Tnnc2 (troponin C2, fast skeletal type) - Rat Genome Database

Send us a Message
Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   
Search RGD Grant Resources Citing RGD About Us Contact Us
Genes Variants Community Projects QTLs Strains Markers Genome Information Ontologies Cell Lines References Download Submit Data
OntoMate (Literature Search) JBrowse (Genome Browser) Synteny Browser (VCMap) Variant Visualizer Multi-Ontology Enrichment (MOET) Gene-Ortholog Location Finder (GOLF) InterViewer (Protein-Protein Interactions) PhenoMiner (Quatitative Phenotypes) Gene Annotator OLGA (Gene List Generator) AllianceMine GViewer (Genome Viewer)
Aging & Age-Related Disease Cancer & Neoplastic Disease Cardiovascular Disease Coronavirus Disease Developmental Disease Diabetes Hematologic Disease Immune & Inflammatory Disease Infectious Disease Liver Disease Neurological Disease Obesity & Metabolic Syndrome Renal Disease Respiratory Disease Sensory Organ Disease
Find Models   new Genetic Models Autism Models Rat PhenoMiner (Quantitative Phenotypes) Chinchilla PhenoMiner Expected Ranges (Quantitative Phenotype) PhenoMiner Term Comparison Hybrid Rat Diversity Panel Phenotypes Phenotypes in Other Animal Models Animal Husbandry Strain Medical Records Phylogenetics Strain Availability Calendar Rats 101 Submissions Photo Archive
Pathways
Rat Community Forum Directory of Rat Laboratories Video Tutorials News RGD Publications RGD Presentations Archive Nomenclature Guidelines Resource Links Laboratory Resources Employment Resources
Gene: Tnnc2 (troponin C2, fast skeletal type) Rattus norvegicus
Analyze
Symbol: Tnnc2
Name: troponin C2, fast skeletal type
RGD ID: 1311973
Description: Predicted to enable calcium ion binding activity. Predicted to contribute to actin binding activity. Predicted to be involved in regulation of muscle contraction and skeletal muscle contraction. Predicted to be part of troponin complex. Human ortholog(s) of this gene implicated in congenital myopathy 15. Orthologous to human TNNC2 (troponin C2, fast skeletal type); PARTICIPATES IN acebutolol pharmacodynamics pathway; adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway; amiodarone pharmacodynamics pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: LOC296369; skeletal troponin C; troponin C type 2 (fast); troponin C, skeletal muscle; troponin C2, fast
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,932,611 - 173,935,339 (-)NCBIGRCr8
mRatBN7.23153,513,272 - 153,516,033 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,513,271 - 153,516,029 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,321,952 - 157,324,670 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,820,922 - 165,823,640 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,564,699 - 163,567,417 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,243,607 - 161,246,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,243,587 - 161,246,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,429,345 - 167,430,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,807,133 - 155,808,219 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,713,032 - 155,715,733 (-)NCBI
Celera3152,121,028 - 152,123,756 (-)NCBICelera
Cytogenetic Map3q42NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component
troponin complex  (IBA,ISO)

