Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Gemin8 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Gemin8 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of GEMIN8 mRNA | CTD | PMID:22206623 | Gemin8 | Rat | 17beta-hydroxy-5alpha-androstan-3-one | increases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Dihydrotestosterone results in increased expression of GEMIN8 mRNA | CTD | PMID:29581250 | Gemin8 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | EXP | | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of GEMIN8 mRNA | CTD | PMID:32109520 | Gemin8 | Rat | 2,6-dinitrotoluene | affects expression | EXP | | 6480464 | 2 and 6-dinitrotoluene affects the expression of GEMIN8 mRNA | CTD | PMID:21346803 | Gemin8 | Rat | 3,4-methylenedioxymethamphetamine | decreases expression | ISO | Gemin8 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in decreased expression of GEMIN8 mRNA | CTD | PMID:20188158 | Gemin8 | Rat | 3-isobutyl-1-methyl-7H-xanthine | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GEMIN8 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GEMIN8 mRNA | CTD | PMID:28628672 | Gemin8 | Rat | 4,4'-sulfonyldiphenol | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GEMIN8 mRNA | CTD | PMID:28628672 | Gemin8 | Rat | 5-aza-2'-deoxycytidine | affects expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Decitabine affects the expression of GEMIN8 mRNA | CTD | PMID:23300844 | Gemin8 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of GEMIN8 mRNA | CTD | PMID:30047161 | Gemin8 | Rat | aflatoxin B1 | decreases methylation | ISO | GEMIN8 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of GEMIN8 gene | CTD | PMID:27153756 | Gemin8 | Rat | antirheumatic drug | increases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of GEMIN8 mRNA | CTD | PMID:24449571 | Gemin8 | Rat | aristolochic acid A | decreases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of GEMIN8 mRNA | CTD | PMID:33212167 | Gemin8 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of GEMIN8 mRNA | CTD | PMID:25181051 | Gemin8 | Rat | bisphenol A | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of GEMIN8 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GEMIN8 mRNA | CTD | PMID:28628672 and PMID:31601247 | Gemin8 | Rat | caffeine | decreases phosphorylation | ISO | GEMIN8 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of GEMIN8 protein | CTD | PMID:35688186 | Gemin8 | Rat | cisplatin | affects expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Cisplatin affects the expression of GEMIN8 mRNA | CTD | PMID:23300844 | Gemin8 | Rat | cisplatin | increases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of GEMIN8 mRNA | CTD | PMID:27392435 | Gemin8 | Rat | dexamethasone | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GEMIN8 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GEMIN8 mRNA | CTD | PMID:28628672 | Gemin8 | Rat | dorsomorphin | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Gemin8 | Rat | doxorubicin | decreases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of GEMIN8 mRNA | CTD | PMID:29803840 | Gemin8 | Rat | FR900359 | affects phosphorylation | ISO | GEMIN8 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of GEMIN8 protein | CTD | PMID:37730182 | Gemin8 | Rat | fulvestrant | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [bisphenol A co-treated with Fulvestrant] results in increased methylation of GEMIN8 gene | CTD | PMID:31601247 | Gemin8 | Rat | gentamycin | decreases expression | EXP | | 6480464 | Gentamicins results in decreased expression of GEMIN8 mRNA | CTD | PMID:33387578 | Gemin8 | Rat | indometacin | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of GEMIN8 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of GEMIN8 mRNA | CTD | PMID:28628672 | Gemin8 | Rat | methimazole | decreases expression | EXP | | 6480464 | Methimazole results in decreased expression of GEMIN8 mRNA | CTD | PMID:30047161 | Gemin8 | Rat | methyl methanesulfonate | decreases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in decreased expression of GEMIN8 mRNA | CTD | PMID:23649840 | Gemin8 | Rat | methylmercury chloride | decreases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | methylmercuric chloride results in decreased expression of GEMIN8 mRNA | CTD | PMID:28001369 | Gemin8 | Rat | p-chloromercuribenzoic acid | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GEMIN8 mRNA | CTD | PMID:27188386 | Gemin8 | Rat | phenobarbital | decreases expression | EXP | | 6480464 | Phenobarbital results in decreased expression of GEMIN8 mRNA | CTD | PMID:30047161 | Gemin8 | Rat | phenylmercury acetate | decreases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Phenylmercuric Acetate results in decreased expression of GEMIN8 mRNA | CTD | PMID:26272509 | Gemin8 | Rat | phenylmercury acetate | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in decreased expression of GEMIN8 mRNA | CTD | PMID:27188386 | Gemin8 | Rat | potassium dichromate | increases expression | ISO | Gemin8 (Mus musculus) | 6480464 | Potassium Dichromate results in increased expression of GEMIN8 mRNA | CTD | PMID:23608068 | Gemin8 | Rat | SB 431542 | multiple interactions | ISO | GEMIN8 (Homo sapiens) | 6480464 | [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... | CTD | PMID:27188386 | Gemin8 | Rat | Soman | decreases expression | EXP | | 6480464 | Soman results in decreased expression of GEMIN8 mRNA | CTD | PMID:19281266 | Gemin8 | Rat | sulfadimethoxine | decreases expression | EXP | | 6480464 | Sulfadimethoxine results in decreased expression of GEMIN8 mRNA | CTD | PMID:30047161 | Gemin8 | Rat | triptonide | affects expression | ISO | Gemin8 (Mus musculus) | 6480464 | triptonide affects the expression of GEMIN8 mRNA | CTD | PMID:33045310 | Gemin8 | Rat | valproic acid | decreases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Valproic Acid results in decreased expression of GEMIN8 mRNA | CTD | PMID:23179753 | Gemin8 | Rat | valproic acid | increases expression | ISO | GEMIN8 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of GEMIN8 mRNA | CTD | PMID:28001369 | Gemin8 | Rat | vinclozolin | decreases expression | EXP | | 6480464 | vinclozolin results in decreased expression of GEMIN8 mRNA | CTD | PMID:23034163 | |