Lin54 (lin-54 DREAM MuvB core complex component) - Rat Genome Database

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Gene: Lin54 (lin-54 DREAM MuvB core complex component) Rattus norvegicus
Analyze
Symbol: Lin54
Name: lin-54 DREAM MuvB core complex component
RGD ID: 1311361
Description: Predicted to enable minor groove of adenine-thymine-rich DNA binding activity and transcription regulatory region nucleic acid binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to act upstream of or within nucleosome organization. Predicted to be part of RNA polymerase II transcription repressor complex. Predicted to be active in nucleus. Orthologous to human LIN54 (lin-54 DREAM MuvB core complex component); INTERACTS WITH bisphenol A; cadmium dichloride; cobalt dichloride.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: lin-54 homolog (C. elegans); LOC305171; protein lin-54 homolog; RGD1311361; similar to hypothetical protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,434,093 - 9,514,091 (+)NCBIGRCr8
mRatBN7.2149,129,775 - 9,188,244 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl149,130,336 - 9,187,790 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx149,117,967 - 9,159,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01410,417,843 - 10,459,523 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0149,114,446 - 9,156,126 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01410,770,072 - 10,828,115 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1410,786,399 - 10,828,106 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01410,717,462 - 10,775,710 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41410,398,080 - 10,439,960 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11410,383,795 - 10,439,950 (+)NCBI
Celera149,254,128 - 9,295,581 (+)NCBICelera
Cytogenetic Map14p22NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
3. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932  


Genomics

Comparative Map Data
Lin54
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8149,434,093 - 9,514,091 (+)NCBIGRCr8
mRatBN7.2149,129,775 - 9,188,244 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl149,130,336 - 9,187,790 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx149,117,967 - 9,159,651 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01410,417,843 - 10,459,523 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0149,114,446 - 9,156,126 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01410,770,072 - 10,828,115 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1410,786,399 - 10,828,106 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01410,717,462 - 10,775,710 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41410,398,080 - 10,439,960 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11410,383,795 - 10,439,950 (+)NCBI
Celera149,254,128 - 9,295,581 (+)NCBICelera
Cytogenetic Map14p22NCBI
LIN54
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38482,924,603 - 83,012,941 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl482,909,973 - 83,012,926 (-)EnsemblGRCh38hg38GRCh38
GRCh37483,845,756 - 83,934,094 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36484,065,151 - 84,151,006 (-)NCBINCBI36Build 36hg18NCBI36
Celera481,136,312 - 81,224,592 (-)NCBICelera
Cytogenetic Map4q21.22NCBI
HuRef479,586,333 - 79,674,722 (-)NCBIHuRef
CHM1_1483,822,194 - 83,910,549 (-)NCBICHM1_1
T2T-CHM13v2.0486,253,801 - 86,342,186 (-)NCBIT2T-CHM13v2.0
Lin54
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm395100,589,892 - 100,648,506 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl5100,589,900 - 100,648,493 (-)EnsemblGRCm39 Ensembl
GRCm385100,442,033 - 100,500,639 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl5100,441,918 - 100,500,639 (-)EnsemblGRCm38mm10GRCm38
MGSCv375100,871,052 - 100,929,658 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv365100,682,502 - 100,740,941 (-)NCBIMGSCv36mm8
Celera597,767,830 - 97,826,649 (-)NCBICelera
Cytogenetic Map5E4NCBI
cM Map548.48NCBI
Lin54
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554746,613,661 - 6,660,899 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554746,600,766 - 6,660,904 (+)NCBIChiLan1.0ChiLan1.0
LIN54
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2347,060,208 - 47,146,279 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1447,249,393 - 47,335,806 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0441,192,653 - 41,278,730 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1447,045,043 - 47,131,091 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl447,046,277 - 47,131,091 (+)Ensemblpanpan1.1panPan2
LIN54
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1326,876,111 - 6,940,754 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl326,878,187 - 6,941,268 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3234,943,820 - 35,009,627 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0326,896,796 - 6,962,825 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl326,896,805 - 6,960,655 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1326,967,885 - 7,033,859 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0326,836,618 - 6,902,413 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03233,063,699 - 33,129,725 (+)NCBIUU_Cfam_GSD_1.0
Lin54
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244052855,405,363 - 5,481,497 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049367381,568,585 - 1,643,454 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049367381,568,786 - 1,643,500 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
LIN54
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl8135,330,919 - 135,398,263 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.18135,330,868 - 135,398,274 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.28144,625,750 - 144,693,415 (+)NCBISscrofa10.2Sscrofa10.2susScr3
LIN54
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1731,323,792 - 31,406,194 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl731,326,174 - 31,404,045 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660379,893,341 - 9,984,470 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Lin54
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462490012,174 - 66,648 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462490012,511 - 66,582 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Lin54
202 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:670
Count of miRNA genes:298
Interacting mature miRNAs:381
Transcripts:ENSRNOT00000003006
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1300114Srn2Serum renin concentration QTL 23.27blood renin amount (VT:0003349)plasma renin activity level (CMO:0000116)14381307421217635Rat
2293089Iddm31Insulin dependent diabetes mellitus QTL 314.7blood glucose amount (VT:0000188)age at onset/diagnosis of type 1 diabetes mellitus (CMO:0001140)14381307418274691Rat
1581500Renag1Renal agenesis QTL 1kidney development trait (VT:0000527)percentage of study population developing unilateral renal agenesis during a period of time (CMO:0000940)14817066868298175Rat
731183Pia20Pristane induced arthritis QTL 203.55joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)14908897839057237Rat
1331740Bw26Body weight QTL 263.028body mass (VT:0001259)body weight (CMO:0000012)14381307430767156Rat
619619Rf4Renal disease susceptibility QTL 44.10.002urine total protein amount (VT:0000032)urine protein excretion rate to body weight ratio (CMO:0001099)14132754612Rat
71115Niddm15Non-insulin dependent diabetes mellitus QTL 154.8blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)14121760611030812Rat
1358296Ael3Aortic elastin QTL 33.70.00051aorta elastin amount (VT:0003905)aortic elastin14826709053267090Rat
70195Mcs8Mammary carcinoma susceptibility QTL 84.28mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)14381307424531477Rat
2300183Bmd60Bone mineral density QTL 605.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
634352Apr6Acute phase response QTL 63.7blood interleukin-6 amount (VT:0008595)plasma interleukin-6 level (CMO:0001927)14141131407Rat
2300159Bmd61Bone mineral density QTL 615.30.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)14126541967Rat
70204Niddm20Non-insulin dependent diabetes mellitus QTL 205.10.000008blood glucose amount (VT:0000188)blood glucose level area under curve (AUC) (CMO:0000350)14121760616960180Rat
2302045Pia39Pristane induced arthritis QTL 394.90.001blood immunoglobulin amount (VT:0002460)serum immunoglobulin G2a level (CMO:0002116)14826709053267090Rat