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
acebutolol pharmacodynamics pathway   (ISO)
adrenergic beta receptor agonist and beta-blocker pharmacodynamics pathway  (ISO)
amiodarone pharmacodynamics pathway  (ISO)
amlodipine pharmacodynamics pathway  (ISO)
atenolol pharmacodynamics pathway  (ISO)
betaxolol pharmacodynamics pathway  (ISO)
bisoprolol pharmacodynamics pathway  (ISO)
bupranolol drug pathway  (ISO)
bupranolol pharmacodynamics pathway   (ISO)
calcium/calcium-mediated signaling pathway  (IEA,ISO)
carvedilol pharmacodynamics pathway  (ISO)
diltiazem pharmacodynamics pathway  (ISO)
disopyramide pharmacodynamics pathway  (ISO)
dobutamine pharmacodynamics pathway  (ISO)
esmolol pharmacodynamics pathway  (ISO)
flecainde pharmacodynamics pathway  (ISO)
fosphenytoin pharmacodynamics pathway  (ISO)
ibutilide pharmacodynamics pathway  (ISO)
isoprenaline pharmacodynamics pathway  (ISO)
isradipine pharmacodynamics pathway  (ISO)
levobunolol pharmacodynamics pathway  (ISO)
lidocaine pharmacodynamics pathway  (ISO)
metoprolol pharmacodynamics pathway  (ISO)
mexiletine pharmacodynamics pathway  (ISO)
nadolol pharmacodynamics pathway  (ISO)
nebivolol pharmacodynamics pathway  (ISO)
nifedipine pharmacodynamics pathway  (ISO)
nimodipine pharmacodynamics pathway  (ISO)
nisoldipine pharmacodynamics pathway  (ISO)
nitrendipine pharmacodynamics pathway  (ISO)
penbutolol pharmacodynamics pathway  (ISO)
phenytoin pharmacodynamics pathway  (ISO)
pindolol pharmacodynamics pathway  (ISO)
procainamide pharmacodynamics pathway  (ISO)
propranolol pharmacodynamics pathway  (ISO)
quinidine pharmacodynamics pathway  (ISO)
sotalol pharmacodynamics pathway  (ISO)
timolol pharmacodynamics pathway  (ISO)
verapamil pharmacodynamics pathway  (ISO)

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from GOA human gene data--August 2006 GOA data from the GO Consortium
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. SMPDB Annotation Import Pipeline Pipeline to import SMPDB annotations from SMPDB into RGD
5. GOA pipeline RGD automated data pipeline
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Calcium, troponin, calmodulin, S100 proteins: from myocardial basics to new therapeutic strategies. Schaub MC and Heizmann CW, Biochem Biophys Res Commun. 2008 Apr 25;369(1):247-64. Epub 2007 Oct 25.
Additional References at PubMed
PMID:6179945   PMID:16839517   PMID:17194691   PMID:19182904  


Genomics

Comparative Map Data
Tnnc2
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83173,932,611 - 173,935,339 (-)NCBIGRCr8
mRatBN7.23153,513,272 - 153,516,033 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3153,513,271 - 153,516,029 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3157,321,952 - 157,324,670 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03165,820,922 - 165,823,640 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03163,564,699 - 163,567,417 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03161,243,607 - 161,246,335 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3161,243,587 - 161,246,351 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03167,429,345 - 167,430,429 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43155,807,133 - 155,808,219 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.13155,713,032 - 155,715,733 (-)NCBI
Celera3152,121,028 - 152,123,756 (-)NCBICelera
