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Gene: Ctdspl2 (CTD small phosphatase like 2) Rattus norvegicus

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Symbol:

Ctdspl2

Name:

CTD small phosphatase like 2

RGD ID:

1309219

Description:

Predicted to enable RNA polymerase II CTD heptapeptide repeat phosphatase activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to act upstream of or within negative regulation of BMP signaling pathway; positive regulation of protein export from nucleus; and protein dephosphorylation. Predicted to be located in nucleoplasm. Orthologous to human CTDSPL2 (CTD small phosphatase like 2); INTERACTS WITH 17beta-estradiol; 4,4'-sulfonyldiphenol; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2; CTD small phosphatase-like protein 2; CTDSP-like 2; LOC311368; RGD1309219; similar to hypothetical protein HSPC129

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	129,365,709 - 129,424,232 (+)	NCBI		GRCr8
mRatBN7.2	3	108,915,263 - 108,970,620 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	108,915,280 - 108,967,227 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	112,589,499 - 112,641,835 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	121,185,039 - 121,237,372 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	118,845,411 - 118,897,746 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	113,906,803 - 113,957,289 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	113,918,629 - 113,960,101 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	120,445,979 - 120,498,692 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	108,742,714 - 108,796,435 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	108,648,286 - 108,702,007 (+)	NCBI
Celera	3	107,814,236 - 107,864,724 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Bloom syndrome (ISO)

colorectal cancer (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,2-dichloroethane (ISO)

1,2-dimethylhydrazine (ISO)

17beta-estradiol (EXP,ISO)

2,2',4,4'-Tetrabromodiphenyl ether (ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4,6-tribromophenol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

4,4'-sulfonyldiphenol (EXP,ISO)

aflatoxin B1 (ISO)

Aflatoxin B2 alpha (ISO)

all-trans-retinoic acid (ISO)

aristolochic acid A (ISO)

arsenite(3-) (ISO)

arsenous acid (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[e]pyrene (ISO)

beta-lapachone (ISO)

bisphenol A (EXP,ISO)

bisphenol F (EXP)

bortezomib (ISO)

cisplatin (ISO)

copper(II) sulfate (ISO)

coumarin (ISO)

coumestrol (ISO)

cyclosporin A (ISO)

DDE (ISO)

decabromodiphenyl ether (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

dicrotophos (ISO)

dioxygen (ISO)

dorsomorphin (ISO)

doxorubicin (ISO)

Enterolactone (ISO)

ethyl methanesulfonate (ISO)

FR900359 (ISO)

fulvestrant (ISO)

gallic acid (ISO)

geldanamycin (ISO)

methapyrilene (ISO)

methyl methanesulfonate (ISO)

methylmercury chloride (ISO)

paracetamol (ISO)

perfluorooctanoic acid (ISO)

phenobarbital (ISO)

phenylmercury acetate (ISO)

quercitrin (ISO)

resveratrol (ISO)

SB 431542 (ISO)

succimer (ISO)

sulforaphane (ISO)

temozolomide (ISO)

thimerosal (ISO)

thioacetamide (EXP)

titanium dioxide (ISO)

trichostatin A (ISO)

triphenyl phosphate (ISO)

valproic acid (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

negative regulation of BMP signaling pathway (IEA,ISO)

positive regulation of protein export from nucleus (IEA,ISO)

protein dephosphorylation (ISO)

protein export from nucleus (IEA,ISO)

regulation of transcription by RNA polymerase II (IEA)

Cellular Component

membrane (IEA)

nucleoplasm (IEA,ISO)

nucleus (ISO)

Molecular Function

phosphoprotein phosphatase activity (IBA,IEA,ISO)

protein binding (ISO)

RNA polymerase II CTD heptapeptide repeat phosphatase activity (IEA,ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	GOA pipeline	RGD automated data pipeline
3.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions
4.	Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.	Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.

