Advanced Search (OLGA)

Gene: ALOX15B (arachidonate 15-lipoxygenase type B) Canis lupus familiaris

Analyze

Symbol:

ALOX15B

Name:

arachidonate 15-lipoxygenase type B

RGD ID:

12416451

Description:

ENCODES a protein that exhibits arachidonate 12(S)-lipoxygenase activity (inferred); arachidonate 15-lipoxygenase activity (inferred); arachidonate 8(S)-lipoxygenase activity (inferred); INVOLVED IN arachidonate metabolic process (inferred); cannabinoid biosynthetic process (inferred); endocannabinoid signaling pathway (inferred); PARTICIPATES IN acetylsalicylic acid pharmacodynamics pathway; antipyrine drug pathway; arachidonic acid metabolic pathway; ASSOCIATED WITH autism spectrum disorder (ortholog); COVID-19 (ortholog); FOUND IN nucleus (ortholog)

Type:

protein-coding

RefSeq Status:

MODEL

Previously known as:

arachidonate 15-lipoxygenase B; arachidonate 15-lipoxygenase, type B; polyunsaturated fatty acid lipoxygenase ALOX15B

RGD Orthologs

Alliance Orthologs

More Info

more info ...

Latest Assembly:

CanFam3.1 - Dog CanFam3.1 Assembly

Position:

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	32,878,348 - 32,888,253 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	32,878,338 - 32,888,316 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	33,014,628 - 33,024,494 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	32,981,218 - 32,991,101 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	32,981,035 - 32,991,180 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	32,948,241 - 32,958,102 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	32,904,002 - 32,913,858 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	33,084,046 - 33,093,901 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

JBrowse:

View Region in Genome Browser (JBrowse)

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

autism spectrum disorder (ISO)

COVID-19 (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

arachidonate metabolic process (IBA,IEA)

cannabinoid biosynthetic process (IEA)

endocannabinoid signaling pathway (IEA)

hepoxilin biosynthetic process (IBA)

linoleic acid metabolic process (IBA,IEA)

lipid metabolic process (IEA)

lipid oxidation (IBA,IEA)

lipoxin A4 biosynthetic process (IEA)

lipoxygenase pathway (IBA,IEA)

negative regulation of cell cycle (IEA)

negative regulation of cell population proliferation (IEA)

negative regulation of growth (IEA)

phospholipid metabolic process (IEA)

positive regulation of chemokine production (IEA)

positive regulation of keratinocyte differentiation (IEA)

positive regulation of macrophage derived foam cell differentiation (IEA)

positive regulation of peroxisome proliferator activated receptor signaling pathway (IEA)

Cellular Component

adherens junction (IEA)

cytoplasm (IEA)

cytoskeleton (IEA)

cytosol (IEA)

focal adhesion (IEA)

lipid droplet (IEA)

membrane (IEA)

nucleus (ISO)

plasma membrane (IEA)

Molecular Function

arachidonate 12(S)-lipoxygenase activity (IEA)

arachidonate 15-lipoxygenase activity (IBA,IEA)

arachidonate 8(S)-lipoxygenase activity (IEA)

calcium ion binding (IEA)

dioxygenase activity (IEA)

iron ion binding (IEA)

linoleate 13S-lipoxygenase activity (IEA)

linoleate 9S-lipoxygenase activity (IEA)

metal ion binding (IEA)

oxidoreductase activity (IEA)

oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen (IEA)

protein binding (ISO)

