Or13c7 (olfactory receptor family 13 subfamily C member 7) - Rat Genome Database

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Gene: Or13c7 (olfactory receptor family 13 subfamily C member 7) Rattus norvegicus
Analyze
Symbol: Or13c7
Name: olfactory receptor family 13 subfamily C member 7
RGD ID: 1333374
Description: Predicted to enable olfactory receptor activity. Predicted to be involved in detection of chemical stimulus involved in sensory perception of smell. Predicted to be active in plasma membrane. Orthologous to human OR13C7 (olfactory receptor family 13 subfamily C member 7 (gene/pseudogene)); INTERACTS WITH bisphenol A; copper(II) sulfate (ortholog); crocidolite asbestos (ortholog).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: olfactory receptor 840; olfactory receptor gene Olr840; olfactory receptor Olr840; Olr840
RGD Orthologs
Human
Mouse
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8562,876,908 - 62,877,867 (+)NCBIGRCr8
mRatBN7.2558,081,150 - 58,082,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl558,077,726 - 58,083,852 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx560,061,728 - 60,062,687 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0561,880,539 - 61,881,498 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0561,851,247 - 61,852,206 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0559,326,803 - 59,327,762 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl559,326,803 - 59,327,762 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0563,850,377 - 63,851,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4560,315,547 - 60,316,506 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1560,315,725 - 60,316,685 (+)NCBI
Celera556,659,602 - 56,660,561 (+)NCBICelera
Cytogenetic Map5q22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Genome sequence of the Brown Norway rat yields insights into mammalian evolution. Gibbs RA, etal., Nature 2004 Apr 1;428(6982):493-521.
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions

Genomics

Comparative Map Data
Or13c7
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8562,876,908 - 62,877,867 (+)NCBIGRCr8
mRatBN7.2558,081,150 - 58,082,109 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl558,077,726 - 58,083,852 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx560,061,728 - 60,062,687 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0561,880,539 - 61,881,498 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0561,851,247 - 61,852,206 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.0559,326,803 - 59,327,762 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl559,326,803 - 59,327,762 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0563,850,377 - 63,851,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4560,315,547 - 60,316,506 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1560,315,725 - 60,316,685 (+)NCBI
Celera556,659,602 - 56,660,561 (+)NCBICelera
Cytogenetic Map5q22NCBI
OR2S2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38935,957,108 - 35,958,154 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl935,957,108 - 35,958,154 (-)EnsemblGRCh38hg38GRCh38
GRCh37935,957,105 - 35,958,151 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36935,947,136 - 35,948,065 (-)NCBINCBI36Build 36hg18NCBI36
Build 34935,947,135 - 35,948,065NCBI
Celera935,890,670 - 35,891,716 (-)NCBICelera
Cytogenetic Map9p13.3NCBI
HuRef935,910,882 - 35,911,928 (-)NCBIHuRef
CHM1_1935,957,360 - 35,958,406 (-)NCBICHM1_1
T2T-CHM13v2.0935,978,781 - 35,979,827 (-)NCBIT2T-CHM13v2.0
Or13c7
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39443,854,292 - 43,855,463 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl443,851,565 - 43,857,595 (+)EnsemblGRCm39 Ensembl
GRCm38443,854,292 - 43,855,463 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl443,851,565 - 43,857,595 (+)EnsemblGRCm38mm10GRCm38
MGSCv37443,867,164 - 43,868,335 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36443,875,392 - 43,876,563 (+)NCBIMGSCv36mm8
Celera443,879,160 - 43,880,331 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map423.05NCBI

Variants

.
Variants in Or13c7
1 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:83
Count of miRNA genes:71
Interacting mature miRNAs:72
Transcripts:ENSRNOT00000052426
Prediction methods:Microtar, Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1578776Stresp18Stress response QTL 182.9thymus mass (VT:0004954)thymus wet weight (CMO:0000855)52795544072955440Rat
1298067Scl15Serum cholesterol level QTL 154.80.001blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)53321566578215665Rat
1300115Hrtrt7Heart rate QTL 72.76heart pumping trait (VT:2000009)heart rate (CMO:0000002)54786906290099692Rat
1549845Scl44Serum cholesterol level QTL 446blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)540128307148607290Rat
70212Niddm25Non-insulin dependent diabetes mellitus QTL 253.54blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)51131345958Rat
1358353Srcrtb2Stress Responsive Cort Basal QTL 23.480.003blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)51887394774251464Rat
634305Mamtr1Mammary tumor resistance QTL 10.0001mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)512789751113558310Rat
1331801Rf33Renal function QTL 334.149kidney blood vessel physiology trait (VT:0100012)absolute change in renal vascular resistance (CMO:0001900)543726656129132602Rat
1598807Glom12Glomerulus QTL 122.7kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)53321566578215665Rat
1302786Kidm8Kidney mass QTL 828.15kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)53321566578215665Rat
6903292Stl28Serum triglyceride level QTL 282.60.0073blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)52851548973515489Rat
1578766Tcas11Tongue tumor susceptibility QTL 114.12tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)546711509161317411Rat
1578767Stresp17Stress response QTL 174.30.01blood aldosterone amount (VT:0005346)plasma aldosterone level (CMO:0000551)52795544072955440Rat
7411561Bw134Body weight QTL 134240.001body mass (VT:0001259)body weight gain (CMO:0000420)54946360094463600Rat
1641922Alcrsp8Alcohol response QTL 8alcohol metabolism trait (VT:0015089)blood ethanol level (CMO:0000535)53518915368564008Rat
2303615Vencon7Ventilatory control QTL 70.001respiration trait (VT:0001943)respiration rate (CMO:0000289)55098389595983895Rat
1576312Emca8Estrogen-induced mammary cancer QTL 84.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)550328551141643988Rat
1641912Alcrsp18Alcohol response QTL 18response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)535189153141643988Rat
1576314Eutr1Estrogen induced uterine response QTL 1uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)52138965166875058Rat
6903306Scl35Serum cholesterol QTL 352.60.0073blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)52851548973515489Rat
1576317Eutr2Estrogen induced uterine response QTL 20.01uterus integrity trait (VT:0010575)pyometritis severity score (CMO:0002009)534730116104251008Rat
7394712Emca13Estrogen-induced mammary cancer QTL 13mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)5982326699753708Rat
1331773Scl26Serum cholesterol level QTL 263.065blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)54372665686724018Rat
70189Mcs5Mammary carcinoma susceptibility QTL 510.51mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)555805606132207589Rat
1331771Rf35Renal function QTL 354.36965kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)572947086724018Rat
61359EaexExperimental allergic encephalomyelitis QTL x3nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)555715622100715622Rat
8662454Vetf3Vascular elastic tissue fragility QTL 327.4artery integrity trait (VT:0010639)number of ruptures of the internal elastic lamina of the abdominal aorta and iliac arteries (CMO:0002562)5228222669540447Rat
2290448Scl54Serum cholesterol level QTL 542.93blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)531663789131345958Rat
9589025Epfw7Epididymal fat weight QTL 720.660.001epididymal fat pad mass (VT:0010421)epididymal fat pad weight to body weight ratio (CMO:0000658)54946360094463600Rat
2303574Gluco42Glucose level QTL 422blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)55349671998496719Rat
1331756Rf34Renal function QTL 344.16275kidney blood vessel physiology trait (VT:0100012)absolute change in renal blood flow rate (CMO:0001168)5190450412Rat
8552954Pigfal14Plasma insulin-like growth factor 1 level QTL 149blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)52122674466226744Rat
2316959Gluco59Glucose level QTL 594.7blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)534944474113558310Rat
1600358Mamtr5Mammary tumor resistance QTL 5mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)51887394763873947Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
ectoderm
endocrine system
endoderm
hemolymphoid system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
1 5 2 4 1 1 4 2 3 1 10 4