Additional References at PubMed

PMID:25100727	PMID:26920047

Genomics

Comparative Map Data

Ctdspl2
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	3	129,365,709 - 129,424,232 (+)	NCBI		GRCr8
mRatBN7.2	3	108,915,263 - 108,970,620 (+)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	3	108,915,280 - 108,967,227 (+)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	3	112,589,499 - 112,641,835 (+)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	3	121,185,039 - 121,237,372 (+)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	3	118,845,411 - 118,897,746 (+)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	3	113,906,803 - 113,957,289 (+)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	3	113,918,629 - 113,960,101 (+)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	3	120,445,979 - 120,498,692 (+)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	3	108,742,714 - 108,796,435 (+)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	3	108,648,286 - 108,702,007 (+)	NCBI
Celera	3	107,814,236 - 107,864,724 (+)	NCBI		Celera
Cytogenetic Map	3	q35	NCBI

CTDSPL2
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	15	44,427,629 - 44,529,038 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	15	44,427,622 - 44,529,038 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	15	44,719,827 - 44,821,236 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	15	42,506,871 - 42,606,722 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Celera	15	21,609,344 - 21,709,186 (+)	NCBI		Celera
Cytogenetic Map	15	q15.3-q21.1	NCBI
HuRef	15	21,542,511 - 21,642,657 (+)	NCBI		HuRef
CHM1_1	15	44,837,772 - 44,937,540 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	15	42,234,989 - 42,336,704 (+)	NCBI		T2T-CHM13v2.0

Ctdspl2
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	2	121,785,879 - 121,845,807 (+)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	2	121,786,482 - 121,844,123 (+)	Ensembl		GRCm39 Ensembl
GRCm38	2	121,955,398 - 122,015,326 (+)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	2	121,956,001 - 122,013,642 (+)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	2	121,782,189 - 121,839,322 (+)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	2	121,647,894 - 121,705,027 (+)	NCBI		MGSCv36	mm8
Celera	2	123,105,063 - 123,161,640 (+)	NCBI		Celera
Cytogenetic Map	2	E5	NCBI
cM Map	2	60.46	NCBI

Ctdspl2
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955416	10,970,492 - 11,046,179 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955416	10,970,487 - 11,046,179 (+)	NCBI	ChiLan1.0	ChiLan1.0

CTDSPL2
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	16	33,674,389 - 33,774,598 (+)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	15	37,837,417 - 37,940,172 (+)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	15	23,384,416 - 23,483,508 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	15	41,554,276 - 41,654,736 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	15	41,554,276 - 41,654,736 (+)	Ensembl	panpan1.1		panPan2

CTDSPL2
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	30	11,109,571 - 11,194,985 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	30	11,109,664 - 11,193,534 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	30	11,166,102 - 11,254,634 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	30	11,245,681 - 11,334,277 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	30	11,245,772 - 11,334,259 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	30	11,152,895 - 11,241,371 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	30	11,276,652 - 11,363,904 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	30	11,395,449 - 11,483,617 (+)	NCBI		UU_Cfam_GSD_1.0

Ctdspl2
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024408640	89,577,496 - 89,657,911 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936471	7,425,590 - 7,503,980 (+)	Ensembl	SpeTri2.0	SpeTri2.0 Ensembl
SpeTri2.0	NW_004936471	7,425,543 - 7,502,299 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

CTDSPL2
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	1	127,028,887 - 127,125,392 (-)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	1	127,029,445 - 127,125,747 (-)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	1	141,621,919 - 141,627,665 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

CTDSPL2
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	26	38,516,044 - 38,626,963 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	26	38,519,094 - 38,627,099 (-)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666048	102,416,240 - 102,525,619 (+)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Ctdspl2
(Heterocephalus glaber - naked mole-rat)

