Rrp9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein) - Rat Genome Database

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Gene: Rrp9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein) Rattus norvegicus
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Symbol: Rrp9
Name: ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
RGD ID: 1307881
Description: Predicted to enable snoRNA binding activity. Predicted to contribute to U3 snoRNA binding activity. Predicted to be involved in rRNA processing and ribosomal small subunit biogenesis. Predicted to be located in nucleolus. Predicted to be part of box C/D methylation guide snoRNP complex and small-subunit processome. Orthologous to human RRP9 (ribosomal RNA processing 9, U3 small nucleolar RNA binding protein); INTERACTS WITH (+)-schisandrin B; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: LOC363134; ribosomal RNA processing 9, small subunit (SSU) processome component, homolog; ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast); RNA, U3 small nucleolar interacting protein 2; Rnu3ip2; RRP9, small subunit (SSU) processome component, homolog; RRP9, small subunit (SSU) processome component, homolog (yeast); U3 small nucleolar RNA-interacting protein 2
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88115,995,119 - 116,004,832 (+)NCBIGRCr8
mRatBN7.28107,116,411 - 107,126,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,117,471 - 107,126,123 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,740,433 - 112,749,088 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08110,939,609 - 110,948,264 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,782,391 - 108,791,046 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,179,899 - 115,188,551 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,179,893 - 115,188,588 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,544,186 - 114,552,838 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,621,968 - 111,630,963 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18111,641,420 - 111,650,409 (+)NCBI
Celera8106,429,368 - 106,438,021 (+)NCBICelera
Cytogenetic Map8q32NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:9418896   PMID:12477932   PMID:22658674   PMID:22681889   PMID:26867678  


