| 1318589 | Hsd3b1 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 | Enables steroid Delta-isomerase activity. Involved in androgen biosynthetic process. Located in mitochondrion. Is expressed in several structures, including endocrine gland; genitourinary system; liver; nervous system; and respiratory system. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 98749672 | 98767110 | Mouse | 597 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1615188 | Hsd3b2 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 | Predicted to enable 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity and steroid Delta-isomerase activity. Predicted to be involved in C21-steroid hormone biosynthetic process; androgen biosynthetic process; and negative regulation of iron ion transport. Predicted to be located in several cellular components, including intercellular bridge; mitochondrial envelope; and nucleolus. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in liver. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 98618423 | 98631859 | Mouse | 48 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1615187 | Hsd3b3 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 | Predicted to enable 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity and steroid Delta-isomerase activity. Predicted to be involved in C21-steroid hormone biosynthetic process; androgen biosynthetic process; and negative regulation of iron ion transport. Located in mitochondrial inner mem brane. Is expressed in adrenal gland; embryo; liver; testis; and testis medullary region. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 98648792 | 98672465 | Mouse | 93 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1615186 | Hsd3b4 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 | Predicted to enable 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity; steroid Delta-isomerase activity; and steroid binding activity. Involved in response to stilbenoid. Located in mitochondrial inner membrane. Is expressed in several structures, including alimentary system; eye; genitour inary system; heart; and nervous system. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 98406387 | 98417895 | Mouse | 63 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1553473 | Hsd3b5 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 | Predicted to enable 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity; steroid Delta-isomerase activity; and steroid binding activity. Involved in response to stilbenoid. Located in mitochondrial inner membrane. Is expressed in several structures, including adrenal gland; genitourinary sys tem; gut; liver and biliary system; and spleen. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Jul 2025] | 3 | 98525952 | 98552850 | Mouse | 101 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 1615185 | Hsd3b6 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 | Predicted to enable 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity and steroid Delta-isomerase activity. Predicted to be involved in C21-steroid hormone biosynthetic process; androgen biosynthetic process; and negative regulation of iron ion transport. Predicted to be located in several cellular components, including intercellular bridge; mitochondrial envelope; and nucleolus. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; brain; cardiovascular system; extraembryonic component; and genitourinary system. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 98712820 | 98721759 | Mouse | 71 | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2307760 | Hsd3b8 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 8 | Predicted to enable 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity; steroid Delta-isomerase activity; and steroid binding activity. Predicted to be involved in progesterone metabolic process; regulation of steroid biosynthetic process; and steroid biosynthetic process. Predicted to be l ocated in several cellular components, including intercellular bridge; mitochondrial envelope; and nucleolus. Is expressed in several structures, including alimentary system; eye; heart; integumental system; and nervous system. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 98459858 | 98471366 | Mouse | | description | gene, protein-coding, VALIDATED [RefSeq] |
| 2307758 | Hsd3b9 | hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 9 | Predicted to enable 3-beta-hydroxy-Delta5-steroid dehydrogenase (NAD+) activity; steroid Delta-isomerase activity; and steroid binding activity. Predicted to be involved in progesterone metabolic process; regulation of steroid biosynthetic process; and steroid biosynthetic process. Predicted to be l ocated in several cellular components, including intercellular bridge; mitochondrial envelope; and nucleolus. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including alimentary system; eye; heart; integumental system; and nervous system. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2). [provided by Alliance of Genome Resources, Apr 2025] | 3 | 98352991 | 98364833 | Mouse | 22 | description | gene, protein-coding, VALIDATED [RefSeq] |