C2cd2l (C2CD2-like) - Rat Genome Database

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Gene: C2cd2l (C2CD2-like) Rattus norvegicus
Analyze
Symbol: C2cd2l
Name: C2CD2-like
RGD ID: 1310281
Description: Predicted to enable insulin binding activity; phosphatidylinositol binding activity; and phosphatidylinositol transfer activity. Predicted to be involved in positive regulation of insulin secretion involved in cellular response to glucose stimulus. Predicted to be located in cortical endoplasmic reticulum; endoplasmic reticulum-plasma membrane contact site; and membrane. Predicted to colocalize with cytoplasmic side of apical plasma membrane. Orthologous to human C2CD2L (C2CD2 like); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 2,4-dinitrotoluene; 2,6-dinitrotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: C2 calcium-dependent domain containing 2-like; C2 domain-containing protein 2-like; LOC300666; phospholipid transfer protein C2CD2L; Tmem24; transmembrane protein 24
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Black Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,544,887 - 53,557,127 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl853,544,892 - 53,555,153 (-)EnsemblGRCr8
mRatBN7.2844,648,074 - 44,658,856 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,648,079 - 44,658,340 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx850,143,991 - 50,154,257 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,422,710 - 48,432,974 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,293,079 - 46,303,345 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,641,792 - 48,652,119 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,641,801 - 48,652,071 (-)Ensemblrn6Rnor6.0
Rnor_5.0847,259,701 - 47,269,990 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4847,288,755 - 47,299,021 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera844,234,307 - 44,244,573 (-)NCBICelera
RGSC_v3.1847,297,520 - 47,307,787 (-)NCBI
Cytogenetic Map8q22NCBI
JBrowse:




Disease Annotations     Click to see Annotation Detail View
RASopathy  (ISO)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. GOA pipeline RGD automated data pipeline
3. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:12477932   PMID:24012759   PMID:28209843  


