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Gene: Hsd3b6 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6) Mus musculus
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Symbol: Hsd3b6
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6
Description: Predicted to have 3-beta-hydroxy-delta5-steroid dehydrogenase activity. Predicted to be involved in several processes, including C21-steroid hormone metabolic process; hippocampus development; and response to corticosterone. Predicted to localize to several cellular components, including the intercellular bridge; mitochondrial envelope; and nucleolus. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Is expressed in several structures, including adrenal gland; alimentary system; brain; cardiovascular system; and genitourinary system. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2); PARTICIPATES IN steroid hormone biosynthetic pathway; INTERACTS WITH 1H-pyrazole; 4,4'-diaminodiphenylmethane; 4,4'-sulfonyldiphenol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 6; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type VI; 3-beta-HSD VI; 3beta-HSD VI; D19210; hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 pseudogene; hydroxysteroid dehydrogenase-6, delta<5>-3-beta
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl398,805,504 - 98,814,443 (-)Ensembl
GRCm38398,805,504 - 98,814,443 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37398,609,427 - 98,618,366 (-)NCBIGRCm37mm9NCBIm37
MGSCv36398,934,566 - 98,943,498 (-)NCBImm8
Celera3100,140,076 - 100,149,017 (-)NCBICelera
Cytogenetic Map3 F2.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hsd3b6
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615185
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-12-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.