,270 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237489   ⟹   XP_006237551
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
mRatBN7.24159,691,827 - 159,714,067 (+)NCBI
Rnor_6.04159,403,417 - 159,425,512 (+)NCBI
Rnor_5.04232,187,481 - 232,213,270 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006237492   ⟹   XP_006237554
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,374,198 - 161,400,062 (+)NCBI
mRatBN7.24159,688,049 - 159,714,067 (+)NCBI
Rnor_6.04159,399,715 - 159,425,512 (+)NCBI
Rnor_5.04232,187,481 - 232,213,270 (-)NCBI
Sequence:
RefSeq Acc Id: XM_008763289   ⟹   XP_008761511
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,377,978 - 161,400,062 (+)NCBI
mRatBN7.24159,691,878 - 159,714,067 (+)NCBI
Rnor_6.04159,403,418 - 159,425,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008763290   ⟹   XP_008761512
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,374,222 - 161,400,062 (+)NCBI
mRatBN7.24159,688,127 - 159,714,067 (+)NCBI
Rnor_6.04159,399,686 - 159,425,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592653   ⟹   XP_017448142
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
mRatBN7.24159,691,838 - 159,714,067 (+)NCBI
Rnor_6.04159,403,418 - 159,425,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017592654   ⟹   XP_017448143
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
mRatBN7.24159,691,837 - 159,714,067 (+)NCBI
Rnor_6.04159,403,417 - 159,425,512 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039107683   ⟹   XP_038963611
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
mRatBN7.24159,691,838 - 159,714,067 (+)NCBI
RefSeq Acc Id: XM_039107684   ⟹   XP_038963612
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,374,198 - 161,400,062 (+)NCBI
mRatBN7.24159,688,049 - 159,714,067 (+)NCBI
RefSeq Acc Id: XM_063286142   ⟹   XP_063142212
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
RefSeq Acc Id: XM_063286143   ⟹   XP_063142213
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
RefSeq Acc Id: XM_063286144   ⟹   XP_063142214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
RefSeq Acc Id: XM_063286145   ⟹   XP_063142215
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
RefSeq Acc Id: XM_063286146   ⟹   XP_063142216
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
RefSeq Acc Id: XM_063286147   ⟹   XP_063142217
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr84161,375,833 - 161,400,062 (+)NCBI
RefSeq Acc Id: NP_001005557   ⟸   NM_001005557
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237554   ⟸   XM_006237492
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237550   ⟸   XM_006237488
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006237551   ⟸   XM_006237489
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761512   ⟸   XM_008763290
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008761511   ⟸   XM_008763289
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448143   ⟸   XM_017592654
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017448142   ⟸   XM_017592653
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000071639   ⟸   ENSRNOT00000079225
Ensembl Acc Id: ENSRNOP00000072217   ⟸   ENSRNOT00000086525
RefSeq Acc Id: XP_038963612   ⟸   XM_039107684
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_038963611   ⟸   XM_039107683
- Peptide Label: isoform X1
- UniProtKB: Q66HC6 (UniProtKB/TrEMBL),   A0A0G2K2E9 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142214   ⟸   XM_063286144
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2E9 (UniProtKB/TrEMBL),   Q66HC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142217   ⟸   XM_063286147
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2E9 (UniProtKB/TrEMBL),   Q66HC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142215   ⟸   XM_063286145
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2E9 (UniProtKB/TrEMBL),   Q66HC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142213   ⟸   XM_063286143
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2E9 (UniProtKB/TrEMBL),   Q66HC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142216   ⟸   XM_063286146
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2E9 (UniProtKB/TrEMBL),   Q66HC6 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_063142212   ⟸   XM_063286142
- Peptide Label: isoform X1
- UniProtKB: A0A0G2K2E9 (UniProtKB/TrEMBL),   Q66HC6 (UniProtKB/TrEMBL)
Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q66HC6-F1-model_v2 AlphaFold Q66HC6 1-858 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693417
Promoter ID:EPDNEW_R3942
Type:initiation region
Name:Akap3_1
Description:A-kinase anchoring protein 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.04159,403,488 - 159,403,548EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1359735 AgrOrtholog
BioCyc Gene G2FUF-42960 BioCyc
Ensembl Genes ENSRNOG00000059227 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000086525.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7112940 IMAGE-MGC_LOAD
InterPro AKAP_110 UniProtKB/TrEMBL
  AKAP_110_C UniProtKB/TrEMBL
  SPHK1-interactor_AKAP_110 UniProtKB/TrEMBL
KEGG Report rno:312720 UniProtKB/TrEMBL
MGC_CLONE MGC:93915 IMAGE-MGC_LOAD
NCBI Gene 312720 ENTREZGENE
PANTHER A-KINASE ANCHOR PROTEIN 3 UniProtKB/TrEMBL
  AKAP_110 UniProtKB/TrEMBL
Pfam AKAP_110 UniProtKB/TrEMBL
PhenoGen Akap3 PhenoGen
RatGTEx ENSRNOG00000059227 RatGTEx
SMART AKAP_110 UniProtKB/TrEMBL
UniProt A0A0G2K2E9 ENTREZGENE, UniProtKB/TrEMBL
  Q66HC6 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-25 Akap3  A-kinase anchoring protein 3  Akap3  A kinase (PRKA) anchor protein 3  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Akap3  A kinase (PRKA) anchor protein 3    A-kinase anchor protein 3  Name updated 1299863 APPROVED
2005-07-29 Akap3  A-kinase anchor protein 3      Symbol and Name status set to provisional 70820 PROVISIONAL