Cytogenetic Map3q42NCBI
TNNC2
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh382045,823,214 - 45,833,306 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl2045,823,214 - 45,833,745 (-)EnsemblGRCh38hg38GRCh38
GRCh372044,451,853 - 44,455,951 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362043,885,260 - 43,889,360 (-)NCBINCBI36Build 36hg18NCBI36
Build 342043,885,263 - 43,889,360NCBI
Celera2041,162,347 - 41,166,448 (-)NCBICelera
Cytogenetic Map20q13.12NCBI
HuRef2041,193,614 - 41,197,713 (-)NCBIHuRef
CHM1_12044,354,991 - 44,359,091 (-)NCBICHM1_1
T2T-CHM13v2.02047,559,705 - 47,569,768 (-)NCBIT2T-CHM13v2.0
Tnnc2
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392164,619,081 - 164,621,654 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2164,619,081 - 164,621,887 (-)EnsemblGRCm39 Ensembl
GRCm382164,777,161 - 164,779,734 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2164,777,161 - 164,779,967 (-)EnsemblGRCm38mm10GRCm38
MGSCv372164,602,661 - 164,605,234 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362164,468,366 - 164,470,939 (-)NCBIMGSCv36mm8
Celera2170,714,468 - 170,717,041 (-)NCBICelera
Cytogenetic Map2H3NCBI
cM Map285.27NCBI
Tnnc2
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495544511,466,579 - 11,469,123 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495544511,466,579 - 11,469,123 (+)NCBIChiLan1.0ChiLan1.0
TNNC2
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22151,565,060 - 51,575,559 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12051,558,160 - 51,568,463 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02042,162,502 - 42,172,829 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12043,249,725 - 43,260,984 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2043,249,725 - 43,254,134 (-)Ensemblpanpan1.1panPan2
TNNC2
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12433,136,644 - 33,139,289 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2433,128,290 - 33,163,050 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2432,663,877 - 32,666,541 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02433,847,135 - 33,849,798 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2433,847,144 - 33,849,791 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12433,105,691 - 33,108,351 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02433,220,760 - 33,223,430 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02433,759,900 - 33,762,559 (-)NCBIUU_Cfam_GSD_1.0
Tnnc2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640191,742,934 - 191,745,960 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365147,196,536 - 7,199,649 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365147,196,576 - 7,199,603 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TNNC2
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1748,024,687 - 48,028,651 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11748,025,621 - 48,026,762 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21753,671,689 - 53,672,831 (-)NCBISscrofa10.2Sscrofa10.2susScr3
TNNC2
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1218,051,708 - 18,063,108 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl218,061,492 - 18,062,971 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366605066,691,630 - 66,703,067 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0