Genomics

Comparative Map Data
C2cd2l
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8853,544,887 - 53,557,127 (-)NCBIGRCr8GRCr8GRCr8
GRCr8 Ensembl853,544,892 - 53,555,153 (-)EnsemblGRCr8
mRatBN7.2844,648,074 - 44,658,856 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl844,648,079 - 44,658,340 (-)EnsemblmRatBN7.2
UTH_Rnor_SHR_Utx850,143,991 - 50,154,257 (-)NCBIUTH_Rnor_SHR_UtxUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0848,422,710 - 48,432,974 (-)NCBIUTH_Rnor_SHRSP_BbbUtx_1.0UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0846,293,079 - 46,303,345 (-)NCBIUTH_Rnor_WKY_Bbb_1.0UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0848,641,792 - 48,652,119 (-)NCBIRnor_6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl848,641,801 - 48,652,071 (-)Ensemblrn6Rnor6.0
Rnor_5.0847,259,701 - 47,269,990 (-)NCBIRnor_5.0Rnor_5.0rn5
RGSC_v3.4847,288,755 - 47,299,021 (-)NCBIRGSC_v3.4RGSC_v3.4rn4
Celera844,234,307 - 44,244,573 (-)NCBICelera
RGSC_v3.1847,297,520 - 47,307,787 (-)NCBI
Cytogenetic Map8q22NCBI
C2CD2L
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh3811119,102,249 - 119,118,544 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl11119,102,198 - 119,118,544 (+)Ensemblhg38GRCh38
GRCh3711118,977,460 - 118,989,254 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3611118,483,303 - 118,493,037 (+)NCBIBuild 36Build 36hg18NCBI36
Build 3411118,483,302 - 118,493,036NCBI
Celera11116,135,506 - 116,145,233 (+)NCBICelera
Cytogenetic Map11q23.3NCBI
HuRef11114,917,539 - 114,927,267 (+)NCBIHuRef
CHM1_111118,864,397 - 118,874,130 (+)NCBICHM1_1
T2T-CHM13v2.011119,127,131 - 119,138,918 (+)NCBIT2T-CHM13v2.0
C2cd2l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39944,220,534 - 44,231,579 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl944,220,534 - 44,231,582 (-)EnsemblGRCm39 EnsemblGRCm39
GRCm38944,309,237 - 44,320,282 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl944,309,237 - 44,320,285 (-)Ensemblmm10GRCm38
MGSCv37944,117,320 - 44,128,365 (-)NCBIMGSCv37MGSCv37mm9NCBIm37
MGSCv36944,061,210 - 44,071,141 (-)NCBIMGSCv36mm8
Celera941,563,858 - 41,575,016 (-)NCBICelera
Cytogenetic Map9A5.2NCBI
cM Map924.84NCBI
C2cd2l
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541220,223,890 - 20,236,709 (+)Ensembl
ChiLan1.0NW_00495541220,214,915 - 20,232,260 (+)NCBIChiLan1.0ChiLan1.0
C2CD2L
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v29119,811,525 - 119,821,896 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan111120,915,226 - 120,925,593 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v011113,944,939 - 113,955,296 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.111117,874,533 - 117,884,442 (+)NCBIPanPan1.1PanPan1.1panPan2
PanPan1.1 Ensembl11117,875,077 - 117,883,581 (+)EnsemblpanPan2panpan1.1
C2CD2L
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1514,746,613 - 14,755,952 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl514,747,208 - 14,755,925 (-)EnsemblcanFam3CanFam3.1
Dog10K_Boxer_Tasha514,799,654 - 14,808,590 (-)NCBIDog10K_Boxer_TashaDog10K_Boxer_Tasha
ROS_Cfam_1.0514,689,970 - 14,698,925 (-)NCBIROS_Cfam_1.0ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl514,689,974 - 14,699,207 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1514,828,022 - 14,836,974 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0514,732,039 - 14,740,991 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0514,772,426 - 14,781,368 (-)NCBIUU_Cfam_GSD_1.0UU_Cfam_GSD_1.0
C2cd2l
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947101,132,837 - 101,146,771 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365424,058,669 - 4,069,002 (+)EnsemblSpeTri2.0 Ensembl
SpeTri2.0NW_0049365424,058,945 - 4,068,187 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
C2CD2L
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl946,321,817 - 46,331,078 (+)EnsemblsusScr11Sscrofa11.1
Sscrofa11.1946,321,761 - 46,331,078 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2951,356,903 - 51,366,225 (+)NCBISscrofa10.2Sscrofa10.2susScr3
C2CD2L
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,475,073 - 110,490,431 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,480,738 - 110,491,508 (+)EnsemblChlSab1.1 EnsemblchlSab2Vervet-AGM
Vero_WHO_p1.0NW_02366604315,543,655 - 15,559,150 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
C2cd2l
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462478414,489,478 - 14,501,175 (+)EnsemblHetGla_female_1.0 EnsemblhetGla2HetGla_female_1.0 Ensembl
HetGla 1.0NW_00462478414,489,638 - 14,498,617 (+)NCBIHetGla 1.0HetGla 1.0hetGla2
C2cd2l
(Rattus rattus - black rat)
Black Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rrattus_CSIRO_v1838,867,573 - 38,878,047 (-)NCBIRrattus_CSIRO_v1

Variants

.
Variants in C2cd2l
99 total Variants
miRNA Target Status (No longer updated)

