Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Lin54 | Rat | 1,2-dimethylhydrazine | decreases expression | ISO | Lin54 (Mus musculus) | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of LIN54 mRNA | CTD | PMID:22206623 | Lin54 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Lin54 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of LIN54 mRNA | CTD | PMID:21570461 | Lin54 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | increases expression | ISO | Lin54 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in increased expression of LIN54 mRNA | CTD | PMID:19465110 | Lin54 | Rat | 3,4-methylenedioxymethamphetamine | increases expression | ISO | Lin54 (Mus musculus) | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of LIN54 mRNA | CTD | PMID:20188158 | Lin54 | Rat | acrolein | multiple interactions | ISO | LIN54 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of LIN54 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of LIN54 mRNA | CTD | PMID:32699268 | Lin54 | Rat | acrylamide | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Acrylamide results in increased expression of LIN54 mRNA | CTD | PMID:32763439 | Lin54 | Rat | aflatoxin B1 | increases methylation | ISO | LIN54 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased methylation of LIN54 gene | CTD | PMID:28458013 | Lin54 | Rat | alpha-pinene | multiple interactions | ISO | LIN54 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of LIN54 mRNA and [Air Pollutants results in increased abundance of [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone]] which results in increased expression of LIN54 mRNA | CTD | PMID:32699268 | Lin54 | Rat | arsenite(3-) | multiple interactions | ISO | LIN54 (Homo sapiens) | 6480464 | arsenite inhibits the reaction [G3BP1 protein binds to LIN54 mRNA] | CTD | PMID:32406909 | Lin54 | Rat | benzo[a]pyrene | decreases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of LIN54 mRNA | CTD | PMID:20106945 and PMID:21632981 | Lin54 | Rat | benzo[a]pyrene | decreases methylation | ISO | LIN54 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased methylation of LIN54 5' UTR | CTD | PMID:27901495 | Lin54 | Rat | benzo[a]pyrene | affects methylation | ISO | LIN54 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of LIN54 intron | CTD | PMID:30157460 | Lin54 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of LIN54 mRNA | CTD | PMID:25181051 more ... | Lin54 | Rat | cadmium dichloride | decreases methylation | EXP | | 6480464 | Cadmium Chloride results in decreased methylation of LIN54 promoter | CTD | PMID:22457795 | Lin54 | Rat | cadmium dichloride | increases expression | EXP | | 6480464 | Cadmium Chloride results in increased expression of LIN54 mRNA | CTD | PMID:33453195 | Lin54 | Rat | caffeine | decreases phosphorylation | ISO | LIN54 (Homo sapiens) | 6480464 | Caffeine results in decreased phosphorylation of LIN54 protein | CTD | PMID:35688186 | Lin54 | Rat | cisplatin | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of LIN54 mRNA | CTD | PMID:27594783 | Lin54 | Rat | cobalt dichloride | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | cobaltous chloride results in increased expression of LIN54 mRNA | CTD | PMID:19320972 | Lin54 | Rat | cobalt dichloride | increases expression | EXP | | 6480464 | cobaltous chloride results in increased expression of LIN54 mRNA | CTD | PMID:24386269 | Lin54 | Rat | copper(II) sulfate | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Copper Sulfate results in increased expression of LIN54 mRNA | CTD | PMID:19549813 | Lin54 | Rat | cyclosporin A | decreases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of LIN54 mRNA | CTD | PMID:25562108 | Lin54 | Rat | doxorubicin | decreases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Doxorubicin results in decreased expression of LIN54 mRNA | CTD | PMID:29803840 | Lin54 | Rat | endosulfan | increases expression | EXP | | 6480464 | Endosulfan results in increased expression of LIN54 mRNA | CTD | PMID:29391264 | Lin54 | Rat | flutamide | increases expression | EXP | | 6480464 | Flutamide results in increased expression of LIN54 mRNA | CTD | PMID:24136188 and PMID:24793618 | Lin54 | Rat | FR900359 | affects phosphorylation | ISO | LIN54 (Homo sapiens) | 6480464 | FR900359 affects the phosphorylation of LIN54 protein | CTD | PMID:37730182 | Lin54 | Rat | gentamycin | increases expression | EXP | | 6480464 | Gentamicins results in increased expression of LIN54 mRNA | CTD | PMID:33387578 | Lin54 | Rat | hydrogen peroxide | multiple interactions | ISO | Lin54 (Mus musculus) | 6480464 | [Hydrogen Peroxide co-treated with N-(oxo-5 more ... | CTD | PMID:31494107 | Lin54 | Rat | leflunomide | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | leflunomide results in increased expression of LIN54 mRNA | CTD | PMID:28988120 | Lin54 | Rat | lipopolysaccharide | multiple interactions | ISO | LIN54 (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with resveratrol] results in decreased expression of LIN54 mRNA | CTD | PMID:26667767 | Lin54 | Rat | methamphetamine | decreases expression | ISO | Lin54 (Mus musculus) | 6480464 | Methamphetamine results in decreased expression of LIN54 mRNA | CTD | PMID:26307267 | Lin54 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of LIN54 gene | CTD | PMID:35440735 | Lin54 | Rat | methyl methanesulfonate | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Methyl Methanesulfonate results in increased expression of LIN54 mRNA | CTD | PMID:23649840 | Lin54 | Rat | monosodium L-glutamate | decreases expression | ISO | Lin54 (Mus musculus) | 6480464 | Sodium Glutamate results in decreased expression of LIN54 mRNA | CTD | PMID:22078008 | Lin54 | Rat | oxaliplatin | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of LIN54 mRNA | CTD | PMID:25729387 | Lin54 | Rat | ozone | multiple interactions | ISO | LIN54 (Homo sapiens) | 6480464 | [Acrolein co-treated with methacrylaldehyde co-treated with alpha-pinene co-treated with Ozone] results in increased expression of LIN54 mRNA more ... | CTD | PMID:32699268 | Lin54 | Rat | paracetamol | affects expression | ISO | Lin54 (Mus musculus) | 6480464 | Acetaminophen affects the expression of LIN54 mRNA | CTD | PMID:17562736 | Lin54 | Rat | paracetamol | increases expression | EXP | | 6480464 | Acetaminophen results in increased expression of LIN54 mRNA | CTD | PMID:33387578 | Lin54 | Rat | phenobarbital | affects expression | ISO | Lin54 (Mus musculus) | 6480464 | Phenobarbital affects the expression of LIN54 mRNA | CTD | PMID:23091169 | Lin54 | Rat | resorcinol | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | resorcinol results in increased expression of LIN54 mRNA | CTD | PMID:22623647 | Lin54 | Rat | resveratrol | multiple interactions | ISO | LIN54 (Homo sapiens) | 6480464 | [Lipopolysaccharides co-treated with resveratrol] results in decreased expression of LIN54 mRNA | CTD | PMID:26667767 | Lin54 | Rat | sodium arsenite | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of LIN54 mRNA | CTD | PMID:38568856 | Lin54 | Rat | sodium dichromate | affects expression | EXP | | 6480464 | sodium bichromate affects the expression of LIN54 mRNA | CTD | PMID:22110744 | Lin54 | Rat | sunitinib | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of LIN54 mRNA | CTD | PMID:31533062 | Lin54 | Rat | tetrachloromethane | decreases expression | ISO | Lin54 (Mus musculus) | 6480464 | Carbon Tetrachloride results in decreased expression of LIN54 mRNA | CTD | PMID:17484886 | Lin54 | Rat | tetrachloromethane | increases expression | ISO | Lin54 (Mus musculus) | 6480464 | Carbon Tetrachloride results in increased expression of LIN54 mRNA | CTD | PMID:31919559 | Lin54 | Rat | thioacetamide | increases expression | EXP | | 6480464 | Thioacetamide results in increased expression of LIN54 mRNA | CTD | PMID:34492290 | Lin54 | Rat | thiram | increases expression | ISO | LIN54 (Homo sapiens) | 6480464 | Thiram results in increased expression of LIN54 mRNA | CTD | PMID:38568856 | Lin54 | Rat | titanium dioxide | decreases expression | ISO | Lin54 (Mus musculus) | 6480464 | titanium dioxide results in decreased expression of LIN54 mRNA | CTD | PMID:29264374 | Lin54 | Rat | titanium dioxide | increases methylation | ISO | Lin54 (Mus musculus) | 6480464 | titanium dioxide results in increased methylation of LIN54 promoter | CTD | PMID:35295148 | Lin54 | Rat | topotecan | multiple interactions | EXP | | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of LIN54 mRNA | CTD | PMID:25729387 | Lin54 | Rat | trichloroethene | increases methylation | EXP | | 6480464 | Trichloroethylene results in increased methylation of LIN54 gene | CTD | PMID:27618143 | Lin54 | Rat | triphenyl phosphate | increases expression | EXP | | 6480464 | triphenyl phosphate results in increased expression of LIN54 mRNA | CTD | PMID:30589522 | Lin54 | Rat | triptonide | increases expression | ISO | Lin54 (Mus musculus) | 6480464 | triptonide results in increased expression of LIN54 mRNA | CTD | PMID:33045310 | Lin54 | Rat | troglitazone | decreases expression | ISO | Lin54 (Mus musculus) | 6480464 | troglitazone results in decreased expression of LIN54 mRNA | CTD | PMID:28973697 | Lin54 | Rat | trovafloxacin | decreases expression | ISO | Lin54 (Mus musculus) | 6480464 | trovafloxacin results in decreased expression of LIN54 mRNA | CTD | PMID:35537566 | |