Variants

.
Variants in Tnnc2
3 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:81
Count of miRNA genes:72
Interacting mature miRNAs:74
Transcripts:ENSRNOT00000020348
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2312659Slep7Serum leptin concentration QTL 70.001blood leptin amount (VT:0005667)serum leptin level (CMO:0000780)398535255168026850Rat
2312670Bw94Body weight QTL 940.01inguinal fat pad mass (VT:0010424)inguinal fat pad weight to body weight ratio (CMO:0001253)398535255168026850Rat
2312673Scl63Serum cholesterol level QTL 630.001blood cholesterol amount (VT:0000180)serum total cholesterol level (CMO:0000363)398535255168026850Rat
1298068Bp167Blood pressure QTL 1670.004arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141074471169034231Rat
631673Iddm13Insulin dependent diabetes mellitus QTL 131.30.663blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)3130193298161695983Rat
9589106Insul23Insulin level QTL 2313.860.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)3131635904169034231Rat
8552791Vie2Viral induced encephalitis QTL 24.1brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)3145956084169034231Rat
631541Bp81Blood pressure QTL 814arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3124122556169034231Rat
631841Niddm39Non-insulin dependent diabetes mellitus QTL 393.36blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)394856903159898684Rat
8552952Pigfal13Plasma insulin-like growth factor 1 level QTL 13blood insulin-like growth factor amount (VT:0010479)plasma insulin-like growth factor 1 level (CMO:0001299)3138799500169034231Rat
8662816Vetf4Vascular elastic tissue fragility QTL 44renal artery integrity trait (VT:0010642)number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)359242096157323038Rat
1300113Bp176Blood pressure QTL 1763.9arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145956084157309487Rat
1300159Kidm4Kidney mass QTL 43.83kidney mass (VT:0002707)right kidney wet weight to body weight ratio (CMO:0001953)3121056165157309487Rat
1331726Bp208Blood pressure QTL 2083.129arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3141339013162184794Rat
1578656Vnigr2Vascular neointimal growth QTL 24.2artery morphology trait (VT:0002191)lesioned artery residual lumen area (CMO:0001417)3130656562169034231Rat
1559282Emca5Estrogen-induced mammary cancer QTL 53.9mammary gland integrity trait (VT:0010552)percentage of study population developing mammary tumors during a period of time (CMO:0000948)343827364169034231Rat
1578653Vnigr3Vascular neointimal growth QTL 33.1artery morphology trait (VT:0002191)artery neointimal hyperplastic lesion area (CMO:0001414)3130656562169034231Rat
1581568Rf53Renal function QTL 53urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)356395968161299569Rat
1598854Memor10Memory QTL 102exploratory behavior trait (VT:0010471)average horizontal distance between subject and target during voluntary locomotion in an experimental apparatus (CMO:0002674)3145956084161299569Rat
1598877Bp285Blood pressure QTL 2851.50.03arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3120538241165538241Rat
1576306Schws3Schwannoma susceptibility QTL 30.001nervous system integrity trait (VT:0010566)percentage of study population developing trigeminal nerve neurilemmomas during a period of time (CMO:0002017)3118839124163839124Rat
1578754Stresp16Stress response QTL 1640.001blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)3112681431157681431Rat
1578666Vnigr1Vascular neointimal growth QTL 14.6artery morphology trait (VT:0002191)artery lumen area (CMO:0001409)3149040888168026850Rat
61335Bp20Blood pressure QTL 203arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)3141339236155617360Rat
70216Cm14Cardiac mass QTL 142.1heart mass (VT:0007028)heart wet weight (CMO:0000069)331172320163586636Rat
2298477Eau4Experimental allergic uveoretinitis QTL 40.0011uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)3137398739169034231Rat
2301411Bp320Blood pressure QTL 3200.001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)3145925360166177555Rat
2301971Cm71Cardiac mass QTL 714.63heart left ventricle mass (VT:0007031)heart left ventricle weight (CMO:0000776)341874578155617519Rat
2303620Vencon4Ventilatory control QTL 43.9respiration trait (VT:0001943)tidal volume (CMO:0000222)3127162703168026850Rat
2317883Alcrsp26Alcohol response QTL 261.80.63response to alcohol trait (VT:0010489)duration of loss of righting reflex (CMO:0002289)3145526770169034231Rat
12879873Cm96Cardiac mass QTL 960.001heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)3145925360166177555Rat
2301970Bw81Body weight QTL 815.19body mass (VT:0001259)body weight (CMO:0000012)341874578155617519Rat
2302373Gluco39Glucose level QTL 395.01blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)398535386161695835Rat
12879875Kidm64Kidney mass QTL 640.001kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3145925360166177555Rat
12879876Bw182Body weight QTL 1820.003body mass (VT:0001259)body weight (CMO:0000012)3145925360166177555Rat
12879872Cm97Cardiac mass QTL 970.001heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)3145925360166177555Rat
12879871Am7Aortic mass QTL 70.001aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)3145925360166177555Rat
12879874Cm98Cardiac mass QTL 980.005heart right ventricle mass (VT:0007033)heart right ventricle weight to body weight ratio (CMO:0000914)3145925360166177555Rat
10755461Coatc16Coat color QTL 16coat/hair pigmentation trait (VT:0010463)pigmented ventral coat/hair area to total ventral coat/hair area ratio (CMO:0001812)3122438700167438700Rat

Markers in Region
Tncs  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.23153,513,814 - 153,514,468 (+)MAPPERmRatBN7.2
Rnor_6.03161,244,150 - 161,244,803NCBIRnor6.0
Rnor_5.03167,429,748 - 167,430,401UniSTSRnor5.0
RGSC_v3.43155,807,536 - 155,808,189UniSTSRGSC3.4
Celera3152,121,571 - 152,122,224UniSTS
Cytogenetic Map3q42UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High 8 11 8
Medium 1 9 6 3 6 13 13 7
Low 3 24 34 21 16 21 34 32 25 4
Below cutoff 18 14 14 14 25 3 3