Predicted Target Of
Summary Value
Count of predictions:143
Count of miRNA genes:104
Interacting mature miRNAs:123
Transcripts:ENSRNOT00000030745
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCr8)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2313057Bss76Bone structure and strength QTL 7630.0001tibia size trait (VT:0100001)tibia midshaft cross-sectional area (CMO:0001717)83910625891341052Rat
1298065Scl16Serum cholesterol level QTL 163.8blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)83975280384752803Rat
2317030Wbc5White blood cell count QTL 53.210.005leukocyte quantity (VT:0000217)white blood cell count (CMO:0000027)81699464261994642Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)849849908118871671Rat
2313067Bss77Bone structure and strength QTL 773.10.0001tibia size trait (VT:0100001)tibia midshaft endosteal cross-sectional area (CMO:0001716)83910625891341052Rat
1578769Uae31Urinary albumin excretion QTL 313.30.001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)839106363103375781Rat
2317032Ginf2Gastrointestinal inflammation QTL 23.210.005liver integrity trait (VT:0010547)liver granuloma severity score (CMO:0002157)81296416557964165Rat
2301416Bp315Blood pressure QTL 3150.008arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)81595227960952279Rat
1298079Activ2Activity QTL 29.50.000001voluntary movement trait (VT:0003491)rearing measurement (CMO:0001515)85076395195763951Rat
11556286Cm81Cardiac mass QTL 810.01heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)83910625884106258Rat
2317036Livw3Liver weight QTL 32.430.01liver mass (VT:0003402)liver weight to body weight ratio (CMO:0000633)81296416557964165Rat
70161Bp62Blood pressure QTL 622.90.001arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)85158969999045312Rat
12880023Bw184Body weight QTL 1840.001body mass (VT:0001259)body weight (CMO:0000012)81038254055382540Rat
1578765Klgr1Kidney lesion grade QTL 13.30.0001kidney morphology trait (VT:0002135)organ lesion measurement (CMO:0000677)839106363103375781Rat
5684993Bmd84Bone mineral density QTL 844.1tibia mineral mass (VT:1000283)bone mineral content (CMO:0001554)85158969958991895Rat
12880028Cm103Cardiac mass QTL 1030.02heart left ventricle mass (VT:0007031)heart left ventricle weight to body weight ratio (CMO:0000530)81038254055382540Rat
2317051Aia18Adjuvant induced arthritis QTL 182.42joint integrity trait (VT:0010548)left rear ankle joint diameter (CMO:0002149)81699464261994642Rat
61464Niddm11Non-insulin dependent diabetes mellitus QTL 113.10.001blood insulin amount (VT:0001560)plasma insulin level (CMO:0000342)84447792689477926Rat
2317048Ginf1Gastrointestinal inflammation QTL 13.520.005cecum mucosa thickness (VT:0010234)enterocolitis severity score (CMO:0002138)81296416557964165Rat
1578755Pur5Proteinuria QTL 53.30.0001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)839106258103375958Rat
12880025Cm102Cardiac mass QTL 1020.044heart mass (VT:0007028)heart wet weight to body weight ratio (CMO:0002408)81038254055382540Rat
2313088Bss75Bone structure and strength QTL 753.10.0001body length (VT:0001256)body length, nose to rump (CMO:0000079)83910625891341052Rat
1358896Bp262Blood pressure QTL 2622.89arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)835464071107982864Rat
2302278Gluco36Glucose level QTL 364.2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)83776085958991895Rat
731182Uae24Urinary albumin excretion QTL 246.4urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)84754141992541419Rat
12880044Am9Aortic mass QTL 90.007aorta mass (VT:0002845)aorta weight to aorta length to body weight ratio (CMO:0002722)81038254055382540Rat
631648Stl5Serum triglyceride level QTL 540.0003blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)83546407171842899Rat
724514Uae15Urinary albumin excretion QTL 152.9urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)83776085961459705Rat
61353Bp35Blood pressure QTL 350.001arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)83910625884106258Rat
631842Inf1Infertility severity QTL 14.10.001seminal gland mass (VT:0010524)seminal vesicle wet weight (CMO:0001603)83154366176543661Rat
737824Hcar10Hepatocarcinoma resistance QTL 102.9liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)84961020468373388Rat
1359033Bp273Blood pressure QTL 273arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625884106258Rat
1331769Rf39Renal function QTL 393.871urine output (VT:0003620)timed urine volume (CMO:0000260)850763951107970527Rat
61358Bp39Blood pressure QTL 392arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)84444783789447837Rat
1358906Bp253Blood pressure QTL 25340.0004arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)84961020494610204Rat
1358907Cm40Cardiac mass QTL 401.89heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)835464071107982864Rat
1598824Memor4Memory QTL 42.5exploratory behavior trait (VT:0010471)total horizontal distance resulting from voluntary locomotion in an experimental apparatus (CMO:0001443)81799386262252873Rat
1331744Bp217Blood pressure QTL 2173.398arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)83910625867378345Rat
2313046Bss78Bone structure and strength QTL 783.50.0001tibia strength trait (VT:1000284)tibia total energy absorbed before break (CMO:0001736)83910625891341052Rat
2316950Scl66Serum cholesterol level QTL 664.1blood cholesterol amount (VT:0000180)plasma total cholesterol level (CMO:0000585)839106363114525825Rat
1582254Kidm31Kidney mass QTL 313kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)84924517894245178Rat
724540Uae8Urinary albumin excretion QTL 85urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)839106258103375958Rat
1358892Kidm26Kidney mass QTL 263.69kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)835464071107982864Rat
1359021Bp271Blood pressure QTL 2711.8arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)83412590255607752Rat
631216Stl9Serum triglyceride level QTL 94.710.0001blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)85076395167219641Rat
1582243Bw66Body weight QTL 663.40.0048body mass (VT:0001259)body weight (CMO:0000012)84924517894245178Rat
61373Mcs4Mammary carcinoma susceptibility QTL 41.1mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)84447504389475043Rat

