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Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Object Symbol | Species | Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | Tspan9 | Rat | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | [APC protein affects the susceptibility to 1 and 2-Dimethylhydrazine] which results in decreased expression of TSPAN9 mRNA | CTD | PMID:27840820 | Tspan9 | Rat | 1,3,5-trinitro-1,3,5-triazinane | decreases expression | EXP | | 6480464 | cyclonite results in decreased expression of TSPAN9 mRNA | CTD | PMID:25559034 | Tspan9 | Rat | 17beta-estradiol | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Estradiol results in decreased expression of TSPAN9 mRNA | CTD | PMID:31614463 more ... | Tspan9 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of TSPAN9 mRNA | CTD | PMID:22298810 and PMID:34747641 | Tspan9 | Rat | 2,3,7,8-tetrachlorodibenzodioxine | decreases expression | ISO | Tspan9 (Mus musculus) | 6480464 | Tetrachlorodibenzodioxin results in decreased expression of TSPAN9 mRNA | CTD | PMID:26290441 | Tspan9 | Rat | 2,4,6-tribromophenol | increases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | 2 more ... | CTD | PMID:31675489 | Tspan9 | Rat | 2-bromohexadecanoic acid | multiple interactions | ISO | TSPAN9 (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TSPAN9 protein] | CTD | PMID:38195004 | Tspan9 | Rat | 4,4'-sulfonyldiphenol | decreases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | bisphenol S results in decreased methylation of TSPAN9 gene | CTD | PMID:31601247 | Tspan9 | Rat | 4-hydroxyphenyl retinamide | increases expression | ISO | Tspan9 (Mus musculus) | 6480464 | Fenretinide results in increased expression of TSPAN9 mRNA | CTD | PMID:28973697 | Tspan9 | Rat | 6-propyl-2-thiouracil | decreases expression | EXP | | 6480464 | Propylthiouracil results in decreased expression of TSPAN9 mRNA | CTD | PMID:24780913 | Tspan9 | Rat | 6-propyl-2-thiouracil | increases expression | EXP | | 6480464 | Propylthiouracil results in increased expression of TSPAN9 mRNA | CTD | PMID:30047161 | Tspan9 | Rat | aflatoxin B1 | decreases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | Aflatoxin B1 results in decreased methylation of TSPAN9 3' UTR and Aflatoxin B1 results in decreased methylation of TSPAN9 intron | CTD | PMID:30157460 | Tspan9 | Rat | Aflatoxin B2 alpha | increases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | aflatoxin B2 results in increased methylation of TSPAN9 intron | CTD | PMID:30157460 | Tspan9 | Rat | amitrole | increases expression | EXP | | 6480464 | Amitrole results in increased expression of TSPAN9 mRNA | CTD | PMID:30047161 | Tspan9 | Rat | antirheumatic drug | increases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Antirheumatic Agents results in increased expression of TSPAN9 mRNA | CTD | PMID:24449571 | Tspan9 | Rat | aristolochic acid A | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | aristolochic acid I results in decreased expression of TSPAN9 protein | CTD | PMID:33212167 | Tspan9 | Rat | benzo[a]pyrene | decreases expression | ISO | Tspan9 (Mus musculus) | 6480464 | Benzo(a)pyrene results in decreased expression of TSPAN9 mRNA | CTD | PMID:19770486 | Tspan9 | Rat | benzo[a]pyrene | affects methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of TSPAN9 3' UTR and Benzo(a)pyrene affects the methylation of TSPAN9 5' UTR | CTD | PMID:27901495 and PMID:30157460 | Tspan9 | Rat | benzo[a]pyrene | increases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of TSPAN9 3' UTR | CTD | PMID:27901495 | Tspan9 | Rat | benzo[a]pyrene | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in decreased expression of TSPAN9 mRNA | CTD | PMID:22316170 and PMID:32234424 | Tspan9 | Rat | benzo[e]pyrene | affects methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | benzo(e)pyrene affects the methylation of TSPAN9 3' UTR | CTD | PMID:30157460 | Tspan9 | Rat | benzo[e]pyrene | increases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | benzo(e)pyrene results in increased methylation of TSPAN9 intron | CTD | PMID:30157460 | Tspan9 | Rat | beta-naphthoflavone | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | beta-Naphthoflavone results in decreased expression of TSPAN9 mRNA | CTD | PMID:32858204 | Tspan9 | Rat | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of TSPAN9 mRNA | CTD | PMID:25181051 more ... | Tspan9 | Rat | bisphenol A | increases expression | ISO | Tspan9 (Mus musculus) | 6480464 | bisphenol A results in increased expression of TSPAN9 mRNA | CTD | PMID:32156529 | Tspan9 | Rat | bisphenol A | decreases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | bisphenol A results in decreased methylation of TSPAN9 gene | CTD | PMID:31601247 | Tspan9 | Rat | bisphenol A | increases expression | EXP | | 6480464 | bisphenol A results in increased expression of TSPAN9 mRNA | CTD | PMID:34947998 | Tspan9 | Rat | bisphenol A | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | bisphenol A analog results in decreased expression of TSPAN9 mRNA | CTD | PMID:32387340 | Tspan9 | Rat | bisphenol A | increases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | bisphenol A results in increased expression of TSPAN9 mRNA | CTD | PMID:32387340 | Tspan9 | Rat | cadmium atom | multiple interactions | ISO | TSPAN9 (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TSPAN9 protein] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TSPAN9 protein | CTD | PMID:38195004 | Tspan9 | Rat | cadmium dichloride | multiple interactions | ISO | TSPAN9 (Homo sapiens) | 6480464 | 2-bromopalmitate inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TSPAN9 protein] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased palmitoylation of TSPAN9 protein | CTD | PMID:38195004 | Tspan9 | Rat | carbon nanotube | increases expression | ISO | Tspan9 (Mus musculus) | 6480464 | Nanotubes and Carbon results in increased expression of TSPAN9 mRNA | CTD | PMID:25554681 | Tspan9 | Rat | CGP 52608 | multiple interactions | ISO | TSPAN9 (Homo sapiens) | 6480464 | CGP 52608 promotes the reaction [RORA protein binds to TSPAN9 gene] | CTD | PMID:28238834 | Tspan9 | Rat | cisplatin | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Cisplatin results in decreased expression of TSPAN9 mRNA | CTD | PMID:19561079 | Tspan9 | Rat | clofibrate | multiple interactions | ISO | Tspan9 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of TSPAN9 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TSPAN9 mRNA] | CTD | PMID:17585979 | Tspan9 | Rat | clofibrate | decreases expression | ISO | Tspan9 (Mus musculus) | 6480464 | Clofibrate results in decreased expression of TSPAN9 mRNA | CTD | PMID:17585979 and PMID:23811191 | Tspan9 | Rat | cyclosporin A | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Cyclosporine results in decreased expression of TSPAN9 mRNA | CTD | PMID:25562108 | Tspan9 | Rat | Dibutyl phosphate | affects expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | di-n-butylphosphoric acid affects the expression of TSPAN9 mRNA | CTD | PMID:37042841 | Tspan9 | Rat | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of TSPAN9 mRNA | CTD | PMID:21266533 | Tspan9 | Rat | epoxiconazole | decreases expression | ISO | Tspan9 (Mus musculus) | 6480464 | epoxiconazole results in decreased expression of TSPAN9 mRNA | CTD | PMID:35436446 | Tspan9 | Rat | ethanol | increases expression | ISO | Tspan9 (Mus musculus) | 6480464 | Ethanol results in increased expression of TSPAN9 mRNA | CTD | PMID:30319688 | Tspan9 | Rat | ethanol | affects expression | ISO | Tspan9 (Mus musculus) | 6480464 | Ethanol affects the expression of TSPAN9 mRNA | CTD | PMID:30319688 | Tspan9 | Rat | ethanol | affects splicing | ISO | Tspan9 (Mus musculus) | 6480464 | Ethanol affects the splicing of TSPAN9 mRNA | CTD | PMID:30319688 | Tspan9 | Rat | gallic acid | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Gallic Acid results in decreased expression of TSPAN9 mRNA | CTD | PMID:34408198 | Tspan9 | Rat | isobutanol | multiple interactions | ISO | TSPAN9 (Homo sapiens) | 6480464 | [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in decreased expression of TSPAN9 mRNA | CTD | PMID:29432896 | Tspan9 | Rat | lipopolysaccharide | multiple interactions | ISO | TSPAN9 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of TSPAN9 mRNA | CTD | PMID:35811015 | Tspan9 | Rat | methapyrilene | increases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | Methapyrilene results in increased methylation of TSPAN9 intron | CTD | PMID:30157460 | Tspan9 | Rat | methapyrilene | affects methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | Methapyrilene affects the methylation of TSPAN9 3' UTR | CTD | PMID:30157460 | Tspan9 | Rat | methimazole | increases expression | EXP | | 6480464 | Methimazole results in increased expression of TSPAN9 mRNA | CTD | PMID:30047161 | Tspan9 | Rat | methoxychlor | affects methylation | EXP | | 6480464 | Methoxychlor affects the methylation of TSPAN9 gene | CTD | PMID:35440735 | Tspan9 | Rat | paracetamol | affects expression | ISO | Tspan9 (Mus musculus) | 6480464 | Acetaminophen affects the expression of TSPAN9 mRNA | CTD | PMID:17562736 | Tspan9 | Rat | paracetamol | multiple interactions | ISO | Tspan9 (Mus musculus) | 6480464 | [Clofibrate co-treated with Acetaminophen] affects the expression of TSPAN9 mRNA and PPARA affects the reaction [[Clofibrate co-treated with Acetaminophen] affects the expression of TSPAN9 mRNA] | CTD | PMID:17585979 | Tspan9 | Rat | perfluorohexanesulfonic acid | decreases expression | ISO | Tspan9 (Mus musculus) | 6480464 | perfluorohexanesulfonic acid results in decreased expression of TSPAN9 mRNA | CTD | PMID:37995155 | Tspan9 | Rat | perfluorooctanoic acid | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | perfluorooctanoic acid results in decreased expression of TSPAN9 protein | CTD | PMID:26879310 | Tspan9 | Rat | phenobarbital | increases expression | EXP | | 6480464 | Phenobarbital results in increased expression of TSPAN9 mRNA | CTD | PMID:30047161 | Tspan9 | Rat | pirinixic acid | multiple interactions | ISO | TSPAN9 (Homo sapiens) | 6480464 | [pirinixic acid binds to and results in increased activity of PPARA protein] which results in decreased expression of TSPAN9 mRNA | CTD | PMID:19710929 | Tspan9 | Rat | pirinixic acid | decreases expression | ISO | Tspan9 (Mus musculus) | 6480464 | pirinixic acid results in decreased expression of TSPAN9 mRNA | CTD | PMID:23811191 | Tspan9 | Rat | potassium chromate | increases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | potassium chromate(VI) results in increased expression of TSPAN9 mRNA | CTD | PMID:22714537 | Tspan9 | Rat | S-(1,2-dichlorovinyl)-L-cysteine | multiple interactions | ISO | TSPAN9 (Homo sapiens) | 6480464 | [S-(1 and 2-dichlorovinyl)cysteine co-treated with Lipopolysaccharides] results in decreased expression of TSPAN9 mRNA | CTD | PMID:35811015 | Tspan9 | Rat | silicon dioxide | decreases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Silicon Dioxide analog results in decreased expression of TSPAN9 mRNA | CTD | PMID:25895662 | Tspan9 | Rat | silicon dioxide | decreases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | Silicon Dioxide results in decreased methylation of TSPAN9 gene | CTD | PMID:34973136 | Tspan9 | Rat | sodium arsenite | increases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | sodium arsenite results in increased expression of TSPAN9 mRNA | CTD | PMID:38568856 | Tspan9 | Rat | sulfadimethoxine | increases expression | EXP | | 6480464 | Sulfadimethoxine results in increased expression of TSPAN9 mRNA | CTD | PMID:30047161 | Tspan9 | Rat | sunitinib | increases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Sunitinib results in increased expression of TSPAN9 mRNA | CTD | PMID:31533062 | Tspan9 | Rat | tert-butyl hydroperoxide | increases expression | ISO | Tspan9 (Mus musculus) | 6480464 | tert-Butylhydroperoxide results in increased expression of TSPAN9 mRNA | CTD | PMID:15003993 | Tspan9 | Rat | titanium dioxide | affects expression | ISO | Tspan9 (Mus musculus) | 6480464 | titanium dioxide affects the expression of TSPAN9 mRNA | CTD | PMID:17656681 | Tspan9 | Rat | triadimefon | increases expression | EXP | | 6480464 | triadimefon results in increased expression of TSPAN9 mRNA | CTD | PMID:30047161 | Tspan9 | Rat | triphenyl phosphate | affects expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | triphenyl phosphate affects the expression of TSPAN9 mRNA | CTD | PMID:37042841 | Tspan9 | Rat | valproic acid | increases expression | ISO | TSPAN9 (Homo sapiens) | 6480464 | Valproic Acid results in increased expression of TSPAN9 mRNA | CTD | PMID:23179753 | Tspan9 | Rat | valproic acid | increases methylation | ISO | TSPAN9 (Homo sapiens) | 6480464 | Valproic Acid results in increased methylation of TSPAN9 gene | CTD | PMID:29154799 | |