Molecular Pathway Annotations Click to see Annotation Detail View

acetylsalicylic acid pharmacodynamics pathway (ISO)

antipyrine drug pathway (ISO)

arachidonic acid metabolic pathway (ISO)

celecoxib pharmacodynamics pathway (ISO)

diclofenac pharmacodynamics pathway (ISO)

diflunisal pharmacodynamics pathway (ISO)

etodolac pharmacodynamics pathway (ISO)

fenoprofen pharmacodynamics pathway (ISO)

flurbiprofen pharmacodynamics pathway (ISO)

ibuprofen pharmacodynamics pathway (ISO)

indometacin pharmacodynamics pathway (ISO)

ketoprofen pharmacodynamics pathway (ISO)

ketorolac pharmacodynamics pathway (ISO)

leukotriene C4 synthase deficiency pathway (ISO)

lipoxygenase mediated pathway of arachidonic acid metabolism (ISO)

lornoxicam pharmacodynamics pathway (ISO)

magnesium salicylate pharmacodynamics pathway (ISO)

mefenamic acid pharmacodynamics pathway (ISO)

meloxicam pharmacodynamics pathway (ISO)

nabumetone pharmacodynamics pathway (ISO)

naproxen pharmacodynamics pathway (ISO)

paracetamol drug pathway (ISO)

piroxicam pharmacodynamics pathway (ISO)

salicylic acid pharmacodynamics pathway (ISO)

sodium salicylate pharmacodynamics pathway (ISO)

sulindac pharmacodynamics pathway (ISO)

tenoxicam pharmacodynamics pathway (ISO)

tiaprofenic acid pharmacodynamics pathway (ISO)

tolmetin pharmacodynamics pathway (ISO)

valdecoxib pharmacodynamics pathway (ISO)

References

Additional References at PubMed

PMID:22301074	PMID:30032202

Genomics

Comparative Map Data

ALOX15B
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	5	32,878,348 - 32,888,253 (+)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	5	32,878,338 - 32,888,316 (+)	Ensembl			canFam3	CanFam3.1
Dog10K_Boxer_Tasha	5	33,014,628 - 33,024,494 (+)	NCBI	Dog10K_Boxer_Tasha	Dog10K_Boxer_Tasha
ROS_Cfam_1.0	5	32,981,218 - 32,991,101 (+)	NCBI	ROS_Cfam_1.0	ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	5	32,981,035 - 32,991,180 (+)	Ensembl				ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	5	32,948,241 - 32,958,102 (+)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	5	32,904,002 - 32,913,858 (+)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	5	33,084,046 - 33,093,901 (+)	NCBI	UU_Cfam_GSD_1.0	UU_Cfam_GSD_1.0

ALOX15B
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	17	8,039,059 - 8,049,134 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p14 Ensembl	17	8,039,011 - 8,049,134 (+)	Ensembl			hg38	GRCh38
GRCh37	17	7,942,377 - 7,952,452 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	17	7,883,083 - 7,893,177 (+)	NCBI	Build 36	Build 36	hg18	NCBI36
Build 34	17	7,883,126 - 7,893,174	NCBI
Celera	17	7,969,928 - 7,980,051 (+)	NCBI		Celera
Cytogenetic Map	17	p13.1	NCBI
HuRef	17	7,837,153 - 7,847,282 (+)	NCBI		HuRef
CHM1_1	17	7,951,127 - 7,961,240 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	17	7,944,477 - 7,954,568 (+)	NCBI		T2T-CHM13v2.0

Alox8
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	11	69,074,711 - 69,088,669 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	11	69,074,758 - 69,088,669 (-)	Ensembl		GRCm39 Ensembl		GRCm39
GRCm38	11	69,183,885 - 69,197,843 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	11	69,183,932 - 69,197,843 (-)	Ensembl			mm10	GRCm38
MGSCv37	11	68,997,387 - 69,011,341 (-)	NCBI	MGSCv37	MGSCv37	mm9	NCBIm37
MGSCv36	11	69,000,080 - 69,014,034 (-)	NCBI		MGSCv36	mm8
Celera	11	76,136,086 - 76,151,253 (-)	NCBI		Celera
Cytogenetic Map	11	B3	NCBI
cM Map	11	42.38	NCBI