Markers in Region
RH144175  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2844,651,007 - 44,651,142 (+)MAPPERmRatBN7.2
Rnor_6.0848,644,732 - 48,644,866NCBIRnor6.0
Rnor_5.0847,262,635 - 47,262,769UniSTSRnor5.0
RGSC_v3.4847,291,689 - 47,291,823UniSTSRGSC3.4
Celera844,237,241 - 44,237,375UniSTS
RH 3.4 Map8426.6UniSTS
Cytogenetic Map8q22UniSTS
BF386203  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2844,653,676 - 44,653,860 (+)MAPPERmRatBN7.2
Rnor_6.0848,647,401 - 48,647,584NCBIRnor6.0
Rnor_5.0847,265,304 - 47,265,487UniSTSRnor5.0
RGSC_v3.4847,294,358 - 47,294,541UniSTSRGSC3.4
Celera844,239,910 - 44,240,093UniSTS
RH 3.4 Map8437.2UniSTS
Cytogenetic Map8q22UniSTS
BI279622  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2844,651,007 - 44,651,198 (+)MAPPERmRatBN7.2
Rnor_6.0848,644,732 - 48,644,922NCBIRnor6.0
Rnor_5.0847,262,635 - 47,262,825UniSTSRnor5.0
RGSC_v3.4847,291,689 - 47,291,879UniSTSRGSC3.4
Celera844,237,241 - 44,237,431UniSTS
RH 3.4 Map8436.8UniSTS
Cytogenetic Map8q22UniSTS


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
renal system
reproductive system
respiratory system
sensory system
visual system
16 12 67 162 91 90 59 92 59 6 356 192 11 141 81 92 31 17 17

