Atad3a (ATPase family, AAA domain containing 3A)

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Gene: Atad3a (ATPase family, AAA domain containing 3A) Rattus norvegicus

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Symbol:

Atad3a

Name:

ATPase family, AAA domain containing 3A

RGD ID:

1305964

Description:

Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including antiviral innate immune response; mitochondrion organization; and regulation of cell growth. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in Harel-Yoon syndrome and neonatal lethal pontocerebellar hypoplasia, hypotonia, and respiratory insufficiency syndrome. Orthologous to several human genes including ATAD3A (ATPase family AAA domain containing 3A); INTERACTS WITH (+)-schisandrin B; 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol.

Type:

protein-coding

RefSeq Status:

PROVISIONAL

Previously known as:

Atad3; ATPase family AAA domain-containing protein 3; LOC298682; MGC124646

RGD Orthologs

Alliance Orthologs

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	ATAD3A (ATPase family AAA domain containing 3A)	HGNC	EggNOG, Ensembl, HomoloGene, NCBI, OMA, OrthoDB, OrthoMCL, Panther, PhylomeDB, Treefam
Mus musculus (house mouse):	Atad3a (ATPase family, AAA domain containing 3A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	ATAD3A (ATPase family AAA domain containing 3A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	LOC100525876 (ATPase family AAA domain-containing protein 3)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	ATAD3A (ATPase family AAA domain containing 3A)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Other homologs ²
Homo sapiens (human):	ATAD3B (ATPase family AAA domain containing 3B)	HGNC	Inparanoid, Panther, PhylomeDB, Treefam
Homo sapiens (human):	ATAD3C (ATPase family AAA domain containing 3C)	HGNC	EggNOG, Panther, PhylomeDB, Treefam
Alliance orthologs ³
Homo sapiens (human):	ATAD3A (ATPase family AAA domain containing 3A)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Atad3a (ATPase family, AAA domain containing 3A)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ATAD3B (ATPase family AAA domain containing 3B)	Alliance	DIOPT (InParanoid\|OrthoFinder\|PANTHER\|PhylomeDB\|SonicParanoid)
Homo sapiens (human):	ATAD3C (ATPase family AAA domain containing 3C)	Alliance	DIOPT (OrthoFinder\|PANTHER\|PhylomeDB)
Danio rerio (zebrafish):	atad3 (ATPase family AAA domain containing 3)	Alliance	DIOPT (OrthoFinder\|OrthoInspector\|PhylomeDB\|SonicParanoid)
Caenorhabditis elegans (roundworm):	atad-3	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	bor	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Drosophila melanogaster (fruit fly):	bor	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Xenopus tropicalis (tropical clawed frog):	atad3a	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,632,545 - 171,652,725 (-)	NCBI		GRCr8
mRatBN7.2	5	166,350,302 - 166,370,492 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,350,304 - 166,370,482 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	169,055,281 - 169,075,423 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	170,876,707 - 170,896,849 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,839,246 - 170,859,388 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	173,189,590 - 173,209,809 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	173,189,592 - 173,209,768 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	176,665,200 - 176,685,381 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	172,598,553 - 172,618,731 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	172,609,041 - 172,629,268 (-)	NCBI
Celera	5	164,550,758 - 164,570,936 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

cerebellar hypoplasia (ISO)

chromosome 1p36 deletion syndrome (ISO)

congenital myasthenic syndrome 8 (ISO)

dilated cardiomyopathy 1LL (ISO)

Ehlers-Danlos syndrome spondylodysplastic type 2 (ISO)

genetic disease (ISO)

Goldberg-Shprintzen syndrome (ISO)

Harel-Yoon syndrome (ISO)

idiopathic generalized epilepsy (ISO)

immunodeficiency 16 (ISO)

immunodeficiency 38 (ISO)

Joubert syndrome 25 (ISO)

neonatal lethal pontocerebellar hypoplasia, hypotonia, and respiratory insufficiency syndrome (ISO)

Neurodevelopmental Disorders (ISO)

Peroxisome Biogenesis Disorder, Complementation Group 7 (ISO)

Prostatic Neoplasms (ISO)

Shprintzen-Goldberg Craniosynostosis (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

(+)-schisandrin B (EXP)

(1->4)-beta-D-glucan (ISO)

1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane (EXP,ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (EXP,ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (ISO)

2,4-dinitrotoluene (EXP)