Naked Mole-Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla 1.0	NW_004624804	11,703,529 - 11,781,542 (-)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Ctdspl2
442 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	35
Count of miRNA genes:	29
Interacting mature miRNAs:	35
Transcripts:	ENSRNOT00000037168
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2312673	Scl63	Serum cholesterol level QTL 63		0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	3	98535255	168026850	Rat
2301414	Kidm37	Kidney mass QTL 37		0.001	kidney mass (VT:0002707)	both kidneys wet weight to body weight ratio (CMO:0000340)	3	70653097	121056321	Rat
2302373	Gluco39	Glucose level QTL 39	5.01		blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	3	98535386	161695835	Rat
1582238	Bw68	Body weight QTL 68	3.2	0.0064	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582239	Epfw1	Epididymal fat weight QTL 1	4.5	0.0006	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	3	53184593	115665732	Rat
70216	Cm14	Cardiac mass QTL 14	2.1		heart mass (VT:0007028)	heart wet weight (CMO:0000069)	3	31172320	163586636	Rat
2292591	Esta4	Estrogen-induced thymic atrophy QTL 4			thymus mass (VT:0004954)	thymus wet weight (CMO:0000855)	3	47233211	147415807	Rat
1358362	Srcrt2	Stress Responsive Cort QTL 2	2.78		blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	3	38192233	133483320	Rat
1582216	Bw65	Body weight QTL 65	6.3		body mass (VT:0001259)	body weight (CMO:0000012)	3	102200529	115665732	Rat
737818	Hcar12	Hepatocarcinoma resistance QTL 12	2.6		liver integrity trait (VT:0010547)	volume of individual liver tumorous lesion (CMO:0001078)	3	29463235	118376539	Rat
1582218	Bw74	Body weight QTL 74	3.9	0.0021	body mass (VT:0001259)	body weight (CMO:0000012)	3	53184593	115665732	Rat
1582219	Bw63	Body weight QTL 63	3.8	0.001	body mass (VT:0001259)	body weight (CMO:0000012)	3	96127817	115665732	Rat
1582221	Kidm30	Kidney mass QTL 30	3.5	0.0008	kidney mass (VT:0002707)	both kidneys wet weight (CMO:0000085)	3	64655305	115665732	Rat
1581568	Rf53	Renal function QTL 53			urine total protein amount (VT:0000032)	urine protein excretion rate to body weight ratio (CMO:0001099)	3	56395968	161299569	Rat
1582210	Bw71	Body weight QTL 71	3.3	0.0012	body mass (VT:0001259)	body weight (CMO:0000012)	3	64655305	115665732	Rat
7387306	Bw124	Body weight QTL 124	3.2	0.0003	body mass (VT:0001259)	body weight (CMO:0000012)	3	84091273	129091273	Rat
1300111	Rf12	Renal function QTL 12	3.78		renal blood flow trait (VT:2000006)	absolute change in renal blood flow rate (CMO:0001168)	3	61017749	121056321	Rat
724523	Tsu1	Thymus enlargement suppressive QTL 1	3.84		thymus mass (VT:0004954)	thymus weight to body weight ratio (CMO:0000612)	3	50437504	115638231	Rat
1600376	Arunc5	Aerobic running capacity QTL 5		0.21	exercise endurance trait (VT:0002332)	maximum distance run on treadmill (CMO:0001406)	3	73376539	118376539	Rat
8694437	Bw167	Body weight QTL 167	22.46	0.001	retroperitoneal fat pad mass (VT:0010430)	retroperitoneal fat pad weight to body weight ratio (CMO:0000635)	3	91797474	136797474	Rat