Alox15b
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCr8	10	54,391,331 - 54,400,648 (-)	NCBI	GRCr8	GRCr8		GRCr8
GRCr8 Ensembl	10	54,391,302 - 54,400,648 (-)	Ensembl				GRCr8
mRatBN7.2	10	53,892,496 - 53,901,812 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	10	53,892,466 - 53,901,812 (-)	Ensembl				mRatBN7.2
UTH_Rnor_SHR_Utx	10	58,554,201 - 58,563,570 (-)	NCBI	UTH_Rnor_SHR_Utx	UTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0	10	58,042,809 - 58,052,178 (-)	NCBI	UTH_Rnor_SHRSP_BbbUtx_1.0	UTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0	10	53,550,911 - 53,560,210 (-)	NCBI	UTH_Rnor_WKY_Bbb_1.0	UTH_Rnor_WKY_Bbb_1.0
Rnor_6.0	10	55,773,748 - 55,783,489 (-)	NCBI	Rnor_6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	10	55,774,006 - 55,783,489 (-)	Ensembl			rn6	Rnor6.0
Rnor_5.0	10	55,517,096 - 55,526,545 (-)	NCBI	Rnor_5.0	Rnor_5.0	rn5
RGSC_v3.4	10	55,951,005 - 55,960,265 (-)	NCBI	RGSC_v3.4	RGSC_v3.4	rn4
Celera	10	53,057,844 - 53,067,039 (-)	NCBI		Celera
RGSC_v3.1	10	55,964,626 - 55,973,888 (-)	NCBI
Cytogenetic Map	10	q24	NCBI

Alox15b
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955467	8,895,095 - 8,906,009 (-)	Ensembl
ChiLan1.0	NW_004955467	8,896,740 - 8,906,032 (-)	NCBI	ChiLan1.0	ChiLan1.0

LOC100971127
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
NHGRI_mPanPan1-v2	19	65,704,347 - 65,715,938 (-)	NCBI		NHGRI_mPanPan1-v2
NHGRI_mPanPan1	17	70,509,809 - 70,525,379 (-)	NCBI		NHGRI_mPanPan1
Mhudiblu_PPA_v0	17	43,609,146 - 43,619,713 (-)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3
PanPan1.1	17	48,340,759 - 48,350,808 (-)	NCBI	PanPan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	17	48,340,777 - 48,350,808 (-)	Ensembl			panPan2	panpan1.1

Alox15b
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024405602	47,805,676 - 47,815,516 (+)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936595	1,279,944 - 1,288,321 (+)	Ensembl		SpeTri2.0 Ensembl
SpeTri2.0	NW_004936595	1,279,944 - 1,288,321 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

ALOX15B
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	12	53,271,583 - 53,281,123 (+)	Ensembl			susScr11	Sscrofa11.1
Sscrofa11.1	12	53,259,867 - 53,281,127 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	12	55,734,620 - 55,757,204 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

ALOX15B
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	16	7,425,533 - 7,435,896 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	16	7,425,990 - 7,435,327 (+)	Ensembl		ChlSab1.1 Ensembl	chlSab2	Vervet-AGM
Vero_WHO_p1.0	NW_023666059	13,969,096 - 13,979,121 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Alox15b
(Rattus rattus - black rat)

Black Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Black Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Rrattus_CSIRO_v1	9	48,783,817 - 48,792,778 (-)	NCBI		Rrattus_CSIRO_v1

Variants

Variants in ALOX15B
91 total Variants

Expression

RNA-SEQ Expression

Click on a value in the shaded box below the category label to view a detailed expression data table for that system.

Download All Expressed Objects for this Gene

adipose tissue	alimentary part of gastrointestinal system	circulatory system	ectoderm	endocrine system	endoderm	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	mesenchyme	mesoderm	nervous system	reproductive system	respiratory system
6	5	5	23	22	16	6	6	6	6	32	21	12	14	10

Sequence

Nucleotide Sequences


RefSeq Transcripts	XM_038477636	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038477637	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038504551	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038535522	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038535523	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038599744	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038599745	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664273	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_038664274	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_546603	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	AAEX04000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAHUQ010000062	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAQRD010000089	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JAAUVH010000371	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	REHQ01000005	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Ensembl Acc Id:

ENSCAFT00000026794 ⟹ ENSCAFP00000024897

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,878,338 - 32,888,316 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000060879 ⟹ ENSCAFP00000058672

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,878,338 - 32,888,316 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000060921 ⟹ ENSCAFP00000050439

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,878,338 - 32,888,316 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000069635 ⟹ ENSCAFP00000053193

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,878,338 - 32,888,316 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000077688 ⟹ ENSCAFP00000063831

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,878,338 - 32,888,316 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00000081556 ⟹ ENSCAFP00000065495

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1 Ensembl	5	32,878,338 - 32,888,316 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845048173 ⟹ ENSCAFP00845037788

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	32,981,035 - 32,991,180 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845048267 ⟹ ENSCAFP00845037862

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	32,981,035 - 32,991,180 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845048361 ⟹ ENSCAFP00845037942

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	32,981,035 - 32,991,180 (+)	Ensembl

Ensembl Acc Id:

ENSCAFT00845048413 ⟹ ENSCAFP00845037981

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0 Ensembl	5	32,981,035 - 32,991,180 (+)	Ensembl

RefSeq Acc Id:

XM_038477636 ⟹ XP_038333564

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	32,948,241 - 32,958,102 (+)	NCBI

RefSeq Acc Id:

XM_038477637 ⟹ XP_038333565

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UMICH_Zoey_3.1	5	32,948,241 - 32,958,102 (+)	NCBI

RefSeq Acc Id:

XM_038504551 ⟹ XP_038360479

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
Dog10K_Boxer_Tasha	5	33,014,628 - 33,024,494 (+)	NCBI

RefSeq Acc Id:

XM_038535522 ⟹ XP_038391450

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	33,084,046 - 33,093,901 (+)	NCBI

RefSeq Acc Id:

XM_038535523 ⟹ XP_038391451

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UU_Cfam_GSD_1.0	5	33,084,046 - 33,093,901 (+)	NCBI

RefSeq Acc Id:

XM_038599744 ⟹ XP_038455672

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	32,904,002 - 32,913,858 (+)	NCBI

RefSeq Acc Id:

XM_038599745 ⟹ XP_038455673

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
UNSW_CanFamBas_1.0	5	32,904,002 - 32,913,858 (+)	NCBI

RefSeq Acc Id:

XM_038664273 ⟹ XP_038520201

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	32,981,218 - 32,991,101 (+)	NCBI

RefSeq Acc Id:

XM_038664274 ⟹ XP_038520202

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
ROS_Cfam_1.0	5	32,981,218 - 32,991,101 (+)	NCBI

RefSeq Acc Id:

XM_546603 ⟹ XP_546603

Type:

CODING

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	32,878,348 - 32,888,253 (+)	NCBI
Dog10K_Boxer_Tasha	5	33,014,628 - 33,024,494 (+)	NCBI

Sequence:

show sequence

CAGGGCGTGTCCCCGGCTGAGCCGCCAGCTTTAAAGCTGTCAGCAGCCGCAGGAGACAGCCAGA
CTTGGGCTGGAACTATGGCCGAGTTCAGCGTGACAGTGTCCACTGGGGAGGCCATCGGGGCCGG
CACGTGGAACAAAATAGCCGTCAGCCTCGTGGGGACCCGGGGAGAGACGCCCCCCCTGCGCCTG
GACCATCCGGGCAAGGAGTTCAGCGCGGGCGCTGTGGAGGACTTCCAGGTGGCGTCCCCCCAGG
ACGTGGGCCCGCTGCTGCTGCTGCGCGTGCACAAGGCGCCCCTGCTGCTGCCCGCCCCGGTCGG
GCCGGTGGCCCGTGACGCCTGGTTCTGCCGCTGGTTCCAGCTCACGCCGCCCCAGGGCGCCCCC
TTGCGCTTCCCCTGCTACCAGTGGCTGGAGGGCGCGGGAAGCCTGGCGCTGCGCGCAGGGGCCG
CCAAAGTCCCCTGGGCGGACGACCACCCCATCCTGCAGCAACAGCGCCAGGACGAGCTGAAGGC
CAGGCAGGACTCGTACCACTGGAAGACATACAGCCCGGGCTGGCCTCACTGCCTGGATGAGAAG
TCTGTGAAAGATCTGGATCTCAACATCAAATACTCTGTAATGAAGAATTCCTGCTTCTACCTGA
AAGTCAGCTCCGCGATTACGGAGCTGAAACTCAAGGGGCTGCTGGACCGCAAGGGGCCCTGGAA
GAGTCTGAATGAGATGAAAAGGATGTTCAACTTCCGGAAGACCCCAGCCGCTGAGTACACGTTG
GAACACTGGCAGGAGGACACCTTCTTCGCCTCCCAGTTCCTGAATGGCCTCAACCCTGTCCTGA
TCCGCCGCTGTGGCCACCTCCCAGAGAACTTCCCCGTCACTGATGACATGGTGGCCCCGGTGCT
GGGCCCCGGGACCAGTCTGCAGGCCGAGCTGGAGAGGGGCTCCCTGTTCCTGGTGGATCACGGC
ATCCTCTGCGGCGTCCGCACCAATCTCATTAACGGGAAGCCTCAGTTCTCCGCAGCCCCGATGA
CCCTGCTGTACCAGAGCCCCGGGGGAGGGCCGCTGCTGCCCCTTGCCATCCAGCTCAGCCAAAC
TCCAGGACCCGCCAGCCCCATCTTCCTGCCCAGTGACAACAAGTGGGACTGGCTGCTGGCCAAG
ACATGGGTGCGCAATGCCGAATTCTCGGTCCATGAGGCTGTCACGCACCTGTTGCATGCGCACC
TGCTGCCAGAGGTTTTCACCATGGCTACACTGCGCCAGCTGCCCCACTGCCACCCACTCTTCAA
GCTGTTGATCCCACACACTCGGTATACCTTGCACATCAACACTCTGGCCCGTGAGCTGCTCATC
GCCCCAGGGCAGGTGGTGGACAGGTCCACAGGCATTGGCATTGGAGGCTTCTCTGAGCTGATAC
AGAGGAACATGGAGCAGCTAAACTATTCTGTCTTGTGTCTGCCTGAAGATATCCAGGCCCGTGG
AGTCAAAGACATCCCAAACTACTACTACCGGGATGATGGGCTGAAGATCTGGGGTGCAGTGGAG
AGCTTTGTCTCCGAGATAATCAACATCTACTACCCGAGTGATGCATCCGTGTGTGAGGACGGTG
AACTCCAGGCCTGGGTGTGGGAGATCTTCTCCGAGGGCTTCCTGGGCAGGGAGAGCTCAGGTAT
GCCCTTCTCACTGGAGACCCGGGAAGCCCTGGTGCAGTATGTCACCATGGTGATATTCAACTGC
TCAGCCAAGCACTATGCCGTCAGTGCGGGGCAGTTTGACTCCTGTGTCTGGATGCCCAACCTGC
CCGCCAGCATGCAGCTGCCACCCCCCACCTCTAAAGGCCAGACAAGGCCAGAAAGGTTTCTAGC
TACCCTCCCGCCGGTCAATGCCACATGTGACATTATTGTGGCCCTCTGGTTGCTGAGCAAGGAG
CCTGGAGACCAACGGCCCCTGGGCACCTACCCAGAGGAGCACTTCACAGAGGAGGCTCCCCAGC
AGAGCATCGCGACCTTCCAGAGCCGCCTGACCCAGATCTCAAAGGAGATCCGGGAGCGGAACCA
GGAGCTGGCACTGCCCTACACCTACCTGGACCCTCCGCTCATTGAAAACAGTGTGTCCATCTAA
CTCCCCTGAAGAACGAGGTGCTCTGAGGCCTCCCTTTGACCCATCAATCCAGGCCACCCAGACC
AAAGGACTCCCCCAGAAAACCTGTGCCCCATATGCCTCACCTGGGACAACCAAGCCACCTGTAA
CTCACCCCACACACACAACACAACAACAGAAACAAAACAGAGAAACAAAAGGCCCCAGAGAACA
GGACTTTCATGAGACAGTACCTTTTGAAGAACCCAAGCTTCCAAGTGCCTGAACACCCACAGTT
CCCTTAAAGGGTTTTATAACTTTGTTTTGCTTTGCATTTATGCCTTACATTACGATGAGAGGGG
GATGTAATCCTACCCCTGATCCCACTGACCGCAGCTGAGTGGACCTAATGGCCACCTCACCTCC
TACAGGCTTCCCAGCAGCACAAGGGGTGGCAGGTGGAAAAATCGCCCAAGAGGTTGATAGTGAC
CTATGGTCCCAGCTAGAAAATGAACAACCCACAAAGAAGGGGCCACCAGAAGCAGGGCAGGAGA
AGGACGACTTTCTGGGACACGCAGGCTGTGCCCACATATGCTTTCTTAAAAACTTGCTCCAAAG
TTGGACAAAAGGCACCTGGGTGGCTCAGTCAGTTGGGCATCTGCCTTCAGCTCAGATCATGATC
CTGGGGTCCTGCGATTGAGCCCCCAAGTCGGGCTCCCTTCTGAGCGGGGAATCTGTTTCTGCCT
CTGCCCCTCCTCCTGCC