Markers in Region
D16S2625  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2149,180,365 - 9,180,793 (+)MAPPERmRatBN7.2
Rnor_6.01410,820,681 - 10,821,108NCBIRnor6.0
Rnor_5.01410,768,276 - 10,768,703UniSTSRnor5.0
RGSC_v3.41410,432,526 - 10,432,953UniSTSRGSC3.4
Celera149,288,147 - 9,288,574UniSTS
Cytogenetic Map14p22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001100564 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428575 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428577 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001428579 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250657 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250658 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006250661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008770022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017599168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_039091835 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC099384 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC082043 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC099076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH474022 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EV774847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FQ234112 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000014 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000003006   ⟹   ENSRNOP00000003006
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl149,131,433 - 9,187,790 (+)Ensembl
Rnor_6.0 Ensembl1410,786,399 - 10,828,106 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000102075   ⟹   ENSRNOP00000096414
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl149,146,146 - 9,187,790 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000106801   ⟹   ENSRNOP00000076578
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl149,130,336 - 9,187,790 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000109020   ⟹   ENSRNOP00000093056
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl149,146,114 - 9,187,790 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000119980   ⟹   ENSRNOP00000083208
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl149,131,799 - 9,187,790 (+)Ensembl
RefSeq Acc Id: NM_001100564   ⟹   NP_001094034
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,450,431 - 9,492,115 (+)NCBI
mRatBN7.2149,146,114 - 9,187,799 (+)NCBI
Rnor_6.01410,786,399 - 10,828,115 (+)NCBI
Rnor_5.01410,717,462 - 10,775,710 (+)NCBI
RGSC_v3.41410,398,080 - 10,439,960 (+)RGD
Celera149,254,128 - 9,295,581 (+)RGD
Sequence:
RefSeq Acc Id: XM_006250657   ⟹   XP_006250719
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,434,427 - 9,514,091 (+)NCBI
mRatBN7.2149,130,444 - 9,188,242 (+)NCBI
Rnor_6.01410,770,801 - 10,828,115 (+)NCBI
Rnor_5.01410,717,462 - 10,775,710 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250658   ⟹   XP_006250720
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,434,093 - 9,514,091 (+)NCBI
mRatBN7.2149,129,797 - 9,188,244 (+)NCBI
Rnor_6.01410,770,072 - 10,828,115 (+)NCBI
Rnor_5.01410,717,462 - 10,775,710 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250659   ⟹   XP_006250721
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,436,285 - 9,514,091 (+)NCBI
mRatBN7.2149,131,971 - 9,188,242 (+)NCBI
Rnor_6.01410,772,068 - 10,828,115 (+)NCBI
Rnor_5.01410,717,462 - 10,775,710 (+)NCBI
Sequence:
RefSeq Acc Id: XM_006250661   ⟹   XP_006250723
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,434,093 - 9,514,091 (+)NCBI
mRatBN7.2149,129,797 - 9,188,244 (+)NCBI
Rnor_6.01410,770,072 - 10,828,115 (+)NCBI
Rnor_5.01410,717,462 - 10,775,710 (+)NCBI
Sequence:
RefSeq Acc Id: XM_008770022   ⟹   XP_008768244
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,434,765 - 9,514,091 (+)NCBI
mRatBN7.2149,130,444 - 9,188,242 (+)NCBI
Rnor_6.01410,770,801 - 10,828,115 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017599168   ⟹   XP_017454657
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,436,285 - 9,514,091 (+)NCBI
mRatBN7.2149,131,971 - 9,188,242 (+)NCBI
Rnor_6.01410,772,068 - 10,828,115 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039091835   ⟹   XP_038947763
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8149,464,184 - 9,514,091 (+)NCBI
mRatBN7.2149,159,898 - 9,188,244 (+)NCBI
RefSeq Acc Id: NP_001094034   ⟸   NM_001100564
- UniProtKB: Q4FZV6 (UniProtKB/Swiss-Prot),   Q641Z1 (UniProtKB/Swiss-Prot),   A6K5Z8 (UniProtKB/TrEMBL),   A0A8L2Q0T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250720   ⟸   XM_006250658
- Peptide Label: isoform X2
- UniProtKB: Q4FZV6 (UniProtKB/Swiss-Prot),   Q641Z1 (UniProtKB/Swiss-Prot),   A6K5Z8 (UniProtKB/TrEMBL),   A0A8L2Q0T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250723   ⟸   XM_006250661
- Peptide Label: isoform X4
- UniProtKB: A0A8I6G8M1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250719   ⟸   XM_006250657
- Peptide Label: isoform X1
- UniProtKB: A0A8I5ZJ81 (UniProtKB/TrEMBL),   A0A8L2Q0T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006250721   ⟸   XM_006250659
- Peptide Label: isoform X2
- UniProtKB: Q4FZV6 (UniProtKB/Swiss-Prot),   Q641Z1 (UniProtKB/Swiss-Prot),   A6K5Z8 (UniProtKB/TrEMBL),   A0A8L2Q0T4 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_008768244   ⟸   XM_008770022
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_017454657   ⟸   XM_017599168
- Peptide Label: isoform X4
- UniProtKB: A0A8I6G8M1 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000003006   ⟸   ENSRNOT00000003006
RefSeq Acc Id: XP_038947763   ⟸   XM_039091835
- Peptide Label: isoform X5
- UniProtKB: A6K600 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000083208   ⟸   ENSRNOT00000119980
Ensembl Acc Id: ENSRNOP00000096414   ⟸   ENSRNOT00000102075
Ensembl Acc Id: ENSRNOP00000076578   ⟸   ENSRNOT00000106801
Ensembl Acc Id: ENSRNOP00000093056   ⟸   ENSRNOT00000109020
Protein Domains
CRC