2,6-dinitrotoluene (EXP)

3-chloropropane-1,2-diol (EXP)

4,4'-diaminodiphenylmethane (ISO)

4,4'-sulfonyldiphenol (ISO)

4-amino-2,6-dinitrotoluene (EXP)

acrolein (ISO)

aflatoxin B1 (ISO)

alpha-pinene (ISO)

arsenous acid (ISO)

benzo[a]pyrene (ISO)

bisphenol A (EXP,ISO)

bisphenol F (ISO)

caffeine (ISO)

captan (ISO)

carbon nanotube (ISO)

chromium(6+) (ISO)

cisplatin (ISO)

clofibrate (ISO)

clozapine (ISO)

copper atom (ISO)

copper(0) (ISO)

copper(II) chloride (ISO)

crocidolite asbestos (ISO)

diarsenic trioxide (ISO)

Dibutyl phosphate (ISO)

diethylstilbestrol (ISO)

dioxygen (ISO)

enzyme inhibitor (ISO)

epoxiconazole (ISO)

ethanol (ISO)

flutamide (EXP)

folic acid (ISO)

FR900359 (ISO)

genistein (EXP)

glycidyl methacrylate (ISO)

hydrogen peroxide (ISO)

inulin (ISO)

ivermectin (ISO)

ozone (ISO)

paracetamol (ISO)

paraquat (EXP,ISO)

pentachlorophenol (ISO)

perfluorohexanesulfonic acid (ISO)

perfluorononanoic acid (ISO)

perfluorooctane-1-sulfonic acid (ISO)

perfluorooctanoic acid (ISO)

pirinixic acid (ISO)

pregnenolone 16alpha-carbonitrile (ISO)

SB 431542 (ISO)

sodium arsenite (ISO)

tetrachloromethane (EXP)

tetrahydropalmatine (ISO)

thioacetamide (EXP)

tolcapone (EXP)

trichloroethene (EXP)

trimellitic anhydride (ISO)

triptonide (ISO)

tunicamycin (ISO)

urethane (ISO)

valproic acid (ISO)

vinclozolin (EXP)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

antiviral innate immune response (ISO,ISS)

DNA damage response (ISO,ISS)

HRI-mediated signaling (ISO,ISS)

mitochondrion organization (IBA,ISO)

negative regulation of apoptotic process (ISO)

negative regulation of PERK-mediated unfolded protein response (ISO,ISS)

regulation of cell growth (ISO)

Cellular Component

mitochondria-associated endoplasmic reticulum membrane contact site (IEA,ISO)

mitochondrial inner membrane (IEA,ISO)

mitochondrial nucleoid (IEA)

mitochondrion (IBA,ISO)

Molecular Function

ATP binding (IEA,ISO)

ATP hydrolysis activity (IEA,ISO,ISS)

identical protein binding (ISO)

protein binding (ISO)

protein serine/threonine kinase inhibitor activity (ISO,ISS)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
3.	GOA pipeline	RGD automated data pipeline
4.	ClinVar Automated Import and Annotation Pipeline	RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:12477932	PMID:12865426	PMID:14651853	PMID:18614015	PMID:20332122	PMID:23372768	PMID:25375035	PMID:30361391	PMID:30914652

Genomics

Comparative Map Data

Atad3a
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	5	171,632,545 - 171,652,725 (-)	NCBI		GRCr8
mRatBN7.2	5	166,350,302 - 166,370,492 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	5	166,350,304 - 166,370,482 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	5	169,055,281 - 169,075,423 (-)	NCBI	Rnor_SHR	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	5	170,876,707 - 170,896,849 (-)	NCBI	Rnor_SHRSP	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	5	170,839,246 - 170,859,388 (-)	NCBI	Rnor_WKY	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	5	173,189,590 - 173,209,809 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	5	173,189,592 - 173,209,768 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	5	176,665,200 - 176,685,381 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	5	172,598,553 - 172,618,731 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	5	172,609,041 - 172,629,268 (-)	NCBI
Celera	5	164,550,758 - 164,570,936 (-)	NCBI		Celera
Cytogenetic Map	5	q36	NCBI