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001037351 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC105815 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474005 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ273679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ215069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216531 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216940 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ216956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217047 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217195 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217236 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217371 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217706 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217788 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217840 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217842 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217896 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217902 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217974 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ217984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218048 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ218061 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223572 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223623 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223636 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223643 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223690 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223692 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223711 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223713 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223773 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223816 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223832 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ223986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224079 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224128 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224223 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224258 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224376 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224387 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224450 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224462 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224648 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224672 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224735 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224811 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224822 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ224827 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  J00793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSRNOT00000020348   ⟹   ENSRNOP00000020348
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,513,276 - 153,516,029 (-)Ensembl
Rnor_6.0 Ensembl3161,243,587 - 161,246,351 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000098001   ⟹   ENSRNOP00000084039
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl3153,513,271 - 153,514,652 (-)Ensembl
RefSeq Acc Id: NM_001037351   ⟹   NP_001032428
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr83173,932,611 - 173,935,339 (-)NCBI
mRatBN7.23153,513,272 - 153,516,000 (-)NCBI
Rnor_6.03161,243,607 - 161,246,335 (-)NCBI
Rnor_5.03167,429,345 - 167,430,429 (-)NCBI
RGSC_v3.43155,807,133 - 155,808,219 (-)RGD
Celera3152,121,028 - 152,123,756 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001032428 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein ABB51540 (Get FASTA)   NCBI Sequence Viewer  
  EDL96496 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSRNOP00000020348
  ENSRNOP00000020348.5
  ENSRNOP00000084039.1
Reference Protein Sequences
RefSeq Acc Id: NP_001032428   ⟸   NM_001037351
- UniProtKB: Q304F3 (UniProtKB/TrEMBL),   F2Z3S8 (UniProtKB/TrEMBL),   A6JXB3 (UniProtKB/TrEMBL),   A0A8I5ZWE4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000020348   ⟸   ENSRNOT00000020348
RefSeq Acc Id: ENSRNOP00000084039   ⟸   ENSRNOT00000098001
Protein Domains
EF-hand

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q304F3-F1-model_v2 AlphaFold Q304F3 1-160 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13692665
Promoter ID:EPDNEW_R3189
Type:multiple initiation site
Name:Tnnc2_1
Description:troponin C2, fast skeletal type
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.03161,246,306 - 161,246,366EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311973 AgrOrtholog
BioCyc Gene G2FUF-46829 BioCyc
Ensembl Genes ENSRNOG00000015155 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000020348 ENTREZGENE
  ENSRNOT00000020348.7 UniProtKB/TrEMBL
  ENSRNOT00000098001.1 UniProtKB/TrEMBL
Gene3D-CATH EF-hand UniProtKB/TrEMBL
InterPro EF-hand-like_dom UniProtKB/TrEMBL
  EF_Hand_1_Ca_BS UniProtKB/TrEMBL
  EF_hand_Ca-bd UniProtKB/TrEMBL
KEGG Report rno:296369 UniProtKB/TrEMBL
NCBI Gene 296369 ENTREZGENE
PANTHER MYOSIN LIGHT CHAIN 1, 3 UniProtKB/TrEMBL
  TROPONIN C2, FAST SKELETAL TYPE UniProtKB/TrEMBL
Pfam EF_hand_5 UniProtKB/TrEMBL
PhenoGen Tnnc2 PhenoGen
PROSITE EF_HAND_1 UniProtKB/TrEMBL
  EF_HAND_2 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000015155 RatGTEx
SMART EFh UniProtKB/TrEMBL
Superfamily-SCOP SSF47473 UniProtKB/TrEMBL
UniProt A0A8I5ZWE4 ENTREZGENE, UniProtKB/TrEMBL
  A6JXB3 ENTREZGENE
  F2Z3S8 ENTREZGENE
  Q304F3 ENTREZGENE, UniProtKB/TrEMBL
UniProt Secondary A6JXB3 UniProtKB/TrEMBL
  F2Z3S8 UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-02-24 Tnnc2  troponin C2, fast skeletal type  Tnnc2  troponin C type 2 (fast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-10-23 Tnnc2  troponin C type 2 (fast)  Tnnc2  troponin C2, fast  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Tnnc2  troponin C2, fast  Tnnc2  troponin C type 2 (fast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-30 Tnnc2  troponin C type 2 (fast)    troponin C2, fast  Name updated 1299863 APPROVED
2005-12-06 Tnnc2  troponin C2, fast  Tnnc2_predicted  troponin C2, fast (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tnnc2_predicted  troponin C2, fast (predicted)      Symbol and Name status set to approved 70820 APPROVED