2302273	Gluco35	Glucose level QTL 35	5.3	0.001	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	80800231	114297550	Rat
8662816	Vetf4	Vascular elastic tissue fragility QTL 4	4		renal artery integrity trait (VT:0010642)	number of ruptures of the internal elastic lamina of the renal arteries (CMO:0002563)	3	59242096	157323038	Rat
1559282	Emca5	Estrogen-induced mammary cancer QTL 5	3.9		mammary gland integrity trait (VT:0010552)	percentage of study population developing mammary tumors during a period of time (CMO:0000948)	3	43827364	169034231	Rat
1581503	Cm58	Cardiac mass QTL 58	2.7	0.05	heart left ventricle mass (VT:0007031)	heart left ventricle weight to body weight ratio (CMO:0000530)	3	43827364	121056321	Rat
1354611	Despr2	Despair related QTL 2	3.03	0.0028	locomotor behavior trait (VT:0001392)	amount of time spent in voluntary immobility (CMO:0001043)	3	97084464	142084464	Rat
2292613	Ept16	Estrogen-induced pituitary tumorigenesis QTL 16	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
631649	Bp123	Blood pressure QTL 123	3.2		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	3	89772419	134772419	Rat
631841	Niddm39	Non-insulin dependent diabetes mellitus QTL 39	3.36		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	94856903	159898684	Rat
619618	Rf3	Renal disease susceptibility QTL 3	6.5	0.001	urine albumin amount (VT:0002871)	urine albumin excretion rate to body weight ratio (CMO:0001270)	3	107693393	152693393	Rat
12879848	Bw181	Body weght QTL 181		0.015	body mass (VT:0001259)	body weight (CMO:0000012)	3	70348525	121056321	Rat
2312659	Slep7	Serum leptin concentration QTL 7		0.001	blood leptin amount (VT:0005667)	serum leptin level (CMO:0000780)	3	98535255	168026850	Rat
2301971	Cm71	Cardiac mass QTL 71	4.63		heart left ventricle mass (VT:0007031)	heart left ventricle weight (CMO:0000776)	3	41874578	155617519	Rat
2301970	Bw81	Body weight QTL 81	5.19		body mass (VT:0001259)	body weight (CMO:0000012)	3	41874578	155617519	Rat
1358885	Bp251	Blood pressure QTL 251	3.8		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
1581546	Pur13	Proteinuria QTL 13	2.93	0.0335	urine total protein amount (VT:0000032)	urine protein excretion rate (CMO:0000759)	3	78196190	146592722	Rat
631665	Bw8	Body weight QTL 8	5.5		body mass (VT:0001259)	body weight (CMO:0000012)	3	50437042	119183768	Rat
1358888	Bp264	Blood pressure QTL 264	4.43		arterial blood pressure trait (VT:2000000)	mean arterial blood pressure (CMO:0000009)	3	14489145	121056321	Rat
2312670	Bw94	Body weight QTL 94		0.01	inguinal fat pad mass (VT:0010424)	inguinal fat pad weight to body weight ratio (CMO:0001253)	3	98535255	168026850	Rat
2293087	Iddm27	Insulin dependent diabetes mellitus QTL 27	2.68		blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	3	97551417	147415807	Rat
1358186	Ept2	Estrogen-induced pituitary tumorigenesis QTL 2	8.3		pituitary gland mass (VT:0010496)	pituitary gland wet weight (CMO:0000853)	3	47233430	110362260	Rat
724532	Cm17	Cardiac mass QTL 17	2		heart mass (VT:0007028)	calculated heart weight (CMO:0000073)	3	95735366	140735366	Rat