ATAD3A
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	1	1,512,162 - 1,534,685 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	1	1,512,162 - 1,534,685 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	1	1,447,542 - 1,470,065 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	1	1,437,418 - 1,459,927 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	1	1,532,821 - 1,555,331	NCBI
Celera	1	1,110,376 - 1,132,920 (-)	NCBI		Celera
Cytogenetic Map	1	p36.33	NCBI
HuRef	1	720,811 - 743,664 (+)	NCBI		HuRef
CHM1_1	1	1,434,817 - 1,457,345 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	1	946,666 - 969,189 (+)	NCBI		T2T-CHM13v2.0

Atad3a
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	4	155,825,097 - 155,845,579 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	4	155,825,098 - 155,845,550 (-)	Ensembl		GRCm39 Ensembl
GRCm38	4	155,740,640 - 155,761,124 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	4	155,740,641 - 155,761,093 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	4	155,114,749 - 155,135,207 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	4	154,584,441 - 154,604,893 (-)	NCBI		MGSCv36	mm8
Celera	4	158,012,406 - 158,032,870 (-)	NCBI		Celera
Cytogenetic Map	4	E2	NCBI
cM Map	4	87.2	NCBI

ATAD3A
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	56,587,385 - 56,613,475 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	56,587,428 - 56,612,746 (+)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	56,663,522 - 56,689,500 (+)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	56,789,609 - 56,815,653 (+)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	56,789,621 - 56,815,650 (+)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	56,780,163 - 56,806,214 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	56,672,427 - 56,698,586 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	57,062,790 - 57,088,831 (+)	NCBI		UU_Cfam_GSD_1.0

LOC100525876
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	6	63,701,460 - 63,721,573 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	6	63,706,155 - 63,721,574 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	6	58,310,001 - 58,325,278 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ATAD3A
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	20	129,965,964 - 129,987,866 (-)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
Vero_WHO_p1.0	NW_023666054	34,429,209 - 34,452,701 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Variants

Variants in Atad3a
77 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	89
Count of miRNA genes:	66
Interacting mature miRNAs:	80
Transcripts:	ENSRNOT00000045053
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
10053720	Scort26	Serum corticosterone level QTL 26	2.06	0.0147	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	5	124965598	166875058	Rat
631272	Lanf1	Left ventricular atrial natriuretic factor QTL 1	12		heart left ventricle natriuretic peptide A amount (VT:0010596)	heart left ventricle natriuretic peptide A level (CMO:0002165)	5	151113452	166875058	Rat
1576314	Eutr1	Estrogen induced uterine response QTL 1			uterus integrity trait (VT:0010575)	pyometritis severity score (CMO:0002009)	5	2138965	166875058	Rat
631562	Apr2	Acute phase response QTL 2	3.7		blood murinoglobulin 1 amount (VT:0010597)	plasma murinoglobulin 1 level (CMO:0001931)	5	135927956	166875058	Rat
634349	Bp139	Blood pressure QTL 139		0.001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	128924607	166875058	Rat
61444	Strs2	Sensitivity to stroke QTL 2	4.7		cerebrum integrity trait (VT:0010549)	post-insult time to onset of cerebrovascular lesion (CMO:0002343)	5	135929696	166875058	Rat
724525	Bp147	Blood pressure QTL 147	4.3	0.0001	arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	126424772	166875058	Rat
1549904	Neuinf1	Neuroinflammation QTL 1	3	0	nervous system integrity trait (VT:0010566)	blood T lymphocyte count (CMO:0000110)	5	154828214	166875058	Rat
738018	Anxrr4	Anxiety related response QTL 4	5.1		exploratory behavior trait (VT:0010471)	percentage of entries into a discrete space in an experimental apparatus (CMO:0000961)	5	130130159	166875058	Rat
8552908	Pigfal4	Plasma insulin-like growth factor 1 level QTL 4	6.6		blood insulin-like growth factor amount (VT:0010479)	plasma insulin-like growth factor 1 level (CMO:0001299)	5	128506074	166875058	Rat
7794791	Mcs33	Mammary carcinoma susceptibility QTL 33	1.93		mammary gland integrity trait (VT:0010552)	mammary tumor incidence/prevalence measurement (CMO:0000946)	5	131345754	166875058	Rat
1302790	Scl20	Serum cholesterol level QTL 20	6.4	0.0001	blood cholesterol amount (VT:0000180)	plasma total cholesterol level (CMO:0000585)	5	82394392	166664054	Rat
1598861	Cm64	Cardiac mass QTL 64	2.9		heart mass (VT:0007028)	heart weight to body weight ratio (CMO:0000074)	5	127798274	166875058	Rat
1641920	Colcs1	Colorectal carcinoma susceptibility QTL 1	2.99	0.0055	intestine integrity trait (VT:0010554)	benign colorectal tumor surface area measurement (CMO:0001799)	5	121846814	166846814	Rat
1598819	Bp292	Blood pressure QTL 292	4.3		arterial blood pressure trait (VT:2000000)	systolic blood pressure (CMO:0000004)	5	127798274	166875058	Rat
8694169	Bw148	Body weight QTL 148	5	0.001	body mass (VT:0001259)	body weight gain (CMO:0000420)	5	128506074	166875058	Rat
1331721	Bp210	Blood pressure QTL 210	3.413		arterial blood pressure trait (VT:2000000)	blood pressure time series experimental set point of the baroreceptor response (CMO:0002593)	5	143069996	166846814	Rat