hide sequence

Protein Sequences


Protein RefSeqs	XP_038333564	(Get FASTA)	NCBI Sequence Viewer
	XP_038333565	(Get FASTA)	NCBI Sequence Viewer
	XP_038360479	(Get FASTA)	NCBI Sequence Viewer
	XP_038391450	(Get FASTA)	NCBI Sequence Viewer
	XP_038391451	(Get FASTA)	NCBI Sequence Viewer
	XP_038455672	(Get FASTA)	NCBI Sequence Viewer
	XP_038455673	(Get FASTA)	NCBI Sequence Viewer
	XP_038520201	(Get FASTA)	NCBI Sequence Viewer
	XP_038520202	(Get FASTA)	NCBI Sequence Viewer
	XP_546603	(Get FASTA)	NCBI Sequence Viewer
Ensembl Protein	ENSCAFP00000053193.2
	ENSCAFP00000058672.2
	ENSCAFP00000063831.2
	ENSCAFP00030024961.1
	ENSCAFP00040012707.1
	ENSCAFP00040012757.1
	ENSCAFP00040012792.1
	ENSCAFP00040012863.1
	ENSCAFP00040012903.1
	ENSCAFP00845037788.1
	ENSCAFP00845037862
	ENSCAFP00845037862.1
	ENSCAFP00845037942.1
	ENSCAFP00845037981.1

RefSeq Acc Id:	XP_546603 ⟸ XM_546603
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0QDK5 (UniProtKB/TrEMBL), A0A8I3Q2D9 (UniProtKB/TrEMBL), A0A8C0K384 (UniProtKB/TrEMBL), A0A8C0NH48 (UniProtKB/TrEMBL)
- Sequence:	show sequence MAEFSVTVSTGEAIGAGTWNKIAVSLVGTRGETPPLRLDHPGKEFSAGAVEDFQVASPQDVGPL LLLRVHKAPLLLPAPVGPVARDAWFCRWFQLTPPQGAPLRFPCYQWLEGAGSLALRAGAAKVPW ADDHPILQQQRQDELKARQDSYHWKTYSPGWPHCLDEKSVKDLDLNIKYSVMKNSCFYLKVSSA ITELKLKGLLDRKGPWKSLNEMKRMFNFRKTPAAEYTLEHWQEDTFFASQFLNGLNPVLIRRCG HLPENFPVTDDMVAPVLGPGTSLQAELERGSLFLVDHGILCGVRTNLINGKPQFSAAPMTLLYQ SPGGGPLLPLAIQLSQTPGPASPIFLPSDNKWDWLLAKTWVRNAEFSVHEAVTHLLHAHLLPEV FTMATLRQLPHCHPLFKLLIPHTRYTLHINTLARELLIAPGQVVDRSTGIGIGGFSELIQRNME QLNYSVLCLPEDIQARGVKDIPNYYYRDDGLKIWGAVESFVSEIINIYYPSDASVCEDGELQAW VWEIFSEGFLGRESSGMPFSLETREALVQYVTMVIFNCSAKHYAVSAGQFDSCVWMPNLPASMQ LPPPTSKGQTRPERFLATLPPVNATCDIIVALWLLSKEPGDQRPLGTYPEEHFTEEAPQQSIAT FQSRLTQISKEIRERNQELALPYTYLDPPLIENSVSI hide sequence