Markers in Region

BF397433

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	108,965,203 - 108,965,365 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	113,956,520 - 113,956,681	NCBI	Rnor6.0
Rnor_5.0	3	120,496,036 - 120,496,197	UniSTS	Rnor5.0
RGSC_v3.4	3	108,795,666 - 108,795,827	UniSTS	RGSC3.4
Celera	3	107,863,955 - 107,864,116	UniSTS
RH 3.4 Map	3	954.1	UniSTS
Cytogenetic Map	3	q35	UniSTS

C87309

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	3	108,965,959 - 108,966,207 (+)	MAPPER	mRatBN7.2
Rnor_6.0	3	113,957,276 - 113,957,523	NCBI	Rnor6.0
Rnor_5.0	3	120,496,792 - 120,497,039	UniSTS	Rnor5.0
RGSC_v3.4	3	108,796,422 - 108,796,669	UniSTS	RGSC3.4
Celera	3	107,864,711 - 107,864,958	UniSTS
Cytogenetic Map	3	q35	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001014048	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001409574	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_039104968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283736	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283737	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_063283738	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064620	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064621	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064622	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064623	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064624	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064625	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_010064626	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC083672	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473949	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000003	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000037168 ⟹ ENSRNOP00000033786

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	108,915,473 - 108,965,972 (+)	Ensembl
Rnor_6.0 Ensembl	3	113,918,651 - 113,957,195 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000078978 ⟹ ENSRNOP00000068736

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	108,915,280 - 108,967,227 (+)	Ensembl
Rnor_6.0 Ensembl	3	113,918,629 - 113,960,101 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000106655 ⟹ ENSRNOP00000093407

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	108,915,280 - 108,967,227 (+)	Ensembl

Ensembl Acc Id:

ENSRNOT00000118841 ⟹ ENSRNOP00000083281

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	3	108,915,280 - 108,967,227 (+)	Ensembl

RefSeq Acc Id:

NM_001014048 ⟹ NP_001014070

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,369,127 - 129,424,232 (+)	NCBI
mRatBN7.2	3	108,915,451 - 108,970,620 (+)	NCBI
Rnor_6.0	3	113,906,803 - 113,957,289 (+)	NCBI
Rnor_5.0	3	120,445,979 - 120,498,692 (+)	NCBI
RGSC_v3.4	3	108,742,714 - 108,796,435 (+)	RGD
Celera	3	107,814,236 - 107,864,724 (+)	RGD

Sequence:

show sequence

GCCGGGATCTCCTCCCCTTCTCAAGCCGAGCCTTCAGCGGTTCCAGCACGTCCGTAGGCATGCA
CTGTTGGCGCCTTGTTTACATGTGGCACCCATAAAAGATGAAGCTGAGAACACGGAAGGCTTCT
CAGCAGTCCAGTCCAATCCAAACACAGCGCACTGCCAGAGCAAAAAGGAAATACTCAGAGGTTG
ATGATAGCTTGCCTTCAGGAGGAGAAAAACCATCCAAGAATGAAACCGGCTTATTGTCTTCAAT
TAAAAAGTTCATTAAAGGAAGCACGCCCAAGGAAGAGAGAGAAAATCCTTCAAAACGGAGTAGA
ATTGAACGAGATATAGATAATAATTTAATCACATCAACACCAAGAACTGGAGAAAAGCCTGACA
AACAGTTGTCTCGAGTAAGACGGAAAAGTCCAGTCAATGGAGAAGCTGGTAGTTATGAAATGAC
AAATCAACATATAAAACAAAATGGAAAATTAGAAGATAATCCTTGTTCAGGTAGTCCTCCAAGG
ACTACATTGTTGGGGACCATATTTTCGCCAGTCTTCAACTTTTTTTCACCAGCAAATAAAAATG
GAACGTCAGGTTCAGATTCCCCAGGACAGGCTGTGGAAGCTGAGGAGATAGTGAAACAACTTGA
CATGGAACAGGTGGATGAAATCACTACCAGTACTACGTCAGCTAATGGAGCGGCCTACTCAAAT
CAAGCAGTTCAAGTGAGGCCATCACTCAATAATGGTTTGGAAGAAGCAGAAGAAACAGTTACTC
GGGATATCCCACCCCTTACAGCACCAGTAGCTCCCGAGAGTGGTTACTCATCAGCTCATGCAGA
GGCCACCTATGAGGAAGACTGGGAAGTATTTGACCCCTATTATTTCATCAAACATGTTCCGCCT
CTGACAGAAGAACAACTAAATAGGAAACCTGCTCTTCCTCTGAAAACGAGAAGCACACCGGAGT
TCTCCCTGGTCTTAGATCTGGATGAAACGCTAGTGCACTGCAGTCTGAATGAGCTGGAAGATGC
AGCACTAACTTTTCCAGTCCTTTTCCAAGATGTCATTTATCAGGTTTATGTGAGATTAAGACCA
TTCTTCAGGGAATTCCTGGAGCGAATGTCTCAGATGTATGAGATCATTCTTTTTACTGCTTCTA
AGAAGGTGTATGCAGACAAGTTACTGAACATACTAGACCCTAAAAAGCAACTGGTCAGGCACCG
GCTTTTCCGTGAACATTGTGTTTGTGTACAAGGAAATTATATAAAGGACTTAAATATCCTTGGA
AGAGACCTTTCTAAAACTATAATAATTGACAACTCACCACAAGCCTTTGCCTATCAGCTTTCTA
ATGGAATCCCTATAGAAAGCTGGTTTATGGATAAAAATGACAATGAACTCCTAAAATTGATTCC
ATTTCTGGAGAAGCTTGTAGAACTGAATGAAGATGTCCGGCCTCACATCAGAGACAGATTTCGA
TTGCATGATTTGCTGCCCCCAGATTAAGTTCAGAGACTTGTCAGATCACTGAAGGGGGGAGAGA
ATGCAGGACCCTTTTGGACTAAGACAAAAACATTGCCATTACTGTTGAAATTTTGCAAAAAAAA
AAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