Markers in Region

RH127981

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	5	166,350,464 - 166,350,677 (+)	MAPPER	mRatBN7.2
Rnor_6.0	5	173,189,753 - 173,189,965	NCBI	Rnor6.0
Rnor_5.0	5	176,665,363 - 176,665,575	UniSTS	Rnor5.0
RGSC_v3.4	5	172,598,716 - 172,598,928	UniSTS	RGSC3.4
Celera	5	164,550,921 - 164,551,133	UniSTS
RH 3.4 Map	5	1174.7	UniSTS
Cytogenetic Map	5	q36	UniSTS

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

alimentary part of gastrointestinal system	appendage	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	renal system	reproductive system	respiratory system
9	11	49	113	91	90	59	25	59	6	218	97	93	45	60	31

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001034922	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XR_001837838	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AC105662	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	AC106940	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	BC105762	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473968	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAXUCZ010000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSRNOT00000045053 ⟹ ENSRNOP00000046842

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	166,350,304 - 166,370,482 (-)	Ensembl
Rnor_6.0 Ensembl	5	173,189,592 - 173,209,768 (-)	Ensembl

Ensembl Acc Id:

ENSRNOT00000111763 ⟹ ENSRNOP00000090147

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	5	166,350,304 - 166,370,482 (-)	Ensembl

RefSeq Acc Id:

NM_001034922 ⟹ NP_001030094

RefSeq Status:

PROVISIONAL

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,632,545 - 171,652,725 (-)	NCBI
mRatBN7.2	5	166,350,302 - 166,370,482 (-)	NCBI
Rnor_6.0	5	173,189,590 - 173,209,768 (-)	NCBI
Rnor_5.0	5	176,665,200 - 176,685,381 (-)	NCBI
RGSC_v3.4	5	172,598,553 - 172,618,731 (-)	RGD
Celera	5	164,550,758 - 164,570,936 (-)	RGD

Sequence:

show sequence

GTCACGCTCGAGTACGGTCCACCGAGGGCGCGCGGAGCTTGCAGATCATGTCGTGGCTCTTCGG
CATCAAGGGCCCCAAGGGAGAAGGCACAGGGCCTCCGCTGCCCTTGCCGCCCGCCCAACCTGGG
GCGGAAAGTGGCGGCGACCGTGGTGCGGGAGATCGGCCATCGCCCAAGGACAAATGGAGCAACT
TCGACCCGACGGGCCTGGAGCGTGCGGCCAAAGCGGCGCGCGAGTTGGAGCACTCGCGCCATGC
CAAGGAGGCACTGAATCTTGCACAGATGCAGGAGCAGACACTGCAGCTGGAACAACAGTCTAAG
CTCAAGGAATATGAAGCTGCCGTAGAGCAGCTGAAGAGCGAGCAGATCCGCGTGCAAGCCGAGG
AAAGAAGGAAAACCCTGAACGAAGAGACGCGGCAGCACCAGGCTAGGGCCCAGTACCAGGATAA
GCTAGCCCGACAACGCTATGAGGACCAGCTGAAACAACAGCAACTTCTGAATGAAGAGAATTTA
AGGAAACAAGAGGAATCTGTGCAGAAGCAGGAGGCCATACGGCGAGCCACTGTGGAGCGAGAGA
TGGAGCTGCGGCATAAGAATGAGATGTTGCGGGTGGAAGCTGAGGCTCGAGCACGGGCCAAGGC
CGATCGAGAGAATGCAGACATCATCCGGGAACAGATTCGACTCAAGGCTGCTGAGCACCGCCAG
ACCATCTTGGAGTCTATCAGGACAGCCGGCACCTTGTTTGGTGAAGGATTCCGTGCCTTTGTGA
CAGACTGGGACAAAGTGACAGCCACGGTGGCTGGATTGACACTATTAGCTGTTGGAGTCTATTC
TGCCAAGAACGCTACTTCTGTTGCTGGACGGTATATTGAGGCCCGATTGGGAAAGCCGTCCCTG
GTGAGAGAGACCTCCCGTATCTCAGTGCTGGAGGCATTGAGGCATCCCATCCAGGTCAGCAGGC
GGCTGGTCAGCAGACCCCAGGATGCGTTGGAGGGCGTCATCCTCAGTCCTAGCCTGGAGGCACG
GGTCCGAGATATTGCCATCGCAACAAGAAATACCAAGAAGAACAAAAGCCTGTACAGAAACGTT
CTGATGTATGGGCCACCAGGGACTGGCAAGACACTATTTGCTAAGAAACTCGCACTGCATTCAG
GCATGGACTACGCCATCATGACAGGCGGGGACGTGGCCCCCATGGGGCGGGAGGGTGTGACTGC
CATGCACAAGGTCTTCGACTGGGCAAGCACCAGCAGACGAGGCCTCCTGCTCTTTGTGGATGAA
GCAGATGCCTTCCTCAGGAAGCGAGCAACTGAAAAGATAAGTGAAGACCTCAGGGCTACTCTGA
ATGCATTCCTACACAGGACAGGACAACACAGTAATAAGTTCATGCTGGTCCTGGCCAGTAACCA
GCCTGAGCAGTTCGATTGGGCCATCAATGACCGCATTGACGAGATGGTCTGCTTTGCCCTGCCA
CAGCGGGAGGAGCGGGAGCGCCTGGTGAGAATGTATTTTGACAAGTATGTCCTTAAGCCGGCCA
CAGAAGGAAAGCAACGCTTGAAGGTGGCCCAGTTTGACTACGGAAAGAAGTGCTCAGAGGTCGC
CCAGCTGACGGCGGGAATGTCAGGCCGGGAGATAGCTCAGCTTGCCGTGGCATGGCAGGCCATG
GCATATTCGTCTGAGGATGGGGTCCTCACGGAGGCTATGATGGATGCCCGTGTGCAGGATGCTG
TCCAGCAGCACCAGCAGAAGATGCAGTGGCTTAAAGTAGAGAGACCTGACTCTGAGGCCAGCAA
GCCACCACATCCGTCACTCCTCAGCTGCTGAGCTGGACCTGGACACCTCGTACACCTAACGGGA
CAGCCAGTCTCTATGACCACACTTACTGCTCCTCCCTTTCCTGTCTTCTTTGACCTCTGTAAGA
GGCCATCATTGCCCCAAATGCCTCTGCCGAGCTGTGGGGTGCTGGAGGTGTCAGCTTCTCTGCC
TCCCACACCTCCTAGTCTGTCTCTCTGCGTGCTGGCAGAGGGAAGCATCTGCCTTTCTGTACCT
CAGACTGGCGAGACGCGTCTACAAGCCCAGAGCAGAGAGCACGCAGAGCGCCGTACCACAAGCC
AGTGGCTATGCCAGCAGGACTGGGGCCTTCAGGGACCAGGCTAAAGGAACAGAGGGCCCTCTGC
GTCCTGGACATTACTCCTACCGTACACACATCTGTGCCAAGAATTGGCCCAGTCCTTACTTGGT
AGAGTGGATCTGGTGCTAGACAGCCTTGGCTGGTGGCATCCGAGAATCAGAGCTACCGCCATCC
CCTTGACTGGATCTGGGCCTTTTAAATCCAGAATCTAATAAAACTGTGACTGATAAAAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA

hide sequence

RefSeq Acc Id:

XR_001837838

Type:

NON-CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
GRCr8	5	171,633,214 - 171,652,678 (-)	NCBI
mRatBN7.2	5	166,350,832 - 166,370,492 (-)	NCBI
Rnor_6.0	5	173,190,201 - 173,209,809 (-)	NCBI