Genomics

Comparative Map Data
Rrp9
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr88115,995,119 - 116,004,832 (+)NCBIGRCr8
mRatBN7.28107,116,411 - 107,126,123 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl8107,117,471 - 107,126,123 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx8112,740,433 - 112,749,088 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.08110,939,609 - 110,948,264 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.08108,782,391 - 108,791,046 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.08115,179,899 - 115,188,551 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl8115,179,893 - 115,188,588 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.08114,544,186 - 114,552,838 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.48111,621,968 - 111,630,963 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.18111,641,420 - 111,650,409 (+)NCBI
Celera8106,429,368 - 106,438,021 (+)NCBICelera
Cytogenetic Map8q32NCBI
RRP9
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38351,933,429 - 51,941,904 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl351,933,429 - 51,941,904 (-)EnsemblGRCh38hg38GRCh38
GRCh37351,967,445 - 51,975,920 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36351,942,486 - 51,950,962 (-)NCBINCBI36Build 36hg18NCBI36
Build 34351,942,485 - 51,950,962NCBI
Celera351,946,271 - 51,954,747 (-)NCBICelera
Cytogenetic Map3p21.2NCBI
HuRef352,030,781 - 52,039,295 (-)NCBIHuRef
CHM1_1351,920,131 - 51,928,646 (-)NCBICHM1_1
T2T-CHM13v2.0351,966,348 - 51,974,823 (-)NCBIT2T-CHM13v2.0
Rrp9
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm399106,354,508 - 106,362,614 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl9106,353,162 - 106,362,623 (+)EnsemblGRCm39 Ensembl
GRCm389106,477,309 - 106,485,415 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl9106,475,963 - 106,485,424 (+)EnsemblGRCm38mm10GRCm38
MGSCv379106,379,640 - 106,387,746 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv369106,335,410 - 106,343,516 (+)NCBIMGSCv36mm8
Celera9106,104,204 - 106,112,359 (+)NCBICelera
Cytogenetic Map9F1NCBI
cM Map957.59NCBI
Rrp9
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555323,581,417 - 3,591,271 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555323,584,111 - 3,591,234 (-)NCBIChiLan1.0ChiLan1.0
RRP9
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2251,927,786 - 51,936,644 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan1351,932,556 - 51,941,415 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v0351,874,829 - 51,883,339 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.1353,103,621 - 53,112,127 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl353,103,621 - 53,112,127 (-)Ensemblpanpan1.1panPan2
RRP9
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12037,774,477 - 37,785,203 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2037,774,516 - 37,784,191 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2037,755,970 - 37,764,232 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02038,125,083 - 38,133,349 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2038,125,042 - 38,134,431 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12037,488,685 - 37,496,949 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02037,897,438 - 37,905,679 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02038,182,533 - 38,190,801 (+)NCBIUU_Cfam_GSD_1.0
Rrp9
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440560266,521,494 - 66,530,586 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365293,282,032 - 3,291,192 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049365293,281,991 - 3,291,049 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
RRP9
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1334,067,520 - 34,075,430 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11334,067,517 - 34,075,425 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21337,264,060 - 37,271,970 (-)NCBISscrofa10.2Sscrofa10.2susScr3
RRP9
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12213,301,525 - 13,310,132 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2213,300,799 - 13,310,137 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_023666041153,625,044 - 153,633,654 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Rrp9
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247305,747,573 - 5,761,456 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247305,752,201 - 5,761,501 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Rrp9
153 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:32
Count of miRNA genes:31
Interacting mature miRNAs:32
Transcripts:ENSRNOT00000017469
Prediction methods:Miranda, Rnahybrid
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303171Bp331Blood pressure QTL 3315.570.005arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)861290298119084929Rat
1549909Stresp11Stress response QTL 116.830.0019stress-related behavior trait (VT:0010451)number of approaches toward negative stimulus before onset of defensive burying response (CMO:0001960)873473045118473045Rat
631210Bw3Body weight QTL35.9mesenteric fat pad mass (VT:0010427)mesenteric fat pad weight to body weight ratio (CMO:0000654)869349194112783834Rat
1358903Bp252Blood pressure QTL 25270.0001arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
1554321Bmd3Bone mineral density QTL 37.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)840952565123900184Rat
9590292Uminl3Urine mineral level QTL 33.620.001urine mineral amount (VT:0015086)urine electrolyte level (CMO:0000593)871888757116888757Rat
8694446Bw170Body weight QTL 17012.070.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)871888757116888757Rat
631650Stl6Serum triglyceride level QTL 640.0019blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)810378157112202585Rat
631653Bp125Blood pressure QTL 1253.3arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)866142385111142385Rat
1581557Eae16Experimental allergic encephalomyelitis QTL 163.8nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis incidence/prevalence measurement (CMO:0001046)88462195110921472Rat
738011Anxrr9Anxiety related response QTL 96.1exploratory behavior trait (VT:0010471)number of entries into a discrete space in an experimental apparatus (CMO:0000960)893535351123900184Rat
724539Cm19Cardiac mass QTL 192.6heart mass (VT:0007028)calculated heart weight (CMO:0000073)8100149864120994388Rat
8693654Alc32Alcohol consumption QTL 3220.755drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)888612425107550209Rat
70197BpQTLcluster8Blood pressure QTL cluster 83.482arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)846531639119088626Rat
738014Anxrr15Anxiety related response QTL 153.60.005locomotor behavior trait (VT:0001392)amount of experiment time spent in a discrete space in an experimental apparatus (CMO:0000958)895718998123900184Rat
2300182Bmd56Bone mineral density QTL 565.4femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)895718998123900184Rat
2300181Bmd55Bone mineral density QTL 555.70.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)876468691121468691Rat
1300171Bp184Blood pressure QTL 1843.66arterial blood pressure trait (VT:2000000)blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)870513503118219066Rat
631217Activ1Activity QTL 115.9voluntary movement trait (VT:0003491)number of photobeam interruptions in an experimental apparatus (CMO:0001517)8102370617108923645Rat
1358893Bp263Blood pressure QTL 2635.01arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)893965141123900184Rat
2313400Anxrr25Anxiety related response QTL 25aggression-related behavior trait (VT:0015014)tameness/aggressiveness composite score (CMO:0002136)889265192114019816Rat
8694200Abfw4Abdominal fat weight QTL 49.070.001visceral adipose mass (VT:0010063)abdominal fat pad weight to body weight ratio (CMO:0000095)871888757116888757Rat
8694392Bw161Body weight QTL 1618.060.001body lean mass (VT:0010483)lean tissue morphological measurement (CMO:0002184)871888757116888757Rat
61437Cia6Collagen induced arthritis QTL 6joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)882460758122812818Rat


Expression

RNA-SEQ Expression

alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
9 11 49 113 91 90 59 25 59 6 218 97 93 45 60 31