NM_001409574 ⟹ NP_001396503

RefSeq Status:

VALIDATED

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,368,938 - 129,424,232 (+)	NCBI
mRatBN7.2	3	108,915,263 - 108,970,620 (+)	NCBI

RefSeq Acc Id:

XM_039104968 ⟹ XP_038960896

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,369,086 - 129,421,474 (+)	NCBI
mRatBN7.2	3	108,915,422 - 108,970,620 (+)	NCBI

RefSeq Acc Id:

XM_063283736 ⟹ XP_063139806

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,421,474 (+)	NCBI

RefSeq Acc Id:

XM_063283737 ⟹ XP_063139807

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,411,021 (+)	NCBI

RefSeq Acc Id:

XM_063283738 ⟹ XP_063139808

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,411,021 (+)	NCBI

RefSeq Acc Id:

XR_010064620

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,412,920 (+)	NCBI

RefSeq Acc Id:

XR_010064621

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,412,920 (+)	NCBI

RefSeq Acc Id:

XR_010064622

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,412,920 (+)	NCBI

RefSeq Acc Id:

XR_010064623

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,412,920 (+)	NCBI

RefSeq Acc Id:

XR_010064624

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,412,920 (+)	NCBI

RefSeq Acc Id:

XR_010064625

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,412,920 (+)	NCBI

RefSeq Acc Id:

XR_010064626

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	3	129,365,709 - 129,412,920 (+)	NCBI

Protein Sequences


Protein RefSeqs	NP_001014070	(Get FASTA)	NCBI Sequence Viewer
	NP_001396503	(Get FASTA)	NCBI Sequence Viewer
	XP_038960896	(Get FASTA)	NCBI Sequence Viewer
	XP_063139806	(Get FASTA)	NCBI Sequence Viewer
	XP_063139807	(Get FASTA)	NCBI Sequence Viewer
	XP_063139808	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAH83672	(Get FASTA)	NCBI Sequence Viewer
	EDL80013	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000033786.7
	ENSRNOP00000068736.1
	ENSRNOP00000083281.1
	ENSRNOP00000093407.1
GenBank Protein	Q5XIK8	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001014070 ⟸ NM_001014048

- UniProtKB:

Q5XIK8 (UniProtKB/Swiss-Prot), A6HPR2 (UniProtKB/TrEMBL), A0A8I6AJK5 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MKLRTRKASQQSSPIQTQRTARAKRKYSEVDDSLPSGGEKPSKNETGLLSSIKKFIKGSTPKEE
RENPSKRSRIERDIDNNLITSTPRTGEKPDKQLSRVRRKSPVNGEAGSYEMTNQHIKQNGKLED
NPCSGSPPRTTLLGTIFSPVFNFFSPANKNGTSGSDSPGQAVEAEEIVKQLDMEQVDEITTSTT
SANGAAYSNQAVQVRPSLNNGLEEAEETVTRDIPPLTAPVAPESGYSSAHAEATYEEDWEVFDP
YYFIKHVPPLTEEQLNRKPALPLKTRSTPEFSLVLDLDETLVHCSLNELEDAALTFPVLFQDVI
YQVYVRLRPFFREFLERMSQMYEIILFTASKKVYADKLLNILDPKKQLVRHRLFREHCVCVQGN
YIKDLNILGRDLSKTIIIDNSPQAFAYQLSNGIPIESWFMDKNDNELLKLIPFLEKLVELNEDV
RPHIRDRFRLHDLLPPD