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q641Z1-F1-model_v2 AlphaFold Q641Z1 1-749 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen


Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1311361 AgrOrtholog
BioCyc Gene G2FUF-16401 BioCyc
Ensembl Genes ENSRNOG00000002203 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000003006.6 UniProtKB/TrEMBL
  ENSRNOT00000102075.1 UniProtKB/TrEMBL
  ENSRNOT00000106801.1 UniProtKB/TrEMBL
  ENSRNOT00000109020.1 UniProtKB/TrEMBL
  ENSRNOT00000119980.1 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7131638 IMAGE-MGC_LOAD
  IMAGE:7441982 IMAGE-MGC_LOAD
InterPro CRC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Lin-54_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tesmin/TSO1-like_CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report rno:305171 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE MGC:116098 IMAGE-MGC_LOAD
  MGC:95188 IMAGE-MGC_LOAD
NCBI Gene 305171 ENTREZGENE
PANTHER PROTEIN LIN-54 HOMOLOG UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR12446 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam TCR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Lin54 PhenoGen
PROSITE CRC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx ENSRNOG00000002203 RatGTEx
SMART CXC UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A8I5ZJ81 ENTREZGENE, UniProtKB/TrEMBL
  A0A8I6AHW0_RAT UniProtKB/TrEMBL
  A0A8I6ATA6_RAT UniProtKB/TrEMBL
  A0A8I6G8M1 ENTREZGENE, UniProtKB/TrEMBL
  A0A8L2Q0T4 ENTREZGENE, UniProtKB/TrEMBL
  A6K5Z8 ENTREZGENE, UniProtKB/TrEMBL
  A6K600 ENTREZGENE, UniProtKB/TrEMBL
  LIN54_RAT UniProtKB/Swiss-Prot
  Q4FZV6 ENTREZGENE
  Q641Z1 ENTREZGENE
UniProt Secondary Q4FZV6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2014-07-23 Lin54  lin-54 DREAM MuvB core complex component  Lin54  lin-54 homolog (C. elegans)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-09-12 Lin54  lin-54 homolog (C. elegans)  RGD1311361  similar to hypothetical protein  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 RGD1311361  similar to hypothetical protein  RGD1311361_predicted  similar to hypothetical protein (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-20 RGD1311361_predicted  similar to hypothetical protein (predicted)  LOC305171_predicted    Symbol and Name status set to approved 1331353 APPROVED
2005-01-12 LOC305171_predicted  similar to hypothetical protein (predicted)      Symbol and Name status set to provisional 70820 PROVISIONAL