Sequence


Ensembl Acc Id: ENSRNOT00000050490   ⟹   ENSRNOP00000040530
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,077,726 - 58,083,852 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000052426   ⟹   ENSRNOP00000041214
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl559,326,803 - 59,327,762 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000105443   ⟹   ENSRNOP00000078287
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl558,077,906 - 58,083,852 (+)Ensembl
RefSeq Acc Id: NM_001000414   ⟹   NP_001000414
RefSeq Status: REVIEWED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8562,876,908 - 62,877,867 (+)NCBI
mRatBN7.2558,081,150 - 58,082,109 (+)NCBI
Rnor_6.0559,326,803 - 59,327,762 (+)NCBI
Rnor_5.0563,850,377 - 63,851,336 (+)NCBI
RGSC_v3.4560,315,547 - 60,316,506 (+)RGD
Celera556,659,602 - 56,660,561 (+)RGD
Sequence:
Protein Sequences
Protein RefSeqs NP_001000414 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein EDL98777 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000040530.5
  ENSRNOP00000078287.1
RefSeq Acc Id: NP_001000414   ⟸   NM_001000414
- UniProtKB: D4AA28 (UniProtKB/TrEMBL),   A6IJ57 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000041214   ⟸   ENSRNOT00000052426
Ensembl Acc Id: ENSRNOP00000040530   ⟸   ENSRNOT00000050490
Ensembl Acc Id: ENSRNOP00000078287   ⟸   ENSRNOT00000105443
Protein Domains
G-protein coupled receptors family 1 profile

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-D3ZLK0-F1-model_v2 AlphaFold D3ZLK0 1-319 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1333374 AgrOrtholog
BioCyc Gene G2FUF-41483 BioCyc
Ensembl Genes ENSRNOG00000030761 Ensembl
  ENSRNOG00000068857 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000050490.5 UniProtKB/TrEMBL
  ENSRNOT00000105443.1 UniProtKB/TrEMBL
Gene3D-CATH Rhodopsin 7-helix transmembrane proteins UniProtKB/TrEMBL
InterPro 7TM_GPCR_Rhodpsn UniProtKB/TrEMBL
  GPCR_Rhodpsn_supfam UniProtKB/TrEMBL
  Olfact_rcpt UniProtKB/TrEMBL
KEGG Report rno:298733 UniProtKB/TrEMBL
NCBI Gene 298733 ENTREZGENE
PANTHER OLFACTORY RECEPTOR UniProtKB/TrEMBL
  OLFACTORY RECEPTOR UniProtKB/TrEMBL
Pfam 7tm_4 UniProtKB/TrEMBL
PhenoGen Or13c7 PhenoGen
PRINTS GPCRRHODOPSN UniProtKB/TrEMBL
  OLFACTORYR UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_1 UniProtKB/TrEMBL
  G_PROTEIN_RECEP_F1_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000030761 RatGTEx
  ENSRNOG00000068857 RatGTEx
Superfamily-SCOP Family A G protein-coupled receptor-like UniProtKB/TrEMBL
UniProt A6IJ57 ENTREZGENE, UniProtKB/TrEMBL
  D4AA28 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2022-08-16 Or13c7  olfactory receptor family 13 subfamily C member 7  Olr840  olfactory receptor 840  Symbol and Name Changed 1299863 APPROVED
2008-04-30 Olr840  olfactory receptor 840   Olr840_predicted  olfactory receptor 840 (predicted)  'predicted' is removed 2292626 APPROVED
2005-02-04 Olr840_predicted  olfactory receptor 840 (predicted)      Symbol and Name status set to approved 70820 APPROVED