hide sequence

Ensembl Acc Id:

ENSRNOP00000068736 ⟸ ENSRNOT00000078978

Ensembl Acc Id:

ENSRNOP00000033786 ⟸ ENSRNOT00000037168

RefSeq Acc Id:	XP_038960896 ⟸ XM_039104968
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AJK5 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSRNOP00000083281 ⟸ ENSRNOT00000118841

Ensembl Acc Id:

ENSRNOP00000093407 ⟸ ENSRNOT00000106655

RefSeq Acc Id:	NP_001396503 ⟸ NM_001409574
- UniProtKB:	Q5XIK8 (UniProtKB/Swiss-Prot), A6HPR2 (UniProtKB/TrEMBL), A0A8I6AJK5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063139806 ⟸ XM_063283736
- Peptide Label:	isoform X1
- UniProtKB:	A0A8I6AJK5 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_063139807 ⟸ XM_063283737
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_063139808 ⟸ XM_063283738
- Peptide Label:	isoform X3

Protein Domains

FCP1 homology

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q5XIK8-F1-model_v2	AlphaFold	Q5XIK8	1-465	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1309219	AgrOrtholog
BioCyc Gene	G2FUF-48116	BioCyc
Ensembl Genes	ENSRNOG00000022141	Ensembl, UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000037168.7	UniProtKB/TrEMBL
	ENSRNOT00000078978.2	UniProtKB/TrEMBL
	ENSRNOT00000106655.1	UniProtKB/TrEMBL
	ENSRNOT00000118841.1	UniProtKB/TrEMBL
Gene3D-CATH	3.40.50.1000	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7135706	IMAGE-MGC_LOAD
InterPro	Dullard_phosphatase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	FCP1_dom	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HAD-like_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	HAD_sf	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	TIM50	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:311368	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:94517	IMAGE-MGC_LOAD
NCBI Gene	311368	ENTREZGENE
PANTHER	CTD SMALL PHOSPHATASE-LIKE PROTEIN 2	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DULLARD PROTEIN PHOSPHATASE	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	NIF	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Ctdspl2	PhenoGen
PROSITE	FCP1	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
RatGTEx	ENSRNOG00000022141	RatGTEx
SMART	CPDc	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF56784	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A0G2JTJ5_RAT	UniProtKB/TrEMBL
	A0A8I5ZZ06_RAT	UniProtKB/TrEMBL
	A0A8I6AJK5	ENTREZGENE, UniProtKB/TrEMBL
	A6HPR2	ENTREZGENE, UniProtKB/TrEMBL
	CTSL2_RAT	UniProtKB/Swiss-Prot
	F1M9C7_RAT	UniProtKB/TrEMBL
	Q5XIK8	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2015-11-12	Ctdspl2	CTD small phosphatase like 2	Ctdspl2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-02-26	Ctdspl2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2	RGD1309219	similar to hypothetical protein HSPC129	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2005-12-06	RGD1309219	similar to hypothetical protein HSPC129	RGD1309219_predicted	similar to hypothetical protein HSPC129 (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-20	RGD1309219_predicted	similar to hypothetical protein HSPC129 (predicted)	LOC311368_predicted		Symbol and Name status set to approved	1331353	APPROVED
2005-01-12	LOC311368_predicted	similar to hypothetical protein HSPC129 (predicted)			Symbol and Name status set to provisional	70820	PROVISIONAL

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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