Pdcd1 Gene Search Result

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6 records found for search term Pdcd1

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RGD ID	Symbol	Name	Description	Chr	Start	Stop	Species	Annotations	Match	Type
1323232	Pdcd1	programmed cell death 1	Predicted to enable signaling receptor activity. Involved in negative regulation of immune response. Acts upstream of or within negative regulation of B cell apoptotic process; negative regulation of tolerance induction; and positive regulation of T cell apoptotic process. Located in external side o ... (more) f plasma membrane. Is expressed in retina. Used to study dilated cardiomyopathy and systemic lupus erythematosus. Human ortholog(s) of this gene implicated in autoimmune disease (multiple); hepatitis B; hepatitis C; hepatocellular carcinoma; and lupus nephritis. Orthologous to human PDCD1 (programmed cell death 1). [provided by Alliance of Genome Resources, Apr 2025]	1	93966027	93980278	Mouse	270	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1553554	Cd274	CD274 antigen	The protein encoded by this gene is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobulin V-like and C-like domai ... (more) ns. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Mice deficient for this gene display a variety of phenotypes including decreased allogeneic fetal survival rates and severe experimental autoimmune encephalomyelitis. [provided by RefSeq, Sep 2015]	19	29339428	29365495	Mouse	404	old_gene_name , old_gene_symbol	gene, protein-coding, REVIEWED [RefSeq]
1552436	Pdcd1lg2	programmed cell death 1 ligand 2	Acts upstream of or within negative regulation of T cell proliferation and positive regulation of T cell proliferation. Predicted to be located in plasma membrane. Predicted to be active in external side of plasma membrane. Is expressed in several structures, including alimentary system epithelium; ... (more) forebrain; nose; retina; and skin. Orthologous to human PDCD1LG2 (programmed cell death 1 ligand 2). [provided by Alliance of Genome Resources, Jul 2025]	19	29388319	29450327	Mouse	110	symbol , old_gene_name , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1550654	Pdcd10	programmed cell death 10	Predicted to enable protein homodimerization activity and protein kinase binding activity. Acts upstream of or within cellular response to leukemia inhibitory factor. Predicted to be located in Golgi membrane; cell periphery; and cytosol. Predicted to be part of FAR/SIN/STRIPAK complex. Is expressed ... (more) in several structures, including cardiovascular system; central nervous system; gonad; gut; and retina layer. Used to study cerebral cavernous malformation 3. Human ortholog(s) of this gene implicated in cerebral cavernous malformation 3. Orthologous to human PDCD10 (programmed cell death 10). [provided by Alliance of Genome Resources, Jul 2025]	3	75423797	75464159	Mouse	237	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1312660	Pdcd11	programmed cell death 11	Predicted to enable NF-kappaB binding activity and RNA binding activity. Predicted to be involved in rRNA processing. Located in cytosol. Is expressed in several structures, including blastocyst; brain; early embryo; olfactory epithelium; and thymus primordium. Orthologous to human PDCD1 ... (more) -weight:700;'>PDCD11 (programmed cell death 11). [provided by Alliance of Genome Resources, Jul 2025]	19	47079183	47119585	Mouse	99	symbol , PhenoGen , description	gene, protein-coding, VALIDATED [RefSeq]
1617462	Pgcka1	PDCD10 and GCKIII kinases associated 1	Is expressed in brain; gut; respiratory system; submandibular gland primordium; and urinary system. Orthologous to human PGCKA1 (PDCD10 and GCKIII kinases associated 1). [provided by Alliance of Genome Resources, Apr 2025]	5	63969833	64056968	Mouse	64	old_gene_name , name , description	gene, protein-coding, VALIDATED [RefSeq]