Ensembl Acc Id:

ENSCAFP00000058672 ⟸ ENSCAFT00000060879

Ensembl Acc Id:

ENSCAFP00000053193 ⟸ ENSCAFT00000069635

Ensembl Acc Id:

ENSCAFP00000050439 ⟸ ENSCAFT00000060921

Ensembl Acc Id:

ENSCAFP00000063831 ⟸ ENSCAFT00000077688

Ensembl Acc Id:

ENSCAFP00000024897 ⟸ ENSCAFT00000026794

Ensembl Acc Id:

ENSCAFP00000065495 ⟸ ENSCAFT00000081556

RefSeq Acc Id:	XP_038333565 ⟸ XM_038477637
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038333564 ⟸ XM_038477636
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038455673 ⟸ XM_038599745
- Peptide Label:	isoform X2

RefSeq Acc Id:	XP_038455672 ⟸ XM_038599744
- Peptide Label:	isoform X1

RefSeq Acc Id:	XP_038520202 ⟸ XM_038664274
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K384 (UniProtKB/TrEMBL), A0A8C0NH48 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038520201 ⟸ XM_038664273
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0QDK5 (UniProtKB/TrEMBL), A0A8I3Q2D9 (UniProtKB/TrEMBL), A0A8C0K384 (UniProtKB/TrEMBL), A0A8C0NH48 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038360479 ⟸ XM_038504551
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K384 (UniProtKB/TrEMBL), A0A8C0NH48 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038391451 ⟸ XM_038535523
- Peptide Label:	isoform X2
- UniProtKB:	A0A8C0K384 (UniProtKB/TrEMBL), A0A8C0NH48 (UniProtKB/TrEMBL)

RefSeq Acc Id:	XP_038391450 ⟸ XM_038535522
- Peptide Label:	isoform X1
- UniProtKB:	A0A8C0K384 (UniProtKB/TrEMBL), A0A8C0NH48 (UniProtKB/TrEMBL), A0A8C0QDK5 (UniProtKB/TrEMBL), A0A8I3Q2D9 (UniProtKB/TrEMBL)

Ensembl Acc Id:

ENSCAFP00845037788 ⟸ ENSCAFT00845048173

Ensembl Acc Id:

ENSCAFP00845037862 ⟸ ENSCAFT00845048267

Ensembl Acc Id:

ENSCAFP00845037981 ⟸ ENSCAFT00845048413

Ensembl Acc Id:

ENSCAFP00845037942 ⟸ ENSCAFT00845048361

Protein Domains

Lipoxygenase PLAT

Promoters

RGD ID:

13683238

Promoter ID:

EPDNEW_C1307

Type:

single initiation site

Name:

