| 1552726 | Dhh | desert hedgehog | Enables patched binding activity. Involved in several processes, including Schwann cell development; male gonad development; and paracrine signaling. Acts upstream of or within several processes, including Leydig cell differentiation; male sex determination; and osteoblast differentiation. Predicted to be located in plasma membrane. Predicted to be active in extracellular space. Is expressed in several structures, including brain; genitourinary system; gut; heart and pericardium; and yolk sac. Used to study 46,XY complete gonadal dysgenesis. Human ortholog(s) of this gene implicated in 46,XY complete gonadal dysgenesis; 46,XY gonadal dysgenesis with minifascicular neuropathy; and 46,XY sex reversal 7. Orthologous to human DHH (desert hedgehog signaling molecule). [provided by Alliance of Genome Resources, Jul 2025] | 15 | 98779496 | 98796443 | Mouse | 164 | symbol , PhenoGen , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1313262 | Zdhhc1 | zinc finger, DHHC domain containing 1 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of protein-containing complex assembly. Acts upstream of or within protein palmitoylation. Located in end osome membrane. Is expressed in several structures, including adrenal gland; central nervous system; genitourinary system; heart; and lung. Orthologous to human ZDHHC1 (zinc finger DHHC-type containing 1). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 106199055 | 106223694 | Mouse | 84 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 736614 | Zdhhc2 | zinc finger, DHHC domain containing 2 | Enables protein-cysteine S-myristoyltransferase activity; protein-cysteine S-palmitoyltransferase activity; and protein-cysteine S-stearoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation; protein localization to membrane; and synapse assembly. Acts upstream of or within postsy naptic neurotransmitter receptor cycle and protein palmitoylation. Located in plasma membrane; postsynaptic recycling endosome; and recycling endosome membrane. Is expressed in several structures, including early conceptus; genitourinary system; nervous system; pancreas tip epithelium; and retina. Orthologous to human ZDHHC2 (zinc finger DHHC-type palmitoyltransferase 2). [provided by Alliance of Genome Resources, Apr 2025] | 8 | 40876526 | 40946178 | Mouse | 208 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1319161 | Zdhhc3 | zinc finger, DHHC domain containing 3 | Enables protein homodimerization activity and protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; positive regulation of GABAergic synaptic transmission; and positive regulation of receptor localization to synapse. Acts ups tream of or within protein targeting. Located in Golgi apparatus. Is expressed in central nervous system; early conceptus; genitourinary system; and ileum. Orthologous to human ZDHHC3 (zinc finger DHHC-type palmitoyltransferase 3). [provided by Alliance of Genome Resources, Jul 2025] | 9 | 122895224 | 122942269 | Mouse | 128 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1318129 | Zdhhc4 | zinc finger, DHHC domain containing 4 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in positive regulation of innate immune response; protein localization to plasma membrane; and protein targeting to membrane. Predicted to be located in Golgi membrane; endoplasmic reticulum membrane; and plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in early conceptus; inner cell mass; oocyte; and pancreas tip epithelium. Orthologous to human ZDHHC4 (zinc finger DHHC-type palmitoyltransferase 4). [provided by Alliance of Genome Resources, Apr 2025] | 5 | 143302244 | 143315007 | Mouse | 72 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1314628 | Zdhhc5 | zinc finger, DHHC domain containing 5 | Enables palmitoyltransferase activity. Involved in positive regulation of defense response and positive regulation of protein localization. Acts upstream of or within non-canonical inflammasome complex assembly; protein maturation; and protein palmitoylation. Located in dendrite; phagocytic vesicle; and plasma membrane. Is active in glutamatergic synapse and postsynapse. Is expressed in early conceptus; eye; heart; oocyte; and trunk somite. Orthologous to human ZDHHC5 (zinc finger DHHC-type palmitoyltransferase 5). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 84518264 | 84545508 | Mouse | 148 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1551983 | Zdhhc6 | zinc finger, DHHC domain containing 6 | Predicted to enable protein-cysteine S-palmitoyltransferase activity and protein-cysteine S-stearoyltransferase activity. Involved in protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed i n several structures, including eye; genitourinary system; heart; lung epithelium; and trunk somite. Orthologous to human ZDHHC6 (zinc finger DHHC-type palmitoyltransferase 6). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 55286648 | 55304468 | Mouse | 69 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1332314 | Zdhhc7 | zinc finger, DHHC domain containing 7 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in glucose import in response to insulin stimulus; peptidyl-L-cysteine S-palmitoylation; and regulation of protein localization to plasma membrane. Located in Golgi apparatus. Is expressed in central nervous system; early conceptus; and genitourinary system. Orthologous to human ZDHHC7 (zinc finger DHHC-type palmitoyltransferase 7). [provided by Alliance of Genome Resources, Jul 2025] | 8 | 120807834 | 120828211 | Mouse | 152 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1557928 | Zdhhc8 | zinc finger, DHHC domain containing 8 | Predicted to enable palmitoyltransferase activity. Involved in regulation of postsynapse assembly. Acts upstream of or within locomotory behavior. Located in mitochondrion. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including brain; cardiovascular system; forelimb bud; ganglia; and nose. Orthologous to human ZDHHC8 (zinc finger DHHC-type palmitoyltransferase 8). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 18038612 | 18056471 | Mouse | 80 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1556934 | Zdhhc9 | zinc finger, DHHC domain containing 9 | Predicted to enable Ras palmitoyltransferase activity. Involved in positive regulation of pyroptotic inflammatory response. Acts upstream of or within non-canonical inflammasome complex assembly and protein maturation. Predicted to be located in Golgi membrane and cytosol. Predicted to be part of pa lmitoyltransferase complex. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in cerebral cortex ventricular layer and cortical plate. Used to study syndromic X-linked intellectual disability Raymond type. Human ortholog(s) of this gene implicated in syndromic X-linked intellectual disability Raymond type. Orthologous to human ZDHHC9 (zinc finger DHHC-type palmitoyltransferase 9). [provided by Alliance of Genome Resources, Apr 2025] | X | 47260844 | 47297792 | Mouse | 136 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1616743 | Zdhhc11 | zinc finger, DHHC domain containing 11 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in antiviral innate immune response; peptidyl-L-cysteine S-palmitoylation; and positive regulation of defense response to virus by host. Located in endosome membrane. Is expressed in brain; male reproductive gland or organ; metanephr os; and submandibular gland. Orthologous to human ZDHHC11 (zinc finger DHHC-type containing 11) and ZDHHC11B (zinc finger DHHC-type containing 11B). [provided by Alliance of Genome Resources, Jul 2025] | 13 | 74111970 | 74141109 | Mouse | 30 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1315299 | Zdhhc12 | zinc finger, DHHC domain containing 12 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in gephyrin clustering involved in postsynaptic density assembly; peptidyl-L-cysteine S-palmitoylation; and positive regulation of GABAergic synaptic transmission. Located in Golgi apparatus. Is expressed in early conceptus; inner ce ll mass; and oocyte. Orthologous to human ZDHHC12 (zinc finger DHHC-type palmitoyltransferase 12). [provided by Alliance of Genome Resources, Jul 2025] | 2 | 29980956 | 29983647 | Mouse | 79 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1320235 | Zdhhc13 | zinc finger, DHHC domain containing 13 | Enables magnesium ion transmembrane transporter activity and palmitoyltransferase activity. Predicted to be involved in magnesium ion transmembrane transport. Located in Golgi membrane and Golgi-associated vesicle membrane. Is expressed in several structures, including early conceptus; esophagus epi thelium; genitourinary system; molar; and sensory organ. Used to study Huntington's disease. Orthologous to human ZDHHC13 (zinc finger DHHC-type palmitoyltransferase 13). [provided by Alliance of Genome Resources, Jul 2025] | 7 | 48438751 | 48477188 | Mouse | 143 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1558404 | Zdhhc14 | zinc finger, DHHC domain containing 14 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation and protein targeting to membrane. Predicted to be located in Golgi membrane and endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus and endopl asmic reticulum. Is expressed in oocyte. Orthologous to human ZDHHC14 (zinc finger DHHC-type palmitoyltransferase 14). [provided by Alliance of Genome Resources, Jul 2025] | 17 | 5542220 | 5810517 | Mouse | 120 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1558080 | Zdhhc15 | zinc finger, DHHC domain containing 15 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in peptidyl-L-cysteine S-palmitoylation. Acts upstream of or within establishment of protein localization and synaptic vesicle maturation. Located in Golgi apparatus. Is expressed in embryo and eye. Orthologous to human ZDHH 'font-weight:700;'>DHHC15 (zinc finger DHHC-type palmitoyltransferase 15). [provided by Alliance of Genome Resources, Jul 2025] | X | 103580575 | 103714696 | Mouse | 89 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1623929 | Zdhhc16 | zinc finger, DHHC domain containing 16 | Enables palmitoyltransferase activity. Involved in several processes, including DNA damage response; eye development; and protein palmitoylation. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in Golgi apparatus. Is expressed in several structures, including early conceptus; eye; genitourinary system; heart; and trunk somite. Orthologous to human ZDHHC16 (zinc finger DHHC-type palmitoyltransferase 16). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 41921884 | 41932543 | Mouse | 101 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1557918 | Zdhhc17 | zinc finger, DHHC domain containing 17 | Enables palmitoyltransferase activity and signaling receptor binding activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of modification of synapse structure, modulating synaptic transmission; and regulation of signal transduction. Located in Golgi app aratus. Is active in glutamatergic synapse; perforant pathway to dendrate granule cell synapse; and postsynaptic Golgi apparatus. Is expressed in several structures, including early conceptus; heart; and oocyte. Used to study Huntington's disease. Orthologous to human ZDHHC17 (zinc finger DHHC-type palmitoyltransferase 17). [provided by Alliance of Genome Resources, Jul 2025] | 10 | 110777640 | 110848587 | Mouse | 126 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1551232 | Zdhhc18 | zinc finger, DHHC domain containing 18 | Enables palmitoyltransferase activity. Acts upstream of or within protein localization. Predicted to be located in Golgi membrane and cytosol. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC18 (zinc finger DHH yle='font-weight:700;'>DHHC-type palmitoyltransferase 18). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 133331969 | 133360801 | Mouse | 97 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1319120 | Zdhhc19 | zinc finger, DHHC domain containing 19 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in peptidyl-L-cysteine S-palmitoylation; positive regulation of aggrephagy; and protein targeting to membrane. Predicted to be located in Golgi membrane and perinucleolar compartment. Predicted to be activ e in Golgi apparatus and endoplasmic reticulum. Orthologous to human ZDHHC19 (zinc finger DHHC-type palmitoyltransferase 19). [provided by Alliance of Genome Resources, Apr 2025] | 16 | 32315059 | 32326032 | Mouse | 89 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, PROVISIONAL [RefSeq] |
| 1553018 | Zdhhc20 | zinc finger, DHHC domain containing 20 | Predicted to enable protein-cysteine S-palmitoyltransferase activity and zinc ion binding activity. Predicted to be involved in several processes, including peptidyl-L-cysteine S-palmitoylation; positive regulation by host of viral process; and synaptic vesicle maturation. Predicted to be located in Golgi membrane and plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in early conceptus; inner cell mass; and oocyte. Orthologous to human ZDHHC20 (zinc finger DHHC-type palmitoyltransferase 20). [provided by Alliance of Genome Resources, Apr 2025] | 14 | 58070159 | 58128288 | Mouse | 107 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1313970 | Zdhhc21 | zinc finger, DHHC domain containing 21 | Enables protein-cysteine S-palmitoyltransferase activity. Involved in several processes, including peptidyl-L-cysteine S-palmitoylation; regulation of establishment of endothelial barrier; and regulation of vascular associated smooth muscle contraction. Acts upstream of or within hair follicle devel opment; protein palmitoylation; and sebaceous gland development. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in early conceptus; eye; inner cell mass; oocyte; and trunk somite. Orthologous to human ZDHHC21 (zinc finger DHHC-type palmitoyltransferase 21). [provided by Alliance of Genome Resources, Jul 2025] | 4 | 82716975 | 82778892 | Mouse | 132 | symbol , old_gene_name , PhenoGen , name , description , old_gene_symbol | gene, protein-coding, VALIDATED [RefSeq] |
| 1620581 | Zdhhc22 | zinc finger, DHHC-type containing 22 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Acts upstream of or within protein localization to plasma membrane and protein palmitoylation. Predicted to be located in plasma membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Orthologous to human Z DHHC22 (zinc finger DHHC-type palmitoyltransferase 22). [provided by Alliance of Genome Resources, Jul 2025] | 12 | 87027537 | 87037604 | Mouse | 58 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1618774 | Zdhhc23 | zinc finger, DHHC domain containing 23 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Acts upstream of or within protein localization to plasma membrane and protein palmitoylation. Predicted to be located in Golgi membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including central nervous system; ileum; metanephros; reproductive system; and respiratory system. Orthologous to human ZDHHC23 (zinc finger DHHC-type palmitoyltransferase 23). [provided by Alliance of Genome Resources, Jul 2025] | 16 | 43785396 | 43800295 | Mouse | 92 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1557474 | Zdhhc24 | zinc finger, DHHC domain containing 24 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein targeting to membrane. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum. Is expressed in several structures, including brain; early concep tus; endocrine gland; genitourinary system; and spinal cord mantle layer. Orthologous to human ZDHHC24 (zinc finger DHHC-type containing 24). [provided by Alliance of Genome Resources, Jul 2025] | 19 | 4928696 | 4935425 | Mouse | 46 | symbol , old_gene_name , PhenoGen , name , description | gene, protein-coding, VALIDATED [RefSeq] |
| 1558490 | Zdhhc25 | zinc finger, DHHC domain containing 25 | Predicted to enable protein-cysteine S-palmitoyltransferase activity. Predicted to be involved in protein localization to plasma membrane; protein targeting to membrane; and regulation of G protein-coupled receptor signaling pathway. Predicted to be active in Golgi apparatus and endoplasmic reticulu m. Is expressed in testis. [provided by Alliance of Genome Resources, Jul 2025] | 15 | 88484505 | 88485872 | Mouse | 15 | symbol , PhenoGen , name | gene, protein-coding, VALIDATED [RefSeq] |
| 737404 | Coq3 | coenzyme Q3 methyltransferase | Predicted to enable 3-demethylubiquinol 3-O-methyltransferase activity and polyprenyldihydroxybenzoate methyltransferase activity. Predicted to be involved in glycerol metabolic process; methylation; and ubiquinone biosynthetic process. Located in mitochondrion. Is active in mitochondrial matrix. Is expressed in heart and heart right ventricle. Orthologous to human COQ3 (coenzyme Q3, methyltransferase). [provided by Alliance of Genome Resources, Apr 2025] | 4 | 21879646 | 21912163 | Mouse | 159 | old_gene_name | gene, protein-coding, VALIDATED [RefSeq] |