Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Morf4l2 | Rat | (+)-catechin | multiple interactions | ISO | MORF4L2 (Homo sapiens) | 6480464 | [Catechin co-treated with Grape Seed Proanthocyanidins] results in increased expression of MORF4L2 mRNA | CTD | PMID:24763279 | Morf4l2 | Rat | (+)-schisandrin B | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of MORF4L2 mRNA] | CTD | PMID:31150632 | Morf4l2 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of MORF4L2 mRNA | CTD | PMID:22206623 | Morf4l2 | Rat | 1,2-dimethylhydrazine | multiple interactions | ISO | Morf4l2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MORF4L2 mRNA | CTD | PMID:22206623 | Morf4l2 | Rat | 17alpha-ethynylestradiol | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Ethinyl Estradiol results in increased expression of MORF4L2 mRNA | CTD | PMID:17942748 | Morf4l2 | Rat | 17alpha-ethynylestradiol | affects expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Ethinyl Estradiol affects the expression of MORF4L2 mRNA | CTD | PMID:17555576 | Morf4l2 | Rat | 17alpha-ethynylestradiol | multiple interactions | ISO | Morf4l2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MORF4L2 mRNA | CTD | PMID:17942748 | Morf4l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of MORF4L2 mRNA | CTD | PMID:17942748 | Morf4l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of MORF4L2 mRNA | CTD | PMID:33387578 and PMID:34747641 | Morf4l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of MORF4L2 mRNA | CTD | PMID:21570461 and PMID:24680724 | Morf4l2 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | multiple interactions | ISO | Morf4l2 (Mus musculus) | 6480464 | [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of MORF4L2 mRNA | CTD | PMID:17942748 | Morf4l2 | Rat | 2,4-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 4-dinitrotoluene affects the expression of MORF4L2 mRNA | CTD | PMID:21346803 | Morf4l2 | Rat | 3-chloropropane-1,2-diol | increases expression | EXP | | 6480464 | alpha-Chlorohydrin results in increased expression of MORF4L2 mRNA | CTD | PMID:28522335 | Morf4l2 | Rat | 4,4'-diaminodiphenylmethane | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | 4 and 4'-diaminodiphenylmethane results in increased expression of MORF4L2 mRNA | CTD | PMID:18648102 | Morf4l2 | Rat | 4-hydroxyphenyl retinamide | decreases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Fenretinide results in decreased expression of MORF4L2 mRNA | CTD | PMID:28973697 | Morf4l2 | Rat | 5-azacytidine | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Azacitidine results in decreased expression of MORF4L2 mRNA | CTD | PMID:20823114 | Morf4l2 | Rat | 5-fluorouracil | decreases response to substance | ISO | MORF4L2 (Homo sapiens) | 6480464 | MORF4L2 mRNA results in decreased susceptibility to Fluorouracil | CTD | PMID:18593893 | Morf4l2 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of MORF4L2 mRNA | CTD | PMID:30047161 | Morf4l2 | Rat | acrylamide | increases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of MORF4L2 mRNA | CTD | PMID:32763439 | Morf4l2 | Rat | aldehydo-D-glucose | multiple interactions | EXP | | 6480464 | MORF4L2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] | CTD | PMID:21124846 | Morf4l2 | Rat | amitrole | decreases expression | EXP | | 6480464 | Amitrole results in decreased expression of MORF4L2 mRNA | CTD | PMID:38685447 | Morf4l2 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of MORF4L2 mRNA | CTD | PMID:30047161 | Morf4l2 | Rat | amphetamine | increases expression | EXP | | 6480464 | Amphetamine results in increased expression of MORF4L2 mRNA | CTD | PMID:30779732 | Morf4l2 | Rat | aristolochic acid A | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of MORF4L2 mRNA | CTD | PMID:33212167 | Morf4l2 | Rat | atrazine | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Atrazine results in increased expression of MORF4L2 mRNA | CTD | PMID:27655631 | Morf4l2 | Rat | azoxystrobin | increases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | azoxystrobin results in increased expression of MORF4L2 mRNA | CTD | PMID:33512557 | Morf4l2 | Rat | benzo[a]pyrene | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Benzo(a)pyrene results in increased expression of MORF4L2 mRNA | CTD | PMID:22228805 | Morf4l2 | Rat | benzo[a]pyrene | affects methylation | ISO | MORF4L2 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of MORF4L2 5' UTR and Benzo(a)pyrene affects the methylation of MORF4L2 promoter | CTD | PMID:27901495 | Morf4l2 | Rat | bisphenol A | affects expression | EXP | | 6480464 | bisphenol A affects the expression of MORF4L2 mRNA | CTD | PMID:25181051 | Morf4l2 | Rat | bisphenol A | multiple interactions | ISO | MORF4L2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of MORF4L2 gene | CTD | PMID:31601247 | Morf4l2 | Rat | bisphenol A | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | bisphenol A results in decreased expression of MORF4L2 mRNA | CTD | PMID:29275510 | Morf4l2 | Rat | bisphenol A | decreases methylation | ISO | Morf4l2 (Mus musculus) | 6480464 | bisphenol A results in decreased methylation of MORF4L2 promoter | CTD | PMID:27312807 | Morf4l2 | Rat | buspirone | decreases expression | EXP | | 6480464 | Buspirone results in decreased expression of MORF4L2 mRNA | CTD | PMID:24136188 | Morf4l2 | Rat | carbon nanotube | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Nanotubes more ... | CTD | PMID:25554681 and PMID:25620056 | Morf4l2 | Rat | chloropicrin | affects expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | chloropicrin affects the expression of MORF4L2 mRNA | CTD | PMID:26352163 | Morf4l2 | Rat | chloropicrin | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | chloropicrin results in decreased expression of MORF4L2 mRNA | CTD | PMID:28476498 | Morf4l2 | Rat | ciguatoxin CTX1B | affects expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Ciguatoxins affects the expression of MORF4L2 mRNA | CTD | PMID:18353800 | Morf4l2 | Rat | clofibrate | decreases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of MORF4L2 mRNA | CTD | PMID:17585979 and PMID:23811191 | Morf4l2 | Rat | clofibric acid | affects expression | EXP | | 6480464 | Clofibric Acid affects the expression of MORF4L2 mRNA | CTD | PMID:17602206 | Morf4l2 | Rat | copper atom | multiple interactions | ISO | MORF4L2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of MORF4L2 mRNA | CTD | PMID:20971185 | Morf4l2 | Rat | copper(0) | multiple interactions | ISO | MORF4L2 (Homo sapiens) | 6480464 | [NSC 689534 binds to Copper] which results in increased expression of MORF4L2 mRNA | CTD | PMID:20971185 | Morf4l2 | Rat | coumestrol | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Coumestrol results in decreased expression of MORF4L2 mRNA | CTD | PMID:19167446 | Morf4l2 | Rat | cyclosporin A | increases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Cyclosporine results in increased expression of MORF4L2 mRNA | CTD | PMID:20106945 | Morf4l2 | Rat | D-glucose | multiple interactions | EXP | | 6480464 | MORF4L2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] | CTD | PMID:21124846 | Morf4l2 | Rat | Dibutyl phosphate | affects expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of MORF4L2 mRNA | CTD | PMID:37042841 | Morf4l2 | Rat | dibutyl phthalate | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Dibutyl Phthalate results in increased expression of MORF4L2 mRNA | CTD | PMID:21266533 | Morf4l2 | Rat | dicrotophos | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | dicrotophos results in decreased expression of MORF4L2 mRNA | CTD | PMID:28302478 | Morf4l2 | Rat | dioxygen | multiple interactions | EXP | | 6480464 | MORF4L2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] | CTD | PMID:21124846 | Morf4l2 | Rat | entinostat | increases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | entinostat results in increased expression of MORF4L2 mRNA | CTD | PMID:27188386 | Morf4l2 | Rat | ethanol | multiple interactions | ISO | Morf4l2 (Mus musculus) | 6480464 | Ethanol affects the expression of and affects the splicing of MORF4L2 mRNA | CTD | PMID:30319688 | Morf4l2 | Rat | ethanol | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Ethanol results in increased expression of MORF4L2 mRNA | CTD | PMID:30319688 | Morf4l2 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of MORF4L2 mRNA | CTD | PMID:24136188 | Morf4l2 | Rat | folic acid | multiple interactions | ISO | Morf4l2 (Mus musculus) | 6480464 | [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of MORF4L2 mRNA | CTD | PMID:22206623 | Morf4l2 | Rat | folpet | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | folpet results in increased expression of MORF4L2 mRNA | CTD | PMID:31558096 | Morf4l2 | Rat | formaldehyde | increases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Formaldehyde results in increased expression of MORF4L2 mRNA | CTD | PMID:20655997 | Morf4l2 | Rat | FR900359 | decreases phosphorylation | ISO | MORF4L2 (Homo sapiens) | 6480464 | FR900359 results in decreased phosphorylation of MORF4L2 protein | CTD | PMID:37730182 | Morf4l2 | Rat | fulvestrant | multiple interactions | ISO | MORF4L2 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of MORF4L2 gene | CTD | PMID:31601247 | Morf4l2 | Rat | furan | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | furan results in increased expression of MORF4L2 mRNA | CTD | PMID:24183702 | Morf4l2 | Rat | glafenine | increases expression | EXP | | 6480464 | Glafenine results in increased expression of MORF4L2 mRNA | CTD | PMID:24136188 | Morf4l2 | Rat | glucose | multiple interactions | EXP | | 6480464 | MORF4L2 protein results in decreased susceptibility to [Oxygen deficiency co-treated with Glucose deficiency] | CTD | PMID:21124846 | Morf4l2 | Rat | inulin | multiple interactions | ISO | Morf4l2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of MORF4L2 mRNA | CTD | PMID:36331819 | Morf4l2 | Rat | lead diacetate | decreases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | lead acetate results in decreased expression of MORF4L2 mRNA | CTD | PMID:21829687 | Morf4l2 | Rat | mercury atom | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Mercury results in decreased expression of MORF4L2 mRNA | CTD | PMID:16823088 | Morf4l2 | Rat | mercury(0) | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Mercury results in decreased expression of MORF4L2 mRNA | CTD | PMID:16823088 | Morf4l2 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of MORF4L2 mRNA | CTD | PMID:30047161 | Morf4l2 | Rat | methotrexate | affects expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Methotrexate affects the expression of MORF4L2 mRNA | CTD | PMID:18502557 | Morf4l2 | Rat | methylparaben | increases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | methylparaben results in increased expression of MORF4L2 mRNA | CTD | PMID:31745603 | Morf4l2 | Rat | nefazodone | increases expression | EXP | | 6480464 | nefazodone results in increased expression of MORF4L2 mRNA | CTD | PMID:24136188 | Morf4l2 | Rat | paracetamol | affects expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Acetaminophen affects the expression of MORF4L2 mRNA | CTD | PMID:17562736 | Morf4l2 | Rat | paracetamol | decreases expression | EXP | | 6480464 | Acetaminophen results in decreased expression of MORF4L2 mRNA | CTD | PMID:33387578 | Morf4l2 | Rat | paracetamol | increases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Acetaminophen results in increased expression of MORF4L2 mRNA | CTD | PMID:21420995 | Morf4l2 | Rat | perfluorooctane-1-sulfonic acid | multiple interactions | ISO | Morf4l2 (Mus musculus) | 6480464 | [perfluorooctane sulfonic acid co-treated with Inulin] results in decreased expression of MORF4L2 mRNA | CTD | PMID:36331819 | Morf4l2 | Rat | propiconazole | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | propiconazole results in increased expression of MORF4L2 mRNA | CTD | PMID:21278054 | Morf4l2 | Rat | resveratrol | multiple interactions | ISO | MORF4L2 (Homo sapiens) | 6480464 | [Plant Extracts co-treated with Resveratrol] results in increased expression of MORF4L2 mRNA | CTD | PMID:23557933 | Morf4l2 | Rat | rotenone | increases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Rotenone results in increased expression of MORF4L2 mRNA | CTD | PMID:33512557 | Morf4l2 | Rat | rotenone | decreases expression | EXP | | 6480464 | Rotenone results in decreased expression of MORF4L2 protein | CTD | PMID:35544339 | Morf4l2 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of MORF4L2 mRNA | CTD | PMID:30047161 | Morf4l2 | Rat | tamoxifen | affects expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Tamoxifen affects the expression of MORF4L2 mRNA | CTD | PMID:17555576 | Morf4l2 | Rat | tamoxifen | affects expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Tamoxifen affects the expression of MORF4L2 mRNA | CTD | PMID:14699072 | Morf4l2 | Rat | tetrachloromethane | multiple interactions | EXP | | 6480464 | schizandrin B inhibits the reaction [Carbon Tetrachloride results in increased expression of MORF4L2 mRNA] | CTD | PMID:31150632 | Morf4l2 | Rat | tetrachloromethane | increases expression | EXP | | 6480464 | Carbon Tetrachloride results in increased expression of MORF4L2 mRNA | CTD | PMID:31150632 | Morf4l2 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of MORF4L2 mRNA | CTD | PMID:34492290 | Morf4l2 | Rat | titanium dioxide | decreases methylation | ISO | Morf4l2 (Mus musculus) | 6480464 | titanium dioxide results in decreased methylation of MORF4L2 promoter | CTD | PMID:35295148 | Morf4l2 | Rat | trichloroethene | increases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Trichloroethylene results in increased expression of MORF4L2 mRNA | CTD | PMID:19448997 | Morf4l2 | Rat | triphenyl phosphate | affects expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of MORF4L2 mRNA | CTD | PMID:37042841 | Morf4l2 | Rat | valproic acid | affects expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Valproic Acid affects the expression of MORF4L2 mRNA | CTD | PMID:17292431 | Morf4l2 | Rat | valproic acid | decreases expression | ISO | MORF4L2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of MORF4L2 mRNA | CTD | PMID:23179753 and PMID:27188386 | Morf4l2 | Rat | valproic acid | decreases methylation | ISO | MORF4L2 (Homo sapiens) | 6480464 | Valproic Acid results in decreased methylation of MORF4L2 gene | CTD | PMID:29154799 | Morf4l2 | Rat | vancomycin | decreases expression | ISO | Morf4l2 (Mus musculus) | 6480464 | Vancomycin results in decreased expression of MORF4L2 mRNA | CTD | PMID:18930951 | |