Sequence:

show sequence

GTCGCGCCCGCGGCGCGTGGTGATTGCTAGTAGTCCCGAGAGTCACGCTCGAGTACGGTCCACC
GAGGGCGCGCGGAGCTTGCAGATCATGTCGTGGCTCTTCGGCATCAAGGGCCCCAAGGGAGAAG
GCACAGGGCCTCCGCTGCCCTTGCCGCCCGCCCAACCTGGGGCGGAAAGTGGCGGCGACCGTGG
TGCGGGAGATCGGCCATCGCCCAAGGACAAATGGAGCAACTTCGACCCGACGGGCCTGGAGCGT
GCGGCCAAAGCGGCGCGCGAGTTGGAGCACTCGCGCCATGCCAAGGAGGCACTGAATCTTGCAC
AGATGCAGGAGCAGACACTGCAGCTGGAACAACAGTCTAAGCTCAAGGAATATGAAGCTGCCGT
AGAGCAGCTGAAGAGCGAGCAGATCCGCGTGCAAGCCGAGGAAAGAAGGAAAACCCTGAACGAA
GAGACGCGGCAGCACCAGGCTAGGGCCCAGTACCAGGATAAGCTAGCCCGACAACGCTATGAGG
ACCAGCTGAAACAACAGCAACTTCTGAATGAAGAGAATTTAAGGAAACAAGAGGAATCTGTGCA
GAAGCAGGAGGCCATACGGCGAGCCACTGTGGAGCGAGAGATGGAGCTGCGGCATAAGAATGAG
ATGTTGCGGGTGGAAGCTGAGGCTCGAGCACGGGCCAAGGCCGATCGAGAGAATGCAGACATCA
TCCGGGAACAGATTCGACTCAAGGCTGCTGAGCACCGCCAGACCATCTTGGAGTCTATCAGGAC
AGCCGGCACCTTGTTTGGTGAAGGATTCCGTGCCTTTGTGACAGACTGGGACAAAGTGACAGCC
ACGGTGGCTGGATTGACACTATTAGCTGTTGGAGTCTATTCTGCCAAGAACGCTACTTCTGTTG
CTGGACGGTATATTGAGGCCCGATTGGGAAAGCCGTCCCTGGTGAGAGAGACCTCCCGTATCTC
AGTGCTGGAGGCATTGAGGCATCCCATCCAGGTCAGCAGGCGGCTGGTCAGCAGACCCCAGGAT
GCGTTGGAGGGCGTCATCCTCAGTCCTAGCCTGGAGGCACGGGTCCGAGATATTGCCATCGCAA
CAAGAAATACCAAGAAGAACAAAAGCCTGTACAGAAACGTTCTGATGTATGGGCCACCAGGGAC
TGGCAAGACACTATTTGCTAAGAAACTCGCACTGCATTCAGGCATGGACTACGCCATCATGACA
GGCGGGGACGTGGCCCCCATGGGGCGGGAGGGTGTGACTGCCATGCACAAGGTCTTCGACTGGG
CAAGCACCAGCAGACGAGGCCTCCTGCTCTTTGTGGATGAAGCAGATGCCTTCCTCAGGAAGCG
AGCAACTGAAAAGATAAGTGAAGACCTCAGGGCTACTCTGAATGCATTCCTACACAGGACAGGA
CAACACAGTAATAAGTTCATGCTGGTCCTGGCCAGTAACCAGCCTGAGCAGTTCGATTGGGCCA
TCAATGACCGCATTGACGAGATGGTCTGCTTTGCCCTGCCACAGCGGGAGGAGCGGGAGCGCCT
GACGCTTGAAGGTGGCCCAGTTTGACTACGGAAAGAAGTGCTCAGAGGTCGCCCAGCTGACGGC
GGGAATGTCAGGCCGGGAGATAGCTCAGCTTGCCGTGGCATGGCAGGCCATGGCATATTCGTCT
GAGGATGGGGTCCTCACGGAGGCTATGATGGATGCCCGTGTGCAGGATGCTGTCCAGCAGCACC
AGCAGAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001030094	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI05763	(Get FASTA)	NCBI Sequence Viewer
	EDL81320	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSRNOP00000046842.3
	ENSRNOP00000090147.1
	ENSRNOP00055021811
	ENSRNOP00060005618
	ENSRNOP00065012399
GenBank Protein	Q3KRE0	(Get FASTA)	NCBI Sequence Viewer

RefSeq Acc Id:

NP_001030094 ⟸ NM_001034922

- UniProtKB:

Q3KRE0 (UniProtKB/Swiss-Prot), A6IUR9 (UniProtKB/TrEMBL), A0A8I6AD85 (UniProtKB/TrEMBL)

- Sequence:

show sequence

MSWLFGIKGPKGEGTGPPLPLPPAQPGAESGGDRGAGDRPSPKDKWSNFDPTGLERAAKAAREL
EHSRHAKEALNLAQMQEQTLQLEQQSKLKEYEAAVEQLKSEQIRVQAEERRKTLNEETRQHQAR
AQYQDKLARQRYEDQLKQQQLLNEENLRKQEESVQKQEAIRRATVEREMELRHKNEMLRVEAEA
RARAKADRENADIIREQIRLKAAEHRQTILESIRTAGTLFGEGFRAFVTDWDKVTATVAGLTLL
AVGVYSAKNATSVAGRYIEARLGKPSLVRETSRISVLEALRHPIQVSRRLVSRPQDALEGVILS
PSLEARVRDIAIATRNTKKNKSLYRNVLMYGPPGTGKTLFAKKLALHSGMDYAIMTGGDVAPMG
REGVTAMHKVFDWASTSRRGLLLFVDEADAFLRKRATEKISEDLRATLNAFLHRTGQHSNKFML
VLASNQPEQFDWAINDRIDEMVCFALPQREERERLVRMYFDKYVLKPATEGKQRLKVAQFDYGK
KCSEVAQLTAGMSGREIAQLAVAWQAMAYSSEDGVLTEAMMDARVQDAVQQHQQKMQWLKVERP
DSEASKPPHPSLLSC

hide sequence

Ensembl Acc Id:

ENSRNOP00000046842 ⟸ ENSRNOT00000045053

Ensembl Acc Id:

ENSRNOP00000090147 ⟸ ENSRNOT00000111763

Protein Domains

AAA+ ATPase

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-Q3KRE0-F1-model_v2	AlphaFold	Q3KRE0	1-591	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13694328

Promoter ID:

EPDNEW_R4853

Type:

initiation region

Name:

Atad3a_1

Description:

ATPase family, AAA domain containing 3A

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	5	173,209,781 - 173,209,841	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1305964	AgrOrtholog
BioCyc Gene	G2FUF-38903	BioCyc
Ensembl Genes	ENSRNOG00000018118	Ensembl, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ENSRNOG00055015867	UniProtKB/Swiss-Prot
	ENSRNOG00060004416	UniProtKB/Swiss-Prot
	ENSRNOG00065010139	UniProtKB/Swiss-Prot
Ensembl Transcript	ENSRNOT00000045053.4	UniProtKB/Swiss-Prot
	ENSRNOT00000111763.1	UniProtKB/TrEMBL
	ENSRNOT00055027006	UniProtKB/Swiss-Prot
	ENSRNOT00060007415	UniProtKB/Swiss-Prot
	ENSRNOT00065016341	UniProtKB/Swiss-Prot
Gene3D-CATH	3.40.50.300	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:7929859	IMAGE-MGC_LOAD
InterPro	AAA+_ATPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ATAD3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	ATAD3_N	UniProtKB/TrEMBL
	ATPase_AAA_core	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DUF3523	UniProtKB/Swiss-Prot
	P-loop_NTPase	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report	rno:298682	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGC_CLONE	MGC:124646	IMAGE-MGC_LOAD
NCBI Gene	298682	ENTREZGENE
PANTHER	ATPASE FAMILY AAA DOMAIN-CONTAINING PROTEIN 3	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	PTHR23075	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam	AAA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
	DUF3523	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen	Atad3a	PhenoGen
RatGTEx	ENSRNOG00000018118	RatGTEx
	ENSRNOG00055015867	RatGTEx
	ENSRNOG00060004416	RatGTEx
	ENSRNOG00065010139	RatGTEx
SMART	AAA	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP	SSF52540	UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt	A0A8I6AD85	ENTREZGENE, UniProtKB/TrEMBL
	A6IUR9	ENTREZGENE, UniProtKB/TrEMBL
	ATAD3_RAT	UniProtKB/Swiss-Prot, ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2005-12-06	Atad3a	ATPase family, AAA domain containing 3A	Atad3a_predicted	ATPase family, AAA domain containing 3A (predicted)	Symbol and Name updated	1559027	APPROVED
2005-01-12	Atad3a_predicted	ATPase family, AAA domain containing 3A (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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