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Gene: Hsd3b4 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4) Mus musculus
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Symbol: Hsd3b4
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4
Description: Predicted to have 3-beta-hydroxy-delta5-steroid dehydrogenase activity and steroid binding activity. Involved in response to stilbenoid. Localizes to the mitochondrial inner membrane. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Is expressed in several structures, including alimentary system; eye; heart; nervous system; and urinary system. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2); PARTICIPATES IN steroid hormone biosynthetic pathway; INTERACTS WITH (+)-dexrazoxane; (R)-lipoic acid; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3 beta-hydroxysteroid dehydrogenase 4; 3 beta-hydroxysteroid dehydrogenase type 4; 3 beta-hydroxysteroid dehydrogenase type IV; 3-beta-HSD IV; 3-beta-hydroxy-5-ene steroid dehydrogenase; 3-beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase; dihydrotestosterone 3-ketoreductase; hydroxysteroid dehydrogenase-4, delta<5>-3-beta; NADPH-dependent 3-beta-hydroxy-Delta(5)-steroid dehydrogenase; NADPH-dependent 3-keto-steroid reductase Hsd3b4; progesterone reductase
Orthologs:
No known orthologs. homologs ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl398,499,071 - 98,510,514 (-)Ensembl
GRCm38398,499,071 - 98,510,579 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37398,303,003 - 98,314,490 (-)NCBIGRCm37mm9NCBIm37
MGSCv36398,584,487 - 98,595,899 (-)NCBImm8
Cytogenetic Map3 F2.2NCBI
cM Map342.79NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


References - curated
References - uncurated

Genomics

Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hsd3b4
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615186
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.