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001011996 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433225 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433230 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433231 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001433233 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242918 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006242920 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_008766157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265109 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063265110 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC112557 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC085925 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH473975 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JAXUCZ010000008 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSRNOT00000030745   ⟹   ENSRNOP00000036065
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl853,544,892 - 53,555,153 (-)Ensembl
mRatBN7.2 Ensembl844,648,079 - 44,658,340 (-)Ensembl
Rnor_6.0 Ensembl848,641,801 - 48,652,064 (-)Ensembl
Ensembl Acc Id: ENSRNOT00000083490   ⟹   ENSRNOP00000072391
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8 Ensembl853,546,988 - 53,555,153 (-)Ensembl
mRatBN7.2 Ensembl844,650,754 - 44,658,340 (-)Ensembl
Rnor_6.0 Ensembl848,644,262 - 48,652,071 (-)Ensembl
RefSeq Acc Id: NM_001011996   ⟹   NP_001011996
RefSeq Status: VALIDATED
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,544,887 - 53,555,153 (-)NCBI
mRatBN7.2844,648,074 - 44,658,340 (-)NCBI
Rnor_6.0848,641,798 - 48,652,064 (-)NCBI
Rnor_5.0847,259,701 - 47,269,990 (-)NCBI
RGSC_v3.4847,288,755 - 47,299,021 (-)RGD
Celera844,234,307 - 44,244,573 (-)RGD
Sequence:
RefSeq Acc Id: XM_006242917   ⟹   XP_006242979
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,544,887 - 53,557,127 (-)NCBI
mRatBN7.2844,648,074 - 44,658,411 (-)NCBI
Rnor_6.0848,641,792 - 48,652,118 (-)NCBI
Rnor_5.0847,259,701 - 47,269,990 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242918   ⟹   XP_006242980
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,544,887 - 53,557,127 (-)NCBI
mRatBN7.2844,648,074 - 44,658,406 (-)NCBI
Rnor_6.0848,641,792 - 48,652,117 (-)NCBI
Rnor_5.0847,259,701 - 47,269,990 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242919   ⟹   XP_006242981
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,544,887 - 53,557,127 (-)NCBI
mRatBN7.2844,648,074 - 44,658,409 (-)NCBI
Rnor_6.0848,641,792 - 48,652,117 (-)NCBI
Rnor_5.0847,259,701 - 47,269,990 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006242920   ⟹   XP_006242982
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,547,772 - 53,557,127 (-)NCBI
mRatBN7.2844,650,949 - 44,658,856 (-)NCBI
Rnor_6.0848,644,683 - 48,652,119 (-)NCBI
Rnor_5.0847,259,701 - 47,269,990 (-)NCBI
Sequence:
RefSeq Acc Id: XM_063265107   ⟹   XP_063121177
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,545,741 - 53,557,127 (-)NCBI
RefSeq Acc Id: XM_063265108   ⟹   XP_063121178
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,547,772 - 53,557,127 (-)NCBI
RefSeq Acc Id: XM_063265109   ⟹   XP_063121179
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,547,772 - 53,557,127 (-)NCBI
RefSeq Acc Id: XM_063265110   ⟹   XP_063121180
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8853,547,772 - 53,557,127 (-)NCBI
RefSeq Acc Id: NP_001011996   ⟸   NM_001011996
- UniProtKB: Q5U2P5 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006242981   ⟸   XM_006242919
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006242980   ⟸   XM_006242918
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_006242979   ⟸   XM_006242917
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_006242982   ⟸   XM_006242920
- Peptide Label: isoform X5
- Sequence:
Ensembl Acc Id: ENSRNOP00000072391   ⟸   ENSRNOT00000083490
Ensembl Acc Id: ENSRNOP00000036065   ⟸   ENSRNOT00000030745
RefSeq Acc Id: XP_063121177   ⟸   XM_063265107
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063121180   ⟸   XM_063265110
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063121179   ⟸   XM_063265109
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063121178   ⟸   XM_063265108
- Peptide Label: isoform X6
Protein Domains
C2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q5U2P5-F1-model_v2 AlphaFold Q5U2P5 1-706 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13695895
Promoter ID:EPDNEW_R6412
Type:initiation region
Name:C2cd2l_1
Description:C2CD2-like
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0848,652,086 - 48,652,146EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1310281 AgrOrtholog
BioCyc Gene G2FUF-30727 BioCyc
Ensembl Genes ENSRNOG00000009719 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000030745 ENTREZGENE
  ENSRNOT00000030745.8 UniProtKB/TrEMBL
  ENSRNOT00000083490 ENTREZGENE
  ENSRNOT00000083490.3 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7109537 IMAGE-MGC_LOAD
InterPro C2_dom UniProtKB/TrEMBL
  C2_domain_sf UniProtKB/TrEMBL
  C2CD2/C2CD2L UniProtKB/TrEMBL
  SMP_C2CD2L UniProtKB/TrEMBL
KEGG Report rno:300666 UniProtKB/TrEMBL
MGC_CLONE MGC:94851 IMAGE-MGC_LOAD
NCBI Gene 300666 ENTREZGENE
PANTHER PHOSPHOLIPID TRANSFER PROTEIN C2CD2L UniProtKB/TrEMBL
  PTHR21119 UniProtKB/TrEMBL
Pfam PF00168 UniProtKB/TrEMBL
  SMP_C2CD2L UniProtKB/TrEMBL
PhenoGen C2cd2l PhenoGen
PROSITE PS50004 UniProtKB/TrEMBL
RatGTEx ENSRNOG00000009719 RatGTEx
Superfamily-SCOP SSF49562 UniProtKB/TrEMBL
UniProt A0A0G2K2V4 ENTREZGENE, UniProtKB/TrEMBL
  F7EUW3 ENTREZGENE, UniProtKB/TrEMBL
  Q5U2P5 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2013-01-29 C2cd2l  C2CD2-like  C2cd2l  C2 calcium-dependent domain containing 2-like  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2009-11-06 C2cd2l  C2 calcium-dependent domain containing 2-like  Tmem24  transmembrane protein 24  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-12-06 Tmem24  transmembrane protein 24  Tmem24_predicted  transmembrane protein 24 (predicted)  Symbol and Name updated 1559027 APPROVED
2005-01-12 Tmem24_predicted  transmembrane protein 24 (predicted)      Symbol and Name status set to approved 70820 APPROVED