Sequence


Ensembl Acc Id: ENSRNOT00000017469   ⟹   ENSRNOP00000017469
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8107,117,471 - 107,126,123 (+)Ensembl
Rnor_6.0 Ensembl8115,179,893 - 115,188,588 (+)Ensembl
Ensembl Acc Id: ENSRNOT00000116446   ⟹   ENSRNOP00000086919
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl8107,117,471 - 107,126,123 (+)Ensembl
RefSeq Acc Id: NM_001108778   ⟹   NP_001102248
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88115,996,180 - 116,004,832 (+)NCBI
mRatBN7.28107,117,471 - 107,126,123 (+)NCBI
Rnor_6.08115,179,899 - 115,188,551 (+)NCBI
Rnor_5.08114,544,186 - 114,552,838 (+)NCBI
RGSC_v3.48111,621,968 - 111,630,963 (+)RGD
Celera8106,429,368 - 106,438,021 (+)RGD
Sequence:
RefSeq Acc Id: XM_039081786   ⟹   XP_038937714
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88115,995,119 - 116,004,825 (+)NCBI
mRatBN7.28107,116,411 - 107,126,116 (+)NCBI
RefSeq Acc Id: XM_063265820   ⟹   XP_063121890
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88116,002,279 - 116,004,825 (+)NCBI
RefSeq Acc Id: XR_005487871
Type: NON-CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr88115,995,119 - 116,003,716 (+)NCBI
mRatBN7.28107,116,411 - 107,126,116 (+)NCBI
RefSeq Acc Id: NP_001102248   ⟸   NM_001108778
- UniProtKB: B0BND5 (UniProtKB/TrEMBL),   F7EPW8 (UniProtKB/TrEMBL),   A0A8I6GFG9 (UniProtKB/TrEMBL)
- Sequence:
Ensembl Acc Id: ENSRNOP00000017469   ⟸   ENSRNOT00000017469
RefSeq Acc Id: XP_038937714   ⟸   XM_039081786
- Peptide Label: isoform X1
- UniProtKB: B0BND5 (UniProtKB/TrEMBL),   F7EPW8 (UniProtKB/TrEMBL),   A0A8I6GFG9 (UniProtKB/TrEMBL)
Ensembl Acc Id: ENSRNOP00000086919   ⟸   ENSRNOT00000116446
RefSeq Acc Id: XP_063121890   ⟸   XM_063265820
- Peptide Label: isoform X2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-B0BND5-F1-model_v2 AlphaFold B0BND5 1-478 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13696254
Promoter ID:EPDNEW_R6779
Type:initiation region
Name:Rrp9_1
Description:ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.08115,179,921 - 115,179,981EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1307881 AgrOrtholog
BioCyc Gene G2FUF-29233 BioCyc
Ensembl Genes ENSRNOG00000012927 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000017469.7 UniProtKB/TrEMBL
  ENSRNOT00000116446.1 UniProtKB/TrEMBL
Gene3D-CATH 2.130.10.10 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7134304 IMAGE-MGC_LOAD
InterPro G-protein_beta_WD-40_rep_reg UniProtKB/TrEMBL
  Rrp9-like UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom UniProtKB/TrEMBL
  WD40_repeat UniProtKB/TrEMBL
  WD40_repeat_dom_sf UniProtKB/TrEMBL
KEGG Report rno:363134 UniProtKB/TrEMBL
MGC_CLONE MGC:188107 IMAGE-MGC_LOAD
NCBI Gene 363134 ENTREZGENE
PANTHER PTHR19865 UniProtKB/TrEMBL
  U3 SMALL NUCLEOLAR RNA-INTERACTING PROTEIN 2 UniProtKB/TrEMBL
Pfam WD40 UniProtKB/TrEMBL
PhenoGen Rrp9 PhenoGen
PRINTS GPROTEINBRPT UniProtKB/TrEMBL
PROSITE WD_REPEATS_2 UniProtKB/TrEMBL
  WD_REPEATS_REGION UniProtKB/TrEMBL
RatGTEx ENSRNOG00000012927 RatGTEx
SMART WD40 UniProtKB/TrEMBL
Superfamily-SCOP WD40_like UniProtKB/TrEMBL
UniProt A0A8I6GFG9 ENTREZGENE, UniProtKB/TrEMBL
  B0BND5 ENTREZGENE, UniProtKB/TrEMBL
  F7EPW8 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2017-06-19 Rrp9  ribosomal RNA processing 9, U3 small nucleolar RNA binding protein  Rrp9  ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-11-20 Rrp9  ribosomal RNA processing 9, small subunit (SSU) processome component, homolog (yeast)  Rrp9  RRP9, small subunit (SSU) processome component, homolog (yeast)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2008-03-07 Rrp9  RRP9, small subunit (SSU) processome component, homolog (yeast)  Rnu3ip2_predicted  RNA, U3 small nucleolar interacting protein 2 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-01-12 Rnu3ip2_predicted  RNA, U3 small nucleolar interacting protein 2 (predicted)      Symbol and Name status set to approved 70820 APPROVED