ALOX15B_1

Description:

arachidonate 15-lipoxygenase, type B

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Dog Assembly	Chr	Position (strand)	Source
CanFam3.1	5	32,878,409 - 32,878,469	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
Ensembl Genes	ENSCAFG00000016928	Ensembl, UniProtKB/TrEMBL
	ENSCAFG00030015346	UniProtKB/TrEMBL
	ENSCAFG00040007882	UniProtKB/TrEMBL
	ENSCAFG00845027303	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript	ENSCAFT00000060879.2	UniProtKB/TrEMBL
	ENSCAFT00000069635.2	UniProtKB/TrEMBL
	ENSCAFT00000077688.2	UniProtKB/TrEMBL
	ENSCAFT00030028622.1	UniProtKB/TrEMBL
	ENSCAFT00040014688.1	UniProtKB/TrEMBL
	ENSCAFT00040014747.1	UniProtKB/TrEMBL
	ENSCAFT00040014784.1	UniProtKB/TrEMBL
	ENSCAFT00040014860.1	UniProtKB/TrEMBL
	ENSCAFT00040014906.1	UniProtKB/TrEMBL
	ENSCAFT00845048173.1	UniProtKB/TrEMBL
	ENSCAFT00845048267	ENTREZGENE
	ENSCAFT00845048267.1	UniProtKB/TrEMBL
	ENSCAFT00845048361.1	UniProtKB/TrEMBL
	ENSCAFT00845048413.1	UniProtKB/TrEMBL
Gene3D-CATH	3.10.450.60	UniProtKB/TrEMBL
	Lipoxygenase-1, Domain 5	UniProtKB/TrEMBL
	PLAT/LH2 domain	UniProtKB/TrEMBL
InterPro	LipOase	UniProtKB/TrEMBL
	LipOase_C	UniProtKB/TrEMBL
	LipOase_C_sf	UniProtKB/TrEMBL
	LipOase_CS	UniProtKB/TrEMBL
	LipOase_Fe_BS	UniProtKB/TrEMBL
	LipOase_mml	UniProtKB/TrEMBL
	PLAT/LH2_dom	UniProtKB/TrEMBL
	PLAT/LH2_dom_sf	UniProtKB/TrEMBL
	PLAT_LOX_verte	UniProtKB/TrEMBL
NCBI Gene	ALOX15B	ENTREZGENE
PANTHER	PTHR11771	UniProtKB/TrEMBL
Pfam	Lipoxygenase	UniProtKB/TrEMBL
	PLAT	UniProtKB/TrEMBL
PRINTS	LIPOXYGENASE	UniProtKB/TrEMBL
	MAMLPOXGNASE	UniProtKB/TrEMBL
PROSITE	LIPOXYGENASE_1	UniProtKB/TrEMBL
	LIPOXYGENASE_2	UniProtKB/TrEMBL
	LIPOXYGENASE_3	UniProtKB/TrEMBL
	PLAT	UniProtKB/TrEMBL
SMART	LH2	UniProtKB/TrEMBL
Superfamily-SCOP	SSF48484	UniProtKB/TrEMBL
	SSF49723	UniProtKB/TrEMBL
UniProt	A0A8C0K384	ENTREZGENE
	A0A8C0NH48	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0QDK5	ENTREZGENE, UniProtKB/TrEMBL
	A0A8C0QDX6_CANLF	UniProtKB/TrEMBL
	A0A8C0QE39_CANLF	UniProtKB/TrEMBL
	A0A8C0QG99_CANLF	UniProtKB/TrEMBL
	A0A8C0QIZ6_CANLF	UniProtKB/TrEMBL
	A0A8I3PS89_CANLF	UniProtKB/TrEMBL
	A0A8I3PU89_CANLF	UniProtKB/TrEMBL
	A0A8I3Q0Z3_CANLF	UniProtKB/TrEMBL
	A0A8I3Q2D9	ENTREZGENE, UniProtKB/TrEMBL
VGNC ID	VGNC:37812	ENTREZGENE

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2019-01-29	ALOX15B	arachidonate 15-lipoxygenase type B		arachidonate 15-lipoxygenase, type B	Symbol and/or name change	5135510	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB

Send us a Message

Imported Disease Annotations - CTD

RGD Manual Annotations

Imported Annotations - SMPDB